STEM Integrity 10 Reaction Block

Transcription

1 STEM Integrity 10 Reactin Blck The STEM Integrity 10 Reactin Blck is an excellent screening tl that can be used in mst labratries, with: 10 individual cells in ne reactin blck Individual cntrl f temperature and stirring rate fr each cell Temperature range f -30 C t 150 C Stirring rate f 250 rpm rpm Cell wrking vlume f 2ml- 25ml Optinal attachments fr refluxing, and wrking under vacuum r inert gas cnditins Optinal multi-infrared prbes fr slubility / crystallisatin studies Autmatic micrprcessr cntrl thrugh a tuchscreen It has ptential applicatins in a range f industries, including the petrchemical, chemical, pharmaceutical and fd prcessing industries, as almst every labratry culd use this highly efficient screening tl.

2 Intrducing the Integrity 10 STEM Integrity 10 Reactin Blck The STEM Integrity 10 Reactin Blck enables yu t cnduct 10 different reactins simultaneusly within the same reactin blck, each reactin being cnducted within its wn cell, at its wn individual temperature and stir rate. If desired, fast heating and cling rates can be selected, with temperature ramps f between 0.5 C/min t 5 C/min. There is als a crash functin fr even faster temperature changes, which is ideal fr kinetic determinatins. Extreme temperature accuracy is guaranteed, with a temperature stability f ± 0.2 C and a minimal set pint versht f 0.5 C. The temperature may be maintained either thrugh the blck itself r by using a prbe within each cell s slutin. This accuracy can be maintained ver a wide temperature range f -30 C t 150 C, with precise, independently cntrlled temperature prfiles, and hmgeneus sample mixing may be assured with stirring rates f between 250rpm t 1200rpm using magnetic stirrers. With wrking vlumes f between 2ml t 25ml, the STEM Integrity 10 is an excellent screening tl fr mst labratries and can als be used t establish ideal prcess cnditins. Optimised cell design Temperature range: -30 C t 150 C Temperature ramp rate: 0.5 C/min t 5 C/min Temperature stability ± 0.2 C Minimal set pint versht: 0.5 C Stirring rates: 250rpm 1200rpm Wrking vlumes: 2ml- 25ml Key features 10 individual cells in ne reactin blck Individual cntrl f temperature and stirring rate fr each cell Temperature range f -30 C t 150 C Stirring rate f 250 rpm rpm Cell wrking vlume f 2ml- 25ml Optinal attachments fr refluxing, and wrking under vacuum r inert gas cnditins Optinal multi-infrared prbes fr slubility/ crystallisatin studies Autmatic micrprcessr cntrl thrugh a tuchscreen Fr mre infrmatin, please visit:

3 A highly efficient screening tl The STEM Integrity 10 Reactin Blck is a very timeefficient way f cnducting chemical experiments, speeding up investigative chemistry by up t 10-fld. Chemical reactins, invlving either synthetic chemicals r naturally ccurring substances, are universally impacted by heat and the STEM Integrity 10 lets yu assess the impact f bth temperature and stirring rate upn reactins. The beauty f the STEM Integrity 10 is that it cmbines flexibility with accuracy: It allws yu t run 10 experimental variants simultaneusly within the same reactin blck, whse temperature and stir rate yu can precisely and individually cntrl. Yu can design temperature prfiles fr each individual experiment and recrd everything electrnically; all results are captured and stred autmatically, s yu can be wrking (r relaxing) elsewhere whilst the STEM Integrity 10 has everything under cntrl....and fr establishing ideal prcess cnditins Whilst there is bvius ptential fr screening reactins in investigative chemistry r drug discvery labratries, let s nt frget abut prcess mnitring labratries. The STEM Integrity 10 can be very useful fr establishing the ideal reactin cnditins f many industrial chemical prcesses and can mre than earn its keep as a great truble-shter, pinpinting the cause f prcess malfunctins due t temperature. It saves time, bench space and electricity, is easy t clean, and since the wrking vlume f each reactin cell is between 2 and 25ml, it is very ecnmical n reagents as well. Yu can further refinements t increase the usefulness f this apparatus, fr example, by adding reflux cndensers, r using PTFE gas inlet/utlet heads fr wrking under vacuum cnditins r inert gas cnditins with a nitrgen r argn blanket. The pssibilities fr attachments are endless, and t illustrate this, we have develped a Clarity System which utilises the STEM Integrity 10 t cnduct slubility and crystallisatin studies. Fr mre infrmatin, please visit:

4 Intuitive and easy peratin Cmplete cntrl at yur fingertips Althugh a sphisticated tl, the STEM Integrity 10, whether perating by itself r as part f the full Clarity System, is a jy t use and des nt require frmal training, designed t be ut f the bx t peratinal within 10 minutes. The integrated micrprcessr is cntrlled thrugh a user-friendly 145 mm tuchscreen, which greatly simplifies peratin and enables rapid at a glance assessment f each critical parameter in the reactin. The curse f the reactin within each cell may be mnitred directly n this tuchscreen, enabling trend analysis (e.g. fr slubility tests using turbidity measurements) t be dne withut needing t cnnect t a laptp. Hwever, shuld yu require this, all data is dwnladable thrugh a USB prt t a PC, USB strage device r SD card. The tuchscreen menu is intuitive, with clear icns t reduce the ptential fr cstly errrs. Pre-prgrammed prfiles may be set up fr rutine measurements, and there is als a manual verride ptin t prgramme set pints and ramps fr individual prcesses if required. Simplicity itself: 5 Step tuchscreen peratin 1 Switch n the tuchscreen 3 Inclusin f heating/cling ramps Click n the buttn t the left f the hme screen t switch n the tuchscreen. The tuchscreen allws yu t set up cling and heating ramps and establish a temperature prfile fr each cell. Yu can set up cycle runs t by chsing hw many times yu wuld like this prfile t repeat. 2 Chse yur prfile The ptins n the tuchscreen ffer yu the chice f running a manual r autmatic prfile. 4 Autmatic warnings In the event f any prblem, yu are autmatically alerted thrugh warnings n the tuchscreen. This ensures that yu remain in cntrl f the prcess, and that the prfile yu have prgrammed in is running as planned. 5 Mnitr results visually Mnitr the results f yur experiments as they happen, displayed n the mnitr. Fr mre infrmatin, please visit:

5 Micrprcessr tuchscreen Cmplete cntrl at yur fingertips The frnt-munted 145 mm micrprcessr tuchscreen is simplicity itself t perate, giving yu cmplete cntrl ver the temperature and stirring cnditins f each cell in the reactin blck. Key features f the user friendly menu Chice f temperature prfile and stirring parameters Prmpts t guide yu in yur selectins Intuitive icns t reduce the ptential fr cstly errrs Real-time editing f ramp rates, run times and set pints Tailred temperature prfiles Curves can be prgrammed int the temperature prfiles Integrated data base ptins fr frequently used prfiles Flexibility as all parameters can be changed during the prcess Visibility f each cell n the micrprcessr screen t prvide immediate and n-ging access t the prgress f the reactins within each cell Autmatic functins fr: Recrding f the reactin prfile fr each cell fr all imprtant parameters Scaling f data Aut-calibratin Self-diagnstic warning system t flag any errrs immediately Histrical recrds: All data is captured and can be viewed histrically Extensive strage capability Prtectin f run event histry lgs thrugh user pass cdes and cntrl lckuts Data is extractable t a PC via a USB prt r SD card fr mre in-depth analysis and evaluatin f the results There is an ptinal replaceable water-cled reflux cndenser fr efficient and cntinuus sample refluxing. At-a-glance display f the results graphically Fr mre infrmatin, please visit:

6 Chice f frmats The STEM Integrity 10 Reactin Blck is available in tw frmats depending upn yur needs: Optin 1: STEM Integrity 10 Reactin Blck by itself Optin 2: Clarity System, which cnsists f the STEM Integrity 10 Reactin Blck, with additinal slubility and crystallisatin evaluatin apparatus and sftware. Optin 1 The STEM Integrity 10 unit Optin 1, the STEM Integrity 10 unit by itself, is generally useful fr a wide range f reactins r prcesses in which temperature plays a majr rle, regardless f the industry. Within a temperature band f -30 C t 150 C, it is applicable whether these prcesses are derived frm the petrchemical, chemical, pharmaceutical r fd prcessing industries. Different attachments may be added t these reactin cells, such as reflux heads t minimise evapratin and lss f liquid, r PTFE caps fr maintaining an inert gas envirnment, t expand the range f uses fr the STEM Integrity 10 Reactin Blck. One attachment that has been specifically designed fr the STEM Integrity 10 is a multi-infrared (IR) prbe, which is available in intrusive r nn-intrusive frmats. This prbe detects infrared transmissin, and via turbidity measurements, can be used t determine slubility characteristics f slutins. This is available as Optin 2, the full Clarity System. Optin 2 The Clarity System Optin 2, the Clarity System, is finding increasing use in the pharmaceutical, petrchemical and fd industries fr specialist applicatins. Develped in cllabratin with partners at Pfizer and the Illinis Institute f Technlgy, the Integrity 10 STEM reactin statin with integrated sftware is a pwerful tl fr determining slubility and crystallisatin prfiles. Precise heating and data cllectin f up t 10 reactr cells in parallel prvides rapid measurement f slubility under a range f cnditins, whilst individual infrared transmissin detectrs allw turbidity/slubility measurements t be perfrmed t a standardised endpint (threshld). It is envisaged that the full Clarity System wuld be a great aid in determining the slubility f drugs, the bidegradability f ils, and the crystallisatin characteristics f cca butter t name just a few ptential applicatins. Fr mre infrmatin, please visit:

7 Ordering infrmatin Catalgue n. Descriptin PS20000 Integrity 10 with 10 individually cntrlled cells Fr 110V, add X1 suffix Fr 230V with EU plug, add X6 suffix ATS20000 Integrity 10 reflux cndenser ATS10377 PTFE cap with valve and sensr inlet (pack f 10) ATS10075 Glass tubes 24/150mm (pack f 10) AZ4206 Stirrer bars 10/6mm (pack f 10) AZ4235 Stirrer bars 12/4.5mm (pack f 10) ATS10001 Multi-Temp10 Mdule ATS10027 Thermcuple prbe (pack f 6) ATS11005 Integrity sftware ATS Nn-intrusive IR sensr ATS10230 Intrusive IT prbe in stainless steel ATS10230H Intrusive IR prbe in Hastelly (nickel-based ally with high crrsin resistance) ATS10232 Multi-IR bx Technical specificatin Number f cell psitins 10 Cell cavity diameter 25.5mm Glass vessel fill level 2-25ml Temperature range -30 C t 150 C Temperature difference between any tw psitins 180 C Temperature versht 0.1 C Maximum heating/cling rate 5 C/min Temperature ramp rate 0.1 C/min t 5 C/min in 0.1 C/min steps Stir speed range rpm Maximum viscsity capacity Glycerine at 25 C Recmmended stir bars 12/4.5mm (cylindrical) r 10/6mm (val) Measurement Temperature: Range -40 C t 160 C Reslutin 0.01 C Accuracy 0.5 C Stirrer: Speed range rpm Reslutin 1 rpm/min Accuracy 10 rpm/min Viscsity: Range arbitrary units Reslutin 1 arbitrary unit Measured external temperature (ptinal thermmeter) range Range -40 C t 160 C Reslutin 0.01 C Accuracy 1.5 C Minimum temperature is linearly dependent upn the temperature f the cling fluid. Specified range assumes a cling fluid temperature supply f between 0 C t -5 C at a flw rate f 2.5L/min and a cling capacity f 1000W Stir perfrmance nly guaranteed using recmmended stir bars Fr mre infrmatin, please visit:

8 Als available in the Electrthermal range EM Electrmantles EM Electrmantle heating mantles are used in wet chemistry t heat liquids in rund bttm flasks. The plastic case is designed t remain cl-t-the-tuch when in peratin. Electrthermal heating mantles have a grunded stainless steel earth screen cvering the element and are duble fused fr added safety. EMA Electrmantle Heating and Stirring Mantles EMA mdels have all the features f the EM range f heating mantles with the additin f variable speed stirring in single directin r aut reverse mdes. EMV and EMX V -Shaped Electrmantles EMV heating mantles accept a large range f flask and funnel sizes and are available with extra spill-prf prtectin as the EMX range. EME Extractin Heaters The Electrmantle extractin heaters are available with six r three recesses and feature a durable chemically resistant plyprpylene tp casing. All versins have built in electrnic cntrllers and a wide range f flask sizes can be accmmdated, with r withut stirring. Macr-Kjeldahl The Macr-Kjeldahl Extractin Heaters accept vlume sizes frm 80 t 800ml. Individual builtin cntrllers regulate quartz fibre heating elements up t 550ºC t 800ºC. These multibank units have a stainless steel husing that accepts an integral glassware supprt. Micr-Kjeldahl The Micr-Kjeldahl Extractin Heaters accept vlume sizes frm 18 t 50ml. Individual built-in cntrllers regulate quartz fibre heating elements up t 550ºC t 800ºC. These multibank units have a stainless steel husing that accepts an integral glassware supprt. Cntrllers The Electrthermal Cntrllers include a range f mdels fr single, duble and triple place and percentage ff/n. Cntrller line includes the ideal cntrller t pair with yur heating mantles, crds and tapes. A Bibby Scientific Cmpany Electrthermal Huse, Unit 12A Purdeys Way, Purdeys Industrial Estate, Rchfrd, Essex, SS4 1ND, United Kingdm t: +44 (0) f: +44 (0) Fllw Electrthermal n FaceBk! Fllw Electrthermal n Twitter! w w w. t w i t t e r. c m / e l e c t r t h e r m a l Electrthermal vides nw n Yutube! w w w. y u t u b e. c m / b i b b y s c i e n t i f i c Issue N. Fr mre infrmatin: