Elizabeth A. Ilardi, Ph.D.

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1 HIGHLIGHTS OF QUALIFICATIONS University teaching experience ranging frm instructing general/rganic chemistry lectures and supervising general/rganic chemistry lab classes t the verseeing f undergraduate students in their pursuit f individual research prjects Develped an extensive drug database and several educatinal psters directed at shwcasing ver 2000 pharmaceuticals and their disease categries Cmpetency in utilizing several nline educatinal tls In-depth understanding f synthetic rganic chemistry including the develpment f several ttal syntheses and methdlgies Authr f several peer-reviewed publicatins CURRENT POSITION, Clinical Assistant Prfessr University f Texas at Austin, Austin, TX January 2015 Present Research Educatr fr the Biactive Mlecules research stream in the Freshman Research Initiative Students are enrlled in Students are enrlled in a year-lng research-based curse, where they begin t learn general labratry techniques in rganic chemistry. Ultimately, students will be given unique research prjects fcused n the design and synthesis f mlecules t test as ligands fr varius prteins f interest. Current research prjects are fcused n the ratinal design and synthesis f libraries f small mlecules that bind t medicinally relevant prteins and/r enzymes. The gal f research bjectives is t better understand the thermdynamics f ligand-prtein interactins, using prtein-mdeling prgrams and practical applicatins f isthermal calrimetry (ITC). EDUCATION University f Califrnia Santa Barbara, Santa Barbara, CA May June 2011 Ph.D. in Organic Chemistry Research Advisr: Assciate Prfessr Armen Zakarian Thesis Title: Cascade Rearrangements, New Halgenatin Methds, and Applicatins in Natural Prduct Synthesis Flrida State University, Tallahassee, FL August May 2008 Research Advisr: Prfessr Armen Zakarian The Cllege f William & Mary, Williamsburg, VA August May 2006 Bachelr f Science in Chemistry, minr in Hispanic Studies

2 Page 2 ADDITIONAL RESEARCH EXPERIENCE University f Arizna, Tucsn, AZ Octber 2011 August 2014 Pst-dctral Research Assciate in Organic Chemistry, Natural Prduct Synthesis Research Advisr: Assciate Prfessr Jn T. Njardarsn Research and Educatinal Prjects: Ttal synthesis f the plycyclic plyprenylated acylphlrglucinl (PPAP) natural prduct, hyperfrin, using an xidative dearmatizatin strategy. Disease-Fcused Pharmaceutical Psters: Management f a team f graduate/undergraduate students in the develpment f a first f its kind visual database f pharmaceuticals (~2000, ttal) apprved by the U.S. FDA since its establishment. Each thematic pster (14, ttal) displays a cllectin f drugs (including structural image, FDA apprval date, INN, initial market name, and clr-cded subclass f functin) rganized chrnlgically and classified accrding t an assciatin with a particular clinical indicatin r structural similarity. University f Califrnia, Santa Barbara, Santa Barbara, CA May 2008 June 2011 Graduate Research Assistant in Organic Chemistry, Natural Prduct Synthesis Research Advisr: Assciate Prfessr Armen Zakarian Research Prjects in Ttal Synthesis and Develpment f New Synthetic Methdlgies Develped a cncise and highly diastereselective ruthenium-catalyzed prcess fr the radical chlralkylatin f N-acylxazlidinnes that was extended t the synthesis f bilgically active trichlrmethylated metablites including dysidenin, nedysidenin, dysidin, and barbamide. Cmpleted tw enantiselective ttal syntheses f related alkalids (-)-jubertinamine and (-)-mesembrine relying n an efficient cnsecutive sigmatrpic rearrangement strategy. TEACHING EXPERIENCE CH204 Intrductin t Chemical Practice-FRI UT Austin, 4 semesters, Labratry techniques in rganic chemistry and bichemistry Fall Semester, crss listed curse with Upper Divisin Chemistry Research (CH369K), Organic Chemistry Labratry (CH220C), and Upper Divisin Bilgy Research (BIO377)

3 Page 3 CHEM1C. General Chemistry Lecture III UCSB, Summer 2011 Selected tpics: Chemical bnding, liquids and slids, prperties f slutin, structure and dynamics f elements and their cmpunds. Aspects f technlgy and envirnmental prblems. CHEM 6BL. Organic Lab II UCSB, 7 quarters, Undergraduate rganic labratry methds. CHEM 6CL. Advanced Organic Lab III UCSB, 1 quarter, 2010 Advanced undergraduate labratry methds fr chemistry majrs. Undergraduate Student Mentr: CHEM 6BH/CHEM 6CH UCSB, 2 quarters, 2009 Supervisin f undergraduate research intended fr hnrs students in chemistry. CHEM 6AL. Organic Lab I UCSB, 3 quarters, Intrductry undergraduate rganic labratry methds. CHM2211L. Organic Lab I/II FSU, 1 semester, 2007 Undergraduate rganic labratry methds. CHM2211. Recitatin in Organic Chemistry I and II FSU, 2 semesters, Undergraduate rganic chemistry curse fr science majrs. CHM1045L. General Chemistry Lab II FSU, 1 semester, 2006 Intrductry general chemistry analytical methds fr science majrs. CHEM353. Organic Chemistry Lab II W&M, 2 semesters, Undergraduate rganic labratry methds. HISP208. Upper Intermediate Spanish Cnversatin Drill W&M, 4 semesters, Undergraduate intermediate Spanish cnversatin. CHEM103. General Chemistry Lab I W&M, 2 semesters, Intrductry general chemistry fr science majrs. Undergraduate Research mentr in rganic synthesis present Private tutr fr general and rganic chemistry 2004 present PHARMACEUTICAL EDUCATIONAL POSTERS Disease-Fcused Pharmaceutical Psters 2013

4 Page 4 14 Drug Psters, including: Anti-Infective, Cardivascular System, Nervus System, Sensry Organ, Dermatlgical, Onclgical, Respiratry System, Muscul-Skeletal, Genit-Urinary and Sex Hrmne, Endcrine System, Bld and Bld Frming Organs, and Alimentary Tract and Metablism, Flurinated Pharmaceuticals and Sulfur Cntaining Pharmaceuticals Available as dwnladable PDF files free f charge at: Tp200 Pharmaceutical Drug Psters 4 Psters: Brand Name Drugs by US Retail Sales and by Ttal US Prescriptins 2011, 2012 Available as dwnladable PDF files free f charge at: PUBLICATIONS (10) Ilardi, E. A.; Njardarsn, J. T. Cncise Ttal Synthesis f Hyperfrin, manuscript in preparatin. (9) Ilardi, E. A.; Vitaku, E.; Njardarsn, J. T. Data-mining fr Sulfur and Flurine: An Evaluatin f Pharmaceuticals T Reveal Opprtunities fr Drug Design and Discvery J. Med. Chem. 2014, 57, *LISTED IN THE TOP 20 MOST READ ARTICLES IN THE LAST 12 MONTHS* (8) Ilardi, E. A.; Njardarsn, J. T. Ring Expansins f Vinyl- Oxiranes, Thiiranes, and Aziridines: Synthetic Appraches, Challenges, and Catalytic Success Stries J. Org. Chem. 2013, 78, (7) Ilardi, E. A.; Vitaku, E.; Njardarsn, J. T. An In-Pharm-ative Educatinal Pster Anthlgy Highlighting the Therapeutic Agents That Chrnicle Our Medicinal Histry J. Chem. Educ. 2013, 90, (6) Ilardi, E. A.; Zakarian, A. Efficient Ttal Syntheses f Dysidenin, Dysidin, and Barbamide Chem. Asian J. 2011, 6, (5) Beaumnt S.; Ilardi E. A.; Tappin, N.; Zakarian A. Marine Txins with Spirimine Rings: Ttal Synthesis f Pinnatxins Eur. J. Org. Chem. 2010, *COVER ARTICLE* (4) Beaumnt S.; Ilardi E. A.; Mnre, L. M.; Zakarian A. Valence Tautmerism in Titanium Enlates: Catalytic Radical Halalkylatin and Applicatin in the Ttal Synthesis f Nedysidenin J. Am. Chem. Sc. 2010, 132, (3) Ilardi, E. A.; Stivala, C. E; Zakarian A. [3,3]-Sigmatrpic Rearrangements: Recent Applicatins in the Ttal Synthesis f Natural Prducts Chem. Sc. Rev. 2009, 38, (2) Ilardi, E. A.; Isaacman, M. J.; Qin, Y. C.; Shelley, S.; Zakarian A. Cnsecutive Sigmatrpic Rearrangements in the Enantiselective Ttal Synthesis f (-)-jubertinamine and (-)-mesembrine [Dubis Tetrahedrn Prize Award special issue] 2009, 65, 3261.

5 Page 5 (1) Ilardi, E. A.; Stivala, C. E.; Zakarian A. Hexaflurisprpanl as a Unique Slvent fr Stereselective Iddesilylatin f Vinylsilanes Org. Lett. 2008, 9, 1727.