CERTIFICATE. with the organizational units/sites as listed in the annex

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1 CERTIFICATE This is to certify that with the organizational units/sites as listed in the annex has implemented and maintains an Occupational Health and Safety Management System. : Development, production and distribution of pharmaceuticals, chemical products and analytical systems. Through an audit, documented in a report, it was verified that the management system fulfills the requirements of the following standard: BS OHSAS : 2007 Certificate registration no. Date of revision Valid from Valid until Date of certification BSOH DQS GmbH Stefan Heinloth Managing Director Accredited Body: DQS GmbH, August-Schanz-Straße 21, Frankfurt am Main, 1 / 7

2 with the entities Performance Materials Operations (PM-O), Site Operations (SO) and Healthcare Operation (HO) PM-O: Development, manufacture and distribution of basic chemicals, special chemical products and analytical systems. SO: Operating of infrastructure, internal service provider, supply and disposal. HO: Production and distribution of chemicals Sigma-Aldrich Chemie GmbH Industriestrasse Buchs SG Switzerland Development, manufacturing and distribution of Life Science Products Sigma-Aldrich Production GmbH Industriestrasse Buchs SG Switzerland Development, manufacturing and distribution of Life Science Products Merck Display Materials (Shanghai) Ltd. First Floor and Second Floor Area B of 14th Building East Side and 15th building, No. 211 Qinqiao Road, Free Trade Zone Shanghai P. R. China Design, development, manufacture and distribution of liquid crystal materials; distribution of other chemical materials Merck Electronic Materials (Suzhou) Ltd. No. 70, Longpu Road, Industrial Park Suzhou City, Jiangsu Province P. R. China Production of photoresist products, edge bead rinse thinner, remover used for electronic industry. with the above-mentioned certificate. 2 / 7

3 Litec-LLL GmbH Siemensallee 1 Gebäude Greifswald Development and production of phosphors Mainzer Straße Gernsheim Development, production and distribution of chemical products and analytical systems Merck Performance Materials GmbH Rheingaustrasse Wiesbaden Design and development, production and supply of photoresist, liquid crystals and process chemicals for the electronic and printing industry Merck S.L. Polígono Industrial Merck Mollet del Valles (Barcelona) Spain Production and distribution of pharmaceuticals and chemical products Merck Performance Materials SAS Usine de Lamotte 1, Rue du flottage Trosly Breuil France Design, production and sale of colloidal silica Merck Santé S.A.S. 5, rue Clément Ader Calais France Production of chemical products. with the above-mentioned certificate. 3 / 7

4 Merck Santé S.A.S. 10 Av. de Lattre de Tassigny Meyzieu France Production of chemical products and distribution of pharmaceuticals Sigma-Aldrich Co. Ltd. T/A SAFC Second Avenue Heatherhouse Industrial Estate Irvine KA12 8NB United Kingdom Manufacturing of cell culture related critical raw materials for the global health care industry Merck Ltd. Plot 11/1 Marwasodo Usgaon Ponda Goa Development and production of pharmaceuticals and chemical products Merck Performance Materials Pvt. Ltd. Khopoli Site Survey No 109, 110, 112 Savroli Village, Taluka Khalapur, Dist. Raigad Maharashtra Design, development, manufacturing, marketing and sales of silicon resins (polysilazanes and silazanes) and formulations Merck Life Science Private Limited 50 A & 51, 2nd Phase, Ring Road, Peenya Bangalore Manufacturing of filtration equipment and related products for biopharma, process solution, biomonitoring, lab water, bioscience, laboratory testing, validation and compliance services. with the above-mentioned certificate. 4 / 7

5 Sigma Aldrich Chemicals Private Limited # 12, Bommasandra Jigani Link Road Bangalore, Karnataka State Development, manufacture, sales and distribution of specialty and fine chemicals Sigma-Aldrich Israel Ltd. 3 Plaut St., Park Rabin Rehovot Israel Development and manufacture of biochemicals and biological reagents Sigma-Aldrich Israel Ltd Kiryat Hamada St., Har Hotzvim Jerusalem Israel Development and manufacture of biochemicals and biological reagents Shizuoka Site 3330 Chihama, Kakegawa-shi, Shizuoka Development and production of photoresists for IC s and LCD s, other electronics materialsrelated chemical products (developer, thinner, rinse, remover, antireflective coating, adhesion promoter, insulating coating, protecting coating and electronic raw materials), functional coating Merck Serono Co., Ltd. Atsugi Pharma Operations 4050, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa Visual inspection and packaging of pharmaceutical products Atsugi Site 4084, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa Pref Development, production and distribution of chemical products. with the above-mentioned certificate. 5 / 7

6 Merck Ltd. Atsugi Site 4084, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa Pref Distribution of chemical products Onahama Site 51-15, Aza Egoshi, Kurosuno, Izumi-machi, Iwaki-shi, Fukushima Pref Development, manufacture and distribution of chemical products , Pyeongtaekhang-Ro, Poseung-eup Pyeongtaek-shi, Gyeonggi-do Republic of Korea Development, manufacture, marketing, sales and servicing of chemicals Merck Electronic Materials Ltd Hyupdongdanji-gil, Miyang-myeon Anseong-si, Gyeonggi-do Republic of Korea Research, development, production, inspection and testing of light-sensitive materials and related processing chemicals for semiconductor industry SAFC Hitech Taiwan Co., Ltd. No. 15, Luke 3rd Rd. Kaohsiung Science Park Luzhu Dist Kaohsiung City Taiwan Manufacture of chemicals for industrial applications for optoelectronics and semiconductor devices. with the above-mentioned certificate. 6 / 7

7 Merck Performance Materials Co., Ltd. No , 8 & 11, Xinxing Rd., Hu Kuo Township Hsinchu County Taiwan Development and manufacture of photo-resist products and top-layer anti-reflective coating materials No. 39, 39-1, Ching Chien 1st Road Kuan Yin Industrial Park Taoyuan Taiwan Development, manufacture and distribution of chemical products EMD Performance Materials Corp. 788 Chert Quarry Rd. Martin, SC Manufacturing and development of colloidal silica EMD Performance Materials Corp. 110 EMD Blvd. Savannah, GA Design and development, manufacture and distribution of pigments SAFC Hitech Inc Hilldale Avenue Haverhill, MA Design, development and manufacture of high purity chemicals for industrial applications such as optoelectronics and semiconductor devices EMD Performance Materials Corp. 70 Meister Avenue Branchburg, NJ Design and manufacture of photoresist and related chemical products. with the above-mentioned certificate. 7 / 7

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