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6 , 218,1 01 +%I " D ezf 0'W. (" 326. *x* y"r *..,f5 (! "e5* %. #' K9 : Michael F. Holick. Vitamin D Deficiency. N Engl J Med. 2007;357: Bringhurst F.R, Demay M.B, Kronenberg H.m.Willims. 11.ed. Saunders. Chapter 27, 2008; Morad Zadeh K, Larijani B, Keshtkar AA, Hossein Nezhad A, Rajabian R, Nabi Poor I, et al. Normal values of vitamin D and prevalence of vitamin D deficiency among Iranian population. Sci J Kurdistan U Med Sci.2006;10:33-43[persian]. 4- Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr. 2006;84: Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81: Meddeb N, Sahli H, Chahed M, Abdelmoula J, Feki M, Salah H, et al. Vitamin D dekciency in Tunisia. Osteoporos Int. 2005;16: Du X, GreenKeld H, Fraser DR, Ge K, Trube A, Wang Y. Vitamin D dekciency and associated factors in adolescent girls in Beijing. Am J Clin Nutr. 2001;74: Gordon CM, DePeter KC, Feldman HA, Grace E, Emans SJ. Prevalence of vitamin D dekciency among healthy adolescents. Arch Pediatr Adolesc Med. 2004;158: Mirsaeid Ghazi AA, Rais ZF, Pezeshk P, Azizi F. Seasonal variation of serum 25-hydroxy-D3 in residents of Tehran. J Endocrinol Invest. 2004;27: Moussavi M, Heidarpour R, Aminorroaya A, Pournaghshband Z, Amini M. Prevalence of Vitamin D dekciency in Isfahani High School Students in Horm Res. 2005;64: Ostad Rahimi Aa, Zarghami Nb, Sadighi Ac. Relationship Between Vitamin D and Nutritional Status in Healthy Reproductive Age Women. Int J Endocrinol Metab. 2006; 4:

7 9, < 1 +=>?* 9:;8, D Abstract Original Article Vitamin D Deficiency and Its Cut-off Point among Young Teenagers A. Talaei 1, N. Yadegari 2, M. Rafee 3, M.R Rezvanfar 4 Background and Aim: Vitamin D has a basic role in bone development and metabolism. Regarding high prevalence of vitamin D deficiency in Iran, we aimed to investigate its point prevalence in Arak, Iran and determine a cut-off point for vitamin D deficiency in the region. Materials and Methods: In a cross-sectional study,420 adolescents (220 girls, 200 boys) aged years old were selected using a multistage sampling. Plasma level of vitamin D and PTH were evaluated using radio immune assay and immuno radio metric assay, respectively. The relation between vitamin D and PTH was assessed through scatter diagram and the cut-off points for vitamin D deficiency were detected accordingly. The prevalence of vitamin D deficiency in different cut-off points, as well as, the associated factors were analyzed using SPSS Student t-test was used to compare the girls and the boys. Results: Considering 25(OH) vit-d level <20 ng/ml as vitamin D deficiency, 84% of the students were vitamin D deficient (99.1% of girls, 66.5% of boys) (P=0.001). Scatter diagram showed three cut-off points for vitamin D deficiency as 25(OH) vit-d level < 13, 21, 33 ng/ml. Conclusion: Vitamin D deficiency is more prevalent among girls than boys and increases with increased weight (P=0.05). A cut-off point of 25(OH) vit-d <13 ng/ml is recommended for detecting vitamin D deficiency in Arak, Iran. Key Words: Parathormone, vitamin D deficiency, cut-off point. Journal of Birjand University of Medical Sciences. 2011; 17(3): Received: February 26, 2011 Accepted: November 08, Corresponding Author; Assistant professor, endocrinologist, Arak University of Medical Sciences talaei@arakmu.ac.ir 2 Nutritionist, Arak University of Medical Sciences 3 Epidemiologist, Assistant professor, Arak University of Medical Sciences 4 Assistant professor, endocrinologist, Arak University of Medical Sciences 216

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