Cross-talk. between nucleus and organelles

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1 STAZIONE ZOOLOGICA ANTON DOHRN Cross-talk between nucleus and organelles September, 2004 Stazione Zoologica Anton Dohrn Naples Italy

2 Organizing Committee Luigi Del Giudice Domenica Rita Massardo Klaus Wolf CNR Naples, Italy CNR Naples, Italy University of Aachen, Germany Advisory Committee Giorgio Bernardi Ronald Butow Cecilia Saccone Stazione Zoologica A.Dohrn Naples, Italy University of Texas, USA University of Bari, Italy Meeting Secretariat Pietro Massalin Tel: Fax:

3 PROGRAM Wednesday 15/09/2004 Arrival 20:00 Dinner at Stazione Zoologica Anthon Dohrn Thursday 16/9/2004 8:45 9:15 Introductory speeches for the participants Prof. Giorgio Bernardi President Stazione Zoologica Anton Dohrn, Naples Prof. Adriano Giannola Professor of Economics of Banking, University of Naples Federico II President Istituto Banco di Napoli Fondazione Prof. Catello Polito Professor of Molecular Genetics, University of Naples Federico II Director Institute of Genetics and Biophysics A. Buzzati-Traverso Consiglio Nazionale delle Ricerche Naples Dr. Sergio De Gregorio President Associazione Italiani nel Mondo, Naples Plenary lectures L.A. Pon (New York, NY USA) 9:15 10:05 T.D. Fox Organization and Regulation of Mitochondrial (Ithaca, NY USA) Translation 10:05-10:55 R. A. Butow Mitochondria-to-nucleus signaling: the (Dallas, TX USA) retrograde response in Saccharomyces cerevisiae 10:55 11:30 Coffee Break

4 11:30 12:20 J. Soll Control of Chloroplast Biogenesis Mixing (Muenchen Germany) the Prokaryotic and the Eukaryotic Short Communications M. Jazwinski (New Orleans, LS USA) 12:20 12:40 L.A. Pon Mitochondrial movement and inheritance in (New York, NY-USA) budding yeast 12:40 13:00 P. Thorsness Determinants of Mitochondrial DNA Stability (Laramie, WY - USA) in Yeast 13:00 13:20 R. Jensen Why do yeast cells need mitochondrial (Baltimore, MD - USA) DNA? 13:20 13:40 J. Herrmann Insertion of nuclear and mitochondrially (Muenchen - Germany) encoded proteins into the inner membrane of mitochondria by the Oxa1 translocase 14:00 15:00 Lunch P. Thorsness (Laramie, WY USA) 15:00 15:20 G. Dujardin Role of Oxa1p in the assembly of (Gif-sur-Yvette - France) mitochondrial respiratory complexes 15:20 15:40 G. Michaelis Mitochondrial Signal Peptidases in Yeast (Duesseldorf Germany)

5 15:40 16:00 E. Rayko and R. Goursot Genome topology and function: some new (Paris and Patay France) concepts 16:00 16:20 M. Jazwinski Mitochondria-Nucleus Signaling and (New Orleans, LS-USA) Genome Stability in Yeast Aging 16:20 16:40 C. Jacq Genome-wide approaches and (Paris France) mitochondria biogenesis in yeast 16:40 17:10 Coffee break CHAIRMAN : J. Herrmann (Muenchen Germany) 17:10 17:30 S. Moye-Rowley Retrograde regulation of multidrug (Iowa, IA - USA) resistance in Saccharomyces cerevisiae 17:30 17:50 K. Henze The hydrogenosome- functions of an (Duesseldorf-Germany) anaerobic cousin of mitochondria 17:50 18:10 U. Vothknecht Vipp1 and chloroplast vesicle transport: (Muenchen Germany) systems involved in the biogenesis of thylakoid membranes 18:10 18:30 J. Meurer New Regulators of Gene Expression and (Muenchen - Germany) Protein Complex Assembly in the Chloroplast 18:30 18:50 D. Leister Dissecting the crosstalk between (Cologne Germany) chloroplasts, mitochondria and the nucleus in Arabidopsis: the role of transcriptomics 20:00 Dinner

6 Friday 17/9/2004 Plenary Lectures H. Spelbrink (Tampere Finland) 9:15 10:05 C. Saccone Evolution of nuclear genes involved in (Bari - Italy) mitochondrial function 10:05-10:55 M. Zeviani Human disorders due to abnormalities of the (Milano - Italy) nucleus-mitochondrion cross-talk 10:55 11:30 Coffee Break 11:30 12:20 G. Bernardi What did we learn from the yeast (Naples Italy) mitochondrial genome about the organization and evolution of genomes? Keynote 12:20 13:10 D. Wallace Ancient Origins-Modern Disease: (Irvine, CA USA) The Mitochondrial Connection 14:00 15:00 Lunch Short Communications R. E. Jensen (Baltimore, MD-USA) 15:00 15:20 G.S. Shadel Multiple Functions for the Mitochondrial (Atlanta, GA USA) Transcription Machinery 15:20 15:40 B. Schäfer Nuclear and mitochondrial contributions to

7 (Aachen Germany) the mitochondrial RNA processing machinery: A transcriptome approach in fission yeast mitochondria 15:40 16:00 R.C. Scarpulla Control of mitochondrial transcription (Chicago, IL-USA) specificity factors (TFB1 and TFB2) by nuclear respiratory factors (NRF1 and NRF2) and PGC-1 family coactivators 16:00 16:20 K.K. Singh Mitochondrial impairment, nuclear genome (Buffalo, NY USA) instability and resistance to apoptosis 16:20 16:40 T. O Brien Nuclear MRP genes and mitochondrial (Gainesville, FL - USA) disease 16:40 17:10 Coffee break G.S. Shadel (Atlanta, GA USA) 17:10 17:30 N. Avadhani Mechanism of Mitochondria-to-Nucleus (Pennsylvania, PA-USA) Stress Signaling in Mammalian Cells and its Nuclear Gene Targets 17:30 17:50 R. Wilson "Friedreich's Ataxia, a Disease of (Philadelphia, PA-USA) Mitochondrial Dysfunction Caused by Mutations in a Nuclear Gene 17:50 18:10 M. Longley and W.C. Copeland "Mitochondrial diseases from DNA (North Carolina-USA) replication catastrophes 18:10 18:30 M. Hirano Genomic mutations in thymidine phosphorylase (New York, NY-USA) cause instability of mitochondrial DNA 18:30 18:50 H. Spelbrink Twinkle, nucleoids and mtdna (Tampere Finland) maintenance 20:00 Dinner

8 C. Luban, M. Beutel, U. Stahl & U. Schmidt H. Sembongi & I. Holt Posters Systematic identification and analysis of nuclear encoded proteins that assist splicing of mitochondrial group II introns in Saccharomyces cerevisiae Alterations in gene expression accompanying changes in mitochondrial DNA copy number L. Del Giudice, D.R. Massardo, P. Pontieri & K. Wolf Interaction between yeast mitochondrial and nuclear genomes: null alleles of RTG genes affect resistance to the alkaloid lycorine in rho 0 petites of Saccharomyces cerevisiae Saturday 18/9/2004 Invited speakers are kindly requested to confirm their participation to the following social events: - Excursions by choice to be paid by participants: a) to island Capri in the morning (8.00 a.m p.m.) b) to Pompei in the morning (8.00 a.m p.m.) c) free visit of Naples - Social evening event and Dinner with Neapolitan Performance (Offered by the Organizing Committee)

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