Metal Artifact Reduction and Dose Efficiency Improvement on Photon Counting Detector CT using an Additional Tin Filter

Size: px
Start display at page:

Download "Metal Artifact Reduction and Dose Efficiency Improvement on Photon Counting Detector CT using an Additional Tin Filter"

Transcription

1 Metal Artifact Reduction and Dose Efficiency Improvement on Photon Counting Detector CT using an Additional Tin Filter Wei Zhou, Dilbar Abdurakhimova, Kishore Rajendran, Cynthia McCollough, Shuai Leng Dept. of Radiology, Mayo Clinic, Rochester, MN

2 Disclosures This work was supported by a Bioengineering Research Partnership grant R01 EB16966 from the National Institutes of Health (NIH). CHM: Others: Research Grant Siemens Nothing to disclose

3 Introduction The prevalence of metal implants leads to more frequent presentation of metal artifacts in routine CT practice General metal artifact reduction approaches: Projection based metal artifact reduction Dual energy CT virtual monochromatic imaging (high energy) Image courtesy: Michael Bruesewitz, Mayo Clinic 3

4 Introduction PCD CT System Overview Based on a 2 nd generation DSDE CT EID: Energy Integrating Detector PCD: Photon Counting Detector 1. Kappler et al, "A research prototype system for quantum counting clinical CT". in SPIE Medical Imaging Yu et al., "Evaluation of conventional imaging performance in a research whole body CT system with a photon counting detector array." PMB (2016).

5 Introduction PCD CT System Overview PCD counts individual pulses that exceed a threshold Threshold low (TL): 20 50keV Threshold high (TH): 50 90keV TL [25, 140] kev TH [75, 140] kev 2 threshold images (TL, TH) 2 bin images (Bin1, 2) Bin1 Bin2 5

6 Introduction PCD CT System Overview TL TH TH has higher effective energy than TL Less metal artifacts in TH TH has less photons than TL More noisy in TH Bin1 Bin2 6

7 PCD CT System Additional Tin Filtration 60.5 E eff = % of photons kev 42.2 E eff = % of photons kev With additional 0.4 mm tin filtration on PCD CT: the photon beam will be pre hardened the percentage of photons will increase for TH images 7

8 Purpose To investigate the impact of additional spectral filtration on metal artifacts, image noise and radiation dose on a PCD CT system. To determine the optimal energy threshold (TH) configuration. 8

9 Methods Phantoms 3D printed spine model with pedicle screws, embedded in a 30 cm water tank 9

10 Methods Imaging Techniques on PCD CT No Additional Tin 140 kv TL = 25 kev TH = 70, 75, 80 kev 144 mas Match clinical CTDIvol mgy Data completion scan Recon with D30, 1.0/1.0 mm 0.4 mm Tin 140 kv TL = 25 kev TH = 70, 75, 80 kev 458 mas Match clinical CTDIvol mgy Data completion scan Recon with D30, 1.0/1.0 mm 10

11 Methods Analysis Artifact Quantification Define 5 artifacts region and 1 background in water region Calculate absolute CT # difference between artifacts and background regions Repeat for 5 slices Noise Average background from 5 consecutive slices 11

12 Results Tin Effects on Image Quality [25 140) kev w/o with Tin [75 140) kev w/o Tin [75 140) kev with Tin W/L = 400/40 HU 12

13 Results Tin Effects on Image Quality Less metal artifact contamination with additional Tin filtration 13

14 Results Tin Effects on Image Quality Image noise reduced from 43.8 HU to 32.3 HU for the [75, 140) kev images using a 0.4 mm Tin filter Increased percentage of photons with Tin in TH 14

15 Purpose To investigate the impact of additional spectral filtration on metal artifacts, image noise and radiation dose on a PCD CT system. To determine the optimal energy threshold (TH) configuration. 15

16 Results Optimal TH with Tin [70 140) kev [75 140) kev [80 140) kev 16

17 Results Optimal TH with Tin 37.0 HU 30.0 HU 32.3 HU 17

18 Conclusion The additional Tin filtration on the PCD CT system substantially reduced metal artifacts and increased dose efficiency [25 140] kev w/o Tin [75 140] kev w/o Tin [75 140] kev with Tin Reduce artifacts Reduce noise 18

19 Conclusion Our results suggested TH = 75 kev was the optimal threshold for the 140 kv protocol on PCD CT to balance between metal artifacts and image noise. Future study could combine tin filtration with iterative reconstruction and VMI to further reduce artifacts. 19

20

21 CT Clinical Innovation Center

22

Multi-Energy CT: Principles, Processing

Multi-Energy CT: Principles, Processing Multi-Energy CT: Principles, Processing and Clinical Applications Shuai Leng, PhD Associate Professor Department of Radiology Mayo Clinic, Rochester, MN Clinical Motivation CT number depends on x-ray attenuation

More information

Data Acquisition and Image Formation Methods for Multi Energy CT

Data Acquisition and Image Formation Methods for Multi Energy CT Data Acquisition and Image Formation Methods for Multi Energy CT Cynthia H. McCollough, PhD, DABR, FAIMBE, FAAPM, FACR Professor of Medical Physics and Biomedical Engineering Director, CT Clinical Innovation

More information

Metal Artifact Reduction with DECT

Metal Artifact Reduction with DECT Metal Artifact Reduction with DECT Daniele Marin, MD Duke University Medical Center Metal artifacts Common clinical problem ( 20%) Boas EF et al. Radiology 2011 Beam Hardening Edge Effects Scatter Metal

More information

Multi-energy CT: Future Directions. Acknowledgements. Overview 7/23/2014. Taly Gilat Schmidt, PhD. Kevin Zimmerman Franco Rupcich Steven Haworth

Multi-energy CT: Future Directions. Acknowledgements. Overview 7/23/2014. Taly Gilat Schmidt, PhD. Kevin Zimmerman Franco Rupcich Steven Haworth Multi-energy CT: Future Directions Taly Gilat Schmidt, PhD Department of Biomedical Engineering Marquette University Acknowledgements Kevin Zimmerman Franco Rupcich Steven Haworth Results in this talk:

More information

Two-Material Decomposition From a Single CT Scan Using Statistical Image Reconstruction

Two-Material Decomposition From a Single CT Scan Using Statistical Image Reconstruction / 5 Two-Material Decomposition From a Single CT Scan Using Statistical Image Reconstruction Yong Long and Jeffrey A. Fessler EECS Department James M. Balter Radiation Oncology Department The University

More information

Detector. * All clinical images are courtesy of. University, Jerusalem. Ami Altman, Ph.D., and Raz Carmi Ph.D., CT BU, PHILIPS Healthcare

Detector. * All clinical images are courtesy of. University, Jerusalem. Ami Altman, Ph.D., and Raz Carmi Ph.D., CT BU, PHILIPS Healthcare AD Dual-Energy alenerg CT Based on A Double Layer Detector * All clinical images are courtesy of Hadassah Medical Center, The Hebrew University, Jerusalem Ami Altman, Ph.D., and Raz Carmi Ph.D., CT BU,

More information

Neural Network Approach for Photon-counting Detection The First Step: PPE Correction

Neural Network Approach for Photon-counting Detection The First Step: PPE Correction Neural Network Approach for Photon-counting Detection The First Step: PPE Correction Ruibin Feng, Ph.D. Biomedical Imaging Center, CBIS/BME, RPI fengr@rpi.edu David Rundle JairiNovus Technologies Ltd.

More information

CT-PET calibration : physical principles and operating procedures F.Bonutti. Faustino Bonutti Ph.D. Medical Physics, Udine University Hospital.

CT-PET calibration : physical principles and operating procedures F.Bonutti. Faustino Bonutti Ph.D. Medical Physics, Udine University Hospital. CT-PET calibration : physical principles and operating procedures Faustino Bonutti Ph.D. Medical Physics, Udine University Hospital Topics Introduction to PET physics F-18 production β + decay and annichilation

More information

Potentials for Dual-energy kv/mv On-board Imaging and Therapeutic Applications

Potentials for Dual-energy kv/mv On-board Imaging and Therapeutic Applications Potentials for Dual-energy kv/mv On-board Imaging and Therapeutic Applications Fang-Fang Yin Department of Radiation Oncology Duke University Medical Center Acknowledgement Dr Hao Li for his excellent

More information

Applications of Low KeV Imaging in Abdomen

Applications of Low KeV Imaging in Abdomen Applications of Low KeV Imaging in Abdomen Dushyant Sahani, M.D Director of CT Associate Professor of Radiology Massachusetts General Hospital Harvard Medical School Email-dsahani@partners.org Disclosure

More information

A practical approach to the introduction of spectral imaging into a large UK acute care teaching hospital

A practical approach to the introduction of spectral imaging into a large UK acute care teaching hospital A practical approach to the introduction of spectral imaging into a large UK acute care teaching hospital Robert Loader Clinical Scientist Clinical & Radiation Physics Directorate of Healthcare Science

More information

ESTIMATION OF 90 SCATTERING COEFFICIENT IN THE SHIELDING CALCULATION OF DIAGNOSTIC X-RAY EQUIPMENT

ESTIMATION OF 90 SCATTERING COEFFICIENT IN THE SHIELDING CALCULATION OF DIAGNOSTIC X-RAY EQUIPMENT Proceedings of the Eleventh EGS4 Users' Meeting in Japan, KEK Proceedings 2003-15, p.107-113 ESTIMATION OF 90 SCATTERING COEFFICIENT IN THE SHIELDING CALCULATION OF DIAGNOSTIC X-RAY EQUIPMENT K. Noto and

More information

Comparison of Polychromatic and Monochromatic X-rays for Imaging

Comparison of Polychromatic and Monochromatic X-rays for Imaging Comparison of Polychromatic and Monochromatic X-rays for Imaging M. Hoheisel 1, P. Bernhardt 1, R. Lawaczeck 2, and H. Pietsch 2 1 Siemens AG Medical Solutions, Forchheim, Germany 2 Schering AG Imaging

More information

Electron density and effective atomic number images generated by dual energy imaging with a 320-detector CT system: A feasibility study

Electron density and effective atomic number images generated by dual energy imaging with a 320-detector CT system: A feasibility study Electron density and effective atomic number images generated by dual energy imaging with a 320-detector CT system: A feasibility study Poster No.: C-0403 Congress: ECR 2014 Type: Scientific Exhibit Authors:

More information

Carlo N. De Cecco, MD, PhD

Carlo N. De Cecco, MD, PhD New Contrast Injection Strategies in Low kv and kev Imaging Carlo N. De Cecco, MD, PhD FSCBTMR - FSCCT - FESGAR Consultant for / Research support from: Siemens Bayer Guerbet Low kv and kev imaging Rationale

More information

An experimental study of dual-energy CT imaging using synchrotron radiation

An experimental study of dual-energy CT imaging using synchrotron radiation Nuclear Science and Techniques 24 (2013) 020102 An experimental study of dual-energy CT imaging using synchrotron radiation HAO Jia 1,2 ZHANG Li 1,2 XING Yuxiang 1,2 KANG Kejun 1,2 1 Department of Engineering

More information

DUAL ENERGY of the Pancreas

DUAL ENERGY of the Pancreas DUAL ENERGY of the Pancreas Desiree E. Morgan, MD Professor and Vice Chair Clinical Research Director Human Imaging Shared Facility UAB CCC University of Alabama at Birmingham Opportunities to improve?

More information

The relationship between image noise and spatial resolution of CT scanners

The relationship between image noise and spatial resolution of CT scanners The relationship between image noise and spatial resolution of CT scanners Sue Edyvean, Nicholas Keat, Maria Lewis, Julia Barrett, Salem Sassi, David Platten ImPACT*, St George s Hospital, London *An MDA

More information

Ke Li and Guang-Hong Chen

Ke Li and Guang-Hong Chen Ke Li and Guang-Hong Chen Brief introduction of x-ray differential phase contrast (DPC) imaging Intrinsic noise relationship between DPC imaging and absorption imaging Task-based model observer studies

More information

Radionuclide Imaging MII Positron Emission Tomography (PET)

Radionuclide Imaging MII Positron Emission Tomography (PET) Radionuclide Imaging MII 3073 Positron Emission Tomography (PET) Positron (β + ) emission Positron is an electron with positive charge. Positron-emitting radionuclides are most commonly produced in cyclotron

More information

Heuijin Lim, Manwoo Lee, Jungyu Yi, Sang Koo Kang, Me Young Kim, Dong Hyeok Jeong

Heuijin Lim, Manwoo Lee, Jungyu Yi, Sang Koo Kang, Me Young Kim, Dong Hyeok Jeong Original Article PMP Progress in Medical Physics 28(2), June 2017 https://doi.org/10.14316/pmp.2017.28.2.49 pissn 2508-4445, eissn 2508-4453 Electron Energy Distribution for a Research Electron LINAC Heuijin

More information

Recent advances and future perspectives of gamma imagers for scintimammography

Recent advances and future perspectives of gamma imagers for scintimammography 3rd International Conference on Imaging Technologies in Biomedical Sciences: ITBS2005 Innovation in Nuclear and Radiological Imaging: From Basic Research to Clinical Application Milos Conference Center,

More information

Design of a virtual model of a hand-held Germanium detector and a voxelized ICRP whole body phantom: A Monte Carlo study

Design of a virtual model of a hand-held Germanium detector and a voxelized ICRP whole body phantom: A Monte Carlo study Design of a virtual model of a hand-held Germanium detector and a voxelized ICRP whole body phantom: A Monte Carlo study ASM SABBIR AHMED 1, Gary H Kramer 2, Kurt Ungar 2 1 University of Saskatchewan,

More information

Overview and Status of the Austrian Particle Therapy Facility MedAustron. Peter Urschütz

Overview and Status of the Austrian Particle Therapy Facility MedAustron. Peter Urschütz Overview and Status of the Austrian Particle Therapy Facility MedAustron Peter Urschütz MedAustron Centre for ion beam therapy and non-clinical research Treatment of 1200 patients/year in full operation

More information

X. Allen Li. Disclosure. DECT: What, how and Why Why dual-energy CT (DECT)? 7/30/2018. Improving delineation and response assessment using DECT in RT

X. Allen Li. Disclosure. DECT: What, how and Why Why dual-energy CT (DECT)? 7/30/2018. Improving delineation and response assessment using DECT in RT Improving delineation and response assessment using DECT in RT X. Allen Li Medical College of Wisconsin MO-A-DBRA-1, AAPM, July 30 th, 2018 Disclosure Research funding support: Siemens Healthineers Elekta

More information

Abdominal DECT: How to Integrate Into Your Practice

Abdominal DECT: How to Integrate Into Your Practice Abdominal DECT: How to Integrate Into Your Practice Eric Tamm, M.D. Department of Diagnostic Radiology Division of Diagnostic Imaging MD Anderson Cancer Center Houston, TX Disclosure I have no relationships

More information

MEDICAL EQUIPMENT: NUCLEAR MEDICINE. Prof. Yasser Mostafa Kadah

MEDICAL EQUIPMENT: NUCLEAR MEDICINE. Prof. Yasser Mostafa Kadah MEDICAL EQUIPMENT: NUCLEAR MEDICINE Prof. Yasser Mostafa Kadah www.k-space.org Recommended Textbook Introduction to Medical Imaging: Physics, Engineering and Clinical Applications, by Nadine Barrie Smith

More information

Production of X-rays. Radiation Safety Training for Analytical X-Ray Devices Module 9

Production of X-rays. Radiation Safety Training for Analytical X-Ray Devices Module 9 Module 9 This module presents information on what X-rays are and how they are produced. Introduction Module 9, Page 2 X-rays are a type of electromagnetic radiation. Other types of electromagnetic radiation

More information

Evaluation of Phantom Equivalent Materials in Polychromatic Diagnostic X-Ray Beam

Evaluation of Phantom Equivalent Materials in Polychromatic Diagnostic X-Ray Beam Evaluation of Phantom Equivalent Materials in Polychromatic Diagnostic X-Ray Beam Radhakrishnan B Nair 1*, Ramakrishnan G 2, Chandralingam S 3 and Kurup PGG 1 1 Apollo Speciality Hospital, Chennai, India

More information

Reducing metal artefacts and radiation dose in musculoskeletal CT imaging Wellenberg, R.H.H.

Reducing metal artefacts and radiation dose in musculoskeletal CT imaging Wellenberg, R.H.H. UvA-DARE (Digital Academic Repository) Reducing metal artefacts and radiation dose in musculoskeletal CT imaging Wellenberg, R.H.H. Link to publication Citation for published version (APA): Wellenberg,

More information

THE ACTIVE PERSONNEL DOSIMETER - APFEL ENTERPRISES SUPERHEATED DROP DETECTOR*

THE ACTIVE PERSONNEL DOSIMETER - APFEL ENTERPRISES SUPERHEATED DROP DETECTOR* SLAC-PUB-5122 Rev March 1991 w THE ACTIVE PERSONNEL DOSIMETER - APFEL ENTERPRISES SUPERHEATED DROP DETECTOR* N. E. Ipe, R. J. Donahue, and D. D. Busick Stanford Linear Accelerator Center Stanford University,

More information

AQA Physics /7408

AQA Physics /7408 AQA Physics - 7407/7408 Module 10: Medical physics You should be able to demonstrate and show your understanding of: 10.1 Physics of the eye 10.1.1 Physics of vision The eye as an optical refracting system,

More information

Problem P7. Stéphanie Ménard. Dosimetry Department Fontenay-aux FRANCE IRSN QUADOS IRSN

Problem P7. Stéphanie Ménard. Dosimetry Department Fontenay-aux FRANCE IRSN QUADOS IRSN Problem P7 Stéphanie Ménard Dosimetry Department 92262 Fontenay-aux aux-roses FRANCE What are the applications of Gamma-Ray Spectrometry in Radiological Protection and in Safety? In the environment: after

More information

Ground Calibration of X-ray CCD Detectors with Charge Injection for the X-ray Imaging Spectrometer on Astro-E2

Ground Calibration of X-ray CCD Detectors with Charge Injection for the X-ray Imaging Spectrometer on Astro-E2 Ground Calibration of X-ray CCD Detectors with Charge Injection for the X-ray Imaging Spectrometer on Astro-E2 Beverly LaMarr a, Mark Bautz a, Steve Kissel a, Gregory Prigozhin a Kiyoshi Hayashida b Takeshi

More information

Calibration of a pencil ionization chamber with and without preamplifier

Calibration of a pencil ionization chamber with and without preamplifier Calibration of a pencil ionization chamber with and without preamplifier Ana F. Maia and Linda V. E. Caldas Instituto de Pesquisas Energéticas e Nucleares Comissão Nacional de Energia Nuclear Av. Prof.

More information

What is scintigraphy? The process of obtaining an image or series of sequential images of the distribution of a radionuclide in tissues, organs, or

What is scintigraphy? The process of obtaining an image or series of sequential images of the distribution of a radionuclide in tissues, organs, or Let's remind... What is nuclear medicine? Nuclear medicine can be broadly divided into two branches "in vitro" and "in vivo" procedures. There are numerous radioisotopic "in vitro" procedures for genotyping

More information

Midterm Review. Yao Wang Polytechnic University, Brooklyn, NY 11201

Midterm Review. Yao Wang Polytechnic University, Brooklyn, NY 11201 Midterm Review Yao Wang Polytechnic University, Brooklyn, NY 11201 Based on J. L. Prince and J. M. Links, Medical maging Signals and Systems, and lecture notes by Prince. Figures are from the textbook.

More information

BI-LAYER PROTECTION AGAINST SCATTER RADIATION

BI-LAYER PROTECTION AGAINST SCATTER RADIATION BI-LAYER PROTECTION AGAINST SCATTER RADIATION An all new innovation in radiation protection core material THE STORY Kiarmor is an all new innovation in radiation protection core material, the combination

More information

Introduction to SPECT & PET TBMI02 - Medical Image Analysis 2017

Introduction to SPECT & PET TBMI02 - Medical Image Analysis 2017 Introduction to SPECT & PET TBMI02 - Medical Image Analysis 2017 Marcus Ressner, PhD, Medical Radiation Physicist, Linköping University Hospital Content What is Nuclear medicine? Basic principles of Functional

More information

Research on the Method to Obtain Effective Energy in Materials Density Test Using X-ray CT

Research on the Method to Obtain Effective Energy in Materials Density Test Using X-ray CT 18th World Conference on Nondestructive Testing, 16-20 April 2012, Durban, South Africa Research on the Method to Obtain Effective Energy in Materials Density Test Using X-ray CT Ni Peijun Zhang Weiguo

More information

HEAVY ion therapy is an advantageous modality over the

HEAVY ion therapy is an advantageous modality over the Measurement of electron density and effective atomic number using dual-energy x-ray CT T. Tsunoo, M. Torikoshi, Y. Ohno, M. Endo, M. Natsuhori, T. Kakizaki, N. Yamada, N. Ito, N. Yagi, and K. Uesugi Abstract

More information

Joint Bayesian Compressed Sensing with Prior Estimate

Joint Bayesian Compressed Sensing with Prior Estimate Joint Bayesian Compressed Sensing with Prior Estimate Berkin Bilgic 1, Tobias Kober 2,3, Gunnar Krueger 2,3, Elfar Adalsteinsson 1,4 1 Electrical Engineering and Computer Science, MIT 2 Laboratory for

More information

Introduction. X-Ray Production and Quality. Fluorescence Yield. Fluorescence X-Rays. Initiating event. Initiating event 3/18/2011

Introduction. X-Ray Production and Quality. Fluorescence Yield. Fluorescence X-Rays. Initiating event. Initiating event 3/18/2011 X-Ray Production and Quality Chapter 9 F.A. Attix, Introduction to Radiological Physics and Radiation Dosimetry Introduction Physics of x-ray generation Fluorescence x-rays Bremsstrahlung x-rays Beam quality

More information

The Generalized NEQ and Detectability Index for Tomosynthesis and Cone-Beam CT

The Generalized NEQ and Detectability Index for Tomosynthesis and Cone-Beam CT The Generalized NEQ and Detectability Inde for Tomosynthesis and Cone-Beam CT Grace J. Gang 1, Junghoon Lee 2, J. Webster Stayman 3, Daniel Tward 3,W. Zbijewski 3, Jerry L. Prince 2, and Jeffrey H. Siewerdsen

More information

Initial Studies in Proton Computed Tomography

Initial Studies in Proton Computed Tomography SCIPP Initial Studies in Proton Computed Tomography L. R. Johnson, B. Keeney, G. Ross, H. F.-W. Sadrozinski, A. Seiden, D.C. Williams, L. Zhang Santa Cruz Institute for Particle Physics, UC Santa Cruz,

More information

COMPARISON OF PERSONNEL RADIATION MONITORING DOSIMETERS DESIGNED FOR MEDICAL FIELD

COMPARISON OF PERSONNEL RADIATION MONITORING DOSIMETERS DESIGNED FOR MEDICAL FIELD COMPARISON OF PERSONNEL RADIATION MONITORING DOSIMETERS DESIGNED FOR MEDICAL FIELD Kirill SKOVORODKO, Birute GRICIENE, Milda PETKELYTE Radiation Protection Division, Vilnius University Hospital Santaros

More information

Outline. Virtual Clinical Trials. Psychophysical Discrimination of Gaussian Textures. Psychophysical Validation

Outline. Virtual Clinical Trials. Psychophysical Discrimination of Gaussian Textures. Psychophysical Validation Phantom Realism in Virtual (pre-) Clinical Trials: A Statistical Properties Perspective Craig Abbey Phantom Realism What is the goal? What can we do? Outline Statistical Properties Power spectra Virtual

More information

7/30/2018. CT Hardware Basics. X-ray Tube Physics and Dose Reduction

7/30/2018. CT Hardware Basics. X-ray Tube Physics and Dose Reduction J. Webster Stayman Advanced Imaging Algorithms and Instrumentation Lab (aiai.jhu.edu) Johns Hopkins University August 30, 018 CT Hardware Basics X-ray Tube Detector (image Credit) https://www.youtube.com/watch?v=bg0inhwarw

More information

PET. Technical aspects

PET. Technical aspects PET Technical aspects 15 N 15 O Detector 1 β+ Detector 2 e- Evolution of PET Detectors CTI/Siemens 15 N 15 O Detector block 1 β+ Detector block 2 x e- x y y location line of response Constant fraction

More information

Inversion of the Broken Ray Transform

Inversion of the Broken Ray Transform University of Central Florida Electronic Theses and Dissertations Doctoral Dissertation (Open Access) Inversion of the Broken Ray Transform 2014 Roman Krylov University of Central Florida Find similar

More information

Recent Advances of Planar Silicon APD Technology

Recent Advances of Planar Silicon APD Technology Recent Advances of Planar Silicon APD Technology M. McClish 1, R. Farrell 1, R. Myers 1, F. Olschner 2, G. Entine 1, K.S. Shah 1 1 Radiation Monitoring Devices Inc., Watertown, MA 2 Cremat Inc., Newton,

More information

Solid State LightBurst New PET Technology GE PET/CT and PET/MR

Solid State LightBurst New PET Technology GE PET/CT and PET/MR Solid State LightBurst New PET Technology GE PET/CT and PET/MR Osama Mawlawi PhD. Dept. of Imaging Physics MD Anderson Cancer Center Disclosures SIEMENS Research grant GE research grant Discovery MI LYSO

More information

X-RAY MICRO-TOMOGRAPHY OF PORE-SCALE FLOW AND TRANSPORT. University of California Davis. Dorthe Wildenschild & Annette Mortensen

X-RAY MICRO-TOMOGRAPHY OF PORE-SCALE FLOW AND TRANSPORT. University of California Davis. Dorthe Wildenschild & Annette Mortensen X-RAY MICRO-TOMOGRAPHY OF PORE-SCALE FLOW AND TRANSPORT Jan W. Hopmans University of California Davis Volker Clausnitzer Dorthe Wildenschild & Annette Mortensen ISSUES: Measurements and modeling of water

More information

Restoration of Missing Data in Limited Angle Tomography Based on Helgason- Ludwig Consistency Conditions

Restoration of Missing Data in Limited Angle Tomography Based on Helgason- Ludwig Consistency Conditions Restoration of Missing Data in Limited Angle Tomography Based on Helgason- Ludwig Consistency Conditions Yixing Huang, Oliver Taubmann, Xiaolin Huang, Guenter Lauritsch, Andreas Maier 26.01. 2017 Pattern

More information

City University of Hong Kong

City University of Hong Kong City University of Hong Kong Information on a Course offered by the Department of Physics and Materials Science with effect from Semester A in 2013 / 2014 Part I Course Title: Radiological Physics and

More information

F3-A2/F3-A3: Tensor-based formulation for Spectral Computed Tomography (CT) with novel regularization techniques

F3-A2/F3-A3: Tensor-based formulation for Spectral Computed Tomography (CT) with novel regularization techniques F3-A2/F3-A3: Tensor-based formulation for Spectral Computed Tomography (CT) with novel regularization techniques Abstract Spectral computed tomography (CT) has become possible with the development of photon

More information

Minimum Detectable and Maximum Missable Activities

Minimum Detectable and Maximum Missable Activities and Maximum Missable The HPA Approach David Williams 18 May 2005 Centre for Radiation, Chemical and Environmental Hazards Radiation Protection Division formerly the National Radiological Protection Board

More information

Experimental validation of two dual-energy CT methods for proton therapy using heterogeneous tissue samples

Experimental validation of two dual-energy CT methods for proton therapy using heterogeneous tissue samples Experimental validation of two dual-energy CT methods for proton therapy using heterogeneous tissue samples Esther B ar a) Acoustics and Ionising Radiation Team, National Physical Laboratory, Hampton Road,

More information

Georgia Institute of Technology. Radiation Detection & Protection (Day 3)

Georgia Institute of Technology. Radiation Detection & Protection (Day 3) Georgia Institute of Technology The George W. Woodruff School of Mechanical Engineering Nuclear & Radiological Engineering/Medical Physics Program Ph.D. Qualifier Exam Spring Semester 2009 Your ID Code

More information

Bases of radioisotope diagnostic methods

Bases of radioisotope diagnostic methods Medical, pharmaceutical applications of radioisotopes Bases of radioisotope diagnostic methods Dr. István Voszka Basis of application: radioisotopes have identical behavior in the organism to corresponding

More information

Recent Activities on Neutron Standardization at the Electrotechnical Laboratory

Recent Activities on Neutron Standardization at the Electrotechnical Laboratory Recent Activities on Neutron Standardization at the Electrotechnical Laboratory K. Kudo, N. Takeda, S. Koshikawa and A. Uritani Quantum Radiation Division, National Metrology Institute of Japan (NMIJ)

More information

Using Prompt gamma ray emission to address uncertainties in proton therapy

Using Prompt gamma ray emission to address uncertainties in proton therapy Using Prompt gamma ray emission to address uncertainties in proton therapy Jerimy C. Polf, PhD, DABR Department of Radia9on Oncology University of Maryland School of Medicine AAPM 2013 Disclosures and

More information

The FastScan whole body counter: efficiency as a function of BOMAB phantom size and energy modelled by MCNP

The FastScan whole body counter: efficiency as a function of BOMAB phantom size and energy modelled by MCNP The FastScan whole body counter: efficiency as a function of BOMAB phantom size and energy modelled by MCNP Gary H. Kramer and Jeannie Fung Human Monitoring Laboratory, Radiation Protection Bureau, 775

More information

Outline. Indrin J. Chetty, AAPM 2006 Monte Carlo CE course. Indrin J. Chetty Henry Ford Hospital. David W. O. Rogers Carleton University

Outline. Indrin J. Chetty, AAPM 2006 Monte Carlo CE course. Indrin J. Chetty Henry Ford Hospital. David W. O. Rogers Carleton University AAPM Task Group Report No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning Indrin J. Chetty Henry Ford Hospital David W. O.

More information

Summer Students lectures

Summer Students lectures Summer Students lectures XRF: X-ray fluorescence spectrometry Matthias Alfeld XRF: X-ray fluorescence spectrometry Hamburg, 13.08.13 > What is XRF? X-Ray Fluorescence spectrometry > What can it do? Detect

More information

Ringhals AB. Routines for whole body counting at Ringhals NPP

Ringhals AB. Routines for whole body counting at Ringhals NPP Routines for whole body counting at Ringhals NPP Structure Equipment - Quick Scan - Whole body counter Marie Carlson M.Sc. Radiology and Dosimetry Radiation Physicist and deputy RP Controller Routines

More information

Proton stopping power and range calculation using effective atom number and effective electron density from dual energy CT

Proton stopping power and range calculation using effective atom number and effective electron density from dual energy CT Proton stopping power and range calculation using effective atom number and effective electron density from dual energy CT Bachelor thesis applied physics Bert Bekker Date: 11-05- 2015 Supervisors: Emiel

More information

Latest developments in PET verification of proton therapy

Latest developments in PET verification of proton therapy Latest developments in PET verification of proton therapy Katia Parodi, Ph.D. Heidelberg Ion Therapy Centre, Heidelberg, Germany Previously: Massachusetts General Hospital and Harvard Medical School, Boston,

More information

MT Electron microscopy Scanning electron microscopy and electron probe microanalysis

MT Electron microscopy Scanning electron microscopy and electron probe microanalysis MT-0.6026 Electron microscopy Scanning electron microscopy and electron probe microanalysis Eero Haimi Research Manager Outline 1. Introduction Basics of scanning electron microscopy (SEM) and electron

More information

Silicon Drift Detectors: Understanding the Advantages for EDS Microanalysis. Patrick Camus, PhD Applications Scientist March 18, 2010

Silicon Drift Detectors: Understanding the Advantages for EDS Microanalysis. Patrick Camus, PhD Applications Scientist March 18, 2010 Silicon Drift Detectors: Understanding the Advantages for EDS Microanalysis Patrick Camus, PhD Applications Scientist March 18, 2010 EDS Detector Requirements Detect whole energy range of x-rays 50 ev

More information

1-D Fourier Transform Pairs

1-D Fourier Transform Pairs 1-D Fourier Transform Pairs The concept of the PSF is most easily explained by considering a very small point source being placed in the imaging field-of-view The relationship between the image, I, and

More information

A Brief Introduction to Medical Imaging. Outline

A Brief Introduction to Medical Imaging. Outline A Brief Introduction to Medical Imaging Outline General Goals Linear Imaging Systems An Example, The Pin Hole Camera Radiations and Their Interactions with Matter Coherent vs. Incoherent Imaging Length

More information

PHI. Scanning XPS Microprobe

PHI. Scanning XPS Microprobe PHI Scanning XPS Microprobe Unique Scanning XPS Microprobe X-ray photoelectron spectroscopy (XPS/ESA) is the most widely used surface analysis technique and has many well established industrial and research

More information

Chapter 2 PET Imaging Basics

Chapter 2 PET Imaging Basics Chapter 2 PET Imaging Basics Timothy G. Turkington PET Radiotracers Positron emission tomography (PET) imaging is the injection (or inhalation) of a substance containing a positron emitter, the subsequent

More information

Ion- and proton-beams: Experience with Monte Carlo Simulation

Ion- and proton-beams: Experience with Monte Carlo Simulation Ion- and proton-beams: Experience with Monte Carlo Simulation Katia Parodi, Ph.D. Heidelberg Ion Therapy Centre, Heidelberg, Germany (Previously: Massachusetts General Hospital, Boston, USA) Workshop on

More information

Konzepte zur Charakterisierung klinischer CT-Systeme unter Einbeziehung von Bildqualität und Dosis

Konzepte zur Charakterisierung klinischer CT-Systeme unter Einbeziehung von Bildqualität und Dosis Konzepte zur Charakterisierung klinischer CT-Systeme unter Einbeziehung von Bildqualität und Dosis Characterization of clinical CT systems using a dose efficiency index (DEI) Aktenzeichen / FKZ : BfS AG-F

More information

A FISTA-like scheme to accelerate GISTA?

A FISTA-like scheme to accelerate GISTA? A FISTA-like scheme to accelerate GISTA? C. Cloquet 1, I. Loris 2, C. Verhoeven 2 and M. Defrise 1 1 Dept. of Nuclear Medicine, Vrije Universiteit Brussel 2 Dept. of Mathematics, Université Libre de Bruxelles

More information

Nuclear Medicine Intro & Physics from Medical Imaging Signals and Systems, Chapter 7, by Prince and Links

Nuclear Medicine Intro & Physics from Medical Imaging Signals and Systems, Chapter 7, by Prince and Links Nuclear Medicine Intro & Physics from Medical Imaging Signals and Systems, Chapter 7, by Prince and Links NM - introduction Relies on EMISSION of photons from body (versus transmission of photons through

More information

Differential Absorption Analysis of Nonmagnetic Material in the Phantom using Dual CT

Differential Absorption Analysis of Nonmagnetic Material in the Phantom using Dual CT Journal of Magnetics 21(2), 286-292 (2016) ISSN (Print) 1226-1750 ISSN (Online) 2233-6656 http://dx.doi.org/10.4283/jmag.2016.21.2.286 Differential Absorption Analysis of Nonmagnetic Material in the Phantom

More information

Development of XCT & BLT

Development of XCT & BLT Development of XCT & BLT Ge Wang, Wenxiang Cong, Hengyong Yu Biomedical Imaging Division VT-WFU School of Biomedical Engineering & Sciences Virginia Tech, Blacksburg, Virginia, USA http://www.imaging.sbes.vt.edu

More information

Micro Computed Tomography Based Quantification of Pore Size in Electron Beam Melted Titanium Biomaterials

Micro Computed Tomography Based Quantification of Pore Size in Electron Beam Melted Titanium Biomaterials Micro Computed Tomography Based Quantification of Pore Size in Electron Beam Melted Titanium Biomaterials SJ Tredinnick* JG Chase ** *NZi3 National ICT Innovation Institute, University of Canterbury, Christchurch,

More information

Photon Detection. Array of Photon Detectors. Response Function. Photon Detection. The goal is a simple model for photon detection.

Photon Detection. Array of Photon Detectors. Response Function. Photon Detection. The goal is a simple model for photon detection. Photon Detection The goal is a simple model for photon detection. The detector model will have an onset threshold and a saturation level. Photon Detection The photon stream will be treated as a Poisson

More information

University of Cyprus. Reflectance and Diffuse Spectroscopy

University of Cyprus. Reflectance and Diffuse Spectroscopy University of Cyprus Biomedical Imaging and Applied Optics Reflectance and Diffuse Spectroscopy Spectroscopy What is it? from the Greek: spectro = color + scope = look at or observe = measuring/recording

More information

Spectral Filtering for Improving Quality of Material Discrimination Using Dual Energy X-rays

Spectral Filtering for Improving Quality of Material Discrimination Using Dual Energy X-rays Spectral Filtering for Improving Quality of Material Discrimination Using Dual X-rays Y. M. Gil, Y. S. Lee, M. H. Cho, and W. Namgung POSTECH, PAL POSTECH Abstract The well-known dual energy method of

More information

Beam Test Result for a Prototype PbWO 4 Calorimeter. by Matthew Reece

Beam Test Result for a Prototype PbWO 4 Calorimeter. by Matthew Reece Beam Test Result for a Prototype PbWO 4 Calorimeter by Matthew Reece PrimEx experiment The goal of the PrimEx collaboration is to determine the lifetime of the π 0 particle with greater accuracy than ever

More information

DEVIL PHYSICS THE BADDEST CLASS ON CAMPUS IB PHYSICS

DEVIL PHYSICS THE BADDEST CLASS ON CAMPUS IB PHYSICS DEVIL PHYSICS THE BADDEST CLASS ON CAMPUS IB PHYSICS TSOKOS OPTION I-2 MEDICAL IMAGING Reading Activity Answers IB Assessment Statements Option I-2, Medical Imaging: X-Rays I.2.1. I.2.2. I.2.3. Define

More information

Positron Emission Tomography

Positron Emission Tomography Positron Emission Tomography Presenter: Difei Wang June,2018 Universität Bonn Contents 2 / 24 1 2 3 4 Positron emission Detected events Detectors and configuration Data acquisition Positron emission Positron

More information

Analytical Chemistry II

Analytical Chemistry II Analytical Chemistry II L4: Signal processing (selected slides) Computers in analytical chemistry Data acquisition Printing final results Data processing Data storage Graphical display https://www.creativecontrast.com/formal-revolution-of-computer.html

More information

Determining how uncertainties in optical properties affect light dose calculations

Determining how uncertainties in optical properties affect light dose calculations Determining how uncertainties in optical properties affect light dose calculations Julia Sandell 1, Jarod Finlay, Timothy Zhu 1 Department of Physics, University of Pennsylvania Radiation Oncology, Hospital

More information

ABSOLUTE AIR-KERMA MEASUREMENT IN A SYNCHROTRON LIGHT BEAM BY IONIZATION FREE-AIR CHAMBER

ABSOLUTE AIR-KERMA MEASUREMENT IN A SYNCHROTRON LIGHT BEAM BY IONIZATION FREE-AIR CHAMBER ABSOLUTE AIR-KERMA MEASUREMENT IN A SYNCHROTRON LIGHT BEAM BY IONIZATION FREE-AIR CHAMBER M. Bovi (1), R.F. Laitano (1), M. Pimpinella (1), M. P. Toni (1), K. Casarin(2), E. Quai(2), G. Tromba(2), A. Vascotto(2),

More information

Technical University of Denmark

Technical University of Denmark Technical University of Denmark Page 1 of 10 pages Written test, 12 December 2012 Course name: Introduction to medical imaging Course no. 31540 Aids allowed: None. Pocket calculator not allowed "Weighting":

More information

Optimization of microionization chambers for small-field reference dosimetry

Optimization of microionization chambers for small-field reference dosimetry Optimization of microionization chambers for small-field reference dosimetry Jessica R. Snow University of Wisconsin-Madison Department of Medical Physics Medical Radiation Research Center NCCAAPM Fall

More information

Applications of MCBEND

Applications of MCBEND Serco Assurance Applications of MCBEND Presentation to NPL Workshop on Monte Carlo codes by Pat Cowan The ANSWERS Software Service Serco Assurance Overview The MCBEND Code Traditional Applications Industrial

More information

The Photon Concept. Modern Physics [2] How are x-rays produced? Gamma rays. X-ray and gamma ray photons. X-rays & gamma rays How lasers work

The Photon Concept. Modern Physics [2] How are x-rays produced? Gamma rays. X-ray and gamma ray photons. X-rays & gamma rays How lasers work Modern Physics [2] X-rays & gamma rays How lasers work Medical applications of lasers Applications of high power lasers Medical imaging techniques CAT scans MRI s The Photon Concept a beam of light waves

More information

Procesamiento de Imágenes y Bioseñales

Procesamiento de Imágenes y Bioseñales Procesamiento de Imágenes y Bioseñales Dr. Víctor Castañeda Agenda Physical basis of X-ray- CT, NMR, Ultrasound, Nuclear Medicine Sensors (cameras, gamma probes, microphone) Computational Tomography (CT)

More information

Radioactive Decedents What is the risk?

Radioactive Decedents What is the risk? Radioactive Decedents What is the risk? Glenn M. Sturchio, PhD, CHP Radiation Safety Officer Alan Crutchfield Clinical Research Intern ICCFA Annual Convention & Expo Nashville, TN 08 April 2017 2017 MFMER

More information

Comparison between TG-51 and TRS-398: Electron Contamination Effect on Photon Beam Quality Specification.

Comparison between TG-51 and TRS-398: Electron Contamination Effect on Photon Beam Quality Specification. Comparison between TG-51 and TRS-398: Electron Contamination Effect on Photon Beam Quality Specification. Antonio Lopez Medina, Antonio Teijeiro, Daniela Medal, Francisco Salvador, Julio Vazquez, Manuel

More information

Long pulse and high power density H - ion beam accelerations for ITER - Achievement for 60 s acceleration of 1 MeV beam in QST-

Long pulse and high power density H - ion beam accelerations for ITER - Achievement for 60 s acceleration of 1 MeV beam in QST- NIBS2016 12-16 September 2016 St. Ann s College, Oxford, UK Long pulse and high power density H - ion beam accelerations for ITER - Achievement for 60 s acceleration of 1 MeV beam in QST- N.Umeda, J. Hiratsuka,

More information

Quality Assurance. Purity control. Polycrystalline Ingots

Quality Assurance. Purity control. Polycrystalline Ingots Quality Assurance Purity control Polycrystalline Ingots 1 Gamma Spectrometry Nuclide Identification Detection of Impurity Traces 1.1 Nuclides Notation: Atomic Mass Atomic Number Element Neutron Atomic

More information

1. Which of the following statements is true about Bremsstrahlung and Characteristic Radiation?

1. Which of the following statements is true about Bremsstrahlung and Characteristic Radiation? BioE 1330 - Review Chapters 4, 5, and 6 (X-ray and CT) 9/27/2018 Instructions: On the Answer Sheet, enter your 2-digit ID number (with a leading 0 if needed) in the boxes of the ID section. Fill in the

More information