Feasibility study of TULIP: a TUrning
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1 Feasibility study of TULIP: a TUrning LInac for Protontherapy ICTR-PHE 2012 Conference A. Degiovanni U. Amaldi, M. Garlasché, K. Kraus, P. Magagnin, U. Oelfke, P. Posocco, P. Riboni, V. Rizzoglio
2 TULIP: a Single Room Facility project Why single room facilities? Proton therapy beneficial to at least 12% of X-ray patients (ENLIGHT studies outcome) ~ patients/year every 10'000'000 people 1 proton room every 1.5 Milion inhabitants Advantages Spread the investement cost Hospital based protontherapy (not dedicated centres) Technical challenges Size and cost of the machine Dose delivery modalities Treatment time ICTR-PHE A. Degiovanni 2
3 A cyclinac based solution TULIP = TUrning LInac for Protontherapy C-band linac Section 1 C-band linac Section 2 cyclotron Line with 2% momentum acceptance RF rotating joints Beam dose delivery RF Power sources Mechanical structure ICTR-PHE A. Degiovanni 3
4 The CYCLINAC timeline 1993: first Cyclinac proposal 2003: test on LIBO-62 MeV (TERA-CERN-INFN) [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) ] 2007: first CABOTO design * See abs. #227 by S. Verdú Andrés 2010: CABOTO-C design (*) : LIGHT 1st UNIT inaugurated by CERN DG Prof. R. Heuer (courtesy of ADAM SA.) ICTR-PHE A. Degiovanni 4
5 Electric field distribution ib ti (HFSS) The linac and RF system coupl. cell on side acc. cell on axis excited cavity acc. tanks un-excited cavity TANK space for quadrupoles RF cavities in π/2 mode Accelerating TANKS Acc. units with space for PMQs H 11 polarizer (Igor Syratchev, CERN) linear polarization circular polarization ICTR-PHE A. Degiovanni 5
6 The CYCLINAC timeline 1993: first Cyclinac proposal 2003: test on LIBO-62 MeV (TERA-CERN-INFN) 2007: first CABOTO design * See abs. #227 by S. Verdú Andrés 2010: CABOTO-C design (*) E 0 = 15 MV/m [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) ] E 0 = 16 MV/m : LIGHT 1st UNIT inaugurated by CERN DG Prof. R. Heuer (courtesy of ADAM SA.) ICTR-PHE A. Degiovanni 6
7 The choice of the frequency TULIP project requires shorter linacs Higher gradients are needed (~35 MV/m) Reliability in terms of BDR High gradient tests (S- and C- band) in collaboration with CLIC see poster #203 (Cyclinac group) Size of RF rotating joints for power transmission Power source availability C- band : GHz ICTR-PHE A. Degiovanni 7
8 TULIP preliminary GHz (C-band) from 35 to 210 MeV Quantity [unit] Section 1 Section 2 Output energy [MeV] Total length [m] Avg. E 0 [MV/m] Max. E SURFACE [MV/m] Number of units 1 (4) 7 Peak Power [MW] Repetition rate [Hz] Pulse length [μs] ICTR-PHE A. Degiovanni 8
9 Fast active energy variation E) (E) / N(E dn( Energy [MeV] ICTR-PHE A. Degiovanni 9
10 Fast active energy variation Active energy variation in the range MeV Energy spread within 2 mm distal fall-off Active spot scanning with tumour multipainting ICTR-PHE A. Degiovanni 10
11 TULIP beam transfer line With Δp/p = ±2% ΔR/R = ± 7% For R = 30 cm ΔR = ± 2.1 cm R R E E p p cm cm cm 32.9 cm cm ICTR-PHE A. Degiovanni 11
![Section II [kg] Linac 340](/docs-images/88/115373014/images/12-1.jpg "460 Beam Structure 3400")
12 Supporting structure C-band linac Section I [kg] Section II [kg] Linac Beam Structure Ancillaries ICTR-PHE A. Degiovanni 12
![TULIP Mechanical Design Bearings Rot. axis Actuators 1 2 3 Total estimated 60 weight [tons] Max ang acceleration 0.](/docs-images/88/115373014/images/13-0.jpg "5 [rad/s 2 ] Max rotation 1.5 speed* [rpm] * derived from norm EN 60601 and max vel considerations 28.02.2012 ICTR-PHE 2012 - A.")
13 TULIP Mechanical Design Bearings Rot. axis Actuators Total estimated 60 weight [tons] Max ang acceleration 0.5 [rad/s 2 ] Max rotation 1.5 speed* [rpm] * derived from norm EN and max vel considerations ICTR-PHE A. Degiovanni 13
14 Novel study of dynamic dose delivery simulation of dynamic delivery via computer software based on treatment plan data for a static dose delivery dynamic parameters (repetition rate, v Gantry, v Couch ) TPS: Calculation of static plan Plan data: D ij matrices Spot positions Spot weights Tulip machine parameters: Gantry speed Repetition rate Couch speed Number of protons Dynamic dose calculation l Dose distribution more information: Poster 156 by Kim Kraus (DKFZ, Heidelberg) ICTR-PHE A. Degiovanni 14
15 Novel study of dynamic dose delivery dynamic dose delivery to a cylindrical target volume different combinations of dynamic parameters the higher the gantry speed the higher must be the repetition rate to deliver all spots D Diff =D dyn (f= 100Hz, v Gantry = 1 /s) - D static Difference dose distribution : Good agreement of the dynamic and static dose distributions within the target! ICTR-PHE A. Degiovanni 15
16 Summary First design in C-band for a single room facility: Linac and RF design Mechanical design Novel dose delivery Cyclinac concept Future developments: - Optimization of Section 1 - Final mechanical spec. Compact beam line TULIP New dose delivery e Combine acceleration and gantry flexibility with active energy variation New mechanical design ICTR-PHE A. Degiovanni 16
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