3 rd Nano-Science Center Winter School 29/1 4/2 2008, Maria Alm, Austria

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1 3 rd Nano-Science Center Winter School 29/1 4/2 2008, Maria Alm, Austria Motivation: Following the last years tremendous success we welcome you to the 3 rd annual Nano-Science Winter School. The winter schools have succeeded in generating an environment of collaboration and solidarity within the center; sprouting friendships and scientific achievement over group boundaries. The previous year s winter schools have been focused on introducing the research focus of the different research groups in the center, creating a common language and understanding; this year will be different. In two workshop sessions we will use our joined efforts to startup the new EU-project: SINGLE and to meet the challenges at hand in project throughout the Nano-Science Center. For the plenary lectures external speakers have been invited to inspire our work and bring in an expertise we do not usually have available in our research. Keynote lectures: Thomas Tschentscher Dynamic processes studied by X-Ray scattering Herre van der Zant Electron transport in nanosystems Lise Arleth Scattering in nanoscience Rikke Bøyesen Recruitment of nanoscience students Workshops: Center for Molecular Movies: The structure of materials is an important key to understanding the relationship between synthesis and processing of the materials and their functionalities. However, the functionality of materials often involve that they - at least briefly - change the local arrangement of their constituent atoms and molecules, and hence their structure. In this workshop we will review the present status of the techniques and methods for investigating transient structures of materials in the Centre, as well as discuss new ideas for photo- and electrically excitable materials. We will have tutorials on predicting Structure-Property relationships, Photochemistry, Crystallography, and methods for data analysis followed by discussion of their applications. In the last part of the workshop, we will form working groups with the goal to provide the springboards for the next generation of research projects in. SINGLE: This purpose of this workshop is to start up the EU collaborative project SINGLE; a study of the single molecules and single molecule/electrode interfaces. The workshop will be attended by all the collaborators from the SINGLE project, giving a broad scope on a single topic. In the workshop practical issues will touched briefly, but the main focus is the science of single molecules in two or three terminal devices.

2 NanoWires: The workshop will cover two main projects resulting from strong collaborations between the BioNano laboratory and the group on Nanoscale Quantum Electronics: (1) Interfacing nanorods and mammalian cells for monitoring cellular events and (2) development of label free biosensors using Nanowire-Field Effect Transistors (Bio-FET). Single Enzymes: Single enzymes experiments are the only way to precisely quantify the catalytic behavior of the enzymes. Aspects such as time dependent activity fluctuations, otherwise masked in ensemble average measurements, have been successfully resolved by these experiments. In this session a variety of methods utilized for measuring the real time kinetics of single hydrolytic enzymes are discussed. As demonstrated enzymes can adopt a variety of inter-converting conformations each one of them exhibiting different activity. The effect of the microenvironment on their oscillating behavior is in depth studied and models are proposed successfully interpreting the results. Program: Tuesday 29/ :30 Arrival 20:00 21:00 Thomas Bjørnholm Welcome 21:00 21:30 Group presentation with 3 min. poster presentations: Center for Molecular Movies

3 Wednesday 30/1-08 SINGLE Chair: T. Bjørnholm 9:00 10:30 Project overview: Thomas Bjørnholm Scientific challenges Poul Petersen Administrative issues 11:00 12:30 Jerome Cornill/Victor Geskin Presentation from MONS Chair: M. Meedom Nielsen 9:00 10:30 Scientific Outlook : Results & Outlook Morten Christensen Structural dynamics in solution Henrik Lemke Structural dynamics in thin films of organic semiconducters 11:00 12:30 Instrumentation and methods Dmitry Khakhulin Laser driven X-ray Diode Simon O. Mariager Femtoslicing sources Thomas N. Nielsen Fast detectors and electrical excitable systems Beamtime planning/application 17:00 18:00 Workshop Group Discussion 20:00 21:00 Herre van der Zant Electron transport in nanosystems 21:00 21:30 Group presentation with 3 min. poster presentations: NanoGeoScience

4 Thursday 31/1-08 SINGLE Chair: T. Bjørnholm Chair: M. Meedom Nielsen 9:00 10:30 Herre van der Zant/Edgar 9:00 10:30 Tutorial: Osorio Jerome Cornill Presentation from Delft The relationship between structure and charge transport properties 11:00 12:00 Heike Riel of materials Presentation from IBM Chair: M. Christensen 11:00 12:30 Tutorial Kristine Kilså Photophysics & photochemistry 20:00 21:00 Rikke Bøyesen Recruitment of nanoscience students 21:00 21:30 Group presentation with 3 min. poster presentations: NanoChemistry

5 Friday 1/2-08 SINGLE Chair: T. Bjørnholm 9:00 9:30 Presentation from Chalmers Andrey Danilov Progress on SET Chair: D. Khakhulin 9:00 9:45 Emil Makovicky Introduction to experimental X-ray crystallography experiments at Chalmers 9:30 9:50 Per Hedegaard Chair: Henrik Lemke C60 quantum switch 9:45 10:10 Fredrik Westerlund 9:50 10:10 Gören Wendin Structure and optical Functional molecular electronic devices - what are relevant problems for theory? 10:10 10:25 Thomas Löfwander Graphene 10:25 10:40 Zeljko Crljen Molecular wires in nanogaps properties of fluorescent thin films 10:30 11:30 Thomas Just Sørensen/Klaus Bechgaard Relation between structure and optical properties of molecules & Novel systems of interest to timeresolved X-ray scattering 11:30 12:00 Thomas Bjørnholm 11:00 11:35 Presentation from Cph Morgens Brøndsted/Kristine 12:00 12:30 Formation of 2-4 project Kilså groups to explore the best ideas from the Design, synthesis and last two days molecular properties of new test molecules 11:35 11:50 Kasper Moth Project group discussion Self-assembly of gaps using gold nano rods 11:50 12:10 Kristen Kaasbjerg Hückel calculations of OPVs in nano gaps 12:10 12:30 Jens Paaske Modeling renormalization effects in single molecule and CNT transistors 17:00 18:00 Workshop Group Discussion 20:00 21:00 Lise Arleth Scattering in nanoscience

6 21:00 21:30 Group presentation with 3 min. poster presentations: NanoBio

7 Saturday 2/2-08 Single Enzymes Chair: N. Hatzakis Chair: K. Haldrup 9:00 9:20 Nikos Hatzakis: 9:00 10:30 Per Hedegaard Single Enzymes Studies on Lipase Activity Data analysis and parameter determination 9:40 10:20 Li Wei Effects of Environment on Conformational Fluctuations of Lipases at a single molecule level Chair: M. Meedom Nielsen 10:55 11:20 Kristoffer Haldrup "Analysis of time-resolved solution scattering Data" 10:20 10:40 Coffee break 11:20 11:45 Andreas Kring "MD simulations" 10:40 11:30 Thomas Bjørnholm Activity Studies of Single Phospholipase Molecules 11:30 12:10 Andreas Kunding 11:45-12:30 The project groups discuss and each group write a few bullets on their present ideas. Enzyme Activity Studies in Single Vesicles Project group discussion 17:00 18:00 Workshop Group Discussion 20:00 21:00 Thomas Tschentscher Dynamic Processes Studied by X-Ray Scattering 21:00 21:30 Group presentation with 3 min. poster presentations: Theory + NanoElectronics

8 Sunday 3/2-08 NanoWires Chair: K. Martinez 9:00 9:40 Karen Martinez Using Nanowires for Sensing of Biological Events 9:40 10:10 Brian Skov Sørensen About the Physical Platform of the BioFET (an in-house status) 10:10 10:30 Coffee break 10:30 11:00 Lars Iversen How to design recognition motifs for Bio-FET 11:00 11:30 Yi-Chi Liu Functionalization of Silicon Nanowires for Scientific Protein Immobilization 11:30 12:00 Nathalie Rieben Development of Suitable Recognition Motifs for Glutamate Sensing Chair: R. Feidenhans l 9:00 10:30 Presentation of results from the project groups Chair: M. Meedom Nielsen 11:00 12:30 Discussion of the results plans for the future Project group discussion 17:00 18:00 Workshop Group Discussion 20:00 Surprise Event Monday 4/2-08 7:45 Departure

9 Practical Information: The Hotel: Sportshotel Alpenland Maria Alm Dorf 86 A-5761 Maria Alm Tlf: p 0 Fax: mariaalm@alpenland.at Breakfast: 7:00 10:00 Lunch: A la carte at the hotel and in restaurants in town Dinner: 18:30 20:00 Travel: Departure CHP: 29/01/08 at 10:50 Flight Number: SK1665 Arrival Munich: 12:25 Bus Departure Munich: 13:00 Arrival Maria Alm: 16:30 Departure Maria Alm: 7:45 Departure Munich: 04/02/08 at 13:05 Flight number: SK1666 Arrival CHP: 14:40 Caution: This is for the majority of participants; check your personal travel plan before traveling. Contact: Guides: Ane: a.k.skielboe@gmail.com Frederik: NSC contact: Thomas: TJS@2gf.dk

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