This syllabus is based on 15 weeks (45 class periods), MWF.

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1 Sample Syllabi for Chapters 1-15 of, by AM Campbell, L J Heyer, C J Paradise, focusing on the molecular, cellular and organismal levels of the biological hierarchy This syllabus is based on 15 weeks (45 class periods), MWF. This syllabus also allows for 3 in- class tests and an additional final outside class time. The typical structure of a class period is centered around discussing the data in a section with the students. You can have them work in small groups or cold call students to ask them questions, including Integrating Questions. Students should prepare for class by reading each assigned section and analyzing and working through the IQs, data, and BMEs. Semester of small bio taught as a MWF class; 15 week version (some sections skipped) Week Big Idea Chapter Section/Topic/Notes 1 Info 0, 1 M: Introduction to course; Chapter 0 W: 1.1 What is biological information?; 1.2 What is the heritable material?; BME 1.1 F: 1.3 Can you prove protein is NOT the heritable material?; ELSI Info 1, 2 M: 1.4 How does DNA s shape affect its function?; BME 1.2; BME 1.3 W: 1.5 Is all genetic information encoded linearly in the DNA sequence? F: 2.1 How does DNA communicate information to the cell?; ELSI Info 2, 3 M: 2.2 How is gene transcription regulated?; BME 2.1; BME 2.2 W: 2.3 How do cells make proteins?; 2.4 Can cells pick and choose information?; ELSI 2.2 F: 3.1 How can traits disappear and reappear in a later generation?; BME 3.1 and BME Info, Evo 3 M: 3.2 What happens when you follow two traits at once?; ELSI 3.1; 3.3 How do prokaryotes communicate their identity to the next generation?; BME 3.3 W: 3.4 Do eukaryotes produce new cells the same way as bacteria?; 3.5 How can two parents produce non- identical offspring?; ELSI 3.2 F: Test #1 for Chapters Evo 4 M: 4.1 What is evolution?; ELSI 4.1; first half 4.2 Could abiotic molecules form biologically important molecules before life evolved? W: finish 4.2 Could abiotic molecules form biologically important molecules before life evolved?; BME 4.1; 4.3 Can non- living objects compete and grow?; BME 4.2 F: 4.4 Can non- living objects harvest and store energy?; BME 4.3 1

2 (short chapter, time to finish 4.3 & BME 4.2) 6 Evo 5 M: 5.1 How do genetic diseases arise?; start 5.2: How are new species formed?; BME 5.1 W: finish 5.2: How are new species formed?; ELSI 5.1 F: 5.3 Why do my allergies get worse each year?; ELSI Evo, Cell 6, 7 M: 6.1 How did the first nucleus come into being?; ELSI 6.1 W: 6.3 How did mitochondria and chloroplasts originate?; 6.4 How did multicellular organisms evolve?; BME 6.1 & BME 6.2; F: 7.1 What role does molecular structure play in a cell s function?; start 7.2 How do cells respond to fear?; optional to carry over Chapter six, 6.2 How does a whole genome fit inside a tiny nucleus? 8 Cell 7 M: finish 7.2 How do cells respond to fear?; ELSI 7.1 W: finish 7.2 and ELSI; 7.3 Why are some membranes wavy? F: Test #2 for Chapters Cell 8, 9 M: 8.1 What is a cell?? W: 8.2 Why aren t there giant cells?; BME 8.1; BME 8.2; ELSI 8.1; optional 8.3 Are viruses alive? F: 9.1 How do I tell my muscles to move?; BME Cell, Hom 9, 10 M: 9.2 How do muscles respond to exercise?; ELSI 9.1 W: 9.3 How do brain cells store memories?; ELSI 9.2 F: 10.1 How do biological molecules carry energy?; start 10.2 How does food get converted to molecular energy? 11 Hom 10, 11 M: finish 10.2 How does food get converted to molecular energy?; ELSI 10.1; 10.3 How is energy extracted from 2- carbon intermediates? W: 10.4 How is ATP produced?; BME 10.1; ELSI 10.2 F: 11.1 Why is paraquat used in America but illegal in Europe? 12 Hom 11, 12 M: 11.2 How does Brazil s rainforest affect Greenland s glaciers?; ELSI 11.1; optional 11.3 Is there anywhere on earth devoid of life?; optional BME 11.1 W: Test #3 for Chapters 8-11 F: 12.1 How do plants respond to changes when they can t move?; 12.2; OR How can changes in two cells affect an entire plant?; BME 12.1; OR 12.3 How does a Venus flytrap catch its prey?; ELSI 12.1 Can do one or two sections, choose your favorite 13 E P 13 M: 13.1 What are emergent properties?; 13.2 How does blood carry oxygen?; BME 13.1 W: 13.3 When does a virus kill its host? F: 13.4 Does the genome allow random actions by cells?; ELSI E P 14, 15 M: 14.1 How do single- celled organisms communicate with one another?; ELSI 14.1 W: 14.2 Do unicellular species have to work solo?; BME 14.1 OR 14.3 Can cells tell time?; OR 15.1 How do mammals tell time?; 2

3 Choose one of three sections F: 15.2 How can a mother tolerate her fetus? 15 E P 15 M: 15.3 How do we maintain our weight?; ELSI 15.2; BME 15.1; BME 15.2 W: 15.4 Why do individuals age and die?; ELSI 15.3 F: Final/Test #4 for Chapters

4 This syllabus is based on 14 weeks (42 class periods), MWF. This syllabus also allows for 3 in- class tests and an additional final outside class time. The typical structure of a class period is centered around discussing the data in a section with the students. You can have them work in small groups or cold call students to ask them questions, including Integrating Questions. Students should prepare for class by reading each assigned section and analyzing and working through the IQs, data, and BMEs. Semester of small bio taught as a MWF class; 14 week version (some sections skipped) Week Big Idea Chapter Section/Topic/Notes 1 Info 0, 1 M: Introduction to course; Chapter 0 W: 1.1 What is biological information?; 1.2 What is the heritable material?; BME 1.1 F: 1.3 Can you prove protein is NOT the heritable material?; ELSI Info 1, 2 M: 1.4 How does DNA s shape affect its function?; BME 1.2; BME 1.3 W: 1.5 Is all genetic information encoded linearly in the DNA sequence? F: 2.1 How does DNA communicate information to the cell?; ELSI Info 2, 3 M: 2.2 How is gene transcription regulated?; BME 2.1; BME 2.2 W: 2.3 How do cells make proteins?; 2.4 Can cells pick and choose information?; ELSI 2.2 F: 3.1 How can traits disappear and reappear in a later generation?; BME 3.1 and BME Info, Evo 3 M: 3.2 What happens when you follow two traits at once?; ELSI 3.1; 3.3 How do prokaryotes communicate their identity to the next generation?; BME 3.3 W: 3.4 Do eukaryotes produce new cells the same way as bacteria?; 3.5 How can two parents produce non- identical offspring?; ELSI 3.2 F: Test #1 for Chapters Evo 4 M: 4.1 What is evolution?; ELSI 4.1; first half 4.2 Could abiotic molecules form biologically important molecules before life evolved? W: finish 4.2 Could abiotic molecules form biologically important molecules before life evolved?; BME 4.1; 4.3 Can non- living objects compete and grow?; BME 4.2 F: 4.4 Can non- living objects harvest and store energy?; BME 4.3 (short chapter, time to finish 4.3 & BME 4.2) 6 Evo 5, 6 M: 5.1 How do genetic diseases arise?; 5.2: How are new species formed?; BME 5.1; ELSI 5.1 W: 5.3 Why do my allergies get worse each year?; ELSI 5.2 F: 6.1 How did the first nucleus come into being?; ELSI 6.1; 6.2 How 4

5 does a whole genome fit inside a tiny nucleus?; 6.3 How did mitochondria and chloroplasts originate? Chose two of three Sections 7 Cell 7 M: 7.1 What role does molecular structure play in a cell s function? F:; start 7.2 How do cells respond to fear? W: finish 7.2 How do cells respond to fear?; ELSI 7.1 F: 7.3 Why are some membranes wavy? 8 Cell 8 M: Test #2 for Chapters 4-7 W: 8.1 What is a cell?; 8.2 Why aren t there giant cells?; BME 8.1; BME 8.2; ELSI 8.1; skim 8.2 and spend more time on 8.3 F: 9.1 How do I tell my muscles to move?; BME Cell, Hom 9, 10 M: 9.2 How do muscles respond to exercise?; ELSI 9.1 W: 9.3 How do brain cells store memories?; ELSI 9.2 F: 10.1 How do biological molecules carry energy?; start 10.2 How does food get converted to molecular energy? 10 Hom 10, 11 M: finish 10.2 How does food get converted to molecular energy?; ELSI 10.1; 10.3 How is energy extracted from 2- carbon intermediates? W: 10.4 How is ATP produced?; BME 10.1; ELSI 10.2 F: 11.1 Why is paraquat used in America but illegal in Europe? 11 Hom 11, 12 M: 11.2 How does Brazil s rainforest affect Greenland s glaciers?; ELSI 11.1; optional 11.3 Is there anywhere on earth devoid of life?; optional BME 11.1 W: Test #3 for Chapters 8-11 F: 12.1 How do plants respond to changes when they can t move?; 12.2; OR How can changes in two cells affect an entire plant?; BME 12.1; OR 12.3 How does a Venus flytrap catch its prey?; ELSI 12.1 Can do one or two sections, choose your favorite 12 E P 13 M: 13.1 What are emergent properties?; 13.2 How does blood carry oxygen?; BME 13.1 W: 13.3 When does a virus kill its host? F: 13.4 Does the genome allow random actions by cells?; ELSI E P 14, 15 M: 14.1 How do single- celled organisms communicate with one another?; ELSI 14.1 W: 14.2 Do unicellular species have to work solo?; BME 14.1 OR 14.3 Can cells tell time?; Choose one section F: 15.2 How can a mother tolerate her fetus? 14 E P 15 M: 15.3 How do we maintain our weight?; ELSI 15.2; BME 15.1; BME 15.2 W: 15.4 Why do individuals age and die?; ELSI 15.3 F: Final/Test #4 for Chapters

6 This syllabus is based on 15 weeks (30 class periods), T/Th. This syllabus also allows for 3 in- class tests and an additional final outside class time. The typical structure of a class period is centered around discussing the data in a section with the students. You can have them work in small groups or cold call students to ask them questions, including Integrating Questions. Students should prepare for class by reading each assigned section and analyzing and working through the IQs, data, and BMEs. Semester of small bio taught as a T/Th class; 15 week version (some sections skipped) Week Big Idea Chapter Section/Topic/Notes 1 Info 0, 1 T: Introduction to course; Chapter 0; 1.1 What is biological information? TH: 1.2 What is the heritable material?; BME 1.1; 1.3 Can you prove protein is NOT the heritable material?; ELSI Info 1, 2 T: 1.4 How does DNA s shape affect its function?; BME 1.2; BME 1.3; 1.5 Is all genetic information encoded linearly in the DNA sequence? TH: 2.1 How does DNA communicate information to the cell?; ELSI 2.1; start 2.2 How is gene transcription regulated?; BME 2.1; BME Info 2, 3 T: finish 2.2 How is gene transcription regulated?; BME 2.1; BME 2.2; 2.3 How do cells make proteins?; 2.4 Can cells pick and choose information?; ELSI 2.2 TH: 3.1 How can traits disappear and reappear in a later generation?; BME 3.1 and BME 3.2; 3.2 What happens when you follow two traits at once?; ELSI Info 3 T: 3.3 How do prokaryotes communicate their identity to the next generation?; BME 3.3; 3.4 Do eukaryotes produce new cells the same way as bacteria?; 3.5 How can two parents produce non- identical offspring?; ELSI 3.2 TH: Test #1 for Chapters Evo 4 T: 4.1 What is evolution?; ELSI 4.1; 4.2 Could abiotic molecules form biologically important molecules before life evolved?; BME 4.1; TH: 4.3 Can non- living objects compete and grow?; BME 4.2; 4.4 Can non- living objects harvest and store energy?; BME Evo 5 T: 5.1 How do genetic diseases arise?; 5.2: How are new species formed?; BME 5.1; ELSI 5.1 TH: 5.3 Why do my allergies get worse each year?; ELSI 5.2 May need to finish 5.2 from Tuesday. 7 Evo, Cell 6, 7 T: 6.1 How did the first nucleus come into being?; ELSI 6.1; 6.2 How does a whole genome fit inside a tiny nucleus?; 6.3 How did 6

7 mitochondria and chloroplasts originate? Chose two of three Sections TH: 7.1 What role does molecular structure play in a cell s function?; 7.2 How do cells respond to fear?; ELSI Cell 8 T: Test #2 for Chapters 4-7 TH: 8.1 What is a cell?; 8.2 Why aren t there giant cells?; BME 8.1; BME 8.2; ELSI Cell, Hom 9, 10 T: 9.1 How do I tell my muscles to move?; BME 9.1; 9.2 How do muscles respond to exercise?; ELSI 9.1 TH: 9.3 How do brain cells store memories?; ELSI 9.2; 10.1 How do biological molecules carry energy? 10 Hom 10 T: 10.2 How does food get converted to molecular energy?; ELSI 10.1 TH: 10.3 How is energy extracted from 2- carbon intermediates?; 10.4 How is ATP produced?; BME 10.1; ELSI Hom 11 T: 11.1 Why is paraquat used in America but illegal in Europe?; 11.2 How does Brazil s rainforest affect Greenland s glaciers?; ELSI 11.1 TH: Test #3 for Chapters Hom, E P 12, 13 T: 12.1 How do plants respond to changes when they can t move?; 12.2; OR How can changes in two cells affect an entire plant?; BME 12.1; OR 12.3 How does a Venus flytrap catch its prey?; ELSI 12.1 Can do one or two sections, choose your favorite TH: 13.1 What are emergent properties?; 13.2 How does blood carry oxygen?; BME 13.1; start 13.3 When does a virus kill its host? 13 E P 13, 14 T: finish 13.3 When does a virus kill its host?; 13.4 Does the genome allow random actions by cells?; ELSI 13.1 TH: 14.1 How do single- celled organisms communicate with one another?; ELSI 14.1; OR 14.2 Do unicellular species have to work solo?; BME 14.1 OR 14.3 Can cells tell time?; OR 15.1 How do mammals tell time?; Choose two of four sections 14 E P 14, 15 T: 28.1 How do mammals stay warm in the winter and cool in the summer?; ELSI 28.1; 28.2 How does foraging of an individual affect the population? TH: 15.2 How can a mother tolerate her fetus?; start 15.3 How do we maintain our weight? 15 E P 15 T: finish 15.3 How do we maintain our weight?; ELSI 15.2; BME 15.1; BME 15.2; 15.4 Why do individuals age and die?; ELSI 15.3 TH: Final/Test #4 for Chapters

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