Primary Progressive Multiple Sclerosis
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1 Primary Progressive Multiple Sclerosis A Detailed Overview Pharmascroll A Pharmascroll Publication This publication is meant to be used only for Pharmascroll clients post subscription.
2 Table of Contents 1. Multiple Sclerosis Definition 8 2. Types of Multiple Sclerosis.10 a. Relapsing Remitting MS...10 b. Secondary Progressive MS.10 c. Primary Progressive MS...11 d. Progressive Relapsing MS Primary Progressive Relapsing MS Defined Causes of PPMS Profile of PPMS Patient Symptoms of PPMS Disease progression and impact on QoL Disease Diagnosis..20 a. Disease diagnosis through symptoms.20 b. Disease diagnosis through medical tests Disease Epidemiology...24 a. US Epidemiology 24 b. UK Epidemiology 25 c. Germany Epidemiology 26 d. Italy Epidemiology..27 e. France Epidemiology 28 f. Spain Epidemiology..29 g. Japan Epidemiology. 30 Primary Progressive Multiple Sclerosis- A Detailed Overview 2
3 10. Factors impacting a physician s prescription decision..31 a. Efficacy.32 b. Tolerability and Safety.34 c. Monitoring Requirements 37 d. Pricing and Reimbursement Disease Modifying Therapies for PPMS..40 a. Laquinimod..40 i. About the Product..40 ii. Patent and Trial Details.41 iii. Impact of Laquinimod 43 b. Ocrelizumab i. About the Product...44 ii. Patent and Trial Details..45 iii. Impact of Ocrelizumab...47 c. Masitinib i. About the Product..48 ii. Patent and Trial Details.49 iii. Impact of Masitinib. 50 d. Lemtrada i. About the Product..51 ii. Patent and Trial Details.52 iii. Impact of Lemtrada e. Qizenday...54 Primary Progressive Multiple Sclerosis- A Detailed Overview 3
4 i. About the Product..54 ii. Patent and Trial Details.55 iii. Impact of Qizenday.57 f. Ibudilast i. About the Product..58 ii. Patent and Trial Details.59 iii. Impact of Ibudilast.. 60 g. Idebenone i. About the Product..61 ii. Patent and Trial Details.62 iii. Impact of Idebenone Drug Attribute Analysis.64 a. Laquinimod...64 b. Lemtrada 65 c. Masitinib.67 d. Ocrelizumab..68 e. Qizenday f. Ibudilast g. Idebenone Other Pipeline Products a. Number of Pipeline Products phase wise b. Number of Companies having other pipeline products phase wise PPMS Market Sizing 79 Primary Progressive Multiple Sclerosis- A Detailed Overview 4
5 a. Laquinimod..79 i. Value sales in PPMS indication..79 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries.80 iv. Patient numbers by key geographies/countries...80 b. Lemtrada...81 i. Value sales in PPMS indication..81 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries.82 iv. Patient numbers by key geographies/countries...82 c. Ocrelizumab.83 i. Value sales in PPMS indication..83 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries.84 iv. Patient numbers by key geographies/countries...84 d. Masitinib i. Value sales in PPMS indication..85 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries.86 iv. Patient numbers by key geographies/countries...86 e. Qizenday.. 87 i. Value sales in PPMS indication.87 ii. Patient numbers in PPMS indication Primary Progressive Multiple Sclerosis- A Detailed Overview 5
6 iii. Value sales by key geographies/countries.88 iv. Patient numbers by key geographies/countries...88 f. Ibudilast i. Value sales in PPMS indication.89 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries 90 iv. Patient numbers by key geographies/countries...90 g. Idebenone i. Value sales in PPMS indication..91 ii. Patient numbers in PPMS indication iii. Value sales by key geographies/countries 92 iv. Patient numbers by key geographies/countries Market Sizing Country Wise 93 a. Global 93 i. Value sales by Brand 93 ii. Patient numbers by Brand..93 b. US...94 i. Value sales by Brand 94 ii. Patient numbers by Brand..94 c. Germany i. Value sales by Brand 95 ii. Patient numbers by Brand...95 d. France...96 Primary Progressive Multiple Sclerosis- A Detailed Overview 6
7 i. Value sales by Brand 96 ii. Patient numbers by Brand...96 e. Italy.97 i. Value sales by Brand 97 ii. Patient numbers by Brand..97 f. Spain. 98 i. Value sales by Brand 98 ii. Patient numbers by Brand..98 g. UK.. 99 i. Value sales by Brand 99 ii. Patient numbers by Brand..99 h. Canada i. Value sales by Brand 100 ii. Patient numbers by Brand..100 i. Australia i. Value sales by Brand 101 ii. Patient numbers by Brand..101 Primary Progressive Multiple Sclerosis- A Detailed Overview 7
Secondary Progressive Multiple Sclerosis
Secondary Progressive Multiple Sclerosis A Detailed Overview Pharmascroll A Pharmascroll Publication This publication is meant to be used only for Pharmascroll clients post subscription. Table of Contents
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