Faculty of Health, Science and Technology Chemistry. Syllabus

Transcription

1 Reg No: FAK2 2012/24:11 Faculty of Health, Science and Technology Chemistry Syllabus Course Approval The syllabus was approved by the Faculty Board of Health, Science and Technology on 11 March 2014, and is valid from the Autumn semester of 2014 at Karlstad University. It replaces the former syllabus KEMBA1/KEGAAK. Course Code: KEGAH0 Fundamental Chemistry I, 30.0 ECTS Credits (Grundläggande kemi I, 30.0 Swedish credit points) Degree Level: Bachelor Progressive Specialisation: G1N (First cycle, has only upper-secondary level entry requirements) Language of Instruction Swedish Prerequisites General admission requirements plus upper secondary education in Mathematics C, Physics A, och Chemistry B. or Mathematics 3b alternatively Matematics 3c, Physics 1a alternatively Physics 1b1+1b2 and Chemistry 2 Major Field of Study KEA (Chemistry) Learning Outcomes The aim of the course is that students acquire the basic knowledge and skills required for chemically oriented activities and for further studies. The course is offered in the form of modules with independently specified learning outcomes. and Form of Instruction The course comprises the following modules, the order of which can vary: -KEGAIK -KEGAKB -KEGAOO -KEGABB Module KEGAIK, Introductory Chemistry, 7.5 ECTS Credits Upon completion of the module students shall be able to: - explain the principles behind the periodic table and describe how symbols and notations give information about atomic number, mass number, and isotopes, - describe the properties of common elements and some of their compounds,

2 - name ionic compounds with simple and complex ions, give examples of different factors that affect solubility of an ionic compound and explain the concept of ionic bonding, - describe the electronic configuration of an atom by using the Pauli principle and explain how the electronic configuration affect the size, ionisation energy, and electron affinity of an atom, - give an account of the concepts empirical formula and formula unit, - explain the concepts lattice energy, unit cell, coordination number, and tetrahedron and octahedron holes, - describe the most common crystalline forms and exemplify, - describe how the hybridisation of atomic orbitals and Lewis structures can account for the geometry of molecules, - describe a covalent bond for diatomic molecules with the valence bond method, - explain the concepts electro negativity, dipole moment, formal charge, resonance structures, and bond enthalpy, - describe different types of intermolecular forces, - give an account of the hazards of a chemical laboratory environment, how to avoid accidents and how to act in an emergency, and generally demonstrate safe conduct in the laboratory, - use the basic equipment of a chemical laboratory, - communicate the result of laboratory experiments in the form of a scientific report. Instruction is in the form of lectures, exercises, laboratory experiments and a mandatory field trip. The aim of the field trip is to introduce the students to their future profession. The module comprises two units which are examined separately: A. Atom, Chemical Bonding, and Descriptive Inorganic Chemistry, 4.5 ECTS credits The unit provides a description of the development and application of theoretical and explanatory models of atoms and molecules. Current theories and models are applied to describe the conditions for the emergence and existence of chemical bonding. Chemical properties and description of elements and their formation are analysed and defined. B Laboratory Work, 3 ECTS credits The unit involves laboratory exercises, which are integrated with the A unit. Special attention is given to safety aspects and students have to pass a written test on these issues before being allowed to use the laboratory. Students are also required to procure and pay for approved protective equipment. Examination is in the form of continuous assessment of submitted laboratory reports and protocols. Access to individual laboratory work requires students to be well prepared which is checked randomly. Students are only given credit for laboratory work in a current term if all reports and protocols have been submitted within three weeks of the conclusion of the course. Late submissions will be graded at the earliest convenience, but no later than the next course opportunity. Module KEGAKB, Chemical Calculations Upon completion of the module students should be able to - use correct units and the correct number of significant digits in chemical calculations, - balance a chemical reaction formula and define the difference between molecular reaction formula, ion reaction formula and netto ion reaction formula, - calculate equilibrium constants and equilibrium concentrations for chemical equilibriums which can be treated as dynamic equilibriums, - explain how change in concentration, pressure, temperature and common reactant affect an equilibrium reaction, and how to use reaction ratio to determine if a system has reached equilibrium, - explain the terms ph, poh, pka, pkb, and pkw, the relations between them and the autoprotolysis of the water, - calculate ph at different stages during an acid-base titration and choose an appropriate indicator for the titration, - calculate ph changes in a buffer solution and explain how to make a buffer solution. - give an account of the difference between solubility product and solubility, and use the terms in calculations,

3 - solve simple problems involving electrolysis and complex equilibrium, - calculate concentration following dilution and determine concentration through titration, - calculate empirical formula and molecular formula of a compound, - calculate the yield of a chemical reaction, - use the general gas law to calculate physical properties of gases, - use the terms heat capacity and heat of reaction in simple thermal calculations, - determine reaction order and velocity constant for a reaction and use the Arrhenius equation to calculate activation energy and frequency factor. Instruction is in the form of lectures and computation and laboratory exercises. The exercise problems are culled from the students future professional work, for example the determination of the half-life of pharmaceuticals, or the buffering of blood. The module comprises two separately examined units: A. Chemical Calculations, 6 ECTS credits Stoichiometrics deals with the chemical terms and concepts necessary for calculating common chemical processes. Chemical equilibrium involves the description and calculation of different chemical processes which can be treated as dynamic equilibrium. Basic concepts for analytical methods in thermodynamics, kinetics and aqueous-chemistry are included. B. Laboratory Work 1.5 ECTS credits The laboratory unit consists of exercises related to module A. The exercises aim at illustrating and clarifying the theories discussed in unit A. Examination is continuous in this unit and is based on submitted reports and laboratory protocols. Access to individual laboratory work requires students to be well prepared which is checked randomly. Students are only given credit for laboratory work in a current term if all reports and protocols have been submitted within three weeks of the conclusion of the course. Late submissions will be graded at the earliest convenience, but no later than the next course opportunity. Module KEGAOO, Organic Chemistry Upon completion of the module students shall be able to - name organic compounds according to the IUPAC nomenclature rules with a straight or monocyclic main chain with up to two functional groups, four substituents and two chiral carbon atoms, - name some common organic compounds with common names (see hand-out), - explain simple correspondence between the structure of an organic molecule and physical properties such as melting point, boiling point, acid or base properties, - describe molecules with different representational structures wedged and dashed, formula, Newman and Fischer projections), - make conformational analyses of substituted butane and disubstituted cyclohexanes, - apply the mechanism of electrophilic addition to alkenes and alkynes, - apply the SN1 and SN2 mechanisms of nucleophilic substitution and the E1 and E2 mechanisms for elimination of alkyl halides, - apply Hückels rule to determine if a compound is aromatic, - explain the mechanism of electrophilic aromatic substitution, - name some oxidation aids for alcohol and aldehyde oxidation. - apply the mechanism for reducing aldehydes, ketones, and carboxylic acids with hydrid reagents, - describe the production of Grignard compounds and apply the mechanism of their reaction with aldehydes and ketones, - apply the mechanism of hydrolysis of esters, amides, and nitriles, - perform simple syntheses and use the unit operations extraction, filtering, recrystallisation, and destillation in small-scale laboratory work. The module comprises two units which are examined separately.

4 A. Theory, 4.5 ECTS credits: - brief overview of chemical bonding - the structure of carbon compounds and their reactions, grouped according to functional group and appropriate mechanisms of reaction. The classes of compounds treated are alkanes, alkenes, alkynes, aromatics, alkyl halides, alcohols, esters, carbonyl compounds, and amines. The reactions treated are addition, substitution, elimination, and rearrangement. Special emphasis is put on stereochemistry and molecular representational structures, - the IUPAC's nomenclatur system for common molecules of different compound classes. B. Laboratory Work, 3 ECTS credits: -safety and hazard regulations - simple syntheses including the unit operations operations extraction, filtering, recrystallisation, and destillation - thin layer chromatography and melting-point estimation - report writing and routines for laboratory notes. The laboratory unit requires mandatory attendance. Examination is continuous in this unit and is based on submitted reports and laboratory protocols. Access to individual laboratory sessions requires students to be well prepared which is checked randomly. Students are only given credit for laboratory work in a current term if all reports and protocols have been submitted within three weeks of the conclusion of the course. Late submissions will be graded at the earliest convenience, but no later than the next course opportunity. Module KEGABB, Biochemistry Upon completion of the course, students should be able to: - give an account of pro- and eukaryotic cell structures and their function - give an account of the physical-chemical properties of amino acids and identify the amino acids on the basis of their structure - give an account of the structure and function of the macromolecular groups: proteins, nucleic acids, carbohydrates, and lipids - describe the structure, properties, and function of biological membranes and give an account of different types of transport across the biological membranes - describe some common biochemical methods of analysis and purification - give an account of basic concepts in enzymatic catalysis and enzyme kinetics, and use the measuring data to determine kinetic parameters for a reaction according to Michaelis-Menten kinetics - give an account of the general mechanisms of replication and transcription of DNA and of processing and translating RNA - explain the relation between the structure of a gene and the function of proteins - describe some gene-technological methods - give an account of the reactions in the glycolysis, gluconeogenesis, glycogenesis, glycogenolysis, citric acid cycle, and the mitochondrial electron transport chain - explain the principles of substrate-level phosphorylation and oxidative phosphorylation - describe human physiological intermediary metabolism from the perspective of carbohydrates - conduct basic laboratory work in an adequate and safe manner, and do basic risk- and safety assessments - use a scientific approach to document and present, orally and in writing, the purpose, execution, and results of experimental work. The module comprises two units which are examined separately. A. Theory, 4.5 ECTS cr - pro- and eukaryotic cell structures - the macromolecules proteins, carbohydrates, lipids, and nucleic acids - biochemical separation methods - enzymes and enzyme kinetics

5 - the flow of genetic information with replication, transcription, and translation - DNA-technology - metabolism and energy conversion with glycolysis, gluconeogenesis, glycogenesis, glycogenolysis, citric acid cycle, the mitochondrial electron transport chain, and oxidative phosphorylation. B. Laboratory Work, 3 ECTS cr In the laboratory unit, the students work on laboratory assignments that connect to theoretical knowledge from the previous unit, such as enzyme kinetics, analytical and preparative separation techniques and DNA-technology. Participation in the laboratory assignments is mandatory. Examination is continuous in this unit and is based on submitted reports and laboratory protocols. Access to individual laboratory work requires students to be well prepared which is checked randomly. Students are only given credit for laboratory work in a current term if all reports and protocols have been submitted within three weeks of the conclusion of the course. Late submissions will be graded at the earliest convenience, but no later than the next course opportunity. Reading List See separate document. Examination Examination of theoretical components is in the following forms: Modules KEGAIK and KEGAKB Continuous assessment in the form of voluntary hand-in assignments or a voluntary minor test and a final written exam. The final grade is a total appraisal of the continuous assessment and the final exam. The number of examination opportunities is limited to three per academic year. Module KEGAOO Continuous assessment in the form of voluntary minor test and a final written exam. The final grade is a total appraisal of the continuous assessment and the final exam. The number of examination opportunities is limited to three per academic year. Module KEGABB Continuous assessment in the form of voluntary minor test and a final written exam. The final grade is a total appraisal of the continuous assessment and the final exam. The number of examination opportunities is limited to three per academic year. Grades One of the grades Fail (U), Pass (G), or Distinction (VG) is awarded in the examination of the course. Quality Assurance Follow-up relating to learning conditions and goal-fulfilment takes place both during and upon completion of the course in order to ensure continuous improvement. Course assessment is based on student views and experiences as reported in written course evaluations and/or group discussions. Students will be informed of the result of the evaluation and of the measures to be taken. Course Certificate A course certificate will be provided upon request. Additional Information Students who enrolled before 1 July 2007 will complete their studies in accordance with the requirements of the earlier admission. Upon completion students may request degree and course certificates to be issued under the current ordinance if they meet its requirements. KOO110, KOO120, KOO130, KOO140, KIK110, KIK120, KIK121, KOK110, KOK120, KOK130, KOK140, KBK110, KBK120, KEGAKB, KEGAIK, KEGABB, KEGAOO or KEGAAK cannot be included in the same

6 degree programme as KEGAH0. The local regulations for studies at the Bachelor s and Master s levels at Karlstad University stipulate the obligations and rights of students and staff. Karlstads universitet Karlstad, Sweden Tel Fax information@kau.se