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1 LEARNING OBJECTIVES FOR EACH BIG IDEA WITH ASSOCIATED SCIENCE PRACTICES AND ESSENTIAL KNOWLEDGE Learning Objectives will be the target for AP Biology exam questions Learning Objectives Sci Prac Es Knowl 1.1 The student is able to convert a data set from a table of numbers that reflect a change in the genetic makeup of a 1.5 1A1 population over time and to apply mathematical methods and conceptual understandings to investigate the cause(s) and effect(s) of this change The student is able to evaluate evidence provided by data to qualitatively and quantitatively investigate the role 2.2 1A1 of natural selection in evolution The student is able to apply mathematical methods to data from a real or simulated population to predict what 2.2 1A1 will happen to the population in the future. 1.4 The student is able to evaluate data-based evidence that describes evolutionary 5.3 1A2 changes in the genetic makeup of a population over time. 1.5 The student is able to connect evolutionary changes in a population over time to a change in the environment A2 1.6 The student is able to use data from mathematical models based on the Hardy-Weinberg equilibrium to analyze 1.4 1A3 genetic drift and effects of selection in the evolution of specific populations The student is able to justify data from mathematical models based on the Hardy-Weinberg equilibrium to analyze 2.1 1A3 genetic drift and the effects of selection in the evolution of specific populations. 1.8 The student is able to make predictions about the effects of genetic drift, migration and artificial selection on the 6.4 1A3 genetic makeup of a population. 1.9 The student is able to evaluate evidence provided by data from many scientific disciplines that support biological evolution A The student is able to refine evidence based on data from many scientific disciplines that support biological evolution The student is able to design a plan to answer scientific questions regarding how organisms have changed over time using information from morphology, biochemistry and geology The student is able to connect scientific evidence from many scientific disciplines to support the modern concept of evolution The student is able to construct and/or justify mathematical models, diagrams or simulations that represent processes of biological evolution The student is able to pose scientific questions that correctly identify essential properties of shared, core life processes that provide insights into the history of life on Earth 1.15 The student is able to describe specific examples of conserved core biological processes and features shared by all domains or within one domain of life, and how these shared, conserved core processes and features support the concept of common ancestry for all organisms A A A A B B The student is able to justify the scientific claim that organisms share many conserved core processes and features that evolved and are widely distributed among organisms 6.1 1B1 Page1

3 Learning Objective Sci Prac Es Knowl 2.1 The student is able to explain how biological systems use free energy based on empirical data that all organisms require 6.2 2A1 constant energy input to maintain organization, to grow and to reproduce. 2.2 The student is able to justify a scientific claim that free energy is required for living systems to maintain organization, to 6.1 2A1 grow or to reproduce, but that multiple strategies exist in different living systems 2.3 The student is able to predict how changes in free energy availability affect organisms, populations and ecosystems A1 2.4 The student is able to predict how changes in free energy availability affect organisms, populations and ecosystems A The student is able to construct explanations of the mechanisms and structural features of cells that allow organisms to 6.2 2A2 capture, store or use free energy. 2.6 The student is able to use calculated surface area-to-volume ratios to predict which cell(s) might eliminate wastes or 2.2 2A3 procure nutrients faster by diffusion. 2.7 Students will be able to explain how cell size and shape affect the overall rate of nutrient intake and the rate of waste 6.2 2A3 elimination. 2.8 The student is able to justify the selection of data regarding the types of molecules that an animal, plant or bacterium will 4.1 2A3 take up as necessary building blocks and excrete as waste products. 2/9 The student is able to represent graphically or model quantitatively the exchange of molecules between an organism and its environment, and the subsequent use of these molecules to build new molecules that facilitate dynamic homeostasis, growth and reproduction A The student is able to use representations and models to pose scientific questions about the properties of cell membranes and selective permeability based on molecular structure B The student is able to construct models that connect the movement of molecules across membranes with membrane structure and function 2.12 The student is able to use representations and models to analyze situations or solve problems qualitatively and quantitatively to investigate whether dynamic homeostasis is maintained by the active movement of molecules across membranes 1.1 2B B The student is able to explain how internal membranes and organelles contribute to cell functions 6.2 2B The student is able to use representations and models to describe differences in prokaryotic and eukaryotic cells B C The student can justify a claim made about the effect(s) on a biological system at the molecular, physiological or organismal level when given a scenario in which one or more components within a negative regulatory system is altered The student is able to connect how organisms use negative feedback to maintain their internal environments 7.2 2C C The student is able to evaluate data that show the effect(s) of changes in concentrations of key molecules on negative feedback mechanisms 2.18 The student can make predictions about how organisms use negative feedback mechanisms to maintain their internal environments 6.4 2C The student is able to make predictions about how positive feedback mechanisms amplify activities and processes in organisms based on scientific theories and models The student is able to justify that positive feedback mechanisms amplify responses in organisms 6.0 2C1 Page3

4 2.21 The student is able to justify the selection of the kind of data needed to answer scientific questions about the relevant 4.1 2C2 mechanism that organisms use to respond to changes in their external environment The student is able to refine scientific models and questions about the effect of complex biotic and abiotic interactions on 1.3 2D1 all biological systems, from cells and organisms to populations, communities and ecosystems The student is able to design a plan for collecting data to show that all biological systems (cells, organisms, populations, communities and ecosystems) are affected by complex biotic and abiotic interactions D The student is able to analyze data to identify possible patterns and relationships between a biotic or abiotic factor and a 5.1 2D1 biological system (cells, organisms, populations, communities or ecosystems 2.25 The student can construct explanations based on scientific evidence that homeostatic mechanisms reflect continuity due 6.2 2D2 to common ancestry and/or divergence due to adaptation in different environments The student is able to analyze data to identify phylogenetic patterns or relationships, showing that homeostatic 5.1 2D2 mechanisms reflect both continuity due to common ancestry and change due to evolution in different environments 2.27 The student is able to connect differences in the environment with the evolution of homeostatic mechanisms 7.1 2D The student is able to use representations or models to analyze quantitatively and qualitatively the effects of 1.4 2D3 disruptions to dynamic homeostasis in biological systems 2.29 The student can create representations and models to describe immune responses D The student can create representations or models to describe nonspecific immune defenses in plants and animals D The student can connect concepts in and across domains to show that timing and coordination of specific events are 7.2 2E1 necessary for normal development in an organism and that these events are regulated by multiple mechanisms The student is able to use a graph or diagram to analyze situations or solve problems (quantitatively or qualitatively) 1.4 2E1 that involve timing and coordination of events necessary for normal development in an organism 2.33 The student is able to justify scientific claims with scientific evidence to show that timing and coordination of several 6.1 2E1 events are necessary for normal development in an organism and that these events are regulated by multiple mechanisms 2.34 The student is able to describe the role of programmed cell death in development and differentiation, the reuse of 7.1 2E1 molecules, and the maintenance of dynamic homeostasis The student is able to design a plan for collecting data to support the scientific claim that the timing and coordination 4.2 2E2 of physiological events involve regulation 2.36 The student is able to justify scientific claims with evidence to show how timing and coordination of physiological events 7.2 2E2 involve regulation 2.37 The student is able to connect concepts that describe mechanisms that regulate the timing and coordination of 7.2 2E2 physiological events 2.38 The student is able to analyze data to support the claim that responses to information and communication of information 5.1 2E3 affect natural selection 2.39 The student is able to justify scientific claims, using evidence, to describe how timing and coordination of behavioral 6.1 2E3 events in organisms are regulated by several mechanisms The student is able to connect concepts in and across domain(s) to predict how environmental factors affect 7.2 2E3 Page4

5 responses to information and change behavior Learning Objective Sci Prac Es Knowl 3.1 The student is able to construct scientific explanations that use the structures and mechanisms of DNA and RNA to 6.5 3A1 support the claim that DNA and, in some cases, that RNA are the primary sources of heritable information The student is able to justify the selection of data from historical investigations that support the claim that DNA is the 4.1 3A1 source of heritable information 3.3 The student is able to describe representations and models that illustrate how genetic information is copied for 1.2 3A1 transmission between generations 3.4 The student is able to describe representations and models illustrating how genetic information is translated into 1.2 3A1 polypeptides 3.5 The student can justify the claim that humans can manipulate heritable information by identifying at least two commonly 6.4 3A1 used technologies 3.6 The student can predict how a change in a specific DNA or RNA sequence can result in changes in gene expression A1 3.7 The student can make predictions about natural phenomena occurring during the cell cycle 6.4 3A The student can describe the events that occur in the cell cycle 1.2 3A2 3.9 The student is able to construct an explanation, using visual representations or narratives, as to how DNA in 6.2 3A2 chromosomes is transmitted to the next generation via mitosis, or meiosis followed by fertilization 3.10 The student is able to represent the connection between meiosis and increased genetic diversity necessary for evolution 7.1 3A The student is able to evaluate evidence provided by data sets to support the claim that heritable information is passed 5.3 3A2 from one generation to another generation through mitosis, or meiosis followed by fertilization The student is able to construct a representation that connects the process of meiosis to the passage of traits from 1.1 3A3 parent to offspring The student is able to pose questions about ethical, social or medical issues surrounding human genetic disorders A The student is able to apply mathematical routines to determine Mendelian patterns of inheritance provided by data sets A The student is able to explain deviations from Mendel s model of the inheritance of traits 6.5 3A The student is able to explain how the inheritance patterns of many traits cannot be accounted for by Mendelian 6.3 3A4 genetics The student is able to describe representations of an appropriate example of inheritance patterns that cannot be 1.2 3A4 explained by Mendel s model of the inheritance of traits The student is able to describe the connection between the regulation of gene expression and observed differences 7.1 3B 1 between different kinds of organisms The student is able to describe the connection between the regulation of gene expression and observed differences 7.1 3B1 between individuals in a population 3.20 The student is able to explain how the regulation of gene expression is essential for the processes and structures that 6.2 3B1 support efficient cell function The student is able to explain how the regulation of gene expression is essential for the processes and structures that 6.2 3B1 support efficient cell function The student is able to explain how signal pathways mediate gene expression, including how this process can affect protein production B2 Page5

6 3.23 The student can use representations to describe mechanisms of the regulation of gene expression B The student is able to predict how a change in genotype, when expressed as a phenotype, provides a variation that can 6.4 3C1 be subject to natural selection The student can create a visual representation to illustrate how changes in a DNA nucleotide sequence can result in a 1.1 3C1 change in the polypeptide produced The student is able to explain the connection between genetic variations in organisms and phenotypic variations in 7.2 3C1 populations 3.27 The student is able to compare and contrast processes by which genetic variation is produced and maintained in 7.2 3C2 organisms from multiple domains 3.28 The student is able to construct an explanation of the multiple processes that increase variation within a population C The student is able to construct an explanation of how viruses introduce genetic variation in host organisms C The student is able to use representations and appropriate models to describe how viral replication introduces genetic 1.4 3C3 variation in the viral population The student is able to describe basic chemical processes for cell communication shared across evolutionary lines of descent 7.2 3D The student is able to describe basic chemical processes for cell communication shared across evolutionary lines of descent 7.2 3D The student is able to use representation(s) and appropriate models to describe features of a cell signaling pathway 1.4 3D The student is able to construct explanations of cell communication through cell-to-cell direct contact or through chemical signaling 6.2 3D D The student is able to create representation(s) that depict how cell-to-cell communication occurs by direct contact or from a distance through chemical signaling The student is able to describe a model that expresses the key elements of signal transduction pathways by which a signal is converted to a cellular response 1.5 3D The student is able to justify claims based on scientific evidence that changes in signal transduction pathways can alter cellular response 6.1 3D D The student is able to describe a model that expresses key elements to show how change in signal transduction can alter cellular response The student is able to construct an explanation of how certain drugs affect signal reception and, consequently, signal transduction pathways 6.2 3D E The student is able to analyze data that indicate how organisms exchange information in response to internal changes and external cues, and which can change behavior The student is able to create a representation that describes how organisms exchange information in response to internal changes and external cues, and which can result in changes in behavior 1.1 3E The student is able to describe how organisms exchange information in response to internal changes or environmental cues E E The student is able to construct an explanation, based on scientific theories and models, about how nervous systems detect external and internal signals, transmit and integrate information, and produce responses 3.44 The student is able to describe how nervous systems detect external and internal signals 1.2 3E The student is able to describe how nervous systems transmit information E The student is able to describe how the vertebrate brain integrates information to produce a response 1.2 3E The student is able to create a visual representation of complex nervous systems to describe/explain how these systems detect external and internal signals, transmit and integrate information, and produce responses E The student is able to create a visual representation to describe how nervous systems detect external and internal signals E The student is able to create a visual representation to describe how nervous systems transmit information 1.1 3E The student is able to create a visual representation to describe how the vertebrate brain integrates information to produce a response 1.1 3E2 Page6

7 Learning Objective Sci Prac Es Knowl 7.1 4A1 4.1 The student is able to explain the connection between the sequence and the subcomponents of a biological polymer and its properties. [See SP 7.1; Essential knowledge 4.A.1] 4.2 The student is able to refine representations and models to explain how the subcomponents of a biological polymer and their sequence determine the properties of that polymer. 4.3 The student is able to use models to predict and justify that changes in the subcomponents of a biological polymer affect the functionality of the molecule 1.3 4A1 6.1, 6.4 4A1 4.4 The student is able to make a prediction about the interactions of subcellular organelles A A2 4.5 The student is able to construct explanations based on scientific evidence as to how interactions of subcellular structures provide essential functions 4.6 The student is able to use representations and models to analyze situations qualitatively to describe how interactions of subcellular structures, which possess specialized functions, provide essential functions The student is able to refine representations to illustrate how interactions between external stimuli and gene expression result in specialization of cells, tissues and organs. 4.8 The student is able to evaluate scientific questions concerning organisms that exhibit complex properties due to the interaction of their constituent parts 1.4 4A A A3 4.9 The student is able to predict the effects of a change in a component(s) of a biological system on the functionality of an organism(s) A The student is able to refine representations and models to illustrate biocomplexity due to interactions of the constituent parts A4 1.4, 4.1 4A The student is able to justify the selection of the kind of data needed to answer scientific questions about the interaction of populations within communities The student is able to apply mathematical routines to quantities that describe communities composed of populations of organisms that interact in complex ways. [See 2.2 4A The student is able to predict the effects of a change in the community s populations on the community A A The student is able to apply mathematical routines to quantities that describe interactions among living systems and their environment, which result in the movement of matter and energy The student is able to use visual representations to analyze situations or solve problems qualitatively to illustrate how interactions among living systems and with their environment result in the movement of matter and energy 1.4 4A The student is able to predict the effects of a change of matter or energy availability on communities 6.4 4A The student is able to analyze data to identify how molecular interactions affect structure and function B B The student is able to use representations and models to analyze how cooperative interactions within organisms promote efficiency in the use of energy and matter 4.19 The student is able to use data analysis to refine observations and measurements regarding the effect of population interactions on patterns of species distribution and abundance The student is able to explain how the distribution of ecosystems changes over time by identifying large-scale events that have resulted in these changes in the past. [See 5.2 4B B The student is able to predict consequences of human actions on both local and global ecosystems 6.4 4B The student is able to construct explanations based on evidence of how variation in molecular units provides cells with a wider range of functions C The student is able to construct explanations of the influence of environmental factors on the phenotype of an organism C The student is able to predict the effects of a change in an environmental factor on the genotypic expression of the phenotype. [See 6.4 4C The student is able to use theories and models to make scientific claims and/ or predictions about the effects of variation within populations on survival and fitness 4.26 The student is able to use theories and models to make scientific claims and/ or predictions about the effects of variation within populations on survival and fitness The student is able to make scientific claims and predictions about how species diversity within an ecosystem influences ecosystem stability C C C4 Page7

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