Multi-element analysis of human liver and pig liver and kidney

Transcription

1 Doloded fro orb.d.dk o: Dec 20, 20 l-elee lyss of h lver d pg lver d kdey Forskgsceer Rsø, Rosklde; Plgre Jese, F.; Tscherg øller, J.; Hse, G. Pblco de: 5 Doce Verso Pblsher's PDF, lso ko s Verso of record Lk bck o DT Orb Co (APA): Kep, K., Plgre Jese, F., Tscherg øller, J., & Hse, G. (5). l-elee lyss of h lver d pg lver d kdey. (Rsø-; No. 1822). Geerl rghs Copyrgh d orl rghs for he pblcos de ccessble he pblc porl re reed by he hors d/or oher copyrgh oers d s codo of ccessg pblcos h sers recogse d bde by he legl reqrees ssoced h hese rghs. sers y dolod d pr oe copy of y pblco fro he pblc porl for he prpose of prve sdy or reserch. Yo y o frher dsrbe he erl or se for y prof-kg cvy or coercl g Yo y freely dsrbe he RL defyg he pblco he pblc porl If yo beleve h hs doce breches copyrgh plese coc s provdg dels, d e ll reove ccess o he ork edely d vesge yor cl.

2 A. E.K.Rsø Rsø--EILJ v Te d hor(s) De l-elee Alyse d Kdey f L«5rT.er c grop -.'-r : -- e ver: I cy R,, r-.er, r. r^grer. er.f< v,... d 'jvr- r.r.ser. -_e -., : :.V^xc: Grop s o regsro ber(s) Absrc peges + bles + sos Copes o Or erler developed [] prepro echr.-je f: r l-eleer. lyss of r lver sse by?r--:r. dced X-ry esso specroscopy?'.'az.; s '-sed OR pg lver d kdey d h lver. The deeco ls d he reprodcbly,-,-f sres fro he s,e org ere he se s erler. Oly As d H shoed gre vros h he se org. The vesgo dd o elcde heher hese vros ere de o relly dffere dsrbo of hese elees or o experel er lke erler vesgos [ <] or esrees! ehoed relvely sll vros hr. he se org (5- per ce) of he cocero of os elees h lver. v <: I The Poyl Veerry d Agrclrl versy, Derk, Depre of Phrcology d Toxcology Avlble o reqe fro h«lbrry of he Deh Aoc Eergy Coeeo (Aoeergkoeeoef Bboek), Re#, BK-000 Roeklde, Derk ^^.^. / «««1 rl ~ A fl AlH

3 ge 1. Irodco 2 2. Sples 2. Experes d resls 2. Dscsso Ackovledgees I Refereces W Tbles W 8? W 1

4 2 1. Irodco Or erler vesgos [l] hve sho h lyss by proo-dced I-ry esso (PIXE) s very sble for deero of he eleel coe of r lver. Sleosly, ll elees hever h slco c be deered coceros do o 05 PP dry sse. The reprodcbly of he resls fro ffere prs of he se org s good for ll he elees deered, eve f oly pproxely 1/2 sg s sed for he lyss. Ths repor descrbes exeso of he vesgos o coprse pg lver d kdey d h lver. The prpose of he vesgos s o es he ehod of prepro o oher ypes of sse, d o exe he hoogeey of hese ypes of sse. 2. Sples Lver d kdey sples ere ke fro pgs, ll eghg pprox. 60 kg he slghered. Feedg hd bee orl. The lver secos ere ke fro he cere of he orgs. The kdey secos ere ke fro he cere zoe of he rel corex. The h lver sples orged fro for feles d for les decesed ges of 0-0 yers Copehge. The secos ere ke fro«he cere of he lver«. Experes d resls Fro ech org e.60 r hck, self-spporg, freeze-dred cryos secos [l] ere lysed. These lyses ere perfored order o deere he e vle d he vros s he cocero of he elees h he se org. I ddo,oe 2 hck sple fro ech org s sed for deer' o of he e hckess of he correspodg 60 r secos by coprg he cocero of Fe, C, Z, d Rb he o ypes of sple. Hesrees of he eergy loss of scered proos ere lso perfored order o check he hckess vros. Fro he devos of he resls (bles 1-) s esed h he hckess vros h he se org ere less he % The e hckess of secos fro

5 k dffere orgs Tred fro ^ o dl, probbly de o dffere djses of he ocrooe he dffere secogs. The procedre for deerg he es d vros of he seco hckess hs erler bee descrbed del [l]. The resls of he lyss re sho bles 1-, hch clde coceros of ech elee fro«ech org, he correspodg eed experel cery d sdrd devo (scer of he resls rod ose ele cocero fro ech org) For erly ll elees he scer of he resls c be expled by he eperel cery. Oly he sdrd devos of N d As coceros re cosderbly greer h he ceres. The vles of he sdrd devos for hese elees ere 5% d 5C> for ll orgs lysed. These vles re pproxely ce he correspodg cer. I he r lver lyss [l} N s o clded, b he As coe deered shoved o sdrd devo greer h he ceres, h he se org. The dfferece beee he resls for rs d or e resls gh be csed by fe srcre he orgs. Hoever, s o possble o exclde he occrrece of coo (e.g. fro he secog kfe) hese esrees. rdo vro esed s he sqred s of he sdrd devos of pg lver ed kdey resls (cf. ble ). Ths dces correlo he coe of he o orgs fro he se l. The grees dfferece he coceros of he se elee fod for Se; lso S, CI, C, d shoed ros dfferg fro oe. The possbly of sg sll sples ( < lg e egh) o represe s hole h org hs bee vesged by Schch e l. [2]. The sdrd devos ere deered by lyss of gre ber of sples fro ech org. The devo for lver s fod o be pproxely for Co, Fe, Se, ed Z. Ths s cosderbly greer h he vles lsed bove (ble J). Ackoledgees Thks r de o he Dsh Agrclrl d Veerry Reserch Cocl for he fcl sppor of he projec, d o he Nels Bohr Ise, Copehge vfor plcg he V de Qreff cceleror or dsposl for he vesgos. k. Dscsso l order o copre he coe of elees dffere ypes of orgs, s clcled he e vles d he sdrd devos of he lyss resls fros ech ype of org (ble <0. De o he bove eoed resos he resls for N d As re oed he coprso. A rerkble reseblce s fod beee he coes of os elees he dffere orgs. The dffereces he sdrd devos (slles r d grees h sse) c be expled by he very for feedg of r, he less for feedg of pgs, ed he vred sg hbs of hs. The vro of he Pe coe s probbly de o dffereces he o of blood reed he sse. Keher he prevosly observed correlo beee Fe, As d 8«[l], oher correlo beee elees, s observed h d pg sse. The ros beee he cocero of he sgle elees l jg- kdey d lver rs sho ble 5, I s ss h he clcled sdrd devos re os cses sller h expeced fro he Refereces 1. K. Kep, T. Plgre Jese, J. Tscheg Heller, d 0. Hse, Rse--52 (2) (Dsh Aoc Eergy Cosso) 2. H. Schch, X. Ksperek, L.E. Feedege, V. Sller, sd H.J. Kle, Ber. Ph. $$ (2)

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