Ion chromatography. Ion chromatography

Transcription

1 Ion chromatography Ion chromatography -

2 Contents Professional IC Systems 850 Professional IC Professional IC 850 introduction IC. 11 Professional IC ProfIC Systems How to choose the right ProfIC system IC. 13 «ProfIC 1 Cation» Professional IC system for automated ion chromatography IC. 14 «ProfIC 2 Cation» Professional IC system with inline ultrafiltration IC. 15 Metrohm inline ultrafiltration and dialysis IC. 16 «ProfIC 3 Cation» Professional IC system with inline dialysis IC. 17 «ProfIC 4 Cation» Professional IC system with inline dilution IC. 18 «ProfIC 5 Cation» Professional IC system with variable sample preconcentration IC. 19 «ProfIC 6 Cation» Professional IC system with inline dilution and ultrafiltration IC. 20 «ProfIC 7 Cation» Professional IC system with inline dilution and dialysis IC. 21 «ProfIC 8 Cation» Professional IC system with inline sample preconcentration and matrix elimination IC. 22 «ProfIC 9 Cation» Professional IC system for trace analysis with inline calibration, sample preconcentration and matrix elimination IC. 23 «ProfIC 15 Cation» Professional IC system for partial loop injection IC. 24 «ProfIC 1 Anion» Professional IC system for automated ion chromatography IC. 25 Reproducibility of the suppression IC. 26 Sequential suppression IC. 27 «ProfIC 2 Anion» Professional IC system with inline ultrafiltration IC. 28 «ProfIC 3 Anion» Professional IC system with inline dialysis IC. 29 «ProfIC 4 Anion» Professional IC system with inline dilution IC. 30 «ProfIC 5 Anion» Professional IC system with variable sample preconcentration IC. 31 «ProfIC 6 Anion» Professional IC system with inline dilution and ultrafiltration IC. 32 «ProfIC 7 Anion» Professional IC system with inline dilution and dialysis IC. 33 «ProfIC 8 Anion» Professional IC system with inline sample preconcentration and matrix elimination IC. 34 «ProfIC 9 Anion» Professional IC system for trace analysis with inline calibration, sample preconcentration and matrix elimination IC. 35 «ProfIC 10 Anion» Professional IC system with inline sample preconcentration, matrix elimination and matrix neutralisation IC. 36 «ProfIC 11 Anion» Professional IC system for trace analysis with inline calibration, sample preconcentration and matrix elimination IC. 37 «ProfIC 12 Anion» Professional IC gradient system IC. 38 «ProfIC 15 Anion» Professional IC system for partial loop injection IC. 39 «ProfIC 1 AnCat» Professional IC system for automated ion chromatography IC. 40 «ProfIC 2 AnCat» Professional IC system with inline ultrafiltration IC. 41 «ProfIC 15 AnCat» Professional IC system for partial loop injection IC IC

3 Contents Professional IC Instruments 850 Professional IC Professional IC Instrument Introduction IC. 43 Professional IC Detector 850 Professional IC Detector idetector IC Professional UV/VIS Detector IC. 44 Professional IC Cation Overwiew on 850 Professional IC instruments IC Professional IC Cation IC Professional IC Cation Prep 1 IC Professional IC Cation Prep 2 IC. 46 Professional IC Anion 850 Professional IC Anion IC Professional IC Anion MSM-HC IC Professional IC Anion MCS IC Professional IC Anion MSM-HC MCS IC Professional IC Anion MCS Prep 1 IC Professional IC Anion MSM-HC MCS Prep 1 IC Professional IC Anion MCS Prep 2 IC Professional IC Anion MSM-HC MCS Prep 2 IC Professional IC Anion MCS Prep 3 IC Professional IC Anion MSM-HC MCS Prep 3 IC. 49 Professional IC Gradient 850 Professional IC Cation LP Gradient IC Professional IC Anion MSM-HC LP Gradient IC Professional IC Anion MCS LP Gradient IC Professional IC Anion MSM-HC MCS LP Gradient IC Professional IC Cation Gradient IC Professional IC Anion MSM-HC Gradient IC Professional IC Anion MCS Gradient IC Professional IC Anion MSM-HC MCS Gradient IC. 51 Professional IC AnCat 850 Professional IC AnCat non-suppressed IC Professional IC AnCat IC Professional IC AnCat MCS IC Professional IC AnCat MSM-HC MCS IC. 52 Professional IC Extension Modules Overwiew on 872 Extension Modules IC Extension Module IC Pump IC Extension Module IC Module IC Extension Module Sample Prep IC Extension Module Liquid Handling IC Extension Module Suppression IC Extension Module Suppression MCS IC IC

4 Contents Compact IC Instruments Compact IC Instruments Compact IC Instruments Introduction IC. 57 Overwiew on Compact IC Instruments IC. 58 Compact IC pro Instruments 881 Compact IC pro Cation IC Compact IC pro Anion IC Compact IC pro Anion MCS IC. 59 Compact IC plus Instruments 882 Compact IC plus Cation IC Compact IC plus Anion IC Compact IC plus Anion MCS IC. 60 Basic IC plus Instruments 883 Basic IC plus IC Basic IC plus Package IC IC

5 Contents Additional IC Componets Alternative IC Components Alternative IC Components Introduction IC. 63 Heatable Reactors and Column Compartments 886 Professional Reactor IC Professional Thermostat IC. 64 Data Converters 891 Professional Analog Out IC IC Compact Interface IC IC Compact Interface; MagIC Net Professional IC IC Compact Interface; MagIC Net Compact IC. 65 Electrochemical Detectors 791 VA Detector IC Advanced Bioscan IC IC

6 Contents Professional IC Hyphenated Technologies Hyphenated Systems IC Hyphenation IC. 67 IC Hyphenated Systems TitrIC 4 hyphenated IC and titration system IC. 68 TitrIC 5 hyphenated IC and titration system IC. 68 TitrIC 6 hyphenated IC and titration system IC. 69 TitrIC 7 hyphenated IC and titration system IC. 69 IC-MS and IC-ICP/MS Coupling IC. 69 Combustion IC (Mitsubishi) IC. 70 MultiTek Combustion IC (230 V) IC. 70 MultiTek Combustion IC (110 V) IC. 70 PILS, Particle Into Liquid Sampler IC. 70 MARGA, Monitor for Aerosols and Gases in Air IC IC

7 Contents Automation in Ion Chromatography Automation IC. 72 IC Automation Introduction IC. 73 Overwiew on IC Automation IC Professional Sample Processor IC Professional Sample Processor Pump IC Professional Sample Processor Pump Injector IC IC Sample Center IC IC Sample Center cool IC Robotic Soliprep for LC IC Compact IC Autosampler IC. 76 More sample processors for IC IC.77 6 IC

8 Contents Liquid Handling in Ion Chromatography Liquid Handling Liquid handling in IC IC. 79 Liquid handling for IC 800 Dosino IC Eluent Synthesizer with one Dosino IC Eluent Synthesizer with two Dosinos IC Level Control MF (for canisters) IC Level Control MF (for bottles) IC Level Control for Inline Eluent Preparation IC Dosing Interface IC. 82 IC Equipment for dialysis IC. 83 IC Equipment for ultrafiltration IC. 83 IC Equipment for dilution IC. 83 IC Equipment for Rinsing Station to mount on Sample Processor IC. 83 IC Equipment for liquid handling with Dosino IC. 84 IC Equipment for Dosino Gradient IC. 84 IQ/OQ Kit for IC IC. 84 IC Equipment for Liquid Handling Set to PILS IC. 84 Peristaltic pump, 8-channel IC IC

9 Contents Online IC 811 Online IC Instruments 811 Online IC Process Analyzer (1 channel, 230 V) IC Online IC Process Analyzer (1 channel, 115 V) IC Online IC Process Analyzer (2 channels, 230 V) IC Online IC Process Analyzer (2 channels, 115 V) IC Compact Online IC Instruments 821 Compact Online IC Process Analyzer (230 V) IC Compact Online IC Process Analyzer (115 V) IC IC

10 Contents IC Software Professional IC Software MagIC Net 2.2 Compact CD: 1 Licence IC. 91 MagIC Net 2.2 Professional CD: 1 Licence IC. 91 MagIC Net 2.2 Multi CD: 3 Licences IC. 92 TitrIC 2.0 CD IC IC

11 Professional IC Systems 10 IC

12 Professional IC Systems 850 Professional IC Professional IC 850 introduction Intelligent Ion Chromatography The 850 Professional IC is the first professional ion chromatography system with intelligent system components that are optimally matched to one another. The way from the sample to a precise result has now become easier, as the system thinks for itself and makes logical decisions on its own. complicated calculations as well as to users who prefer «one-button operation». Any user level is possible. Innovation, flexibility and very simple operation result from the intelligence of the 850 Professional IC, the 872 Extension Modules, the 858 Professional Sample Processor and the MagIC Net software. Intelligence in the hardware of the 850 Professional IC, - ipump - idetector - ireactor - intelligent Dosino Intelligence in the MagIC Net software Intelligence in the Metrosep icolumns These are the intelligent system components that monitor and optimise all functions and, if required, will also document them in an FDA-compatible form. The configuration of the system is as simple as can be, as the components log themselves in automatically and provide the MagIC Net software with all the relevant information. The optimal operation of the 850 Professional IC and the results are monitored. If a parameter leaves the predefined range then the user is informed by or SMS. The 850 Professional IC is a sophisticated and highly efficient system and yet can be operated simply and intuitively with the MagIC Net software. This applies to experienced users and complex applications with 11 IC

13 Professional IC Systems Professional IC ProfIC Systems The «ProfIC» systems are packages of Professional IC instruments and accessories tailored to the needs of a particular group of applications. These systems feature all the necessary components required to carry out the respective application completely automatically. The main components are: Be it the determination of anions in an analytical service laboratory with a very high sample throughput or the detection of cations in the ultratrace range, such as is required in nuclear power plants, the ProfIC systems offer a custom-made solution for any ever-so-demanding application. More than 20 systems can be called up under Together with the analytical column and the software they will meet the demands of any application Professional IC Conductivity Detector Professional UV/VIS Detector Professional Sample Processor Extension Module Dosino in the appropriate versions with the corresponding accessories. Not included in the standard equipment are the column, MagIC Net, sample rack and sample vials. This ensures maximum flexibility of the systems. 12 IC

14 Professional IC Systems How to choose the right ProfIC system Find the right system for your application in a few steps! Step 1 Step 2 Matrix Step 3 Concentration Step 4 Result Anions Unloaded ppt... ppb Inline Calibration ProfIC 9 - Anion no Inline Calibration ProfIC 5 - Anion ppb... ppm Full Loop Injektion ProfIC 1 - Anion Partial Loop Injektion ProfIC 15 - Anion Moderately loaded with particles ppm... % ppb... ppm ppm... % ProfIC 4 - Anion ProfIC 2 - Anion ProfIC 6 - Anion Loaded with particles ppb... ppm ProfIC 3 - Anion Loaded with a dissolved neutral matrix Loaded with a dissolved catonic matrix ppm... % ppt... ppb ppb... ppm ppt... ppb ppb... ppm ProfIC 7 - Anion ProfIC 9 - Anion ProfIC 8 - Anion ProfIC 11 - Anion ProfIC 10 - Anion Anions with gadient ProfIC 12 - Anion Anions and cations Unloaded Full Loop Injektion ProfIC 1 - AnCat Partial Loop Injektion ProfIC 15 - AnCat Moderately loaded with particles ProfIC 2 - AnCat Cations Unloaded ppt... ppb Inline Calibration ProfIC 9 - Cation no Inline Calibration ProfIC 5 - Cation ppb... ppm Full Loop Injektion ProfIC 1 - Cation Partial Loop Injektion ProfIC 15 - Cation ppm... % ProfIC 4 - Cation Moderately loaded with particles ppb... ppm ProfIC 2 - Cation ppm... % ProfIC 6 - Cation Loaded with particles ppb... ppm ProfIC 3 - Cation ppm... % ProfIC 7 - Cation Loaded with a dissolved neutral matrix ppt... ppb ProfIC 9 - Cation ppb... ppm ProfIC 8 - Cation 13 IC

15 Professional IC Systems «ProfIC 1 Cation» Professional IC system for automated ion chromatography Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed). «ProfIC 1» safely masters all routine tasks in ion chromatography. It is simple to use and extremely reliable. Quality components guarantee very high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the MagIC Net software. «ProfIC 1» contains intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The 858 Professional Sample Processor provides for sample transfer. Numerous sample racks are available for volumes in the range ml. Ordering information ProfIC 1 - Cation «ProfIC 1 Cation» Professional IC system for automated ion chromatography Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The «ProfIC 1» system is your reliable partner, both in routine operation and for research and development. 14 IC

16 Professional IC Systems «ProfIC 2 Cation» Professional IC system with Inline Ultrafiltration Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed) with Metrohm Inline Ultrafiltration. «ProfIC 2» masters all routine tasks in ion chromatography. It is easy to use and very reliable. Quality system components guarantee very high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the intelligent MagIC Net software. «ProfIC 2» is equipped with Metrohm Inline Ultrafiltration, which reliably removes particles from the sample and protects the analytical column from particulate contamination. The lifetime of the column is increased significantly. The ultrafiltration cell is equipped with a membrane filter with a pore size of 0.2 m as standard and is suitable for samples with a light to medium particle load. Inline Ultrafiltration works fully automatically, which saves the time-consuming and expensive use of syringe filters. The ultrafiltration cell is mounted directly onto the 858 Professional Sample Processor. The bidirectional dualchannel peristaltic pump provides for sample transfer through the ultrafiltration cell and to the Professional IC system. The sample is continuously delivered at a high flow rate. This delays the formation of a filter cake and increases the working life of the membrane. Cross contamination is kept below 0.1%. Ordering information ProfIC 2 - Cation «ProfIC 2 Cation» Professional IC system with inline ultrafiltration Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x IC Equipment for ultrafiltration IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately depending on the specific application. Numerous sample racks for volumes ml are available for the 858 Professional Sample Processor. Ultrafiltration requires at least 5 ml of sample. «ProfIC 2» contains intelligent system components such as the ipump and the idetector and offers space for a total of three icolumns. The «ProfIC 2» system is your reliable partner, both for routine analysis and in research and development. 15 IC

17 Professional IC Systems Metrohm Inline Ultrafiltration and dialysis Metrohm Inline Ultrafiltration Modern ion chromatography recommends all samples to be filtered prior to injection. Separation columns with particle sizes below 10 m require absolutely particle-free sample solutions. Unfiltered solutions can increase pressure on the column that in some cases can radically reduce the lifetime of the column. Manual filtration is usually carried out by means of disposable filter cartridges with a pore size of 0.45 m or less. These become clogged very quickly, particularly with samples containing very fine particles. Sample changers with filter caps are used as an alternative. Their pore size is often larger than that of disposable filters. However, they are expensive and there is still a risk of clogging. With Metrohm Inline Ultrafiltration, which belongs to the membrane separation techniques, these problems no longer apply. The samples are placed directly on the sample rack. When the samples are processed the sample flow is channelled into the lower chamber of the ultrafiltration cell and passes along the membrane and into the waste container. In the upper chamber of the cell a peristaltic pump creates a vacuum and draws the sample solution through the ultrafiltration membrane. The filtered sample solution enters the injection loop and is then injected. Less than 20% of the original solution is removed as filtrate, the remainder flows directly into the waste container. This, together with the geometrical arrangement of the cell, virtually eliminates the formation of a filter cake that could block the membrane. Metrohm Inline Ultrafiltration is particularly suitable for samples with a light to medium load, for example drinking water, surface water, wastewater, digestion solutions, extracts. Metrohm Inline Dialysis Highly polluted samples require complex and laborious sample preparation steps before they can be analyzed. Metrohm Inline Dialysis provides a considerable rationalization of the whole process. Samples must meet just one condition: they must be liquid or be able to be brought into liquid form and they need to be largely homogeneous. Larger particles can be removed by centrifuging, if necessary. The sample solution is then dialyzed in the dialysis cell according to the method patented by Metrohm (European Patent , US Patent 5,861,097). Due to this special «Inline Stopped- Flow Dialysis» method a virtually complete dialysis is obtained. This means that the acceptor solution has the same ionic concentration as the original sample (equilibrium dialysis). The acceptor solution is then injected directly into the ion chromatograph where it is analyzed. Whereas in ultrafiltration the sample solution is filtered through the membrane as a result of a difference in pressure, the driving force in dialysis is the difference in concentration between the two sides. The ions to be determined diffuse through the membrane, but no sample solution is forced through the membrane. This means that no filter cake is formed that could block the membrane. By means of this technique it is possible to determine anions and cations even in cutting oil emulsions, biodiesel, dairy products or body fluids such as blood and urine. If the system is programmed so that the next sample is dialyzed during the current run, the total analysis takes about the same time as direct injection. «Stopped flow» method An equilibrium is achieved between the acceptor solution and the sample solution Ultrafiltration 16 IC

18 Professional IC Systems «ProfIC 3 Cation» Professional IC system with Inline Dialysis Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed) with Metrohm Inline Dialysis. «ProfIC 3» safely masters demanding analytical tasks in ion chromatography. It is easy to use and extremely reliable. «ProfIC 3» features intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The Professional IC system «ProfIC 3» is equipped with «Inline Stopped Flow Dialysis», which is protected by a Metrohm patent (European Patent , US Patent 5,861,097). This fully automatic sample preparation technique effectively removes particles and colloids from the samples. Emulsions, samples containing fats and proteins, body fluids and strongly polluted wastewater can be reliably analyzed without damaging the analytical column. The driving force behind dialysis is diffusion. Only the ions and not the particles can pass through the dialysis membrane. This increases the lifetime of the membrane and, for example, prevents oil droplets from reaching the analytical column through the membrane, as would be the case if filtration was to be used. Ordering information ProfIC 3 - Cation «ProfIC 3 Cation» Professional IC system with Inline Dialysis Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x IC Equipment for dialysis IC column, sample rack, sample vials and MagIC Net have to be ordered separately according to the specific application. Numerous sample racks for volumes ml are available for the 858 Professional Sample Processor. Dialysis requires at least 10 ml of the sample. The dialysis cell is mounted directly into the 850 Professional IC. The coordinated operation of the two bidirectional peristaltic pumps at the 858 Professional Sample Processor Pump and 850 Professional IC Prep 1 enables the Inline Dialysis, which is controlled by MagIC Net. 17 IC

19 Professional IC Systems «ProfIC 4 Cation» Professional IC system with Inline Dilution Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed) in concentrated solutions. «ProfIC 4» can be used to analyze samples whose concentration is too high to be determined directly. High ionic concentrations overload the column, which results in poor chromatographic separation and therefore adversely affects the accuracy of the measurement. «ProfIC 4» allows automatic Inline Dilution of any sample. Dilution takes place at an external position of the 858 Professional Sample Processor. In combination with transfer tubing the 800 Dosino dosing system carries out the high-precision liquid handling steps. The MagIC Net software controls the dilution steps and carries out all calculations, only the dilution factor needs to be entered in the sample table. In addition, the software provides for intelligent dilution, i.e. dilution is carried out automatically depending on the predefined concentration limits. The software monitors the results and makes logical decisions. Ordering information ProfIC 4 - Cation «ProfIC 4 Cation» Professional IC system with Inline Dilution Technical information Components 1 x Dosino 1 x Magnetic stirrer 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. «ProfIC 4» features intelligent system components such as the ipump, the idetector and the 800 Dosino and provides space for a total of three icolumns. The 858 Professional Sample Processor with Pump carries out the sample transfer. Numerous sample racks for volumes ml are available. 18 IC

20 Professional IC Systems «ProfIC 5 Cation» Professional IC system with variable sample preconcentration Professional IC system applying conductivity detection. For trace analysis of cations and anions (non-supressed). With the «ProfIC 5», concentrations down to the ppb range ( g/l) can be reliably determined. The intelligent 800 Dosino carries out the high-precision sample preconcentration on the preconcentration column, which replaces the sample loop. This means that it is possible to preconcentrate and analyse more than 50 ml of the sample instead of the L sample used for direct injection via the sample loop. It is also possible to calibrate the system using the 800 Dosino dosing system. In this case it will suffice to work with the single most concentrated standard, of which varying volumes are transferred to the preconcentration column. This means that trace analyses are possible all the way down to the single-digit ppb range, even in routine analysis. «ProfIC 5» features intelligent system components such as the ipump, the idetector and the 800 Dosino dosing system and provides space for a total of three icolumns. The MagIC Net software monitors and controls the functions of all components. Ordering information ProfIC 5 - Cation «ProfIC 5 Cation» Professional IC system with variable sample preconcentration Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Metrosep I Trap 1 column 1 x PFA transfer tubing 20 ml 1 x Rinsing station for Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for liquid handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. The 858 Professional Sample Processor supplies the samples. Transfer takes place with the 800 Dosino. Numerous sample racks are available for volumes ml. The minimum volume for preconcentration is 0.5 ml. 19 IC

21 Professional IC Systems «ProfIC 6 Cation» Professional IC system with Inline Dilution and Ultrafiltration Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed) present in very high concentrations and whose matrix contains particles. «ProfIC 6» works with Metrohm Inline Dilution and Ultrafiltration. With this system it is possible to eliminate bacteria or inorganic particles from the sample and then dilute it so far that it can be analyzed. Automatic Inline Dilution of the sample is carried out at an external position of the 858 Professional Sample Processor. The 800 Dosino dosing system provides for the high-precision liquid handling steps in combination with a transfer tubing. The MagIC Net software controls the dilution steps and carries out all calculations, so that only the dilution factor needs to be entered in the sample table. In addition, the software provides for intelligent dilution, i.e. dilution takes place automatically depending on the predefined concentration limits. The software monitors all intelligent system components from the icolumn to the idetector. Ordering information ProfIC 6 - Cation «ProfIC 6 Cation» Professional IC system with Inline Dilution and Ultrafiltration Technical information Components 1 x Dosino 1 x Magnetic Stirrer 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for ultrafiltration 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The Metrohm Inline Ultrafiltration included in «ProfIC 6» reliably removes particles from the sample, which protects the analytical column and significantly increases its lifetime. The ultrafiltration cell is equipped with a membrane filter with a pore size of 0.2 m as standard and is suitable for samples with a light to medium particle load. Inline Ultrafiltration works fully automatically saving the time-consuming and expensive use of syringe filters. The 858 Professional Sample Processor with Pump carries out the sample transfer. Numerous sample racks for volumes ml are available. 20 IC

22 Professional IC Systems «ProfIC 7 Cation» Professional IC system with Inline Dilution and Dialysis Professional IC system applying conductivity detection. For the fully automatic determination of cations or anions (non-suppressed) present in high concentrations and also in critical matrices. Emulsions, samples containing fats and proteins or strongly polluted wastewater are not always compatible with ion chromatography, even after an initial filtration step. This is why «ProfIC 7» is equipped with the inline dialysis system patented by Metrohm (European Patent , US-Patent 5,861,097). In this way it is possible to determine anions and cations even in cutting oil emulsions, biodiesel, dairy products or body fluids such as blood and urine. «ProfIC 7» also enables automatic Inline Dilution of the sample. This is carried out at an external position of the 858 Professional Sample Processor. In combination with a transfer tubing, the 800 Dosino dosing system carries out the high-precision liquid handling steps. The intelligent MagIC Net software controls both the dialysis and the dilution steps. MagIC Net carries out all calculations, so that only the dilution factor needs to be entered in the sample table. The software also enables intelligent dilution, i.e. dilution takes place automatically depending on the highest concentration limits. The software monitors the results and makes logical decisions. Ordering information ProfIC 7 - Cation «ProfIC 7 Cation» Professional IC system with Inline Dilution and Dialysis Technical information Components 1 x Dosino 1 x Magnetic stirrer 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for dialysis 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The 858 Professional Sample Processor provides for sample transfer. Numerous sample racks for volumes ml are available. 21 IC

23 Professional IC Systems «ProfIC 8 Cation» Professional IC system with Inline Sample Preconcentration and Matrix Elimination The Professional IC system applying conductivity detection. For the determination of cations or anions (non-suppressed) in difficult matrices. «ProfIC 8» with Metrohm Inline Sample Preconcentration and Matrix Elimination allows chromatography unaffected by matrix influences and guarantees a long lifetime of the analytical column. A small volume of the sample is transferred fully automatically to the preconcentration column. The anions or cations are retained. The matrix can be removed in a rinsing step. The clean sample is then injected into the IC system. The 850 Professional IC Prep 2 is equipped with an additional valve for liquid handling. The peristaltic pump transfers the sample and the rinsing solutions. The intelligent MagIC Net software controls and monitors the system. Ordering information ProfIC 8 - Cation «ProfIC 8 Cation» Professional IC system with Inline Sample Preconcentration and Matrix Elimination Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Bottle neck attachment 1 x Eluent bottle 2 L, GL 45 IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The 858 Professional Sample Processor provides for sample delivery. Numerous sample racks for volumes ml are available. Only small sample volumes of about 1 ml are normally required for matrix elimination. 22 IC

24 Professional IC Systems «ProfIC 9 Cation» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination Professional IC system applying conductivity detection. For ultratrace analysis in the lowest ppt range (ng/l) of cations or anions (non-suppressed) in complex matrices. «ProfIC 9» with Metrohm Inline Sample Preconcentration and Matrix Elimination allows chromatography unaffected by matrix influences and guarantees long lifetime for the analytical column. Metrohm Inline Calibration permits very low concentrations in the lowest ppt range (ng/l) to be reliably calibrated using a single standard of higher concentration in the ppb range ( g/l). The sample is transferred to the preconcentration column fully automatically and with high precision by the intelligent 800 Dosino dosing system. The anions or cations are retained. The matrix can be removed in a rinsing step. The clean sample is then injected into the IC system. The 850 Professional IC Prep 2 is equipped with an additional valve for liquid handling. The peristaltic pump transfers the standard solution. The intelligent MagIC Net software controls and monitors the system. Calibration and calculation of the results as a function of preconcentration volume is also carried out by the MagIC Net software. Even if complex procedures are involved, operating the system is perfectly easy. Ordering information ProfIC 9 - Cation «ProfIC 9 Cation» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix elimination Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Metrosep I Trap 1 column 1 x Transfer tubing 10 ml 1 x Rinsing station for Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for liquid handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The 858 Professional Sample Processor holds the samples. Numerous sample racks for volumes ml are available. Typical preconcentration volumes are between ml. 23 IC

25 Professional IC Systems «ProfIC 15 Cation» Professional IC system for Partial Loop Injection Professional IC system applying conductivity detection. For the fully automatic determination of cations and anions (non-suppressed) and «Partial Loop Injection». «Partial Loop Injection» enables concentrated samples to be injected without previous dilution as well as multipoint calibrations using just one standard solution. «ProfIC 15» safely controls all routine tasks in ion chromatography. It is simple to use and very reliable. Excellent system components guarantee high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the MagIC Net software. «ProfIC 15» features intelligent system components such as the ipump, the idetector and the Dosino and provides space for a total of three icolumns. The 800 Dosino dosing system takes care of the sample transfer. With its high precision liquid handling, partial loop injections are performed easily and with high reproducibility. This ensures very accurate results, for example with calibration using just one standard. Ordering information ProfIC 15 - Cation «ProfIC 15 Cation» Professional IC system for Partial Loop Injection Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x PEEK sample loop 100 L 1 x PEEK capillary 0.5 mm i.d., 3 m 1 x PEEK transfer capillary 2 ml 1 x Rinsing Station for Sample Processor 1 x Dosing unit 2 ml 1 x IC Equipment for Liquid Handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately depending on the particular application. For the 858 Professional Sample Processor numerous sample racks are available for volumes in the range ml. The «ProfIC 15» is the perfect system configuration, both for routine operation and research and development. 24 IC

26 Professional IC Systems «ProfIC 1 Anion» Professional IC system for automated ion chromatography Professional IC system applying conductivity detection. For the fully automatic determination of anions with sequential suppression. «ProfIC 1» safely masters all routine tasks in ion chromatography. It is easy to use and extremely reliable. Quality components guarantee high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the MagIC Net software. «ProfIC 1» features intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. Ordering information ProfIC 1 - Anion «ProfIC 1 Anion» Professional IC system for automated ion chromatography Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately depending on the specific application. The 858 Professional Sample Processor provides for sample transfer. Numerous sample racks are available for volumes in the range ml. The «ProfIC 1» system is your reliable partner, both in routine operation and for research and development. 25 IC

27 Professional IC Systems Reproducibility of the suppression For each measurement with the Metrohm Suppressor Module «MSM II», a fresh suppressor cartridge is used. Thus, you can always be sure that you are working with a cation exchanger that delivers its full performance: today, tomorrow, and even after years of uninterrupted use. The suppressor is characterized by its pressure stability; it is 100% solvent-resistant and impresses with its long working life. As no sensitive membranes are used, the suppressor reaches its equilibrium after a very short time and is then ready for use. That is exactly the reason why we give a 10-year warranty on the «MSM II». The Metrohm Suppressor Module is favorably-priced and robust. Reproducibility of measurements made with the «MSM II» is excellent as is shown by the chromatograms: injections, separation of standard anions on the Metrosep A Supp 5-100/4.0, eluent 1.0 mmol/l NaHCO 3, 3.2 mmol/l Na 2 CO 3, flow 0.7 ml/min, loop 20 L, suppression with the Metrohm Suppressor Module «MSMII», regeneration with 50 mmol/l H 2 SO 4, rinsing with deionized water. 1 Fluoride 2 Chloride 3 Nitrite 4 Bromide 5 Nitrate 6 Phosphate 7 Sulfate Ion Fluoride Chloride Nitrite Bromide Nitrate Phosphate Sulfate Concentration (mg/l) Relative standard deviation in % (n=30) IC

28 Professional IC Systems Sequential suppression Sequential suppression is the combination of chemical suppression using the «MSM II» with Metrohm CO 2 Suppression «MCS». In this way anions can be detected with carbonate/ bicarbonate eluents at the low background conductivity of hydroxide eluents. The removal of the CO 2 prevents the carbonate equilibrium from negatively affecting the peak areas. The benefit for the user: Peak areas thus obtained are up to 50% larger at the same concentration and for the same sample volume; this means lower detection limits. No carbonate peak also means no annoying interference with the quantification of certain analyte anions. For example, chloride and carbonate coelute on many polystyrene-divinylbenzene columns. By using the CO 2 suppressor such problems are a thing of the past. The virtual elimination of the injection peak improves the determination of rapidly eluting anions, for example fluoride. Although the separation of the injection peak and fluoride peak is already very good on polyalcohol columns, the detection limits can be improved even further by using the CO 2 suppressor. As the injection peak is practically no longer visible, considerably larger sample volumes can also be injected. Drinking water from Herisau (Switzerland): comparison of suppression with «MSM II» alone (black) and with «MSM II» plus «MCS» (red). Column: Metrosep A Supp 5-100/4.0 ( ) Eluent: 3.2 mmol/l Na 2 CO 3 ; 1.0 mmol/l NaHCO 3 Flow rate: 0.7 ml/min Nr. Ion Conz. (mg/l) 1 Injection peak 2 Fluoride Chloride Carbonate 5 Bromide Nitrate Sulfate IC

29 Professional IC Systems «ProfIC 2 Anion» Professional IC system with Inline Ultrafiltration Professional IC system applying conductivity detection. For for the fully automatic determination of anions with Metrohm Inline Ultrafiltration. «ProfIC 2» safely masters all routine tasks in ion chromatography. It is easy to use and extremely reliable. Quality system components guarantee very high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the intelligent MagIC Net software. «ProfIC 2» is equipped with Metrohm Inline Ultrafiltration, which reliably removes particles from the sample and effectively protects the analytical column from contamination. The lifetime of the column is increased significantly. The ultrafiltration cell is equipped with a membrane filter with a pore size of 0.2 m as standard and is suitable for samples with a light to medium particle load. Inline Ultrafiltration works fully automatically and saves the time-consuming and expensive use of syringe filters. The ultrafiltration cell is mounted directly into the 858 Professional Sample Processor. The bidirectional dualchannel peristaltic pump provides for sample transfer through the ultrafiltration cell and to the Professional IC system. The sample is continuously delivered at a high flow rate. This delays the formation of a filter cake and increases the working life of the membrane. Cross contamination is kept below 0.1%. Ordering information ProfIC 2 - Anion «ProfIC 2 Anion» Professional IC system with Inline Ultrafiltration Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x IC Equipment for ultrafiltration IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately depending on the specific application. Numerous sample racks for volumes ml are available for the 858 Professional Sample Processor. Ultrafiltration requires at least 5 ml of the sample. «ProfIC 2» features intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The anion system is additionally equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. The «ProfIC 2» system is your reliable partner, both for routine analysis and in research and development. 28 IC

30 Professional IC Systems «ProfIC 3 Anion» Professional IC system with Inline Dialysis Professional IC system applying conductivity detection. For the fully automatic determination of anions with Metrohm inline dialysis. «ProfIC 3» safely masters demanding analytical tasks in ion chromatography. It is nevertheless simple to use and extremely reliable. «ProfIC 3» features intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The Professional IC system «ProfIC 3» is equipped with «Inline Stopped Flow Dialysis», which is protected by a Metrohm patent (European Patent , US- Patent 5,861,097). This fully automatic sample preparation technique effectively removes particles and colloids from the samples to be analyzed. Emulsions, samples containing fats and proteins, body fluids and strongly polluted wastewater can be reliably determined without damaging the analytical column. The driving force behind dialysis is diffusion. This means that only the ions and not the particles can pass through the dialysis membrane. This increases the lifetime of the membrane and, for example, prevents oil droplets from reaching the analytical column through the membrane, as would be the case if filtration was to be used. The dialysis cell is mounted directly into the 850 Professional IC. The coordinated operation of the two bidirectional peristaltic pumps at the 858 Professional Sample Processor Pump and 850 Professional IC Prep 1 enables the dialysis, which is controlled by MagIC Net. Ordering information ProfIC 3 - Anion «ProfIC 3 Anion» Professional IC system with Inline Dialysis Technical information Components 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x IC Equipment for dialysis IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The anion system is equipped with sequential suppression. Very high sensitivity is guaranteed by this unique combination of chemical and downstream CO 2 suppression. The flexibility of the carbonate eluent is complemented by the low background conductivity of a hydroxide eluent. Numerous sample racks for volumes ml are available for the 858 Professional Sample Processor. Dialysis requires at least 10 ml of the sample. 29 IC

31 Professional IC Systems «ProfIC 4 Anion» Professional IC system with Inline Dilution Professional IC system applying conductivity detection. For the fully automatic determination of anions in concentrated solutions. «ProfIC 4» can be used to analyze samples with concentration too high to be determined directly. High Ionic concentrations overload the column, which results in a poor chromatographic separation and therefore adversely affects the accuracy of the measurement. «ProfIC 4» allows the automatic Inline Dilution of any sample. Dilution takes place at an external position of the 858 Professional Sample Processor. In combination with transfer tubing the 800 Dosino carries out the high-precision liquid handling steps. The MagIC Net software controls the dilution steps and carries out all calculations, so that only the dilution factor needs to be entered in the sample table. Moreover, the software provides for intelligent dilution, i.e. dilution takes place automatically depending on the highest concentration limits. The software monitors the results and makes logical decisions. «ProfIC 4» features intelligent system components such as the ipump, the idetector and the 800 Dosino and provides space for a total of three icolumns. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate Ordering information ProfIC 4 - Anion «ProfIC 4 Anion» Professional IC system with Inline Dilution Technical information Components 1 x Dosino 1 x Magnetic stirrer 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. eluent is complemented by the low background conductivity of a hydroxide eluent. The 858 Professional Sample Processor with Pump provides for the sample transfer. Numerous sample racks for volumes ml are available. 30 IC

32 Professional IC Systems «ProfIC 5 Anion» Professional IC system with variable sample preconcentration Professional IC system applying conductivity detection. For trace analysis of anions. With the «ProfIC 5», concentrations down to the ppb range ( g/l) can be reliably determined. The intelligent 800 Dosino dosing system carries out the high-precision sample preconcentration on the preconcentration column, which replaces the sample loop. This means that it is possible to preconcentrate and analyse more than 50 ml of the sample instead of the L sample used for direct injection via the sample loop. The system can be calibrated using the 800 Dosino. In this case it will suffice to work with the single most concentrated standard, of which varying volumes are transferred to the preconcentration column. This allows trace analyis right down to the the single digit ppb range even in routine analysis. «ProfIC 5» features intelligent system components such as the ipump, the idetector and the 800 Dosino dosing system and provides space for a total of three icolumns. The MagIC Net software monitors and controls the functions of all components. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression enables very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. With the preconcentration technique carbonate interference is practically eliminated. Ordering information ProfIC 5 - Anion «ProfIC 5 Anion» Professional IC system with variable sample preconcentration Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Metrosep I Trap 1 column 1 x PEEK transfer tubing 10 ml 1 x Rinsing station for Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for liquid handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. The 858 Professional Sample Processor supplies the samples. Transfer is carried out by the 800 Dosino dosing system. Numerous sample racks are available for volumes ml. The minimum volume for preconcentration is 0.5 ml. 31 IC

33 Professional IC Systems «ProfIC 6 Anion» Professional IC system with Inline Dilution and Ultrafiltration Professional IC system applying conductivity detection. For the fully automatic determination of anions in very high concentrations in matrices containing particles. «ProfIC 6» works with Metrohm Inline Dilution and Ultrafiltration. This system enables users to dilute the sample and eliminate bacteria or inorganic particles prior to analysis. Automatic Inline Dilution of the sample is carried out at an external position of the 858 Professional Sample Processor. The 800 Dosino dosing system carries out the high-precision liquid handling steps. The MagIC Net software controls the dilution steps and provides for all calculations; only the dilution factor needs to be entered in the sample table. In addition, the software provides for intelligent dilution, i.e. dilution takes place automatically depending on the predefined concentration limits. The software monitors all intelligent system components from the icolumn to the idetector. The Metrohm Inline Ultrafiltration included in «ProfIC 6» reliably removes particles from the sample protecting the analytical column and increasing its lifetime significantly. The ultrafiltration cell is equipped with a membrane filter with a pore size of 0.2 m as standard and is suitable for samples with a light to medium particle load. Inline Ultrafiltration works fully automatically saving the time-consuming and expensive use of syringe filters. Ordering information ProfIC 6 - Anion «ProfIC 6 Anion» Professional IC system with Inline Dilution and Ultrafiltration Technical information Components 1 x Dosino 1 x Magnetic Stirrer 1 x Professional IC Anion 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for ultrafiltration 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The anion system is equipped with sequential suppression. Very high sensitivity is achieved by this unique combination of chemical and downstream CO 2 suppression. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. The 858 Professional Sample Processor with Pump carries out the sample transfer. Numerous sample racks for volumes ml are available. 32 IC

34 Professional IC Systems «ProfIC 7 Anion» Professional IC system with Inline Dilution and Dialysis Professional IC system applying conductivity detection. For the fully automatic determination of anions in high concentrations and in critical matrices. Emulsions, samples containing fats and proteins or strongly polluted wastewater are not always compatible with ion chromatography, even after filtration. This is why «ProfIC 7» is equipped with the Inline Dialysis system patented by Metrohm (European Patent , US-Patent 5,861,097). In this way it is possible to determine anions and cations even in cutting oil emulsions, dairy products or body fluids such as blood and urine. «ProfIC 7» also enables automatic Inline Dilution of the sample. This takes place at an external position of the 858 Professional Sample Processor. The 800 Dosino carries out the high-precision liquid handling steps. The intelligent MagIC Net software controls both the dialysis and the dilution steps. MagIC Net provides for all calculations; only the dilution factor needs to be entered in the sample table. In addition, the software provides for intelligent dilution, i.e. dilution takes place automatically depending on the predefined concentration limits. The software monitors the results and makes logical decisions. Ordering information ProfIC 7 - Anion «ProfIC 7 Anion» Professional IC system with Inline Dilution and Dialysis Technical information Components 1 x Dosino 1 x Magnetic Stirrer 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for dialysis 1 x IC Equipment for sample dilution IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The anion system is equipped with sequential suppression. Very high sensitivity is achieved by this unique combination of chemical and downstream CO 2 suppression. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. The 858 Professional Sample Processor with Pump carries out the sample transfer. Numerous sample racks for volumes ml are available. 33 IC

35 Professional IC Systems «ProfIC 8 Anion» Professional IC system with Inline Sample Preconcentration and Matrix Elimination Professional IC system applying conductivity detection. For the determination of anions in difficult matrices. «ProfIC 8» with Metrohm Inline Sample Preconcentration and Matrix elimination allows chromatography unaffected by matrix influences and guarantees a long lifetime of the analytical column. A small volume of the sample is transferred fully automatically to the preconcentration column. The anions are retained. The matrix can be removed in a rinsing step. The clean sample is then injected into the IC system. The 850 Professional IC Prep 2 is equipped with an additional valve for liquid handling. The peristaltic pump transfers the sample and the rinsing solutions. The intelligent MagIC Net software controls and monitors the system. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. With the preconcentration technique carbonate interference is practically eliminated. Ordering information ProfIC 8 - Anion «ProfIC 8 Anion» Professional IC system with Inline Sample Preconcentration and Matrix elimination Technical information Components 1 x Professional IC Anion 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Bottle neck attachment 1 x Eluent bottle 2 L, GL 45 IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The 858 Professional Sample Processor provides for sample delivery. Numerous sample racks for volumes ml are available. Only small sample volumes of about 1 ml are normally required for Matrix Elimination. 34 IC

36 Professional IC Systems «ProfIC 9 Anion» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination Professional IC system applying conductivity detection. For ultratrace analysis in the lowest ppt range (ng/l) of anions in complex matrices. «ProfIC 9» with Metrohm Inline Sample Preconcentration and Matrix Elimination allows chromatography unaffected by matrix influences and guarantees that the analytical column has a long working life. Metrohm Inline Calibration permits very low concentrations in the lowest ppt range to be reliably calibrated using a single standard of higher concentration in the ppb range. The sample is transferred to the preconcentration column fully automatically and with high precision by the intelligent 800 Dosino dosing system. The anions are retained. The matrix can be removed in a rinsing step. The clean sample is then injected into the IC system. The 850 Professional IC Prep 2 is equipped with an additional valve for liquid handling. The peristaltic pump transfers the standard solution. The intelligent MagIC Net software controls and monitors the system. Calibration and calculation of the results as a function of preconcentration volume are also provided by the MagIC Net software. Even if complex procedures are involved, operating the system is perfectly simple. Ordering information ProfIC 9 - Anion «ProfIC 9 Anion» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Metrosep I Trap 1 Column 1 x PEEK Transfer tubing 10 ml 1 x Rinsing station for Sample Processor 1 x Dosing unit 10 ml 1 x IC Equipment for liquid handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. The anion system is equipped with sequential suppression. Very high sensitivity is achieved by this unique combination of chemical and downstream CO 2 suppression. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. With the preconcentration technique carbonate interference is practically eliminated. The 858 Professional Sample Processor holds the samples. Numerous sample racks for volumes ml are available. Typical preconcentration volumes are between ml. 35 IC

37 Professional IC Systems «ProfIC 10 Anion» Professional IC system with Inline Sample Preconcentration, Matrix Elimination and Matrix Neutralisation Professional IC system applying conductivity detection. For the determination of anions in difficult matrices. «ProfIC 10» with Metrohm Inline Sample Preconcentration, Matrix Neutralisation and Matrix Elimination allows chromatography unaffected by matrix influences and guarantees that the analytical column has a long lifetime. A small volume of the sample is transferred fully automatically to the preconcentration column. On its way it passes through the sample preparation module, where an almost complete cation exchange takes place. This means that it is possible to neutralise both acids and alkalis. The matrix is then removed from the preconcentration column in a rinsing step and the clean and ph-neutral sample injected into the IC system. For liquid handling, the 858 Professional Sample Processor Pump Injector is equipped with an additional valve. An additional peristaltic pump transfers the sample and rinsing solutions. The intelligent MagIC Net software controls and monitors the system. «ProfIC 10» is equipped with sequential suppression. Very high sensitivity is achieved by this unique combination of chemical and downstream CO 2 suppression. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. With the preconcentration technique, carbonate interference is practically eliminated. Ordering information ProfIC 10 - Anion «ProfIC 10 Anion» Professional IC system with Inline Sample Preconcentration, Matrix Elimination and Matrix Neutralisation Technical information Components 1 x Professional IC Anion 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Bottle neck attachment 1 x Eluent bottle 2 L, GL 45 1 x PEEK sample loop 10 L IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. «ProfIC 10» features intelligent system components such as the ipump and the idetector and provides space for a total of three icolumns. The 858 Professional Sample Processor Pump Injector provides for sample delivery. Numerous sample racks for volumes ml are available. Only small sample volumes of about 1 ml are normally required for Matrix Elimination and Neutralisation. 36 IC

38 Professional IC Systems «ProfIC 11 Anion» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination Professional IC system applying conductivity detection. For ultratrace analysis of anions in complex matrices. «ProfIC 11» with Metrohm Inline Neutralisation, Sample Preconcentration and Matrix Elimination allows chromatography unaffected by matrix influences and guarantees al long lifetime of the analytical column. Metrohm Inline Calibration permits very low concentrations in the ppt range (ng/l) to be reliably calibrated using a single standard of higher concentration in the ppb range ( g/l). The sample is transferred to the preconcentration column fully automatically and with high precision by the intelligent 800 Dosino dosing system. On its way it passes through the sample preparation module, where complete cation exchange takes place. This means that it is possible to neutralise both acids and bases. The matrix is then removed from the preconcentration column in a rinsing step. The ph-neutral and matrixfree sample is then injected into the IC system. The preconcentration becomes possible as a result of the neutralisation of the sample. The 850 Professional IC Prep 3 is equipped with a sample preparation module. Sample and rinsing solution are provided by the 800 Dosino. A valve on the 858 Professional Sample Processor switches between sampling and sample transfer. The 872 Extension Module is used for Inline Calibration. The intelligent MagIC Net software controls and monitors the system. Ordering information ProfIC 11 - Anion «ProfIC 11 Anion» Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination Technical information Components 1 x Dosino 1 x Professional IC 1 x Conductivity Detector 1 x Professional Sample Processor 1 x Extension Module Sample Prep 1 x Metrosep I Trap 1 Column 1 x PEEK Transfer tubing 10 ml 1 x Rinsing station for Sample Processor 1 x Dosing unit 5 ml 1 x IC Equipment for liquid handling IC column, preconcentration column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the specific application. Calibration and calculation of the results as a function of preconcentration volume are also provided by the MagIC Net software. Different sample volumes can be conveniently entered in the sample table. Even if complex procedures are involved, operating the system is perfectly easy. «ProfIC 11» features intelligent system components such as the ipump, the idetector and the Dosino and provides space for a total of three icolumns. The system is equipped with sequential suppression. The 858 Professional Sample Processor Pump Injector provides for sample delivery. Numerous sample racks for volumes ml are available. 37 IC

39 Professional IC Systems «ProfIC 12 Anion» Professional IC gradient system Professional IC system applying conductivity detection. For the determination of anions with a binary highpressure gradient. In addition to step gradients, this system can be used to run any linear, convex or concave gradients to work in a time-optimized way. «ProfIC 12» is equipped with two high-pressure pumps and a very effective passive mixing device. The 872 Extension Module IC Pump can be used to upgrade the system to a quaternary gradient. «ProfIC 12» works with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. The removal of carbon dioxide additionally reduces baseline drift during the gradient run. Ordering information ProfIC 12 - Anion «ProfIC 12 Anion» Professional IC gradient system Technical information Components 1 x Professional IC Anion 1 x Conductivity Detector 1 x Professional Sample Processor IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. The MagIC Net software is used for controlling the system and programming the gradient. All system functions, from monitoring the service interval to calibration, can be monitored by MagIC Net. «ProfIC 12» features intelligent system components such as two ipumps and the idetector and provides space for a total of three icolumns. The 858 Professional Sample Processor Pump provides for for sample delivery. Numerous sample racks for volumes ml are available. 38 IC

40 Professional IC Systems «ProfIC 15 Anion» Professional IC system for Partial Loop Injection Professional IC system applying conductivity detection. For the fully automatic determination of anions with sequential suppression and Partial Loop Injection capability. «Partial Loop Injection» enables concentrated samples to be injected without previous dilution as well as multipoint calibrations using just one standard solution. «ProfIC 15» safely controls all routine tasks in ion chromatography. It is easy to use and very reliable. Excellent system components guarantee high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the MagIC Net software. «ProfIC 15» features intelligent system components such as the ipump, the idetector and the 800 Dosino and provides space for a total of three icolumns. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent can thus be combined with the low background conductivity of a hydroxide eluent. The 800 Dosino dosing system provides for the sample transfer. Due to its high precision liquid handling, Partial Loop Injections are performed easily and with high reproducibility. This ensures very accurate results, for example with calibration using one single solution. Ordering information ProfIC 15 - Anion «ProfIC 15 Anion» Professional IC system for Partial Loop Injection Technical information Components 1 x Dosino 1 x Professional IC Anion 1 x Conductivity Detector 1 x Professional Sample Processor 1 x PEEK sample loop 100 L 1 x PEEK-capillary 0.5 mm i.d., 3 m 1 x PEEK transfer capillary 2 ml 1 x Rinsing Station for Sample Processor 1 x Dosing unit 2 ml 1 x IC Equipment for Liquid Handling IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. For the 858 Professional Sample Processor numerous sample racks are available for volumes in the range ml. The «ProfIC 15» system is your reliable partner, both for routine operation and in research and development. 39 IC

41 Professional IC Systems «ProfIC 1 AnCat» Professional IC system for automated ion chromatography Very compact Professional IC system applying conductivity detection for the fully automatic determination of anions and cations. With «ProfIC 1 AnCat» anions and cations can be determined both in parallel as well as independently. Both systems use the same 858 Professional Sample Processor with pump, which is controlled by the MagIC Net software. The «ProfIC 1 AnCat» safely performs all routine tasks in ion chromatography. It is simple to operate and very reliable. Excellent system components guarantee low detection limits and reproducible results. Particular attention has been given to long service intervals; these can be monitored with the MagIC Net software. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. «ProfIC 1 AnCat» features two ipumps as well as two idetectors and provides space for a total of three icolumns in two different temperature ranges. Ordering information ProfIC 1 - AnCat «ProfIC 1 AnCat» Professional IC system for automated ion chromatography Technical information Components 1 x Professional IC 2 x Conductivity Detector 1 x Professional Sample Processor IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. The «ProfIC 1-AnCat» system is your reliable partner, both for routine operation and in research and development. The 858 Professional Sample Processor Pump provides for the sample transfer. Numerous sample racks for volumes ml are available. 40 IC

42 Professional IC Systems «ProfIC 2 AnCat» Professional IC system with Inline Ultrafiltration The very compact Professional IC system applying conductivity detection for the fully automatic determination of anions and cations with Metrohm Inline Ultrafiltration. With «ProfIC 2 AnCat» anions and cations can be determined both in parallel as well as independently in order to save time. Both systems use the same 858 Professional Sample Processor with pump, which is controlled by the MagIC Net software. The «ProfIC 2 AnCat» performs all routine tasks in ion chromatography. It is simple to operate and very reliable. Excellent system components guarantee low detection limits and reproducible results. Particular attention has been given to long service intervals; these can be monitored with the MagIC Net software. «ProfIC 2 AnCat» is equipped with Metrohm Inline Ultrafiltration, which reliably removes particles from the sample protecting the analytical column particulate contamination. The lifetime of the column is significantly increased. The ultrafiltration cell is equipped with a membrane filter with a pore size of 0.2 m as standard and is suitable for samples with a light to medium particle load. Inline Ultrafiltration works fully automatically saving the time-consuming and expensive use of syringe filters. The ultrafiltration cell is mounted directly into the 858 Professional Sample Processor. The bidirectional dualchannel peristaltic pump carries out the sample transfer through the ultrafiltration cell and to the Professional IC system. Ordering information ProfIC 2 - AnCat «ProfIC 2 AnCat» Professional IC system with Inline Ultrafiltration Technical information Components 1 x Professional IC 2 x Conductivity Detector 1 x Professional Sample Processor 1 x IC Equipment for ultrafiltration IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. The anion system is additionally equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. «ProfIC 2 AnCat» features two ipumps as well as two idetectors and provides space for a total of three icolumns in two different temperature ranges. Numerous sample racks for volumes ml are available. Ultrafiltration requires a sample volume of at least 5 ml. The «ProfIC 2-AnCat» system is your reliable partner, both for routine operation and in research and development. 41 IC

43 Professional IC Systems «ProfIC 15 AnCat» Professional IC system for Partial Loop Injection Very compact Professional IC system applying conductivity detection for the fully automatic determination of anions with sequential suppression and cations with Partial Loop Injection capability. «Partial Loop Injection» allows concentrated samples to be injected without previous dilution as well as multipoint calibrations using just one standard solution. «ProfIC 15» safely controls all routine tasks in ion chromatography. It is simple to use and very flexible. Excellent system components guarantee high sensitivity and reproducible results. Particular attention has been given to long service intervals; these can be monitored by the MagIC Net software. «ProfIC 15 AnCat» features two ipumps, two Dosinos as well as two idetectors and provides space for a total of three icolumns in two different temperature ranges. The anion system is equipped with sequential suppression. This unique combination of chemical and downstream CO 2 suppression results in very low detection limits. The flexibility of the carbonate/hydrocarbonate eluent is complemented by the low background conductivity of a hydroxide eluent. The 800 Dosino dosing system provides for the sample transfer. Due to its high precision liquid handling, Partial Loop Injections are performed easily and with high reproducibility. This ensures very accurate results, Ordering information ProfIC 15 - AnCat «ProfIC 15 AnCat» Professional IC system for partial loop injection Technical information Components 2 x Dosino 1 x Professional IC 2 x Conductivity Detector 1 x Professional Sample Processor 1 x PEEK sample loop 100 L 1 x PEEK-capillary 0.5 mm i.d., 3 m 1 x PEEK transfer capillary 2 ml 1 x T-connector with holder 1 x Rinsing Station for Sample Processor 1 x Dosing unit 2 ml 1 x IC Equipment for Liquid Handling IC column, sample rack, sample vials as well as MagIC Net have to be ordered separately according to the particular application. for example when calibrating using one single standard solution. For the 858 Professional Sample Processor numerous sample racks are available for volumes in the range ml. The «ProfIC 15» is the perfect system configuration, both for routine operation and research and development. 42 IC

44 Professional IC Instruments Professional IC Instruments Professional IC Instrument Introduction 850 Professional IC intelligent ion chromatography Configuration: configuration of the system could not be easier, as the components log themselves in automatically and all the relevant information is available to the MagIC Net software. Monitoring: the system monitors and optimises all functions and, if required, documents them in an FDAcompatible form. Optimal operation of the 850 Professional IC and results are monitored. If a parameter is outside the predefined range, then the user is informed by or SMS. Free choice of detection mode: The detection mode can be choosen. Therefore no detector is included in the scope of delivery. - Intelligent pump: ipump - Intelligent detector: idetector - Intelligent column: icolumn - Intelligent liquid handling with Dosinos - Extension Module Inline sample preparation: the way from sample preparation to precise result has become shorter, as now even complex sample preparation steps can be carried out inline and automatically. The system automatically optimises sample preconcentration or dilution as required. 43 IC

45 Professional IC Instruments 850 Professional IC detectors 850 Professional IC Detector idetector ( ) Compact and intelligent high performance conductivity detector for intelligent IC Instruments. Outstanding temperature stability, the complete signal processing within the protected detector block and the latest generation of «DSP» Digital Signal Processing guarantee the highest precision of the measurement. No change of measuring ranges not even automatic is required due to the dynamic working range. 887 Professional UV/VIS Detector ( ) The 887 Professional UV/VIS Detector is an alternative to the conductivity detector and expands the family of intelligent Metrohm detectors. It allows the reliable quantification of components that absorb ultraviolet or visible light. Detection is by a diode array. 44 IC

46 Professional IC Instruments Overwiew on 850 Professional IC instruments Comparison of the different 850 Professional IC instruments IC Module ipump + Valve Suppression Sample preparation Gradient MSM MSM-HC MCS Prep 1 Prep 2 Prep 3 HPG LPG PP + MSM PP + MSM-HC Professional IC Cation yes Professional IC Cation Prep 1 yes yes Professional IC Cation Prep 2 yes yes Professional IC Cation LP Gradient yes yes Professional IC Cation Gradient yes yes Professional IC Anion yes yes Professional IC Anion MCS yes yes yes Professional IC Anion MSM-HC yes yes Professional IC Anion MSM-HC MCS yes yes yes Professional IC Anion MCS Prep 1 yes yes yes yes Professional IC Anion MSM-HC MCS Prep 1 yes yes yes yes Professional IC Anion MSM-HC MCS Prep 2 yes yes yes yes Professional IC Anion MCS Prep 2 yes yes yes yes Professional IC Anion MSM-HC MCS Prep 3 yes yes yes yes yes Professional IC Anion MCS Prep 3 yes yes yes yes Professional IC Anion MCS LP Gradient yes yes yes Professional IC Anion MCS Gradient yes yes yes Professional IC Anion MSM-HC MCS LP Gradient yes yes yes yes Professional IC Anion MSM-HC MCS Gradient yes yes yes yes Professional IC Anion MSM-HC LP Gradient yes yes yes Professional IC Anion MSM-HC Gradient yes yes yes Professional IC AnCat non-suppressed yes, 2x Professional IC AnCat yes, 2x yes Professional IC AnCat MCS Professional IC AnCat MSM-HC MCS MCS PP PP + Valve PP + SPM ipump yes, 2x yes yes LP- Device yes, 2x yes yes 45 IC

47 Professional IC Instruments 850 Professional IC instruments for cation determination 850 Professional IC Cation ( ) The 850 Professional IC Cation is an intelligent ion chromatography system for the determination of anions or cations without suppression. It may be combined with different detector types. 850 Professional IC Cation Prep 1 ( ) The 850 Professional IC Cation Prep 1 is an intelligent ion chromatography system for the determination of anions or cations without suppression in combination with sample preparation techniques such as Ultrafiltration and Dialysis. It may be combined with different detector types. 850 Professional IC Cation Prep 2 ( ) The 850 Professional IC Cation Prep 2 is an intelligent ion chromatography system for the determination of anions or cations without suppression after sample preparation. The system is suitable for the integration of Metrohm Iinline Sample Preconcentration, matrix elimination or inline calibration. It may be combined with different detector types. 46 IC

48 Professional IC Instruments 850 Professional IC instruments for anion determination 850 Professional IC Anion ( ) The 850 Professional IC Anion is an intelligent ion chromatography system for the determination of anions with chemical suppression. It may be combined with different detector types. 850 Professional IC Anion MSM-HC ( ) The 850 Professional IC Anion MSM-HC is an intelligent ion chromatography system for the determination of anions with high-capacity chemical suppression. It may be combined with different detector types. 850 Professional IC Anion MCS ( ) The 850 Professional IC Anion MCS is an intelligent ion chromatography system for the determination of anions with sequential suppression. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS ( ) The 850 Professional IC Anion MSM-HC MCS is an intelligent ion chromatography system for the determination of anions with high-capacity sequential suppression. It may be combined with different detector types. 47 IC

49 Professional IC Instruments 850 Professional IC Anion MCS Prep 1 ( ) The 850 Professional IC Anion MCS Prep 1 is an intelligent ion chromatography system for the determination of anions with sequential suppression in combination with Metrohm Inline Sample Preparation Techniques such as Ultrafiltration or Dialysis. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS Prep 1 ( ) The 850 Professional IC Anion MSM-HC MCS Prep 1 is an intelligent ion chromatography system for the determination of anions with high-capacity sequential suppression in combination with Metrohm Inline Sample Preparation Techniques such as Ultrafiltration or Dialysis. It may be combined with different detector types. 850 Professional IC Anion MCS Prep 2 ( ) The 850 Professional IC Anion MCS Prep 2 is an intelligent ion chromatography system for the determination of anions with sequential suppression. At the same time it allows fully automatic sample preparation with Metrohm Inline Sample Preconcentration, Inline Matrix Elimination or Inline Calibration. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS Prep 2 ( ) The 850 Professional IC Anion MSM-HC MCS Prep 2 is an intelligent ion chromatography system for the determination of anions with high-capacity sequential suppression. At the same time it allows fully automatic sample preparation with Metrohm Inline Sample Preconcentration, Inline Matrix Elimination or Inline Calibration. It may be combined with different detector types. 48 IC

50 Professional IC Instruments 850 Professional IC Anion MCS Prep 3 ( ) The 850 Professional IC Anion MCS Prep 3 is an intelligent ion chromatography system for the determination of anions with sequential suppression with simultaneous Metrohm Inline Neutralization or Metrohm Inline Cation Removal. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS Prep 3 ( ) The 850 Professional IC Anion MSM-HC MCS Prep 3 is an intelligent ion chromatography system for the determination of anions with high-capacity sequential suppression with simultaneous Metrohm Inline Neutralization or Metrohm Inline Cation Removal. It may be combined with different detector types. 850 Professional IC instruments with gradient 850 Professional IC Cation LP Gradient ( ) The 850 Professional IC Cation LP Gradient is an intelligent ion chromatography system with low pressure gradient but without suppression. This instrument may be combined with any separation and detection mode requiring no suppression. It may be combined with different detector types. 850 Professional IC Anion MSM-HC LP Gradient ( ) The 850 Professional IC Anion MSM-HC LP Gradient is an intelligent ion chromatography system for the determination of anions using high-capacity chemical suppression and low-pressure gradient. It may be combined with different detector types. 49 IC

51 Professional IC Instruments 850 Professional IC Anion MCS LP Gradient ( ) The 850 Professional IC Anion MCS LP Gradient is an intelligent ion chromatography system for the determination of anions using sequential suppression and low-pressure gradient. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS LP Gradient ( ) The 850 Professional IC Anion MSM-HC MCS LP Gradient is an intelligent ion chromatography system for the determination of anions using high-capacity sequential suppression and low-pressure gradient. It may be combined with different detector types. 850 Professional IC Cation Gradient ( ) The 850 Professional IC Cation Gradient is an intelligent ion chromatography system for high pressure gradients without suppression. This instrument may be combined with any separation and detection method requiring no suppression. It may be combined with different detector types. 850 Professional IC Anion MSM-HC Gradient ( ) The 850 Professional IC Anion MSM-HC Gradient is an intelligent ion chromatography system for the determination of anions with high-capacity chemical suppression and binary high-pressure gradient. It may be combined with different detector types. 50 IC

52 Professional IC Instruments 850 Professional IC Anion MCS Gradient ( ) The 850 Professional IC Anion MCS Gradient is an intelligent ion chromatography system for the determination of anions with sequential suppression and binary high-pressure gradient. It may be combined with different detector types. 850 Professional IC Anion MSM-HC MCS Gradient ( ) The 850 Professional IC Anion MSM-HC MCS Gradient is an intelligent ion chromatography system for the determination of anions with high-capacity sequential suppression and binary high-pressure gradient. It may be combined with different detector types. 850 Professional IC instruments for anion and cation determination 850 Professional IC AnCat non-suppressed ( ) The 850 Professional IC AnCat non-suppressed is an intelligent ion chromatography system for the determination of anions and cations without suppression. It may be combined with different detector types. 850 Professional IC AnCat ( ) The 850 Professional IC AnCat is an intelligent ion chromatography system for the determination of cations without suppression and anions either with or without chemical suppression, as required. It may be combined with different detector types. 51 IC

53 Professional IC Instruments 850 Professional IC AnCat MCS ( ) The 850 Professional IC AnCat MCS is an intelligent ion chromatography system for the determination of cations without suppression and anions either with or without sequential suppression, as required. It may be combined with different detector types. 850 Professional IC AnCat MSM-HC MCS ( ) The 850 Professional IC AnCat MSM-HC MCS is an intelligent ion chromatography system for the determination of cations without suppression and anions either with or without high-capacity sequential suppression, as required. It may be combined with different detector types. 52 IC

54 Professional IC Instruments Overwiew on 872 Extension Modules Extension Module IC Pump Extension Module IC Module Extension Module Sample Prep Extension Module Liquid Handling Extension Module Suppression Extension Module Suppression MCS IC Module ipump + Valve Suppression Sample Preparation Gradient Liquid Handling MSM MSM-HC MCS Prep 1 Prep 2 Prep 3 HPG LPG PP + MSM PP + MSM-HC MCS PP PP + Valve PP + SPM ipump LP- Device PP + Valve + Selection Valve yes yes yes yes yes yes yes 53 IC

55 Professional IC Instruments 872 Professional IC Extension Modules 872 Extension Module IC Pump ( ) The 872 Extension Module IC Pump is an extension tool for upgrading any 850 Professional IC instrument. It allows an additional IC high-pressure pump «ipump» to be installed in any 850 Professional IC system. 872 Extension Module IC Module ( ) The 872 Extension Module IC Module is an extension tool for upgrading any 850 Professional IC instrument. It allows an IC high-pressure pump «ipump» and an injection valve to be installed in any 850 Professional IC system. 872 Extension Module Sample Prep ( ) The 872 Extension Module Sample Prep is an extension tool for upgrading any 850 Professional IC instrument. It enables an additional peristaltic pump and injection valve to be installed in any 850 Professional IC system. 872 Extension Module Liquid Handling ( ) The 872 Extension Module Liquid Handling is an extension tool for upgrading any 850 Professional IC instrument. It enables an additional peristaltic pump, an additional injection valve as well as a 10-port selector valve to be installed in any 850 Professional IC system. 54 IC

56 Professional IC Instruments 872 Extension Module Suppression ( ) The 872 Extension Module Suppression is an extension tool for upgrading any 850 Professional IC instrument. It allows to install a complete chemical suppression in any 850 Professional IC system. 872 Extension Module Suppression MCS ( ) The 872 Extension Module Suppression MCS is an extension tool for upgrading any 850 Professional IC instrument. It allows a complete sequential suppression to be installed in any 850 Professional IC system. 55 IC

57 Compact IC Instruments 56 IC

58 Compact IC Instruments Compact IC Instruments Compact IC Instruments Introduction Compact intelligence for ion chromatography 881 Compact IC pro 882 Compact IC plus and 883 Basic IC plus Intelligent. Safe. Precise. Metrohm's high-end ion chromatograph is the 850 Professional IC, whose intelligent system components define the standards regarding precision of results and ease of operation. This technology is now available for the Compact IC instruments as well. The 881 Compact IC pro and the 882 Compact IC plus are the ideal choice for users from all fields of application with clearly defined analytical requirements. These instruments ensure the rapid and safe determination of anions, cations and polar substances in the g/l to the g/l range. do not include these modules. The detection mode can be choosen. Therefore no detector is included in the scope of delivery of the Compact IC instruments. The 883 Basic IC plus is the ideal instrument for training in higher education. It may be used with the included 850 Professional Conductivity Detector and the MagIC Net Basic software. All intelligent functions of the Professional IC instrument series have been integrated into the 881, 882 and 883 Compact instruments: ipump, idetector, icolumn technology. They guarantee precise results and help prevent operator errors. The MagIC Net chromatography software controls all system components and monitors all parameters that are relevant to the chromatographic analysis. The 881 Compact IC pro instruments are equipped with column heater and eluent degasser; the version with sequential suppression comes with an additional sample degasser. The 882 Compact IC plus instruments 57 IC

59 Compact IC Instruments Overwiew on Compact IC Instruments Comparison on the 872 Extension Moduls MSM MCS Columnheater Eluent degasser Sample degasser Automation capability 815 included Software included yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes 58 IC

60 Compact IC Instruments Compact IC pro instruments 881 Compact IC pro Cation ( ) The 881 Compact IC pro Cation is an intelligent ion chromatograph in compact design with column heating for the determination of anions, cations or polar substances without suppression. It may be combined with different detector types. 881 Compact IC pro Anion ( ) The 881 Compact IC pro Anion is an intelligent ion chromatograph in compact design with column heating for the determination of anions or polar substances with chemical suppression. It may be combined with different detector types. 881 Compact IC pro Anion MCS ( ) The 881 Compact IC pro Anion MCS is an intelligent ion chromatograph in compact design with column heating for the determination of anions or polar substances with sequential suppression. It may be combined with different detector types. 59 IC

61 Compact IC Instruments Compact IC plus instruments 882 Compact IC plus Cation ( ) The 882 Compact IC plus Cation is an intelligent ion chromatograph in compact design without column heating for the determination of anions, cations or polar substances without chemical suppression. It may be combined with different detector types. 882 Compact IC plus Anion ( ) The 882 Compact IC plus Anion is an intelligent ion chromatograph in compact design without column heating for the determination of anions or polar substances with chemical suppression. It may be combined with different detector types. 882 Compact IC plus Anion MCS ( ) The 882 Compact IC plus Anion MCS is an intelligent ion chromatograph in compact design without column heating for the determination of anions or polar substances with sequential suppression. It may be combined with different detector types. 60 IC

62 Compact IC Instruments Basic IC plus instruments 883 Basic IC plus ( ) The 883 Basic IC plus is an intelligent, very compact ion chromatograph for training and routine applications. For determination of cations and anions with and without chemical suppression. Inclusive MagIC Net Basic software and text book. 883 Basic IC plus Package ( ) Package for the automated analysis with the 883 Basic IC plus. For training and routine analysis. For determination of cations and anions with or without chemical suppression. Including 883 Basic IC plus, 863 Compact IC Autosampler, MagIC Net Basic software and textbook. 61 IC

63 Additional IC Componets 62 IC

64 Additional IC Componets Alternative IC Components Alternative IC Components Introduction Ion Chromatography is established in the laboratoies as a powerful and flexible analysis tool. Alternative IC components enhance the spectrum of analytes that can be detected. They also improve sensitivity and selectivity. Heatable modules are applied in post-column reaction systems as well as in Metrohm Inline Sample Preparation (MISP). Data converters export or import the chromatographic data to external integration systems and from external detectors respectively. Electrochemical detectors are used in stand-alone systems or in combination with conductivity detection. 63 IC

65 Additional IC Componets Heatable Reactors and Column Compartments 886 Professional Reactor ( ) The 886 Professional Reactor is a heated module specially designed for pre-column and post-column reaction applications. It excels by its ruggedness, the high heating speed and the possibility to run reactions up to 120 C. 886 Professional Thermostat ( ) The 886 Professional Thermostat is a stand-alone Column oven for up to two columns with a maximum length of 150 mm. It excels by its ruggedness, the high heating speed and the possibility to run reactions up to 80 C. IC interfaces 891 Professional Analog Out ( ) The 891 Professional Analog Out is an additional module for intelligent IC instruments. It allows to transfer analog signals of different chromatographic data to external data systems. 64 IC

66 Additional IC Componets 771 IC Compact Interface ( ) Universal analog-digital converter with two channels and 24-bit resolution. Data is transferred to the PC via an RS 232C interface for processing by IC Net or MagIC Net software. 771 IC Compact Interface; MagIC Net Professional ( ) IC Compact Interface with MagIC Net Professional software. The 771 Compact Interface connects the analog signals of the existing IC instruments (Compact, Modular and Advanced) with the improved capabilities of the client/server and database-based technology of the MagIC Net software. 771 IC Compact Interface; MagIC Net Compact ( ) IC Compact Interface with MagIC Net Compact Software. The 771 Compact Interface connects the analogue signals of the existing IC instruments (Compact, Modular and Advanced) to the improved capabilities of the client/server and database-based technology of the MagIC Net software. 65 IC

67 Additional IC Componets Electrochemical detectors 791 VA Detector ( ) Amperometric Detector for Ion Chromatography. Electrochemical (amperometric) detection with the 791 VA Detector is a very sensitive detection method used successfully in both HPLC and ion chromatography. This method is also characterized by its very high selectivity: Only easily oxidizable or reducible substances are detected chloride or sulfate are not detected and do not interfere with the electrochemical determination, even in high concentrations. The detector can be used in series or in parallel with other detectors that are frequently used in IC or HPLC (e.g. conductivity or UV/VIS detectors). Numerous electrodes suitable for each amperometric application are available. 871 Advanced Bioscan ( ) Pulsed amperometric detector for the highly sensitive determination of sugars, sugar alcohols and sugar acids, polysaccharides and other oxidizable substances. The 871 Advanced Bioscan extends the IC program from Metrohm by adding carbohydrate analysis to the capabilities of ion chromatography. The heart of the 871 Advanced Bioscan is the pulsed amperometric detector with built-in injector and column heater. The system is controlled by the Metrodata IC Net software. Besides carbohydrates the 871 Advanced Bioscan is used to determine oxidizable inorganic anions. There are different measuring cells with either gold, silver, platinum or glassy carbon as electrode material available. 66 IC

68 Professional IC Hyphenated Technologies Professional IC Hyphenated systems IC Hyphenation The capabilities of ion chromatography is expanded considerably when Metrohm IC is coupled with other analytical methods, sample preparation techniques or detection systems. The possibilities are practically unlimited. Any system which can process aqueous solutions as samples or which provides the same can be coupled with Metrohm IC instruments. Thus, for example, ion chromotography can be combined with Metrohm titrators and measuring instruments as hyphenated systems. These TitrIC systems enable users to determine the complete range of relevant parameters in water analysis from a single sample. Additional typical examples are the coupling of the IC with MS or ICP-MS, Combustion IC and air monitoring systems. 67 IC

69 Professional IC Hyphenated Technologies Professional IC Hyphenated systems TitrIC 4 hyphenated IC and titration system (TitrIC 4) TitrIC 4 the Basic System Fully automatic system for the direct measuring of temperature, conductivity and ph; the titrimetric determination of p-value, m-value, calcium and magnesium; and the determination of anions by ion chromatography. The system consists of the 856 Conductivity Module, four 800 Dosino dosing systems, 802 Stirrer (rod stirrer), 905 Titrando, 815 Robotic USB Sample Processor XL and 881 Compact IC pro with sequential suppression and the 850 Professional Conductivity Detector «idetector». TitrIC the power pack for ion analysis. TitrIC 5 hyphenated IC and titration system (TitrIC 5) TitrIC 5 for the complete analysis of anions and cations. Fully automatic system for the direct measurement of temperature, conductivity and ph, the titrimetric determination of the p-value and m-value; and the determination by ion chromatography of cations (including calcium and magnesium) and anions. The system consists of the 856 Conductivity Module, three 800 Dosino dosing systems, 802 Stirrer (rod stirrer), 855 Robotic Titrosampler, one 881 Compact IC pro without suppression and one 881 Compact IC pro with sequential suppression with one 850 Professional Conductivity Detector «idetector» each. TitrIC the power pack for ion analysis. 68 IC

70 Professional IC Hyphenated Technologies TitrIC 6 hyphenated IC and titration system (Titric 6) TitrIC 6 the professional solution with sealed sample vessels. Fully automatic system for the direct measurement of temperature, conductivity and ph; the titrimetric determination of the p-value and m-value; and the determination by ion chromatography of cations (including calcium and magnesium) and anions. The sample changer is equipped with the DisCover function for automatically removing the sample vessel covers. The system consists of the 856 Conductivity Module, three 800 Dosino dosing systems, 802 Stirrer (rod stirrer), one 905 Titrando, one 815 Robotic USB Sample Processor XL and one 850 Professional IC with two 850 Professional Conductivity Detectors «idetectors» for anions (sequential suppression) and cations. TitrIC the power pack for ion analysis. TitrIC 7 hyphenated IC and titration system (TitrIC 7) TitrIC 7 the solution for samples containing particles. Fully automatic system for the direct measurement of temperature, conductivity and ph; the titrimetric determination of the p-value and m-value; and the determination by ion chromatography of cations (including calcium and magnesium) and anions. Particle-containing samples have their particles removed by Metrohm Inline Ultrafiltration prior to determination by ion chromatography. The system consists of the 856 Conductivity Module, two 800 Dosino dosing systems, one 802 Stirrer (rod stirrer), one 855 Robotic Titrosampler, one 850 Professional IC Anion Prep 2 with one 850 Professional Conductivity Detector «idetector» for anions and one 872 Extension Module IC Pump with an additional idetector for cation analysis. TitrIC the power pack for ion analysis. IC-MS and IC-ICP/MS Coupling Combining IC with an electrospray ionization mass spectrometer (ESI-MS) or an inductively coupled plasma mass spectrometer (ICP-MS) solves even complex separation problems while achieving outstanding sensitivities and selectivities. These so-called hyphenated techniques provide valuable information for unambiguous peak identification and are less prone to matrix influences than IC with conductivity detection. 69 IC

71 Professional IC Hyphenated Technologies Combustion IC (Mitsubishi) (CIC) The Mitsubishi Automatic Quick Furnace AQF-100 a combustion preparation station is easily combined with Metrohm ion chromatography equipment. This results in a fully automated combustion system. This opens up a completely new range of samples, from viscous to solid, for fast and accurate elemental analysis. MultiTek Combustion IC (230 V) ( ) The complete Combustion IC system. The 881 Compact IC pro is combined with the MultiTek Horizontal IC manufactured by PAC. This results in a fully automated combustion system. This opens up a completely new range of samples, from viscous to solid, for fast and accurate elemental analysis. MultiTek Combustion IC (110 V) ( ) The complete Combustion IC system. The 881 Compact IC pro is combined with the MultiTek Horizontal IC manufactured by PAC. This results in a fully automated combustion system. This opens up a completely new range of samples, from viscous to solid, for fast and accurate elemental analysis. PILS, Particle Into Liquid Sampler ( ) Particle into Liquid Sampler for the collection of ambient aerosols. Coupling with ion chromatographs allows automatic determination of the ionic composition of the aerosols without requiring additional sample preparation. 70 IC

72 Professional IC Hyphenated Technologies MARGA, Monitor for Aerosols and Gases in Air (MARGA) MARGA is a fully automated online system for the determination of anions and cations in gases and aerosols. The acidic and alkaline gasses are absorbed in water in a «Wet Rotating Denuder» and the aerosols in a «Steam Jet Aerosol Collector» and then analyzed for anion and cation content with two Compact ICs. MARGA is intended for unattended use over a longer period. MARGA is available from Applikon 71 IC

73 Automation in Ion Chromatography 72 IC

74 Automation in Ion Chromatography IC Automation IC Automation Introduction Sample changer Automation in ion chromatography ranges from straight-forward sample intorduction to highly sophisticated combined sample preparation. Sample volumes from a few L up to several ml need to be handled. A number of sample changers for the different application fields are available. The 858 Professional Sample Processor is more than just a sample changer. Equipped with pumps, highpressure valve and Dosino dosing systems, it greatly enhances capabilities in inline sample preparation and liquid handling. Samples such as milk, chocolate, soda lye, biodiesel or strongly polluted wastewater require sample preparation before they can be analysed by IC. The 850 Professional IC together with the 858 Professional Sample Processor offers numerous possibilities for completely automating Inline Sample Preparation, e.g. Ultrafiltration, Dialysis, Preconcentration, Matrix Elimination, Matrix Neutralisation and Inline Calibration. IC Equipment for liquid handling MISP made easy: The IC equipment sets contain all the necessary modules for the relevant sample preparation method. This means that you can be certain that the method will work properly. In addition to the 858 Professional Sample Processor, the 889 IC Sample Center, and the 863 Compact IC Sample the 814 and 815 Sample Processors are available from the titration product line. Metrohm inline sample preparation (MISP) 73 IC

75 Automation in Ion Chromatography Overwiew on IC Automation Positions on sample rack Variable: ml Vials: 148 Fixed rack, with 36 positions Variable: 384 0,7 ml Vials: 96 Variable: ml Vials: 148 Variable: ml Vials: 228 External position yes no no yes yes Sample delivery Dual channel peristaltic pump or 800 Dosino Dual channel peristaltic pump or 800 Dosino Microliter syringe 800 Dosino 800 Dosino Injection valve yes, as Option no yes no no MSB 3x no no 3x 3x Sample volume ml ml ml ml ml «MISP» All techniques Limited selection Limited selection Some techniques Some techniques 74 IC

76 Automation in Ion Chromatography IC automation instruments 858 Professional Sample Processor ( ) The 858 Professional Sample Processor processes samples with volumes ranging from 500 L to 500 ml. Sample transfer is carried out either by using the peristaltic pump of the 850 Professional IC system or by an 800 Dosino. 858 Professional Sample Processor Pump ( ) The 858 Professional Sample Processor Pump processes samples with volumes ranging from 500 L to 500 ml. Sample transfer is carried out either by using the built-in bidirectional dual-channel peristaltic pump or by an 800 Dosino. 858 Professional Sample Processor Pump Injector ( ) The 858 Professional Sample Processor Pump Injector processes samples with volumes ranging from 500 L to 500 ml. Sample transfer is carried out either by using the built-in bidirectional dual-channel peristaltic pump or by an 800 Dosino. Additionally a six-port injection valve is available for sample preparation purposes. 889 IC Sample Center ( ) The 889 IC Sample Center is a robust autosampler for high sample throughput. Optimized for the challenges of modern analytical labs, the 889 IC Sample Center uses the x-y-z principle and a high-resolution dosing for sample introduction. A double needle system allows the use of vials with caps or septa. A PEEK-injector completes the automation of the 889 IC Sample Center. The 889 IC Sample Center is the perfect automation tool when only very little sample is available. 75 IC

77 Automation in Ion Chromatography 889 IC Sample Center cool ( ) The 889 IC Sample Center is the perfect automation tool if only very little sample is available. Additional to the 889 IC Sample Center it is equipped with a cooling function and is therefore the perfect autosampler for biochemical and/or thermally instable samples. 815 Robotic Soliprep for LC ( ) The 815 Robotic Soliprep for Liquid Chromatography is a complete system for the fully automated preparation of samples that have to be dissolved, homogenized, diluted or filtered prior to analysis. The system includes the following instruments: 1 x 815 Robotic USB Sample Processor XL 1 x 136 Polytron with power supply 1 x 772 Pump Unit 2 x 786 Swing Head 2 x 800 Dosino 863 Compact IC Autosampler ( ) The 863 Compact IC Autosampler is the ideal automation solution for routine analysis. Using the 863 Compact IC Autosampler all Metrohm ion chromatographs can be automated. 76 IC

78 Automation in Ion Chromatography Additional Sample Processors for the IC Even more choice and flexibility! MagIC Net allows users to run USB Sample Processors from our titration portfolio. This translates into virtually unlimited capabilities in automating your ion chromatographic analyses. Whether small or big sample beakers, whether at room temperature or under cooling conditions, whether you use a sample processor with one or two towers, our answer to your demands in ion chromatography always is: Yes, we can! The benefits of using a sample processor are not limited to saving time: Automated systems control repetitive operation steps improving both reproducibility and accuracy. Errors can be almost completely eliminated. Day or night, your sample series are processed with maximum precision. Whether automated sample preparation, liquid handling or sample analysis this new generation of sample processors features capabilities hitherto available only in robots. Apart from MagIC Net and depending on your preferences the USB Sample Processor can also be controlled by Touch Control, PC Control or by our titration software tiamo. Ordering information USB Sample Processor (1T/1P) USB Sample Processor (1T/2P) USB Sample Processor (1T/0P) USB Sample Processor (2T/2P) USB Sample Processor (2T/4P) USB Sample Processor (2T/0P) Robotic USB Sample Processor XL (1T/1P) Robotic USB Sample Processor XL (1T/2P) Robotic USB Sample Processor XL (1T/0P) Robotic USB Sample Processor XL (2T/2P) Robotic USB Sample Processor XL (2T/4P) Robotic USB Sample Processor XL (2T/0P) Robotic Flexible Soliprep Robotic Filtration Soliprep MultiTek Autosampler 10 L (230 V) MultiTek Autosampler 10 L (110 V) MultiTek Autosampler 25 L (230 V) MultiTek Autosampler 25 L (110 V) 814 USB Sample Processor with sample rack for 12 x 250 ml 77 IC