October 08-11, Co-Organizer Dr. S D Samantaray Professor & Head,

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1 A Journey towards Systems system Biology biology :: Biocomputing of of Hi-throughput Omics omics Data data October 08-11, 2018 Coordinator Dr. Anil Kumar Gaur Professor & Head Department of Molecular Biology & Genetic Engineering Organizer Dr. Gohar Taj Scientist Incharge Sub-DIC Bioinformatics Co-Organizer Dr. S D Samantaray Professor & Head, Organizing Committee Dr. B.R. Singh Associate Professor, MBGE Dept of Computer Engineering Dr. Ashutosh Dube College of Technology Junior Research Officer Department of Biochemistry Department of Molecular Biology & Genetic Engineering College of Basic Sciences & Humanities G. B. Pant University of Agriculture & Technology Pantnagar, Uttarakhand, IN.

2 About Workshop Aims: Systems biology seeks to integrate different levels of information to understand how biological systems function. This is accomplished by studying the relationships and interactions between various parts of the particular system of interest, which could range over orders of magnitude, from molecular assemblies to subcellular, multicellular, and tissue/organ systems. Plant structure and function are complex biological systems and as nature of fact, systems biology is based on the premise that their properties cannot be understood by focusing on any one aspect of their highly interacting components. As a sessile organism, plants should adjust their metabolism to dynamic changes in their environment, including biotic and abiotic stresses. Tight coordination of branched metabolic or signaling networks must be central to the physiological changes needed to continuously face these fluctuating conditions. Moreover, the system s properties of interest often are embodied in its dynamics. Nonetheless, we are still far from the initial objective of fully understanding how a given system works. The main aim of this workshop is to acquaint the participants with an understanding of the importance of scientific challenge to integrate every piece of biological information including Physiology, Molecular biology and Computational & Systems Biology into a cohesive whole, requiring an iterative process between experimental data and their Insilico analysis. Indeed, once data are integrated and models describing the system studied are designed. Accordingly data should be produced and reconciled with recent models, and discrepancies between observed data and models should be used to design various perturbations, which are analyzed by means of systematic approaches. Systems biology needs the whole process to be repeated iteratively until various model and observed data converge. Since from starting we run public workshops which are continually improved by integrating ideas and suggestions from our participants. This steady feedback loop with our participants helps the workshops stay current with evolving user expectations in Plant systems biology. This workshop has been conceptualized by the professionals having substantial experience in the field of plant physiology, molecular biology and computational & systems biology.

3 Objectives: How different domains of biology at various levels converge, bioinformatics, has been realized for its importance, therefore organizing the workshop with following objectives: Analysis of large amounts of omics (Genomics, Proteomics, Transcriptomics, and Metabolomics) data of plant biology through big data analysis computational tools. Introduces fundamental and applied bioinformatics research in the field of life sciences. Highlights relevant databases, softwares, tools and web resources developed till date to make ease of access for researchers working todecipher plant responses towards stresses. Molecular modeling and docking studies for Characterisation of the binding behaviour which plays an important role in rational design of drugs as well as to elucidate fundamental biochemical processes Contents: Molecular and Structure biology: Studying the architecture, shape, and dynamics of biological micro/macromolecules is paramount for understanding the basic mechanisms that drive the essential processes of all life. Macromolecules such as proteins and nucleic acids carry out most of the functions of a cell, and are able to perform these functions by adopting assemblies of structures under native state conditions. Structural biology is concerned with the driving forces and interactions that determine the three-dimensional shapes and dynamics of bio-molecules. Big data analysis: All organisms operate through activating and repressing genes in a coordinated and timely manner between biological conditions. Gene or protein cannot work in isolation. Understanding how interactions are formed and activated at specific time points or conditions is a central part of understanding how specific cells work. With the increase of high-throughput methods it is possible to obtain large amount of data to study a cellular system from complementary aspects more easily. The vast quantity of data produced also enables data re-use and provokes new methods for integration of heterogeneous data. NGS Analysis: Introduction to common NGS data analysis and sequencing technologies from a data analyst s view and applications of sequencing technologies in the plant biology. Introduction to file formats and databases for pre-processing of raw reads, quality control. Introduction and important role of Transcriptome/Genome/GBS data in Plant systems biology.

4 Methodology: The hands-on Modules and lectures from experts of Govt. & Private organizations. LEVEL OF PARTICIPANTS: Research scholars, scientists (National/ International) PREREQUISITES: Acquaintance with computer and internet Boarding & lodging arrangements: University guest house (Provided on payment basis) Registration Details How to Register: In order to register for the course, send the completed registration form along with Demand Draft (DD) as registration fees Rs. 2000/- (without accommodation) in favor of Comptroller, GBPUA&T, Pantnagar. The complete registration form must be duly forwarded from the competent authorities (HOD/Dean/Director/Principal of respective institutions) to Head, Department of Molecular Biology & Genetic Engineering, GBPUA&T, Pantnagar , Udham Singh Nagar Uttarakhand, India by Speed Post / Registered post latest by 25 th September Selected candidates will be ed by 27 th September 2018.

5 REGISTRATION FEE Without Accommodation REGISTRATION FEE With Accommodation India Rs Actual payment of accommodation SAARC $200 $200 Other Countries $200 $200 by participant Last date of application submission: 25 th September 2018 Accommodation: The boarding and lodging for the participants will be made in university guest house only on request in advance. Extra payment has to be done for this. Number of participants The maximum number of participants will be limited to 30. Selection will be based on first come first serve basis. Note Those who have personal laptop computer(s) are encouraged to bring during training.

6 Venue & Accommodation: GBPUA&T, Pantnagar Contact Address : Coordinator / Scientist Incharge, Sub-DIC Bioinformatics, Department of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G B Pant University of Agriculture & Technology, Pantnagar, Udham Singh Nagar , INDIA Phone : Mob: Fax : bioinfo.pantnagar@gmail.com gohartajkhan@rediffmail.com Web Address: Demand Draft (DD) Detail: