NATIONAL SENIOR CERTIFICATE GRADE 12

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1 NTIONL SENIOR ERTIFITE GRE 12 LIFE SIENES P1 VERSION 1 (NEW ONTENT) FOR FULL-TIME NITES FERURY/MRH 2013 MRKS: 150 TIME: 2½ hours This question paper consists of 16 pages.

2 Life Sciences/P1 (Version 1) (Full-time) 2 E/Feb. Mar INSTRUTIONS N INFORMTION Read the following instructions carefully before answering the questions nswer LL the questions. Write LL the answers in your NSWER OOK. Start the answers to each question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. LL drawings should be done in pencil and labelled in blue or black ink. raw diagrams or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. o NOT use graph paper. You must use a non-programmable calculator, protractor and a compass, where necessary. Write neatly and legibly.

3 Life Sciences/P1 (Version 1) (Full-time) 3 E/Feb. Mar SETION QUESTION Various options are provided as possible answers to the following questions. hoose the correct answer and write only the letter ( to ) next to the question number (1.1.1 to ) in the NSWER OOK, for example Which ONE of the following is the best definition of a species? population of similar animals which can interbreed population of organisms which breed to produce fertile offspring community of organisms which can interbreed population of organisms with similar characteristics What causes the genetic disorder where some males have the sex chromosomes XXY? sex-linked recessive allele Non-disjunction of chromosomes during meiosis Two sperm cells fertilise one ovum rossing-over during meiosis The chromosome complement of a human individual who inherits an X chromosome from the father, is and XX. 44 and XY. 46 and XX. 46 and XY Which ONE of the following is an example of artificial selection? T resistance in mosquitoes The development of different species of tortoise from a common ancestor The decreasing effect of antibiotics on bacteria reeding dairy cattle to increase milk production

4 Life Sciences/P1 (Version 1) (Full-time) 4 E/Feb. Mar Studies have shown that the number of dark moths in a woodland area next to an industrial area is related to the air pollution levels in the atmosphere. When the levels of pollution increase, trees become black from the smoke. Moths are eaten by birds in this area. Which ONE of the following best describes what would happen to the number of dark moths when air pollution levels change? IR POLLUTION LEVELS NUMER OF RK MOTHS Increase Remain the same ecrease Increase Increase ecrease ecrease ecrease What percentage of adenine bases is present in a N molecule with bases, if 400 of the bases are cytosine? 20% 30% 40% 60% The diagram below shows changes in cell mass and N mass during two cell cycles. Increase in cell mass (arbitrary units) cell mass N mass Time (hours) Increase in N mass per nucleus (arbitrary units) It can be concluded from the graph that during the cell cycle... the interphase is the longest phase. the cell is dividing between 24 and 36 hours. replication takes place between 0 and 12 hours. cytokinesis takes place at 12 and 36 hours.

5 Life Sciences/P1 (Version 1) (Full-time) 5 E/Feb. Mar Two parents both have blood group. Their child has blood group O. What is the best explanation for this pattern of inheritance? The child has inherited the blood group directly from a grandparent. The parents are homozygous for the blood group alleles. The parents are heterozygous for the blood group alleles. There has been a mutation in the blood group alleles The result of profiling various N samples in a criminal investigation is shown below. Key: 1 lood sample of victim 2 lood sample of suspect X 3 lood sample of suspect Y 4 First sample of N from the crime scene 5 Second sample of N from the crime scene Which conclusion about the crime could the N analyst draw? Only suspect X was involved. Only suspect Y was involved. Suspects X and Y were both involved. Neither suspect X nor Y was involved The table below shows some genotypes and phenotypes associated with a form of anaemia. GENOTYPE Hb Hb Hb Hb S Hb S Hb S PHENOTYPE Unaffected Partial sickle-cell anaemia Severe sickle-cell anaemia person who has partial sickle-cell anaemia and an unaffected person have a child together. What are the chances of the child having severe sickle-cell anaemia? 100% 50% 25% 0% (10 x 2) (20)

6 Life Sciences/P1 (Version 1) (Full-time) 6 E/Feb. Mar Give the correct biological term for each of the following descriptions. Write only the term next to the question number (1.2.1 to 1.2.7) in the NSWER OOK The linking of the present-day distribution of organisms with the past movements of continental plates The elimination of a species from the Earth point where the exchange of genetic material occurs during crossing-over The stage in the process of the formation of a protein determined by the codons in the mrn The type of inheritance which has a range of intermediate phenotypes for a particular trait n inherited disorder in which blood fails to clot properly The position of a gene in a chromosome (7) 1.3 Indicate whether each of the statements in OLUMN I applies to ONLY, ONLY, OTH N or NONE of the items in OLUMN II. Write only, only, both and, or none next to the question number (1.3.1 to 1.3.8) in the NSWER OOK. OLUMN I OLUMN II iscovered the double helical : Francis rick structure of N : James Watson process which can detect mutant : Genetic counselling genes in an individual : Genetic testing The breeding of organisms over : loning many generations in order to achieve : rtificial selection a desirable phenotype Introduces variation within a species : Random mating : Mutation n advantage of polyploidy in : Increase in the size of agriculture fruit : Increase in the size of flowers The type of cell division that takes : Mitosis place in angiosperm plants : Meiosis Influences the inheritance of blood : odominance groups onds that holds amino acids together in a protein molecule : Multiple alleles : Hydrogen bonds : Peptide bonds (8 x 2) (16)

7 Life Sciences/P1 (Version 1) (Full-time) 7 E/Feb. Mar The pedigree diagram below traces the inheritance of vestigial (reduced in size) and normal wing characteristics in fruit flies. Study the diagram and answer the questions that follow. E F G H I J Vestigial female fruit fly Vestigial male fruit fly Normal male fruit fly Normal female fruit fly State the dominant wing characteristic of the flies used in these crosses. Use the letters G and g and write down the genotype of the following: (a) (b) J If fruit fly was crossed with a male having vestigial wings, what would be the possible genotype(s) of the offspring? (4) (7) TOTL SETION : 50

8 Life Sciences/P1 (Version 1) (Full-time) 8 E/Feb. Mar SETION QUESTION The diagram below shows part of a N molecule in a nucleus just before cell division. G KEY: G - adenine - guanine T - thymine T - cytosine 1 T G T T Identify the parts labelled: (a) (b) Identify the nitrogenous bases labelled: (a) (b) Explain why the diagram above represents replication and not transcription. (6)

9 Life Sciences/P1 (Version 1) (Full-time) 9 E/Feb. Mar rare form of rickets in humans is caused by a sex-linked dominant allele (R) which is carried on the X-chromosome. n affected female, whose father was unaffected, married an unaffected male etermine the possible genotypes and phenotypes of their offspring by representing a genetic cross. What is the percentage chance that they will have a child who is an unaffected male? Explain why this disorder, although it is sex-linked, does NOT affect males only. This genetic disorder is caused by a gene mutation in which the N triplet G is altered to TG. (6) (a) (b) Name this type of mutation. escribe how the type of mutation mentioned in QUESTION 2.2.4(a) will affect the structure of the protein it codes for Give TWO reasons why this couple should undergo genetic counselling before having children. (15) 2.3 Ribonuclease is an enzyme made up of 127 amino acids What is the minimum number of N bases needed to code for amino acids of this enzyme? The sequence of N bases coding for seven amino acids in the enzyme ribonuclease is: GTT T T TT TT TT TT The number of each type of amino acid coded for by this sequence of N bases is shown in the table below. MINO I NUMER OF MINO IS PRESENT rg 3 Met 2 Gly 1 sn 1 The first amino acid in this enzyme is Gly which is coded for by GTT in N. Use the N base sequence and the table above to work out the sequence of the remaining amino acids in this part of the enzyme. (3) (4)

10 Life Sciences/P1 (Version 1) (Full-time) 10 E/Feb. Mar Study the diagrams below representing various phases of meiosis in an organism. IGRM IGRM IGRM Which diagram (, or ) represents meiosis I? Suggest why the chromosomes in diagram will be genetically different from that of the parent cell at the beginning of meiosis. How many chromosomes will each daughter cell have at the end of this cell division? Give TWO reasons why this type of cell division is important. (5) [30]

11 Life Sciences/P1 (Version 1) (Full-time) 11 E/Feb. Mar QUESTION Professor Lee erger and his colleagues studied the fossils they found in a cave at the radle of Humankind. The skeletons from the cave are ranked amongst the most complete finds to date. The adult female, ustralopithecus sediba, was remarkably well preserved and some of the following characteristics were identified: Some characteristics of ustralopithecus sediba: small brain size ipedal Smaller canines Projecting nose Small body size [dapted from 'Part pe Part Human', Josh Fischmann, National Geographic, ugust 2011] Write down THREE characteristics from the list above that also apply to the Homo species. State TWO advantages of. sediba being bipedal. Professor erger called ustralopithecus sediba a transitional fossil. Using the information in the list above, explain why he called. sediba a species in transition. (3) (7)

12 Life Sciences/P1 (Version 1) (Full-time) 12 E/Feb. Mar Study the table below, which indicates some of the hominid fossils found in the world and answer the questions that follow. SPEIES REGION WHERE IT WS FOUN PERIO OF EXISTENE (WHEN IT LIVE) ustralopithecus afarensis Eastern frica 3,4 2,8 mya ustralopithecus africanus Southern frica 2,1 2,8 mya ustralopithecus sediba Southern frica 2,0 1,9 mya Homo habilis Sub-Saharan (frica) 2,3 1,4 mya Homo erectus frica, Europe, sia 1,5 0,2 mya Homo heidelbergensis Europe, hina 0,6 0,35 mya Homo neanderthalensis Europe, Western sia 0,35 0,03 mya Homo sapiens Worldwide 0,2 mya present [dapted from 'The Evolutionary Road', Jamie Shreeve, National Geographic, July 2010] Explain why the information in the table supports the 'Out of frica' hypothesis. If a fossil of ustralopithecus afarensis, dated 3,2 mya, is found in sia, explain the implications for the 'Out of frica' hypothesis. escribe TWO genetic lines of evidence that support the 'Out of frica' hypothesis. (3) (4) (9)

13 Life Sciences/P1 (Version 1) (Full-time) 13 E/Feb. Mar Study the analogous and homologous structures below, which can be used as evidence for evolution and answer the questions that follow. Forelimb of a bat Forelimb of a human Insect wing Examples of homologous and analogous structures Identify TWO structures in the diagram that are: (a) (b) nalogous Homologous escribe how the homologous structures named in QUESTION 3.3.1(b) give evidence for evolution. (6)

14 Life Sciences/P1 (Version 1) (Full-time) 14 E/Feb. Mar The diagram below shows five closely related species of finches found on the mainland and on four nearby islands. Mainland Island 1 Island 3 Island 2 Island 4 losely related species of finches found on the mainland and on four nearby islands escribe how the different species on the four islands evolved over many generations from the original ancestor on the mainland. (8) [30] TOTL SETION : 60

15 Life Sciences/P1 (Version 1) (Full-time) 15 E/Feb. Mar SETION QUESTION group of learners investigated the frequency of dominant and recessive traits in their school. Their hypothesis was: There will be more learners with dominant traits than learners with recessive traits. The traits below were investigated in 200 learners: OMINNT TRIT Unattached earlobe Rolled tongue ent little finger REESSIVE TRIT ttached earlobe Unrolled tongue Straight little finger The results below were obtained during the investigation. NUMER OF LERNERS TRIT OMINNT REESSIVE Earlobe Tongue Little finger Show the results for each trait above as bar graphs on the same system of axes. Explain why age need NOT be controlled in this investigation. State ONE way in which the learners ensured reliable results. State any TWO planning steps that the learners had to consider before conducting the investigation. Will the learners accept or reject their hypothesis? Explain your answer to QUESTION (8) (16)

16 Life Sciences/P1 (Version 1) (Full-time) 16 E/Feb. Mar In mosquitoes there is a gene locus which has alleles involved in resistance to T, a well-known insecticide. The graph below shows the number of mosquitoes and their genotypes collected from 1965 when T was first used, until 1970, two years after the spraying of T stopped. Number of mosquitoes Rr rr 10 0 RR Spraying started Spraying stopped Years How many alleles are involved in the trait for resistance in mosquitoes? State the genotype for resistance to T. Which genotype appeared most frequently in the population in 1970? Which genotype's chances of survival were reduced after the spraying of T was stopped in 1968? (4) 4.3 harles arwin and Jean aptiste de Lamarck had different ideas to explain evolution. escribe how each of them would have explained the evolution of the long necks of giraffes. Justify whose idea is more acceptable in the science community today. ontent: Synthesis: (17) (3) (20) NOTE: NO marks will be awarded for answers in the form of flow charts or diagrams. TOTL SETION : GRN TOTL:

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