High performance mass spectrometry - new methods & applications in life science

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International Workshop High performance mass spectrometry - new

Laboratory of Analytical Chemistry and Biopolymer Structure Analysis

Washington University Shuying Liu Chinese Academy of Sciences Alina

Michael Glocker Proteome Center Rostock Christoph Borchers University

1 International Workshop High performance mass spectrometry - new methods & applications in life science August 26 th -28 th, 2009 Laboratory of Analytical Chemistry and Biopolymer Structure Analysis Guest speakers Ken Tomer NIEHS, Research Triangle Park Michael Gross Washington University Shuying Liu Chinese Academy of Sciences Alina Zamfir University of Timisoara Marco Gaspari University of Catanzaro Michael Glocker Proteome Center Rostock Christoph Borchers University of Victoria Hans-Jörg Niebel CovalX, Zürich Organiser: Prof. Dr Dr h.c. Michael Przybylski

International Workshop: High performance mass spectrometry - new methods & applications in life sciences Organising committee Michael Przybylski Stefan Slamnoiu Andreas Marquardt Dmitry Galetskiy

2 International Workshop: High performance mass spectrometry - new methods & applications in life sciences Organising committee Michael Przybylski Stefan Slamnoiu Andreas Marquardt Dmitry Galetskiy Marilena Manea Iuliana Şuşnea Laboratory of Analytical Chemistry & Biopolymer Structure Analysis University of Konstanz Universitätsstrasse Konstanz, Germany We gratefully acknowledge the support by the following companies and institutions: Biosensor GmbH Bruker Daltonik GmbH CovalX AG Genzyme CEE GmbH Konstanz Research School Chemical Biology Shimadzu Deutschland GmbH Thermo Scientific Waters GmbH

International Workshop: High performance mass spectrometry - new methods & applications in life sciences 26 th - 28 th August, 2009 University of Konstanz Laboratory of Analytical Chemistry &

3 International Workshop: High performance mass spectrometry - new methods & applications in life sciences 26 th - 28 th August, 2009 University of Konstanz Laboratory of Analytical Chemistry & Biopolymer Structure Analysis Programme Wednesday, 26 th August, 2009 Lecture room A :00 Registration 17:30 Welcome Michael Przybylski Welcome address Dean, FB Chemie Session A: Bioaffinity-Mass Spectrometry I: New Methods Chair: Michael Gross 17:45 Michael Przybylski, University of Konstanz Bioaffinity- Mass Spectrometry: Introduction 18:00 Thomas Gronewold, Biosensor GmbH Bonn Combination of biosensor affinity measurement and mass spectrometry: Investigating protein concentration, binding characteristics and conformation 18:30 Mihaela Dragusanu, University of Konstanz Online bioaffinity- mass spectrometry for structural identification and quantification of protein interactions 19:00 Discussion 19:30 Welcome buffet

4 Thursday, 27 th August, 2009 A 704 Session B: New developments in high performance mass spectrometry Chair: Ken Tomer 09:00 Eugen Damoc, Thermofisher Scientific, Bremen TBA 09:40 Ralf Falter, Bruker Daltonik, Bremen The Benefit of Ultrahigh Resolution in a QTOF for Life Science Applications 10:20 Jörg Niebel, Covalx AG, Zürich Protein complex analysis by High mass Maldi ToF mass spectrometry 11:00 Coffee Break 11:20 Shuying Liu, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences A New Method for Analysis of Disulfide-Containing Proteins by Matrix-Assisted Laser Desorption Ionization (MALDI) Mass Spectrometry 12:00 Marco Gaspari, University of Catanzaro High-throughput, accurate quantitation of major serum proteins on a quadrupole time-of-flight mass spectrometer 12:40 Keith Compson, Waters Corp., Manchester Developments in ion mobility mass spectrometry 13:20 Lunch

5 Session C Biological and biomedical applications Chair: Marilena Manea, Shuying Liu 14:30 Alina Zamfir, University of Timisoara Nanochip- mass spectrometry for biomarker discovery in hereditary diseases 15:10 Corina Flangea, University of Timisoara Mass spectrometric screening and sequencing of glycosylaminoglycans expressed in biological tissues 15:40 Iuliana Susnea, University of Konstanz Unknown-genome -proteomics: A new NAD(P)- dependent epimerase/dehydratase revealed by N-terminal sequencing, inverted PCR and high resolution mass spectrometry 16:10 Michael Preiss, Genzyme CEE GmbH, Konstanz Rare diseases the challenge for diagnostics of LSD s 16:40 Coffee Break 17:10 Christoph Borchers, University of Victoria High field FTICR mass spectrometry for structural proteomics and metabolomics 18:00 Discussion Get-together & Refreshments 20:00 Dinner Hotel Barbarossa

6 Friday, 28 th August, 2009 A 704 Session D: Bioaffinity-Mass Spectrometry II: Applications Chair: Michael Przybylski, Michael Glocker 09:00 Michael Gross, Washington University St.Louis Perspectives of bioaffinity mass spectrometry in biomedical applications 09:45 Ken Tomer, NIEHS Research Triangle Park Mass spectrometry of antigenic determinants: From linear to discontinuous with cryptic stopovers 10:30 Coffee Break 11:00 Michael Przybylski, University of Konstanz Bioaffinity- Mass spectrometry: Application to protein interactions 11:45 Michael Glocker, Proteome Center Rostock Affinity-MS concepts for Individualized Medicine: Patient profiling by multiparametric analysis 12:30 Concluding Remarks & Discussion Michael Gross, Ken Tomer, Michael Glocker, Michael Przybylski End of workshop -- Lunch buffet

[ Plenary Lectures Registration Abstract Submission Short Communications Posters ] DEADLINE abstract submission is now September 15th 2015!

2015 SGMS Meeting [ Plenary Lectures Registration Abstract Submission Short Communications Posters ] The 33rd meeting of the SGMS will be held at the Dorint Resort Blüemlisalp Beatenberg, October 29 30,