Company Profile SALTOSE. New Bio-Culture & Enzyme Combination

Transcription

1 Company Profile Company name Head office PIC-BIO,Inc. Registered office; Gosaku Bld., Nishigotanda, Shinagawa-ku, Tokyo, , Japan TEL: FAX: Warehouse; 7399, Izumi-cho, Izumi-ku, Yokohama-shi, Kanagawa, , Japan Subsidiary companies; PIC-BIO (Asia), Inc. 2F., No. 8, Sec. 1 Nanjing E. Rd., Taipei, 10444, Taiwan Tel : Founded President Main banker Company products May 25 th, 1972 Yoshimi OKUMURA Sumitomo Mitsui Banking Corporation Mizuho Bank, Ltd. 1. Probiotics Feed Additive 2. Natural Herb Feed Additive 3. Humic Natural Complex 4. Pure Natural Fulvic 5. Semen Extender for Swine 6. Natural Health Foods SALTOSE Our Bacillus subtilis which are screened among 10,000 strains and special enzymes ensure the safety and health of poultry and livestock by controlling harmful bacteria (Salmonella, E. coli, Clostridium) and parasites (Coccidium, Cryptosporidium)

2 Heat resistance Feed tested A corporation's feed PIC-BIO INC. has been involved in research and development of remedies for not only production of Mixing ratepoultry and livestock adding 0.1% into feed antibiotic-free but also enzyme products that are capable of preventing migration of zoonotic diseases as replacement of antibiotic Pelletizing temperature for number of years since PIC-BIO INC. was incorporated. One of the enzyme products is SALTOSE bypelletizing, its trade name efficacy has been recognized by poultry Test period 15mins of thenwhose cooling at room temperature and livestock industries in Japan and foreign countries. 8 8 (Before)5.04 x 10 CFU/g (After)4.95 x 10 CFU/g Result(pelletizing) Compatibility with antibiotics and coccidiostats What is SALTOSE? Not sensitive to antibiotic Sensitive to antibiotic SALTOSE is one of leading probiotics which contains Bacillus group, Enterococcus group Lincomycin Spectinomycin, Lincomycin, and unique enzymes. SALTOSE can prevent and treat the bacterial and parasitic Terramycin, Aureomycin, Amprolium, Colistin, Enromycin, Chloramphenicol, Penicillin, diseases with Tylosin, the characteristics oftiamulin, used bacteria and enzymes, Framycetin, Neo-Terramycin, Kanamycin, Carbadoxand improve the Destomycin, productivity forneomycin, poultry Virginiamycin, and livestock and aquaculture. Ethopabate Ingredients and Characteristics Used Bacillus strains and main enzymes WeIngredients have selected 5 strains of Bacillus group among more than ten thousand strains of Bacillus group which do not produce antibiotics, but produce unique enzymes which can 350 U/g minimum Beta-xylanase break down the cell wall of bacteria and oocyst of some important parasites. Main Enzyme 12,000 PU/g minimum Protease The Bacillus group; Bacillus group 1.Bacillus licheniformis 2.Bacillus subtilis Enterococcus pumilusgroup 3.Bacillus The main enzymes; 3,700 U/g minimum Cell Wall Lyase 1. Disease Control Bacillus licheniformis 9 diseases and Strong bacteriolytic effects against Bacillus subtilis more than 1.0bacterial x 10 cfu/g antiprotozoal effect against parasitic diseases through unique Bacillus pumilus Enterococcus enzyme faecalis Cell-Wall Lyase. 8 more than 1.0 x 10 cfu/g 2. Improvement in Digestion Enterococcus faecium of the cellsulfate wall of(mgso4), feed substances for * Main ingredients in medium are Soybean Cake, Disintegration Cornstarch, Magnesium and Phosphate. 1.Beta-Xylanase improvement of productivity by enhancing 2.Cell-Wall Lyase Appearance digestion, feed conversion, and body weight gain. 3.Protease Yellow-white powder, passing #60 mesh screen, No change in the appearance after 3. Odor Control processing into pellets. Used Lactic Acid Bacteria Dosage and administration Decrease of Ammonia and Hydrogen Sulfide in their excreta. Poultry and Livestock: kg per 1,000kg feed. 1. Improving ecological environment in intestines The Enterococcus group; Attention 2. Enhancing multiplication and growth of bifido bacteria 1.Enterococcus faecalis Keep in dry, cool and dark place. Do not mix other microorganism. 3. Prevention and elimination of harmful bacteria 2.Enterococcus faecium Packing 4. Keeping microorganisms in rumen and caecum at normal conditions 20kg / Bag Harmful Bacteria 5. Enhancing appetite of animals and also enhance their growth PIC-BIO,Inc - JAPAN - Unique Enzymes (Cell-Wall Lyase etc.) Gosaku Bld., Nishigotanda, Shinagawa-ku, Tokyo TEL : FAX : pic@pic-bio.co.jp Website :

3 SALTOSE Degradation Effects on Parasite 2-12 < < Coccidium Cryptosporidium oocyst (Poultry) (Cattle) > > Prepared culture media for SALTOSE and inoculated Cryptosporidium for observation of degradation effects. Before SALTOSE Coccidium oocyst germinated and sporocyst developed After SALTOSE Coccidium oocyst was dissolved completely and its original shape disappeared. Before SALTOSE application < Coccidium oocyst (Cattle) > After 12 hours * Blue stick bacteria are SALTOSE bacteria. Finally, Cryptosporidium was dissolved completely and its original shape disappeared. Before SALTOSE Coccidium oocyst germinated and sporocyst developed. After SALTOSE Coccidium oocyst was dissolved completely and its original shape disappeared.

4 SALTOSE Degradation Effects on Parasite 2-12 < < Coccidium Cryptosporidium oocyst (Poultry) (Cattle) > > Prepared culture media for SALTOSE and inoculated Cryptosporidium for observation of degradation effects. Before SALTOSE Coccidium oocyst germinated and sporocyst developed After SALTOSE Coccidium oocyst was dissolved completely and its original shape disappeared. Before SALTOSE application < Coccidium oocyst (Cattle) > After 12 hours * Blue stick bacteria are SALTOSE bacteria. Finally, Cryptosporidium was dissolved completely and its original shape disappeared. Before SALTOSE Coccidium oocyst germinated and sporocyst developed. After SALTOSE Coccidium oocyst was dissolved completely and its original shape disappeared.

5 SALTOSE Inhibitory Effects on Bacteria 2-1 < Salmonella Enteritidis > Prepared culture media for S. Entertidis and inoculated the follwing bacteria. 1, 6, 7, 8, 9 : SALTOSE T : Competitor C : Competitor S1 : S. Typhimurium S2 : S. Gallinarum SALTOSE shows their antibacterial activities with the formation of inhibition ring. < Salmonella Enteritidis and Salmonella Gallinarum > RL bacteria were inoculated in YM-SE and YM-SG culture medium for observation of inhibition ring. YM : Yeast and Malt RL : SALTOSE bacteria SE : S. Enteritidis SG : S. Gallinarum SP : other Bacillus subtilis 1. SALTOSE produced a large inhibition ring, which indicates strong control effect on S. Enteritidis and S. Gallinarum. 2. Other Bacillus subtilis indicated almost no control effect.

6 SALTOSE Inhibitory Effects on Bacteria 2-2 < Clostridium > Prepared culture medium for Clostridium and inoculated Bacillus licheniformis of SALTOSE (Right side) and the other Bacillus licheniformis (Left side) bacteria for observation of growth and inhibition ring. 12 hours 32 hours 60 hours Graph for Right side ( Dimension ( cm2 ) of bacteria and inhibition ring ) 30 hours after the inoculation, Bacillus licheniformis of SALTOSE stopped their growth due to completing the absorption of nutrients from culture medium. However, inhibition ring continued to expand, and dissolved Clostridium.

7 Antagonistic The Other Data Effects on Bacteria Testing result (Excreta) < Salmonella Enteritidis < Salmonella < E. (840) coli and (K-88) Gallinarum Salmonella > > Infantis (837) > 1. <Reduction of generating ammonium odor at poultry farm> S. Gallinarum were inoculated in DP (Left side) E. coli and (K-88) YM (Right and side) SALTOSE culture from bacteria chicken medium, farm were and was then, each bacterium was inoculated in the same inoculated point for on observation the same culture of reduced antagonistic medium. due to effects. application Ammonia (ppm) SALTOSE Time (Min.) It is observed that SALTOSE of SALTOSE shows more antibacterial SALTOSEactivities against E. coli. Deodorant A Deodorant B R : } S : N : Bacillus group P : L : Generation of ammonia 2. <Comparison of digestibility> S: SALTOSE < Useful Bacteria (Lactic acid bacteria and Bifido bacteria) > Result: SALTOSE treatment can improve the DP : Dexton and Pepton YM : Yeast and Malt digestion, 1. The growth so the amount power of of excreta SALTOSE becomes SE : S. Enteritidis SG : S. Gallinarum half bacteria as compared is with the the control. strongest, and RL : SALTOSE bacteria SALTOSE bacteria controls SP : Other Bacillus subtilis S. Gallinarum bacteria. 2. Other Bacillus subtilis indicated poor growth power. 3. <Bacterial count in the excretion of chickens> Competitor SALTOSE The count of Bacillus bacteria in the excretion remained almost Competitor did not absorb the inoculated No. of bacteria log cfu/gram Salmonella bacteria. SALTOSE absorbed unchanged; the inoculated however, the total Salmonella bacteria. bacteria count was reduced as Lactic acid bacteria Bifido dosage bacteria rate was increased. SALTOSE did not damage the useful bacteria. C: Control Applied qty

8 Antagonistic The Other Data Effects on Bacteria Testing result (Excreta) < Salmonella Enteritidis < Salmonella < E. (840) coli and (K-88) Gallinarum Salmonella > > Infantis (837) > 1. <Reduction of generating ammonium odor at poultry farm> S. Gallinarum were inoculated in DP (Left side) E. coli and (K-88) YM (Right and side) SALTOSE culture from bacteria chicken medium, farm were and was then, each bacterium was inoculated in the same inoculated point for on observation the same culture of reduced antagonistic medium. due to effects. application Ammonia (ppm) SALTOSE Time (Min.) It is observed that SALTOSE of SALTOSE shows more antibacterial SALTOSEactivities against E. coli. Deodorant A Deodorant B R : } S : N : Bacillus group P : L : Generation of ammonia 2. <Comparison of digestibility> S: SALTOSE < Useful Bacteria (Lactic acid bacteria and Bifido bacteria) > Result: SALTOSE treatment can improve the DP : Dexton and Pepton YM : Yeast and Malt digestion, 1. The growth so the amount power of of excreta SALTOSE becomes SE : S. Enteritidis SG : S. Gallinarum half bacteria as compared is with the the control. strongest, and RL : SALTOSE bacteria SALTOSE bacteria controls SP : Other Bacillus subtilis S. Gallinarum bacteria. 2. Other Bacillus subtilis indicated poor growth power. 3. <Bacterial count in the excretion of chickens> Competitor SALTOSE The count of Bacillus bacteria in the excretion remained almost Competitor did not absorb the inoculated No. of bacteria log cfu/gram Salmonella bacteria. SALTOSE absorbed unchanged; the inoculated however, the total Salmonella bacteria. bacteria count was reduced as Lactic acid bacteria Bifido dosage bacteria rate was increased. SALTOSE did not damage the useful bacteria. C: Control Applied qty

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10 Antagonistic The Other Data Effects on Bacteria Testing result (Excreta) < Salmonella Enteritidis < Salmonella < E. (840) coli and (K-88) Gallinarum Salmonella > > Infantis (837) > 1. <Reduction of generating ammonium odor at poultry farm> S. Gallinarum were inoculated in DP (Left side) E. coli and (K-88) YM (Right and side) SALTOSE culture from bacteria chicken medium, farm were and was then, each bacterium was inoculated in the same inoculated point for on observation the same culture of reduced antagonistic medium. due to effects. application Ammonia (ppm) SALTOSE Time (Min.) It is observed that SALTOSE of SALTOSE shows more antibacterial SALTOSEactivities against E. coli. Deodorant A Deodorant B R : } S : N : Bacillus group P : L : Generation of ammonia 2. <Comparison of digestibility> S: SALTOSE < Useful Bacteria (Lactic acid bacteria and Bifido bacteria) > Result: SALTOSE treatment can improve the DP : Dexton and Pepton YM : Yeast and Malt digestion, 1. The growth so the amount power of of excreta SALTOSE becomes SE : S. Enteritidis SG : S. Gallinarum half bacteria as compared is with the the control. strongest, and RL : SALTOSE bacteria SALTOSE bacteria controls SP : Other Bacillus subtilis S. Gallinarum bacteria. 2. Other Bacillus subtilis indicated poor growth power. 3. <Bacterial count in the excretion of chickens> Competitor SALTOSE The count of Bacillus bacteria in the excretion remained almost Competitor did not absorb the inoculated No. of bacteria log cfu/gram Salmonella bacteria. SALTOSE absorbed unchanged; the inoculated however, the total Salmonella bacteria. bacteria count was reduced as Lactic acid bacteria Bifido dosage bacteria rate was increased. SALTOSE did not damage the useful bacteria. C: Control Applied qty

11 Company Profile Company name Head office PIC-BIO,Inc. Registered office; Gosaku Bld., Nishigotanda, Shinagawa-ku, Tokyo, , Japan TEL: FAX: Warehouse; 7399, Izumi-cho, Izumi-ku, Yokohama-shi, Kanagawa, , Japan Subsidiary companies; PIC-BIO (Asia), Inc. 3F, No.23, Lane 58, Shih Pai Road Sec.1, Taipei, 11271, Taiwan Tel : Founded President Main banker Company products th May 25, 1972 OKUMURA Koichiro Sumitomo Mitsui Banking Corporation Mizuho Bank, Ltd. 1. Probiotics Feed Additive 2. Natural Herb Feed Additive 3. Humic Natural Complex 4. Pure Natural Fulvic 5. Semen Extender for Swine 6. Natural Health Foods

12 Heat resistance Feed tested A corporation's feed PIC-BIO INC. has been involved in research and development of remedies for not only production of Mixing ratepoultry and livestock adding 0.1% into feed antibiotic-free but also enzyme products that are capable of preventing migration of zoonotic diseases as replacement of antibiotic Pelletizing temperature for number of years since PIC-BIO INC. was incorporated. One of the enzyme products is SALTOSE bypelletizing, its trade name efficacy has been recognized by poultry Test period 15mins of thenwhose cooling at room temperature and livestock industries in Japan and foreign countries. 8 8 (Before)5.04 x 10 CFU/g (After)4.95 x 10 CFU/g Result(pelletizing) Compatibility with antibiotics and coccidiostats What is SALTOSE? Not sensitive to antibiotic Sensitive to antibiotic SALTOSE is one of leading probiotics which contains Bacillus group, Enterococcus group Lincomycin Spectinomycin, Lincomycin, and unique enzymes. SALTOSE can prevent and treat the bacterial and parasitic Terramycin, Aureomycin, Amprolium, Colistin, Enromycin, Chloramphenicol, Penicillin, diseases with Tylosin, the characteristics oftiamulin, used bacteria and enzymes, Framycetin, Neo-Terramycin, Kanamycin, Carbadoxand improve the Destomycin, productivity forneomycin, poultry Virginiamycin, and livestock and aquaculture. Ethopabate Ingredients and Characteristics Used Bacillus strains and main enzymes WeIngredients have selected 5 strains of Bacillus group among more than ten thousand strains of Bacillus group which do not produce antibiotics, but produce unique enzymes which can 350 U/g minimum Beta-xylanase break down the cell wall of bacteria and oocyst of some important parasites. Main Enzyme 12,000 PU/g minimum Protease The Bacillus group; Bacillus group 1.Bacillus licheniformis 2.Bacillus subtilis Enterococcus pumilusgroup 3.Bacillus The main enzymes; 3,700 U/g minimum Cell Wall Lyase 1. Disease Control Bacillus licheniformis 9 diseases and Strong bacteriolytic effects against Bacillus subtilis more than 1.0bacterial x 10 cfu/g antiprotozoal effect against parasitic diseases through unique Bacillus pumilus Enterococcus enzyme faecalis Cell-Wall Lyase. 8 more than 1.0 x 10 cfu/g 2. Improvement in Digestion Enterococcus faecium of the cellsulfate wall of(mgso4), feed substances for * Main ingredients in medium are Soybean Cake, Disintegration Cornstarch, Magnesium and Phosphate. 1.Beta-Xylanase improvement of productivity by enhancing 2.Cell-Wall Lyase Appearance digestion, feed conversion, and body weight gain. 3.Protease Yellow-white powder, passing #60 mesh screen, No change in the appearance after 3. Odor Control processing into pellets. Used Lactic Acid Bacteria Dosage and administration Decrease of Ammonia and Hydrogen Sulfide in their excreta. Poultry and Livestock: kg per 1,000kg feed. 1. Improving ecological environment in intestines The Enterococcus group; Attention 2. Enhancing multiplication and growth of bifido bacteria 1.Enterococcus faecalis Keep in dry, cool and dark place. Do not mix other microorganism. 3. Prevention and elimination of harmful bacteria 2.Enterococcus faecium Packing 4. Keeping microorganisms in rumen and caecum at normal conditions 20kg / Bag Harmful Bacteria 5. Enhancing appetite of animals and also enhance their growth PIC-BIO,Inc - JAPAN - Unique Enzymes (Cell-Wall Lyase etc.) Gosaku Bld., Nishigotanda, Shinagawa-ku, Tokyo TEL : FAX : pic@pic-bio.co.jp Website :