A SURVEY OF ORGANIC CHEMISTRY CHEMISTRY 1315 TuTr 9:35-10:55 am, Boggs B6

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1 GEORGIA INSTITUTE OF TECHNOLOGY School of Chemistry and Biochemistry Spring 2004 A SURVEY OF ORGANIC CHEMISTRY CHEMISTRY 1315 TuTr 9:35-10:55 am, Boggs B6 Instructor: Marcus Weck Office: Boggs 3-85 Phone: (404) marcus.weck@chemistry.gatech.edu Office Hours: Tuesday and Thursday 8-9:35am, and by appointment Teaching Assistants: Warren Gerhardt (gtg132d@mail.gatech.edu) Office Hours Boggs 3-58: Monday 11am-12pm MaryNell Higley (marynellhigley@hotmail.com) Office Hours Boggs 3-58: Tuesday 11am-12pm Open Discussion Sections: Tuesday 6-7pm; Boggs 2-28 Thursday 6-7pm; Boggs 2-28 A. Course Description Greetings! This course is intended to introduce you to the major concepts in organic chemistry and prepare you for the biochemistry classes you will face in the coming semesters and in your research. THIS COURSE DOES NOT FULFILL THE ORGANIC CHEMISTRY REQUIREMENTS OF THE CHEMICAL ENGINEERING AND THE BIOLOGY CURRICULA AT GEORGIA TECH!!!! IT DOES NOT SATISFY THE ADMISSION REQUIREMENTS FOR MOST MEDICAL SCHOOLS PRE-MED STUDENTS, AND THOSE IN ChE AND BIOL MUST TAKE CHEM B. Textbook The following textbook has been ordered by the bookstore. Robert J. Ouellette, Organic Chemistry, A Brief Introduction. Second Edition. Prentice Hall. ISBN: I will distribute several hand-outs which can be found on the web several days before the lecture.

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3 C. Requirements and Grading Weekly assignments/problem sets: There will be eight (8) homework assignments/problem sets that will be worth 100 points each, for a total of 800 points. These assignments are due at the beginning of class (for due dates, see below). The solutions will be posted on the bulletin board outside my office and on our course Website after you've handed in your assignment for that week. Penalties for late submission: 1 day - 50% off; 2 days - 75% off; more than two days - no credit. You may work in groups of up to three persons on the homework assignments. Exams: There will be four "midterm" exams for a total of 600 points, plus a final exam. Each midterm exam is worth 150 points, and the final is worth 350 points, for a grand total of 950 points. While you MUST take all five exams, you may choose to "drop" the exam on which you received the fewest points at the end of the semester before grades are due and it will not be counted toward your final course grade (a grand total of 800 points will be graded). NOTE: YOU MAY NOT DROP THE FINAL EXAM!!!!! There will be no make-up exams for the midterm exams! Grading: Homework assignments (800 points) 40% Three written, in-class exams, plus the final (800 points) 40% Class participation (400 points) 20% Tentative Grading Scheme: A B C D F Important note: Attendance in lectures is mandatory! D. General All students who may need special accommodations for any sort of disability, or know they will have to schedule a make-up exam because of a religious holiday, please see me during my office hours or contact me after class. You must provide a letter of documentation from the Disabled Students Services Office for verification purposes well in advance of the time that the special accommodation is required. No cellular phones are allowed in class. Since the class is at 9:35 am, feel free to bring a cup (or a pot) of coffee. E. Academic Honesty

4 It is expected that all students are aware of their responsibilities under the Georgia Tech Academic Honor Code, which will be strictly adhered to in class. Students are encouraged to work together on problem sets, however, the solutions that are turned in must be the work of each individual student. No teamwork during exams! All information required for exams will be supplied. The use of programmable calculators during exams is not allowed. For re-grading, you have to hand in your homework or exam within one week after the distribution. You have to include a written statement why a question should be re-graded. F. Tentative Dates Homework assignments: Handed-out Due (in class) Homework # Homework # Homework # Homework # Homework # Homework # Homework # Homework # Exams: First Exam: :35 10:55am Boggs B6A Second Exam: :35 10:55am Boggs B6A Third Exam: :35 10:55am Boggs B6A Fourth Exam: :35 10:55am Boggs B6A Final: :00-10:50am Boggs B6A

5 G. Course Schedule (Tentative) Lecture Topic Tentative Dates Suggested Readings Introduction I. Structure and Properties of Organic Compounds Chapters 1 and 2 Atomic Structures and Properties Bonding Charges and Resonance Structures Shapes of Orbitals and Molecules Functional Groups Nomenclature Basic Reactions Basic Mechanisms Chemical Equilibrium and Reaction Rates II. Alkanes, Alkenes, and Alkynes Chapters 3 and 4 Nomenclature of Alkanes Properties Oxidations and Halogenation Nomenclature of Alkenes and Alkynes Stereochemistry of Alkenes and Alkynes Reactions of Alkenes and Alkynes Alkenes and Alkynes in Nature First Exam III. Aromatic Compounds Chapter 5 Benzene Aromaticity Reactions on Aromatic Compounds IV. Stereochemistry Chapter 6 ` Molecule Configuration Chirality Optical Activity Stereogenic Centers Synthesis and Reactions of Chiral Compounds V. Substitutions and Eliminations Chapter 7 Nucleophilic Substitutions Elimination Second Exam VI. Functional Groups I Chapters 8-10

6 Alcohols Nomenclature and Properties of Alcohols Reactions of Alcohols Ethers Nomenclature and Properties of Ethers Reactions of Ethers Epoxides The Carbonyl Group Nomenclature and Properties of Aldehydes and Ketones Reactions of Aldehydes and Ketones No Class (Midterm Recess) Third Exam VII. Carbohydrates Chapter 11 Monosaccharides Disaccharides Polysaccharides VIII. Functional Groups II Chapters Carboxylic Acids and Esters Nomenclature and Properties of Carboxylic Acids and Esters Reactions of Carboxylic Acids and Esters Lipids Fatty Acids Glycerols Biological Membranes Amines and Amides Nomenclature and Properties of Amines and Amides Reactions of Amines and Amides Fourth Exam IX. Amino Acids, Peptides and Proteins Chapter 15 Introduction Amino Acids Peptides Proteins X. Nucleic Acids Chapter 16 DNA, the Basis of Life Nucleotides Properties of DNA Genetic Code and Information Final