of mass spectrometry

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1 Thermo Scientific 253 Ultra High resolution isotope ratio MS Discover a new world of mass spectrometry Paleoclimatology Atmospheric science Biogeochemistry Petrology

2 Discover the isotopic anatomy of molecules The new 253 Ultra high resolution isotope ratio mass spectrometer revolutionizes the measurement of site-specific and clumped-isotope-ratio analysis of molecules. The 253 Ultra mass spectrometer will enable new discoveries in climate research, biochemistry, forensics, oil and gas exploration. Paleoclimatology Atmospheric science Biogeochemistry Petrology Analysts now get direct access to the conditions under which molecules were formed, transported, stored and degraded.

3 Explore new possibilities Formation temperatures of molecules Degradation processes of molecules Biochemical processes of nitrous oxide Photochemical processes in the atmosphere Metabolic processes in biochemistry

4 Discover the isotopic anatomy of molecules Mass resolving power greater than 30,000 The new 253 Ultra HR-IRMS combines a 10 kv electron impact ionization source, a high-mass-resolution double-focusing magnetic-sector mass analyzer, and a variable collector array. The 253 Ultra HR-IRMS delivers a guaranteed mass resolving power of 30,000. High, medium and low resolution are selected automatically by each method using a switchable entrance slit. Focus quadrupole Zoom lens ELECTROSTATIC SECTOR The electrostatic sector analyzer (ESA) with a radius of 220 mm refocuses the energy dispersion of the ions prior to the magnetic sector. ENTRANCE SLIT The computer-controlled entrance slits can be switched between 5 μm and 250 μm which allows the selection of low, medium and high mass resolution. Modular concept The 253 Ultra HR-IRMS includes two dual viscous flow inlet systems for handling up to 3 reference gases together with the sample. Based on our modular dual inlet design each dual inlet can be exchanged as required to avoid cross contamination depending on the sample types that are being analyzed. 10 KV ION SOURCE The gas tight electron impact ion source with a wide range of adjustable electron energy and variable pumping conductance provides ultra high sensitivity. The ion source preserves clumping and isotopic distribution in the ions because of its low scrambling characteristics.

5 MAGNETIC SECTOR The temperature-controlled, laminated electromagnet has a radius of 230 mm. The overall magnification of the system is a factor of 2, yielding a dispersion of 810 mm. The mass range is up to mass 280 at full acceleration voltage. The mass range can be extended to 560 at reduced accelerating potential and reduced mass resolving power. Ultimate abundance sensitivity The variable collector array covers a dynamic range of signal intensity >10 orders of magnitude, ranging from collection of the more abundant ion beams in Faraday cups to single ion counting of very rare ion species. Very small signals can be analyzed with the axial secondary electron multiplier, which is equipped with our unique RPQ retardation lens for ultimate abundance sensitivity. VARIABLE MULTICOLLECTOR On either side of the fixed axial collector there are 4 moveable detector platforms. Each variable detector platform is equipped with a Faraday detector and in addition can carry a compact discrete dynode (CDD) ion counting detector. In total 9 Faraday cups and 8 ion counters can be installed in the variable collector array. RPQ SEM The axial detector channel is a dual mode detector with a Faraday cup and a high sensitivity ion counting detector (SEM). In front of the SEM is a retarding potential quadrupole (RPQ) to reduce the abundance sensitivity for measurement of very small ion beams. Q T E D R G I V E N R A B Y S I S D Fully integrated workflow The new Qtegra intelligent scientific data solution revolutionizes the procedures of isotope ratio analysis by fully integrated workflows making high resolution isotope ratio MS a routine tool. Qtegra software combines all experiments related to a specific sample in one lab book organizing data acquisitions, combining and computing data streams, presenting final results of even complex analysis.

6 Discover more with the leader in isotope analysis For over 60 years Thermo Fisher Scientific has been the leading supplier of isotope ratio instrumentation to scientists throughout the world. Our products have enabled some of the most exciting pioneering discoveries with isotopic measurement, many in geochemical applications. The 253 Ultra high resolution IRMS continues the journey by unlocking new possibilities with isotopic measurement. All our products are built to exacting standards, and supported globally by our international service network. Our goal is to ensure your success. Delta Ray isotope ratio infrared spectrometer Delta V isotope ratio MS Thermo Scientific Isotope Ratio Analyzers MAT 253 isotope ratio MS Element 2/XR ICP-MS Helix MC Plus noble gas MS Triton Plus thermal ionization MS Neptune Plus high resolution MC-ICPMS 253 Ultra high resolution isotope ratio MS , 2015 Thermo Fisher Scientific Inc. All rights reserved. ISO is a trademark of the International Standards Organization. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries. This information is presented as an example of the capabilities of Thermo Fisher Scientific products. It is not intended to encourage use of these products in any manners that might infringe the intellectual property rights of others. Specifications, terms and pricing are subject to change. Not all products are available in all countries. Please consult your local sales representative for details. Thermo Fisher Scientific (Bremen) GmbH Management System Registered to ISO 9001:2008 Africa Australia Austria Belgium Canada China (free call domestic) BR30293-EN 01 15G Denmark Europe-Other Finland France Germany India Italy Japan Korea Latin America Middle East Netherlands New Zealand Norway Russia/CIS Singapore Spain Sweden Switzerland UK USA