CHEM CHEMISTRY. Note: See beginning of Section H for abbreviations, course numbers and coding.

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1 CHEM CHEMISTRY Valid WHMIS (Workplace Hazardous Materials Information System) certification is required for all students who wish to take CHEM laboratory courses. WHMIS certification workshops will be provided. Please contact the Chemistry Department at least two weeks prior to the start of each term for schedule. Note: See beginning of Section H for abbreviations, course numbers and coding. CHEM 1001 General Chemistry I (3C 1T) An introduction to atoms and molecules, chemical equations and reactions, the periodic table, the electronic structure of atoms, and chemical bonding as well as an introduction to organic chemistry including structure and bonding, functional groups, isomers, reactions, polymers and spectroscopy. An adequate high school background in maths, physics and chemistry is required. CHEM 1006 General Chemistry Laboratory, Part I Topics include: qualitative analysis, investigation of inorganic reactions, a simple organic synthesis and construction of bonding and geometry models of organic and inorganic species. WHMIS certification required (see beginning of Chemistry Courses section for details). Co-requisite: CHEM CHEM 1012 General Chemistry II (3C 1T) An introduction to gases, thermochemistry, rates of reaction, chemical equilibrium, spontaneity of reactions, intermolecular forces, reactions in aqueous solution, acids and bases, acid-base equilibria, solubility equilibria, redox reactions, and electrochemistry. Restricted to students in the Faculty of Science and those in other faculties who intend to take more than two main stream courses in chemistry. Prerequisite: Chem 1001 (C or higher); Pre or Co-requisite: Math CHEM 1017 General Chemistry Laboratory, Part II Topics include: ideal gases, heats and rates of reactions, chemical equilibria, acid-base and solubility equilibria, redox titrations, voltaic cells and electrolysis. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1006; Co-requisite: CHEM CHEM 1553 Hitchhiker s Guide to Chemistry This course is intended for Arts or other students not in Science and Engineering and who have little or no chemistry background. The course will cover the basic principles and concepts of atoms and molecules, chemical bonding, acids and bases, and organic compounds. The material will be applied to the understanding of everyday chemistry including proteins, carbohydrates, polymers, acid rain, etc. This course cannot be used as a substitute for any other first level Chemistry course. CHEM 1801 General Chemistry - Basic Concepts, Organic Chemistry and Biochemistry (3C 1T) Intended primarily for non-science students who have insufficient chemistry background. Covers the nature of atoms and molecules, the periodic table, chemical bonds, stoichiometry, valence and acid-base reactions as well as classification and reactions of organic compounds, organic polymers, proteins, carbohydrates, nucleic acids, and steroids. CHEM 1882 General Applied Chemistry 5 ch (3C 1T 3L) Intended primarily for Engineering (other than Chemical) students. Building on examples from environmental chemistry, polymers, fuel cells and corrosion, this course covers chemical material properties, solutions & solubility, kinetics & equilibrium, acids & bases, thermodynamics and 12/9/ of 9

2 electrochemistry. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: 70% in Grade 12. Chemistry or CHEM 1801 ("D" grade not acceptable). CHEM 1882 General Chemistry-Physical and Inorganic Chemistry 5 ch (3C 1T 3L) Intended primarily for non-science students who require an introduction to physical and inorganic chemistry. Covers chemical equilibria, electrochemistry, thermodynamics and chemical kinetics. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1801 ("D" grade not acceptable) or 70% in Grade 12 Chemistry. CHEM 2002 Introductory Quantum Chemistry 4 ch (3C 1L) Molecular symmetry. Basic quantum theory and solutions for simple models. The orbital (Hartree-Fock) model for molecules. The Huckel model. Selected contemporary topics. Includes a computer laboratory component. Prerequisiste: MATH Co-requisite Math 2213 or equivalent. CHEM 2111 Introductory Analytical Chemistry 5 ch (3C 3L) [W] Theory and practice, topics include concepts of acid-base, redox, precipitation and solvent extraction equilibria; sample handling and preparation; calibration techniques; error analysis and regression analysis; titrimetric and spectrophometric analysis. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1012 and CHEM 2201 Inorganic Chemistry I Periodic properties of the atoms. Bonding, structures and reactions of inorganic compounds. Prerequisite: CHEM 1012 ("D" grade not acceptable). CHEM 2222 Inorganic Chemistry II Bonding, structures and reactions of inorganic compounds. Prerequisite: CHEM 2201 ("D" grade not acceptable). CHEM 2237 Inorganic Chemistry Laboratory [W] Introduction to preparation techniques in inorganic chemistry. Emphasis on Main Group and Transition element chemistry. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017, CHEM 2201, CHEM 2416 Co-requisite: CHEM CHEM2401 Organic Chemistry for the Life Sciences This course introduces organic molecules and illustrates the principles of organic chemistry that are relevant to biological systems. This course is not equivalent to CHEM Students in the Biology- Chemistry or Chemistry programs must take CHEM Prerequisites: CHEM 1012 or CHEM ("D" grade not acceptable). CHEM 2416 Chemistry Laboratory I Introduction to experimental chemistry (Organic) Part I, with emphasis on the structure determination of organic compounds. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017 ("D" grade not acceptable). Co-requisite: Either CHEM 2401 or CHEM CHEM 2401 Organic Chemistry I An introductory course. Topics include bonding, elementary stereochemistry, optical isomerism, functional groups, structure determination, reactions of Alkenes and Alkynes. Prerequisites: CHEM 1012 or CHEM ("D" grade not acceptable). CHEM 2416 Chemistry Laboratory I 12/9/ of 9

3 Introduction to experimental chemistry (Organic) Part I, with emphasis on the structure determination of organic compounds. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017 ("D" grade not acceptable). Co-requisite: CHEM CHEM 2421 Organic Chemistry I An introductory course. Topics include bonding, elementary stereochemistry, optical isomerism, functional groups, structure determination, reactions of Alkenes and Alkynes. Prerequisites: CHEM 1012 or CHEM ("D" grade not acceptable). CHEM 2422 Organic Chemistry II A continuation of CHEM Topics include stereochemistry, alkyl halides, nucleophilic reactions, alcohols, ethers, substitution and elimination reactions and their synthetic utility. Prerequisite: CHEM 2421 ( D grade not acceptable). CHEM 2422 Organic Chemistry II A continuation of CHEM Topics include stereochemistry, alkyl halides, nucleophilic reactions, alcohols, ethers, substitution and elimination reactions and their synthetic utility. Prerequisite: CHEM 2401 ("D" grade not acceptable). Comment [W1]: Change to prerequisite to reflect renumbering of CHEM2421 CHEM 2601 Chemical Thermodynamics The three laws of thermodynamics, thermochemical calculations, chemical equilibria, introduction to phase rule. Prerequisites: MATH 1013 or equivalent, CHEM 1012; Co-requisite: MATH 2003 or equivalent. CHEM 2621 Electrochemistry and Chemical Kinetics Elementary electrochemistry, electrochemical cells, electrolysis, electromotive forces, applications of EMF measurements. Reaction kinetics and mechanisms, uni- bi-, and termolecular reactions, catalysis, enzyme catalysis, chain reactions, reaction dynamics, steric effects and transition state theory. Prerequisite: CHEM 2601 (or CHE 2123 for Chemical Engineering students only) ; Co-requisite: MATH 2003 or equivalent. CHEM 2622 Electrochemistry and Chemical Kinetics Elementary electrochemistry, electrochemical cells, electrolysis, electromotive forces, applications of EMF measurements. Reaction kinetics and mechanisms, uni- bi-, and termolecular reactions, catalysis, enzyme catalysis, chain reactions, reaction dynamics, steric effects and transition state theory. Prerequisite: CHEM 2601 (or CHE 2123 for Chemical Engineering students only) ; Co-requisite: MATH 2003 or equivalent. CHEM 2637 Chemistry Laboratory II [W] 12/9/ of 9

4 Introduction to experimental chemistry (Physical) Part II. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017 ("D" grade not acceptable). Co-requisite: CHEM CHEM 2637 Chemistry Laboratory II [W] Introduction to experimental chemistry (Physical) Part II. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017 ("D" grade not acceptable). Co-requisite: CHEM CHEM 2857 Organic Chemistry Laboratory A Laboratory course for non-chemistry Majors designed to accompany CHEM Approximately 30 hours of laboratory work are involved. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2416; Pre- or Co-requisite: CHEM CHEM 2886 Analytical Chemistry Laboratory for Chemical Engineers This course teaches the basic techniques and concepts of chemical analysis. Covers handling skills, titration methods (conventional and potentiometric) and spectrophotometry (UV - visible, and flame atomic absorption/emission). WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM 1012 and CHEM CHEM 3001 Introductory Quantum Chemistry 4 ch (3C 1L) Molecular symmetry. Basic quantum theory and solutions for simple models. The orbital (Hartree-Fock) model for molecules. The Huckel model. Selected contemporary topics. Includes a computer laboratory component. Prerequisite: MATH 2003/2213 or equivalent. CHEM 3003 Biocomputing in Drug Design I 5 ch (3C, 3L) Introduction to biocomputing in the pharmaceutical industry. Topics include molecular modeling, rational drug design, high throughput screening and combinatorial chemistry, protein modeling and 3D bioinformatics. Course includes lectures and a computer laboratory component. Note: This course is cross-listed as CS Prerequisites: CHEM 1012 and BIOL 1012, or permission of instructor. CHEM 2421 or BIOL 2033 are recommended. CHEM 3003 Biocomputing in Drug Design I 5 ch (3C, 3L) Introduction to biocomputing in the pharmaceutical industry. Topics include molecular modeling, rational drug design, high throughput screening and combinatorial chemistry, protein modeling and 3D bioinformatics. Course includes lectures and a computer laboratory component. Note: This course is cross-listed as CS Prerequisites: CHEM 1012 and BIOL 1012, or permission of instructor. CHEM 2401 or BIOL 2033 are recommended. CHEM 3132 Intermediate Analytical Chemistry 5 ch (3C 3L) Principles and applications of both equilibrium-based and basic instrumental methods of analysis. Topics include non-aqueous and complexometric titrations, analytical separations, potentiometry, analytical spectrophotometry, gas chromatography, elementary chemometrics, sample preparation and method development. Experiments are designed to illustrate the application of these methods in the analysis of real samples and in the study of analytical principles. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM /9/ of 9

5 CHEM 3202 Inorganic Chemistry III Covers transition metals and introduction to organometallic chemistry. Prerequisites: CHEM 2222 and CHEM CHEM 3201 Inorganic Chemistry III Covers transition metals and introduction to organometallic chemistry. Prerequisites: CHEM 2222 and CHEM CHEM 3222 Inorganic Chemistry IV Selected aspects of main group inorganic chemistry emphasizing periodic trends. Prerequisites: CHEM CHEM 3221 Inorganic Chemistry IV Selected aspects of main group inorganic chemistry emphasizing periodic trends. Prerequisites: CHEM CHEM 3236 Inorganic Chemistry Laboratory (3L)[W] Advanced preparative techniques in inorganic chemistry. Applications of IR, NMR and UV-VIS spectroscopy. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM CHEM 3416 Organic Chemistry Laboratory II Functional group transformations such as alcohols to ketones, acids to esters, etc. via a variety of synthetic methods will be performed. IR, NMR and other spectroscopic methods will be applied to product characterizations and/or structure elucidations. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM Co-requisite: CHEM 3421 or CHEM Note: Credit can be obtained for only one of CHEM 2857 or CHEM CHEM 3421 Organic Chemistry III Covers aldehydes, ketones, carboxylic acid derivatives, enolates, carbanion chemistry and organic synthesis. Prerequisite: CHEM CHEM 3401 Organic Chemistry III Covers aldehydes, ketones, carboxylic acid derivatives, enolates, carbanion chemistry and organic synthesis. Prerequisite: CHEM CHEM 3416 Organic Chemistry Laboratory II Functional group transformations such as alcohols to ketones, acids to esters, etc. via a variety of synthetic methods will be performed. IR, NMR and other spectroscopic methods will be applied to product characterizations and/or structure elucidations. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM Co-requisite: CHEM 3401 or CHEM Note: Credit can be obtained for only one of CHEM 2857 or CHEM CHEM 3421 Organic Chemistry IV Covers spectroscopic aids, aromaticity, electrophilic aromatic substitution, alicyclic molecules, ethers, epoxides, alcohols and structure determination. Prerequisite: CHEM CHEM 3422 Organic Chemistry IV 12/9/ of 9

6 Covers spectroscopic aids, aromaticity, electrophilic aromatic substitution, alicyclic molecules, ethers, epoxides, alcohols and structure determination. Prerequisite: CHEM CHEM 3503 Medicinal Chemistry I (A) [W] Structure, properties and chemistry of nucleic acids (DNA and RNA). Unusual DNA structures. Modern probes of DNA structure, DNA binding and cleaving agents, protein-dna interactions, and other aspects of DNA recognition. Chemical mutagens and carcinogenicity. The chemical aspects of modern biochemistry tools (synthesis, sequencing, cloning, etc...) will also be covered. Prerequisite: BIOL Co-requisites: CHEM 3421 or CHEM CHEM 3503 Medicinal Chemistry I (A) [W] Structure, properties and chemistry of nucleic acids (DNA and RNA). Unusual DNA structures. Modern probes of DNA structure, DNA binding and cleaving agents, protein-dna interactions, and other aspects of DNA recognition. Chemical mutagens and carcinogenicity. The chemical aspects of modern biochemistry tools (synthesis, sequencing, cloning, etc...) will also be covered. Prerequisites: BIOL 2033 and BIOL Co-requisites: CHEM 3401 or CHEM Comment [W2]: Removal of BIOL 2043 prerequisite from CHEM 3503 CHEM 3513 Medicinal Chemistry Seminars Selected Topics in Medicinal Chemistry. Prerequisite: CHEM3421. CHEM 3523 Medicinal Chemistry II (A) [W] Protein structure: from amino acids to multi-subunit entities. Overview of protein function. Probes for protein structure. Molecular recognition of proteins. Principles of enzymology. The organic chemistry of enzyme catalysis. Chemical aspects of modern protein chemistry tools (sequencing, synthesis, etc.). Protein engineering, catalytic antibodies, ribozymes and catalytic RNA. Prerequisites: BIOL 2033, and either CHEM 3421 or CHEM CHEM 3513 Medicinal Chemistry Seminars Selected Topics in Medicinal Chemistry. Prerequisite: CHEM3401. Comment [W3]: Removal of BIOL 2043 prerequisite from CHEM 3523 CHEM 3601 Molecular Spectroscopy Molecular Spectroscopy, electronic, vibrational and rotational spectra of diatomic and polyatomic molecules. Radiative and non-radiative transitions. Nuclear magnetic resonance and electron-spin resonance spectroscopy. Prerequisite: CHEM CHEM 3523 Medicinal Chemistry II (A) [W] Protein structure: from amino acids to multi-subunit entities. Overview of protein function. Probes for protein structure. Molecular recognition of proteins. Principles of enzymology. The organic chemistry of enzyme catalysis. Chemical aspects of modern protein chemistry tools (sequencing, synthesis, etc.). Protein engineering, catalytic antibodies, ribozymes and catalytic RNA. Prerequisites: BIOL 2033, BIOL 2043 and either CHEM 3401 or CHEM Comment [W4]: Change in term offered CHEM 3616 Physical Chemistry Laboratory (Molecular Spectroscopy) [W] Spectroscopic techniques and applications in the ultra-violet, visible, infrared and nuclear magnetic resonance regions. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM Co-requisite: CHEM CHEM 3622 Statistical Thermodynamics and Theories of Reaction Rates 12/9/ of 9

7 Probability distributions, ensembles, Maxwell-Boltzman distribution, partition functions, hard sphere collision theory, potential energy surfaces, transition state theory, reaction dynamics. Prerequisites: Math 2003/2013 or equivalent, CHEM 2621, CHEM CHEM 3602 Molecular Spectroscopy Molecular Spectroscopy, electronic, vibrational and rotational spectra of diatomic and polyatomic molecules. Radiative and non-radiative transitions. Nuclear magnetic resonance and electron-spin resonance spectroscopy. Co-requisite: CHEM CHEM 3616 Physical Chemistry Laboratory (Molecular Spectroscopy) [W] Spectroscopic techniques and applications in the ultra-violet, visible, infrared and nuclear magnetic resonance regions. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM Corequisite: CHEM CHEM 3801 Chemistry in Pulp and Paper [W] This course treats the chemistry of wood and different pulping processes with emphasis on the general chemistry of the pulping and bleaching processes and the analytical methods as applied to wood and pulp. The students will acquire the chemistry background for the processes and technologies of the pulp and paper industry. Prerequisites: CHEM 2421 or CHE 2401, and CHEM CHEM 3621 Statistical Thermodynamics and Theories of Reaction Rates Probability distributions, ensembles, Maxwell-Boltzman distribution, partition functions, hard sphere collision theory, potential energy surfaces, transition state theory, reaction dynamics. Prerequisite: Math 2003/2013 or equivalent, CHEM 2622, CHEM CHEM 3886 Physical Chemistry Laboratory for Chemical Engineers This course consists of experiments in chemical kinetics and electrochemistry. Topics include order of reaction, activation energies, reaction mechanisms, solution conductivities, enzyme kinetics and fast reaction kinetics. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2621 CHEM 3801 Chemistry in Pulp and Paper [W] This course treats the chemistry of wood and different pulping processes with emphasis on the general chemistry of the pulping and bleaching processes and the analytical methods as applied to wood and pulp. The students will acquire the chemistry background for the processes and technologies of the pulp and paper industry. Prerequisites: CHEM 2401 or CHE 2401, and CHEM CHEM 3886 Physical Chemistry Laboratory for Chemical Engineers This course consists of experiments in chemical kinetics and electrochemistry. Topics include order of reaction, activation energies, reaction mechanisms, solution conductivities, enzyme kinetics and fast reaction kinetics. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2622 CHEM 3897 Organic Chemistry Laboratory for Chemical Engineers 1 ch (3L) This course provides experience in the basic experimental techniques commonly used in organic chemistry. It illustrates several reaction types in organic chemistry and provides examples of functional group transformations. WHMIS certification required (see beginning of Chemistry Courses section for details). CHEM 3903 Work Term Report I CR 12/9/ of 9

8 A written report on the scientific activities of the work term. A component of the grade will be the employer s evaluation of the student. (Students must have a GPA of 3.2 or better for CHEM COOP program.) CHEM 4000 Senior Research Projects 6 ch [W] CHEM 4000 is a project based course where students conduct research under the supervision of a chosen faculty member. Students must be in their final year of any Chemistry program or in any interdepartmental program involving Chemistry (including General Science) and must have a CGPA of 3.0 or better. Students are encouraged to contact potential supervisors and must apply in writing to the CHEM 4000 coordinator by August 15 of that year. Upon consideration by the potential research supervisors, successful applicants will be notified during the first week of the Fall term. A minimum of at least 6 scheduled hours per week is required and one seminar presentation will be required at the end of the academic year. WHMIS certification required (see beginning of Chemistry Courses section for details). Pre- or Co-requisite: 4th year level lecture courses in selected project area. CHEM 4003 Biocomputing in Drug Design II 4 ch (3C 2L) A follow-up of CHEM Topics include pharmacophore perception, solvation models, free-energy calculations, multivariate statistics, genetic algorithms, principal component analysis, virtual drug libraries, chemical diversity and cheminformatics. Course includes lectures and computer laboratory component. Note: This course is cross-listed as CS Prerequisite: CHEM/CS CHEM 4007 Advanced Synthetic Methods Laboratory (3L) Further work in the inorganic and organic chemistry laboratory. Experimental projects will provide students with an opportunity to do further work in previously encountered topics, and to gain practical experience in more advanced topics. Some emphasis will be placed on the role of chemical research. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM3236 and CHEM3416 or Departmental approval. CHEM 4013 Intermediate Quantum Chemistry 4 ch (3C 1L) The spin-restricted and unrestricted Hartree-Fock methods, and their algebraic analogs. Density functional theory. Rayleigh Schrodinger perturbation theory. A sampling of advanced methods. The laboratory component includes practical molecular calculations. Prerequisite: CHEM CHEM 4013 Intermediate Quantum Chemistry 4 ch (3C 1L) The spin-restricted and unrestricted Hartree-Fock methods, and their algebraic analogs. Density functional theory. Rayleigh Schrodinger perturbation theory. A sampling of advanced methods. The laboratory component includes practical molecular calculations. Prerequisite: CHEM CHEM 4017 Advanced Instrumental Methods Laboratory (3L) Further experimental work in the analytical and physical chemistry disciplines. Experimental studies will provide students with an opportunity to do further work in previously encountered topics, and to gain practical experience in more advanced topics. Some studies may involve original chemical research. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM3132 and CHEM3616 or Departmental approval. CHEM 4111 Instrumental Analytical Chemistry I (2C 2L) A coordinated laboratory-lecture course to introduce the principles of instrumental analysis, operational aspects of analytical spectroscopy and chromatography. The laboratory component is designed to study the operation, application and limitation of selected methods which will form the basis of optimization and method development. Real materials are used to illustrate the common sample preparation 12/9/ of 9

9 methods. Students will use spreadsheet, word processor and program language extensively for data analysis and presentation. Prerequisites: CHEM 3132 and CHEM CHEM 4112 Advanced Analytical Chemistry Advanced Topics in Analytical Chemistry. Prerequisite: Departmental approval. CHEM 4222 Advanced Inorganic Chemistry Advanced topics in Inorganic Chemistry. Prerequisite: Departmental approval. CHEM 4422 Advanced Organic Chemistry Advanced topics in organic chemistry. Prerequisite: Departmental approval. CHEM 4622 Advanced Physical Chemistry Advanced topics in physical chemistry. Prerequisite: Departmental approval. 2 ch (2C) 2 ch (2C) 2 ch (2C) 2 ch (2C) CHEM 4832 Pulp and Paper Testing (3L) [W] This course treats the chemical and physical testing methods related to pulp, paper and their manufacturing processes. The student will acquire a general knowledge of the testing methods frequently used in the Pulp and Paper Industry. Prerequisites: CHEM 2880 or 2111/3132/4801. CHEM 4903 Work Term Report II CR A written and oral report on the scientific activities of the work term. A component of the grade will be the employer s evaluation of the student. (Students must have a GPA of 3.2 or better for CHEM CO-OP program.) CHEM 4909 Directed Studies in Advanced Chemistry Students may pursue directed studies in specific areas and topics related to chemistry. These studies may involve any of the chemistry disciplines. The content and process of each directed study will be determined through negotiation between a student and the supervising faculty member(s). Departmental approval is also required. CHEM 4919 Directed Studies in Advanced Chemistry Students may pursue directed studies in specific areas and topics related to chemistry. These studies may involve any of the chemistry disciplines. The content and process of each directed study will be determined through negotiation between a student and the supervising faculty member(s). Departmental approval is also required. 12/9/ of 9