Dr. Jeremiah A. Johnson

Transcription

1 Dr. Jeremiah A. Johnson Department of Chemistry Massachusetts Institute of Technology 77 Massachusetts Avenue, Room 18-XXX Cambridge, MA XXX-XXX-XXXX (lab) XXX-XXX-XXXX (fax) EMPLOYMENT Assistant Professor of Chemistry, Department of Chemistry, Massachusetts Institute of Technology, Cambridge MA, current Beckman Institute Postdoctoral Scholar, Chemistry and Chemical Engineering, California Institute of Technology, Pasadena CA, Advisers: Professor Robert H. Grubbs and Professor David A. Tirrell HONORS & AWARDS Beckman Institute Postdoctoral Scholar at Caltech ( (2009) PhD thesis recognized with Columbia University distinction (2009) Selected to present at the Excellence in Graduate Polymer Research Symposium at the 2009 national ACS meeting in Salt Lake City (2009) Columbia University Hammett Award for most outstanding Ph. D. student in their final year typically reserved for 5 th year students given in 4 th year (2008) American Chemical Society Organic Division Graduate Fellowship (2007) Selected for and attended the Lindau meeting of Nobel Laureates in Lindau Germany (2006) EDUCATION PhD with distinction, Chemistry, Columbia University, New York NY, 4 February 2009 Advisers: Professor Nicholas J. Turro and Professor Jeffrey T. Koberstein BS, Biomedical engineering & second major in chemistry (cum laude), Washington University, Saint Louis MO, 2004 Adviser: Professor Karen L. Wooley RESEARCH EXPERIENCE 2009-Present Postdoctoral Research, California Institute of Technology, Pasadena CA

2 Advisers: Professor Robert H. Grubbs and Professor David A. Tirrell Design of artificial proteins for novel hydrogel materials with potential applications in wound-healing and tissue engineering Application of ROMP for the synthesis of novel branched-brush copolymers for lighttriggered drug delivery applications as well as photodegradable materials for environmentally friendly adhesives and rubbers Design of novel olefin metathesis catalysts containing N-heterocylic carbene ligands linked to fullerenes and/or cyclodextrins for host-guest modulated catalysis, electrochemically modulated catalysis, enhanced E/Z selectivity, water solubility, and enantioselectivity Graduate Research, Columbia University, New York NY Advisers: Professor Nicholas J. Turro and Professor Jeffrey T. Koberstein Combination of click chemistry and controlled polymerization methods for the synthesis of photodegradable and ozone-degradable plastics and polymer gels for drug delivery, tissue engineering, and waste reduction applications Application of strain-promoted click chemistry to the crosslinking of polymer gels in collaboration with Professor Carolyn R. Bertozzi (University of California, Berkeley) Synthesis of polymeric nanocapsules capable of controlled release in response to light Summer 2008 Research Collaboration, Kyoto University, Kyoto Japan Adviser: Professor Koichi Komatsu Synthesis of C 60 fullerene encapsulating H 2 and HD gases for hydrogen storage studies Summers Research Collaboration, The Scripps Research Institute, La Jolla CA Adviser: Professor M.G. Finn Solid-phase peptide synthesis combined with click chemistry for the synthesis of enzymatically degradable hydrogel materials Development of norbornadiene/quadricyclane isomerization as a tool for reversible surface patterning Undergraduate Research, Washington University, St. Louis MO Adviser: Professor Karen L. Wooley Synthesis of fluorinated polymers for application in high-performance anti-fouling coatings

3 TEACHING EXPERIENCE 2010 Guest lecturer, Caltech, Pasadena, CA Guest lectured for Professor Grubbs graduate level polymer course. Lecture titled, The development of click chemistry and its application to materials science Research mentor, Caltech, Pasadena, CA Mentor one full-time post-baccalaureate student, Alan O. Burts, on an NIH PA research supplement to promote diversity in health-related research (January 2010 present) Mentored two Summer Undergraduate Research Fellows (Summer 2010) Participated in Freshman Summer Research Institute (FSRI) program for underrepresented Caltech undergraduates. Guided research towards the development of photodegradable resins and adhesives based on polydicyclopentadiene Graduate Student Mentor, Columbia University, New York NY Teaching organic synthesis and ATRP technique to first year chemistry PhD student Chemistry Department Tutor, Columbia University, New York NY Tutoring more than 20 students in General Chemistry I & II and Organic Chemistry I & II Undergraduate Student Mentor, Columbia University, New York NY Teaching organic synthesis and ATRP technique to two undergraduate chemical engineering students Teaching Assistant, Columbia University, New York NY Lecturing for General Chemistry I & II 2004 Teaching Assistant, Columbia University, New York NY Lecturing and supervising for General Chemistry Laboratory Teaching Assistant, Washington University, St. Louis MO Lecturing and supervising for General Chemistry Laboratory I & II

4 PUBLICATIONS 12 Johnson, J. A.; Lu, Y. Y.; Burts, A. O.; Lim, Y. H.; Finn, M. G.; Turro, N. J.; Tirrell, D. A.; Grubbs, R. H. Clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and -to. J. Am. Chem. Soc. 2011, 133, Johnson, J. A.; Lu, Y. Y.; Burts, A. O.; Xia, Y.; Durrell, A. C.; Tirrell, D. A.; Grubbs, R. H. Drug-loaded, bivalent-bottle-brush polymers by graft-through ROMP. Macromolecules 2010, 43, Johnson, J. A.; Lu, Y. Y.; Van Deventer, J. A.; Tirrell, D.A. Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications. Curr. Opin. Chem. Biol. 2010, 14, Horsewill, A. J.; Rols, S.; Johnson, M. R.; Murata, Y.; Murata, M.; Komatsu, K.; Carravetta, M.; Mamone, S.; Levitt, M. H.; Chen, J. Y.-C.; Johnson, J. A.; Lei, X.; Turro, N. J. Inelastic neutron scattering of a quantum translator-rotator encapsulated in a closed fullerene cage: isotope effects and translation-rotation coupling in H 60 and HD@C 60. Phys. Rev. B. 2010, 82, / /4. 8 Li, Y.; Lei, X.; Jockusch, S.; Chen, J. Y.-C.; Frunzi, M.; Johnson, J. A.; Lawler, R. G.; Murata, Y.; Murata, M.; Komatsu, K.; Turro, N. J. A magnetic switch for spin-catalyzed interconversion of nuclear spin isomers. J. Am. Chem. Soc. 2010, 132, Johnson, J. A.; Turro, N. J., Koberstein, J. T.; Mark, J. E. Some hydrogels having novel molecular structures. Prog. Polym. Sci. 2010, 35, Johnson, J. A.; Finn, M. G.; Koberstein, J. T.; Turro, N. J. Construction of linear polymers, dendrimers, networks, and other polymeric architectures by copper-catalyzed azide-alkyne cycloaddition click chemistry. Macromol. Rapid Commun. 2008, 29, Johnson, J. A.; Baskin, J. M.; Bertozzi, C. R.; Koberstein, J. T.; Turro, N. J. Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem. Commun. 2008, Johnson, J. A.; Finn, M. G.; Koberstein, J. T.; Turro, N. J. Synthesis of photocleavable linear macromonomers by ATRP and star macromonomers by a tandem ATRP-click reaction: precursors to photodegradable model networks. Macromolecules 2007, 40,

5 3 White, M. A.; Johnson, J. A.; Koberstein, J. T.; Turro, N. J. Toward the syntheses of universal ligands for metal oxide surfaces: controlling surface functionality through click chemistry. J. Am. Chem. Soc. 2006, 128, Johnson, J. A.; Lewis, D. R.; Diaz, D. D.; Finn, M.; Koberstein, J. T.; Turro, N. J. Synthesis of degradable model networks via ATRP and click chemistry J. Am. Chem. Soc. 2006, 128, Gudipati, C. S.; Greenlief, C. M.; Johnson, J. A.; Prayongpan, P.; Wooley, K. L. Hyperbranched Fluoropolymer (HBFP) and Linear Poly(ethylene glycol) (PEG) Based Amphiphilic Crosslinked Networks as Efficient Anti-fouling Coatings: An insight into the surface compositions, topographies and morphologies J. Polym. Sci., Part A: Polym. Chem. 2004, 42, PATENTS Johnson, J. A.; Koberstein, J. T.; Turro, N. J. New macromonomers e.g. difunctional macromonomers and star polymer block macromonomers, useful to prepare e.g. degradable polymer model network, hydrogels, tissue scaffolding, nail polish, bags, films and nanoparticles US Patent WO A1, February 7, ABSTRACTS Johnson, J. A.; Burts, A. O.; Lu, Y. Y.; Xia, Y.; Tirrell, D. A.; Grubbs, R. H. Efficient synthesis of doxorubicin releasing brush polymers by graft-through ROMP Abstracts of Papers, 240 th ACS National Meeting, Boston, MA, United States, August 22-26, Burts, A. O.; Johnson, J. A.; Grubbs, R. H. Simultaneous light-induced core degradation and drug release from nanoscopic star polymers prepared by an arm-first ROMP approach Abstracts of Papers, 240 th ACS National Meeting, Boston, MA, United States, August 22-26, Johnson, J. A.; Koberstein, J. T.; Turro, N. J. Construction of degradable end-linked polymer networks using ATRP and click chemistry Abstracts of Papers, 237 th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, Brown, G. O.; Cheng, C.; Gudipati, C. S.; Johnson, J. A.; Powell, K. T.; Wooley, K. L. Nanoscopically-resolved amphiphilic coatings: Treacherous terrain to inhibit biofouling

6 Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, Gudipati, C. S.; Johnson, J. A.; Wooley, K. L. Crosslinked hyperbranched fluoropolymer (HBFP) - poly(ethylene glycol) (PEG) networks as efficient anti-fouling coatings: An insight into the role of surface composition, topography, and morphology Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, Johnson, J. A.; Gudipati, C. S.; Wooley, K. L. Linear poly(pentafluorostyrene) and poly(ethylene glycol) based amphiphilic networks: Novel nanoscopically-resolved selfassemblies with potential anti-fouling applications. Abstracts of Papers, 226th ACS National Meeting, New York, NY, United States, September 7-11, Wooley, K. L.; Gudipati, C. S.; Johnson, J. A.; Gan, D. Kinetically trapped segregated mixtures of hyperbranched fluoropolymers and linear poly(ethylene glycol)s: Treacherous terrain to inhibit biofouling. Abstracts of Papers, 225th ACS National Meeting, New Orleans, LA, United States, March 23-27, 2003.

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