Chemistry 250: Reactivity 1

Transcription

1 Chemistry 250: Reactivity 1 Spring 2013 Tentative Even Day Class Schedule Resources Workbook: Principles of Reactivity 1 Available in the CSB Bookstore Text: Choose one or more of the following options: 1. Chemistry 250 Custom Book -- shrink-wrapped with 2 passcodes (strongly recommended) Note answers are available for organic in-chapter problems and biochem end of chapter problems within your text Note answers for the inorganic chapters and some organic (end of chapter problems) are available on the NMR Moodle page 2. Online Text (Structure & Reactivity, Part III, available at: ( ) OR if desired a softcover copy of online textbook: ( ct_page.html?slug= _58_488) Online homework passcodes: (ONLY if you didn t buy text with passcodes) o Two Passcodes: 1) Hornback & 2) Garrett & Grisham: ( OWL with Cengage 24 months Instant Access Code for Garrett/Grisham's Biochemistry, 5th Ed ISBN-10: ISBN-13: $ OWL (24 months) Instant Access Code for Organic Chemistry, 1st Edition ISBN-10: ISBN-13: $74.00 o There may be students from Fall 2012 Chem 251 with extras that will sell at a discount.

2 Getting Started on OWL Chemistry 250 There are 2 separate online passcodes you will need to use, so you will need to go through the following procedure twice. On the web, go to: In the box labeled Instructor/Student Login, click on: Organic Or Biochemistry Go through the books and choose: Organic Chemistry, 2 nd Ed; Hornback Or Biochemistry, 5 th Ed; Garrett&Grisham Go through the list of schools and choose: College of Saint Benedict - Saint Joseph, Minnesota Select: Student registration Select: Chemistry 250 Spring 2013 with Instructor Name Make sure you select the correct section! Choose your own loginid and password and enter the access code you bought with your book Two Notes: These passcodes will be good for all next year (DON T throw them away!) and you will have to re-register each semester. We will begin using the organic passcode in January and the biochemistry passcode in March Keep them in a safe place!

3 Anionic Nucleophilic Additions to Carbonyls Tuesday, January 15, Day 2 Overview First-Day Overview of Class Structure o Roster o Syllabus and Course Outline Group work and Pedagogical Theory Assign Groups In class: Nu Additions Introduction to Anionic Nucleophilic Additions to Carbonyls o Mechanism, Workbook: 3-9 o Acetylides, Cyanides and Grignards, Workbook: Note Upcoming Deadline: OWL Review Packet 1: Due Jan 23 Ch 1: Chemical Bonding Ch 2: Organic Structures and Electrostatics Ch 3: MO Ch 4: Acid-Base Ionic Radii Resonance Structures OWL Review Packet 2: Due Feb 12 Ch 7: Stereochemistry Ch 16: Aromaticity Chapter 5/12: Nomenclature: OWL 5bdghi, 12bd MLK Extra Credit: Percy Julian (Due Thursday, Jan 23) Tuesday, January 15 6:30-8:00 pm Faculty Tutorial, O Connells

4 Percy Julian Extra Credit Assignment (10 points) Extra Credit Assignment: Percy Julian 1) Watch PBS Nova movie, Forgotten Genius on-line: 2) After watching the movie, follow at least one related interactive link at the bottom of the PBS Julian website. 3) Write a response to the movie and website (2-3 pages): a. Summary of Percy Julian s scientific achievements b. Mention of the obstacles that Percy Julian faced c. Discussion of the link that you followed d. Brief Conclusion with a personal response regarding something that you learned 4) Due Tuesday, January 22 nd.

5 Thursday, January 17, Day 4 Preparation: Nu Additions o Reactivity 1 text: Chapter 18. Additions to the Carbonyl Group 18.1 General Mechanisms o Structure & Reactivity online text: CO1-CO4, CO6 o Reactivity 1 text: Chapter 18. Additions to the Carbonyl Group 18.2 Addition of Hydride 18.4 Addition of HCN 18.5 Preparation and Properties of Organometallic Nucleophiles 18.6 Addition of Organometallic Nucleophiles o Structure & Reactivity online text: CO7-CO8, CO16 o Reactivity 1: 18.1, 18.2, 18.6, 18.8, 18.9, NOTE: Answers are found in NMR Moodle Site o Structure and Reactivity: CO , CO , CO , CO4.1, CO NOTE: Answers are found in CO22 o Introduction to OWL: How to Complete and Submit Assignments o OWL: 18a (Tutor, Carbonyl Reactions) o Passport: Practice problems Structure and Reactivity: CO1.1, CO5.1, CO8.1 In class: Nu Additions Anionic Nucleophiles o Hydrides, Workbook: o MO of Nucleophilic Addition, Workbook, o Chiral Hydrides, Workbook: o Practice, Workbook: o Sample Notecards, Workbook: 23

6 Thermodynamics Monday, January 21, Day 6 Preparation: Thermodynamics of Reactions o Reactivity 1 text: Chapter 6.2 Two Keys to Stability of TM Complexes o Structure & Reactivity online text: TD1-TD3 o Structure & Reactivity, Part III: TD 1.1, 2.1, 3.1, 3.2, 3.3 NOTE: Answers are found in TD7 o Group Assignment: Bio Hydrides, Roadmap Practice, Workbook: o Passport: Bring Notecards of new reactions, Workbook: 22 o OWL: 18b, 18c, 18d In class: Thermodynamics Enthalpy, Workbook: BDE, Workbook: Reaction Diagrams, Workbook: Enthalpy of Reactions, Workbook: 45 PSA#1

7 Wednesday, January 23, Day 2 Preparation: Thermodynamics of Reactions o Structure & Reactivity online text: TD1-TD3 o Structure & Reactivity, Part III: TD 1.1, 2.1, 3.1, 3.2, 3.3 NOTE: Answers are found in TD7 o Group Assignment: Bond Energy, Workbook: o OWL: Review Packet #1 o MLK day Extra Credit: Percy Julian In class: Thermodynamics Entropy, Workbook: Free Energy, Workbook: Tuesday, January 22 6:30-8:00 pm Faculty Tutorial, O Connells

8 Reversible Nucleophilic Additions to Carbonyls Friday, January 25, Day 4 Preparation: Nu Additions o Structure & Reactivity online text: TD5, CO5, CO6 CO10-CO13 o Organometallic HyperText: Microscopic Reversibility o Reactivity 1: CO , CO , CO NOTE: Answers are found in CO22 o Group Homework, Organic Nomenclature: Workbook: o OWL: Introduction to Thermodynamics In class: Nu Additions Reversibility, Workbook: Tuesday, January 29, Day 6 Preparation: Nu Additions o Reactivity 1 text: Chapter 18. Additions to the Carbonyl Group 18.8 Addition of Nitrogen Nucleophiles o Structure & Reactivity online text: CO14-CO15, SC8, SC11 o Reactivity 1: 18.3, NOTE: Answers are found in NMR Moodle Site o OWL: 18g (Acetal Tutor), Microscopic Reversibility In class: Nu Additions Nitrogen Neutral Protic Nucleophiles, Workbook: Oxygen Neutral Protic Nucleophiles, Workbook: PSA#2 Tuesday, January 29 6:30-8:00 pm Faculty Tutorial, O Connells

9 Thursday, January 31, Day 2 Preparation: Nu Additions o Structure & Reactivity online text: TD6 o Structure & Reactivity, Part III: TD 5.1, 5.2, 5.3, 5.4 NOTE: Answers are found in TD7 o Structure and Reactivity: CO5.1, CO , CO11.1, CO NOTE: Answers are found in CO23 o Group Homework: practice problems Reactivity 1 text: 18.16, 18.17, 18.21, 18.22, o Passport: Finish all mechanisms for o OWL: 18f, 18g, 18h, 18j In class: Nu Additions Thermodynamics of Reversible Rxns, Workbook: Practice, Workbook: 81-86

10 Coordination Compounds Monday, February 4, Day 4 Preparation: Ligand Binding o Reactivity 1 text: Chapter 2.3 Modern View of CC compounds Chapter 2.4 An Introduction to Nomenclature Chapter 6.2 Two Keys to Stability of TM Complexes o Structure & Reactivity online text: CC1-CC7 o Organometallic Reader: Simplifying OM Complexes Part I Part II Part III o Organometallic Hypertext: Denticity Electron Counting o Structure & Reactivity, Part III: CC , , o NOTE: Answers are found in CC11 o Group Homework, Workbook: o Individual Homework on Nomenclature: Workbook: o OWL: Review Packet 2 Due (Stereochemistry and Organic Nomenclature) In class: Ligand Binding Hapticity, Workbook: Hard-Soft Acid-Base Workbook: Practice Workbook:

11 Wednesday, February 6, Day 6 Preparation: Ligand Binding o Structure & Reactivity, Part III: CC o NOTE: Answers are found in CC11 o Group Homework: Review CCmpds: Workbook: o OWL: Electron Counts on Coordination Compounds, d electrons, Geometry of Coordination Compounds, Inorganic Nomenclature, Hard-Soft Acid Base o Passport on Fuel Cells, Workbook: 119 How Fuel Cells Work Fuel Cells Explained In class: LIgand Binding Metal Organic Frameworks, Workbook: Tuesday, February 5 6:30-8:00 pm Faculty Tutorial, O Connells

12 Ligand Field Theory Friday, February 8, Day 2 Preparation: o Reactivity 1 text: Chapter : Bonding Theories for Coordination Cmpds, p o Structure & Reactivity online text: CC8-CC9 o Organometallic Reader: Ligand Field Theory o Reactivity 1: Ch 2 #25-28 Note: Answers available (NMR Moodle site) o Group Homework: Workbook: o Individual Passport, MO Review: Workbook: In class: Crystal Field Theory d orbital shapes and ligand field theory, Workbook, Feb PSA Tuesday, February 12, Day 4 Preparation: o Reactivity 1 text: Chapter 4: Bonding Theories for Coordination Cmpds o Structure & Reactivity online text: CC8-CC9 o Reactivity 1: Ch 4 #9, 11, 15, 21, 25, 27, 37, 43 Note: Answers available (NMR Moodle site) o None In class: Ligand Field Theory Field Splitting, Workbook, Metal Ion Effects, Workbook, Ligand Effects, Workbook, Tuesday, February 12 6:30-8:00 pm Faculty Tutorial, O Connells

13 Thursday, February 14, Day 6 Preparation: Ligand Field Theory o Reactivity 1 text: Chapter 4.3 (p 69-86) o Structure & Reactivity online text: CC8-CC10 o Reactivity 1: Ch 4 # Ch 4, # 31, 39, 47 Note: Answers available (NMR Moodle site) o Individual Passport: LFT Summary, Workbook: 154 o OWL: Octahedral Spin, Metal Ion Effects, Spectrochemical 1 and 2 In class: Ligand Field Theory Splitting for non-octahedral, Workbook PSA#3 Monday, February 18, Day 2 Preparation: Ligand Field Theory o UCDavis ChemWiki CFT Summary CFT Summary Note: This site has problems with answers o Reactivity 1 text: Chapter 4.3 (p ) o Structure & Reactivity, Part III: CC , , NOTE: Answers are found in CC11 o Reactivity 1: Ch 4 # Ch 4, # 53, 55, 57 Note: Answers available (NMR Moodle site) o Group Homework: Square Planar Fun, p In class: Ligand Field Theory Lability Workbook, Magnetism, Workbook, UV, Workbook, Applications, Workbook, Introduction to Catalysis Wednesday, February 20, Day 4 Preparation: Catalysis o Structure & Reactivity online text: RK8

14 o Catalysis and Reaction Energetics o Structure & Reactivity, Part III: o Group Homework: Magnetism, o OWL: Ligand Exchange, Magnetic Properties, Magnetic Moments In class: Catalysis Catalysis, Workbook: PSA#4 Tuesday, February 19 No Faculty Tutorial Thursday February th LONG WEEKEND

15 Carbonyl Binding and Migratory Insertion Tuesday, February 26, Day 6 Preparation: Nu Additions o Structure & Reactivity online text: MI1, MI2, MI3 o Organometallic Reader: Carbon Monoxide o Organometallic HyperText: Insertion Reactions o Structure & Reactivity, Part III: TD 6.1, 6.2, 6.3, 6.4, 6.5 NOTE: Answers are found in TD7 o Structure and Reactivity: CO NOTE: Answers are found in CO23 o Individual Passport, Catalysis Summary: Workbook: 218 o Group Homework: LAD, Workbook: In class: Nu Additions Carbonyl Binding and Migratory Insertion, Workbook: PSA#5 Tuesday, February 26 6:30-8:00 pm Faculty Tutorial, O Connells Thursday, February 28, Day 2 Preparation: Nu Additions o Structure & Reactivity online text: MI4, MI5 o Organometallic Insertion Reactions Insertions o Organometallic HyperText: β-hydride Elimination Suggested Problems: o Structure & Reactivity, Part III: MI1-MI5 NOTE: Answers are found in MI6 o Group Homework, Application Problems: Workbook: In class: Nu Additions 1,2-Insertion and β-elimination, Workbook:

16 Nucleophilic Additions to Carbonyls: Part 4 Monday, March 4, Day 4 Preparation: Nu Additions o Reactivity 1 text: Chapter 18. Additions to the Carbonyl Group 18.7 Wittig Reactions o Structure & Reactivity online text: CO18 Suggested Problems: o Structure & Reactivity, Part III: MI1-MI5 NOTE: Answers are found in MI6 o Passport: Insertions and Eliminations, MI5.1, 5.2, 5.3, 5.4 o Group Homework, Instructor Assigned: Workbook: o OWL: 18e (Wittig Tutor), Migratory Insertion In class: Nu Additions Sulfur and Phosporus Ylides, Aldols, Workbook: Wednesday, March 6, Day 6 Preparation: Nu Additions o Reactivity 1 text: Chapter 20: Enolates and Other Carbon Nucleophiles 20.1 Enols and Enolates 20.5 Aldol Condensations o Structure & Reactivity online text: CO9 o Reactivity 1: Wittigs Wittigs: 18.12, 18.13, 18.14, NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CO NOTE: Answers are found in CO23 o Individual Homework, Enolates: Workbook, In class: Nu Additions Applications of Ylides/Enolates to Synthesis, Workbook: 251, Tuesday, March 5 6:30-8:00 pm Faculty Tutorial, O Connells

17 Nucleophilic Substitutions Friday, March 8, Day 2 Preparation: Nu Substitutions Prepare Notecards on Carbonyl Addition Reactions Read o Reactivity 1: Chapter 19. Nucleophilic Additions to Acid Derivatives 19.1 General Mechanism 19.2 Preparation of Acyl Chlorides 19.3 Preparation of Anhydrides 19.4 Preparation of Esters 19.5 Preparation of Carboxylic Acids o Structure & Reactivity online text: CX1-CX4 o Reactivity 1: Wittigs Aldols: 20.2, 20.9, NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CO NOTE: Answers are found in CO23 o Group Homework: Do either of these sets of practice problems Reactivity 1 text: 18.5, 20.9 o Individual Homework, Callystatin, Workbook, 266 o OWL: 20a, 20f, 20g In class: Nu Substitutions Ski Slope, Workbook: March PSA

18 Tuesday, March 12, Day 4 Preparation: Nu Substitutions Read o Reactivity 1: Chapter 19. Nucleophilic Additions to Acid Derivatives 19.7 Reaction with Hydride Nucleophiles 19.8 Reduction of Acid Derivatives to Aldehydes 19.9 Reaction with Organometallic Reagents 20.7 Haloform Reactions o Structure & Reactivity online text: CX5-CX6 o Reactivity 1: NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CX1.1, CX , CX , CX NOTE: Answers are found in CX9 o Passport Homework: Workbook, 273 as notecards o OWL: 19a, 19b (Tutors) In class: Nu Substitutions Substitutions, Workbook: **Register for OWL, Garrett and Grisham, 5 th Ed. Biochemistry Review Packet due March 21 (BIG assignment, LOTS of points PLAN Ahead) Tuesday, March 12 6:30-8:00 pm Faculty Tutorial, O Connells

19 Thursday, March 14, Day 6 Preparation: Nu Substitutions o Reactivity 1: Chapter 19. Nucleophilic Substitutions to Acid Derivatives 20.6 Ester Condensations Derivatives of Sulfur and Phosphorus Acids o Structure & Reactivity online text: CX7-CX8 o Prepare Notecards on Carbonyl Substitution Reactions o Reactivity 1: NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CX , CX NOTE: Answers are found in CX9 o Group Homework: Workbook, Weinreb Amides, o OWL: 19c, 19d, 19e, 19f, 19g o OWL: 20h (Tutor) In class: Nu Substitutions Claisens, Sulfonates, Phosphonates, Workbook: PSA#5

20 Conjugate Additions Monday, March 18, Day 2 Preparation: Nu Substitutions o Reactivity 1: Chapter 20: Enolates Ch Conjugate Addition to Carbonyls Ch Michael Additions and Robinson Annulations o Structure and Reactivity: CO19 Conjugate Addition o Reactivity 1: 19.25, NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CX7.1, 7.2a, NOTE: Answers are found in CX9 o OWL: 20i, 20j In class: Conjugate Additions Conjugate Additions, Workbook: Wednesday, March 20, Day 4 Preparation: o Reactivity 1: Chapter 20: Enolates and Carbon Nucleophiles Ch Michael Additions and Robinson Annulations Ch Synthesis o Reactivity 1: 18.25, 18.26, NOTE: Answers are found on NMR Moodle site o Structure and Reactivity: CO NOTE: Answers are found in CX9 o Group Homework: Helminthosporal Workbook, 306 o OWL: 20k, 20l (preview of enamines), 18j, 18k, 18m In class: Conjugate Additions Robinson Annulations/Stork Enamines, Workbook: Tuesday, March 19 6:30-8:00 pm Faculty Tutorial, O Connells

21 Enzyme Catalysis Friday, March 22, Day 6 Preparation: Enzymes Register for new OWL course using your second passcode. o Campbell and Farrell, Biochemistry o Reactivity 1 text: Chapter 13: Enzymes Kinetics and Specifity 13.1 Characteristic Features 13.4 Inhibition of Enzymes 13.6 Enzyme Specificity 13.7 Are all enzymes Proteins? 13.8 Enzyme Design o Reactivity 1 text: Chapter 14: Mechanisms of Enzyme Action o Enzyme Catalysis Interactive Concepts Chapter 6 o Group Homework, Hinesol: Workbook, 313 o Passport, Catalysis Review: Workbook, o G&G OWL: Biochem Review Packet In class: Enzyme Catalysis Enzymatic Catalysis/Transition State Analogs, Workbook: PSA#6 EASTER Break

22 Metals in Enzyme Catalysis Wednesday April 3, Day 2 Preparation: Enzymes o Reactivity 1 text: Chapter 6.5 Bioinorganic Applications o Chem. Rev., Bioinorganic Enzymology, Vol. 96(7), 1996, pp o Reactivity 1: Mechanisms of Enzyme Actions 14.1, 14.2, 14.7, NOTE: Answers are found on NMR Moodle site o Group Homework: Workbook, HIV Protease, o G&G OWL: 13.1, 13.6, 14.3, 14.6, 14SAS In class: Metals in Biochemical Catalysis Bioinorganic, Workbook: Tuesday, April 2 No Faculty Tutorial, O Connells

23 Biochemical Pathways: Reactions, Thermodynamics and Regulation Friday, April 5, Day 4 Preparation: Pathways o Structure & Reactivity online text: MP1-MP3 o Reactivity 1 text: Chapter 18. Glycolysis Except 18.7 and 18.8 o Glycolysis Biosynthesis Interactive Concepts Chapter 15 o Group Homework: Workbook, o G&G OWL: Ch15, Special Focus on Hemoglobin In class: Glycolysis Glycolysis: A Mechanistic Approach, Workbook: April PSA Tuesday, April 9, Day 6 Preparation: Pathways o Reactivity 1 text: Chapter 19. TCA cycle (Kreb s Cycle) Except 19.6, 19.7 and 19.9 o TCA Cycle Biosynthesis Interactive Concepts Chapter 16 o Reactivity 1: 18.5, 18.9, 18.20, NOTE: Answers are found on NMR Moodle Site o Passport: pages from the Glycolysis section (TBA in class) o G&G OWL: Glycolysis 18.1, 18.3, 18.4 In class: TCA Cycle TCA or Kreb s Cycle: Mechanistic Approach, Workbook: Tuesday, April 9 6:30-8:00 pm Faculty Tutorial, O Connells

24 Thursday, April 11, Day 2 Preparation: Pathways o Reactivity 1 text: Chapter 17. Metabolism An Overview Except 17.4 and 17.5 o Glycolysis Biosynthesis Interactive Concepts Chapter 14 o Reactivity 1: 19.2, 19.4, 19.9, 19.14, NOTE: Answers are found on NMR Moodle site o Passport: page from TCA Cycle section (TBA in class) o Passport: Thermodynamics Review, Workbook, 374 o G&G OWL: TCA Cycle 19.1, 19.3, 19.4, SAS In class: Glycolysis Thermodynamic Control, Workbook: Standard Free Energy Changes, Workbook, PSA#7 Monday, April 15, Day 4 Preparation: Pathways o Reactivity 1 text: Chapter 15. Enzyme Regulation o Structure & Reactivity online text: MP4 o Reactivity 1: 17.4, 17.6, 17.9, 17.14,17.15, 18.1, 18.11, 18.13, 18.14, NOTE: Answers are found on NMR Moodle site o Group Homework: Cumulative Problem, Workbook, o G&G OWL: 3.1, 3.5, 3.6, 3.Self-Assessment (Thermodynamics of Biological Systems) 18.Self-Assessment (Thermodynamics of Glycolysis) o G&G OWL: Gluconeogenesis 22.1 In class: Regulation of Pathways Allosteric Enzyme Regulation, Workbook: Covalent Modification of Enzymes: Workbook:

25 Wednesday, April 17, Day 6 Preparation: Pathways o Covalent Modification: Phosphorylation o Reactivity 1: 15.16, 15.18, 15.20, 17.8, 19.3 NOTE: Answers are found on NMR Moodle site o Group Homework, Workbook, Instructor Choice, , In class: Pathways Fatty Acid Biosynthesis: Mechanistic, Workbook: Tuesday, April 16 6:30-8:00 pm Faculty Tutorial, O Connells Friday, April 19, Day 2 Preparation: Pathways o Fatty Acid Biosynthesis Interactive Concepts Chapter 18 o Structure & Reactivity online text: MP5 o Passport: Workbook, 429 o Group Homework: Workbook, o G&G OWL: 15 Enzyme Regulation 15.1, 15.2, 15.3, 15.5, SAS In class: Pathways Fatty Acid Biosynthesis: Regulation, Workbook: β-oxidation, Workbook: PSA#8

26 Tuesday, April 23, Day 4 Preparation: Pathways o Fatty Acid Biosynthesis Interactive Concepts Chapter 18 o Structure & Reactivity online text: MP5 o G&G OWL: Lipid Biosynthesis 24.1, 24.2 o G&G OWL: Common Catabolic Pathway 27.1 In class: Pathways Ketogenesis, Workbook: Diabetes, Workbook: Tuesday, April 23 No Faculty Tutorial, O Connells Wednesday, April 24 Scholarship and Creativity Day Chemistry and Biochemistry Senior Presentations A list of titles, times and locations will be announced Extra Credit Option Attend one Chemistry or Biochemistry Senior Presentation Write a 1 paragraph summary Due April 26th **Look Ahead Practice Final Exam, Hornback OWL 90 Multiple Choice questions due May 7

27 Polymers Friday, April 26, Day 6 Preparation: Polymers o Frank Harris, J. Chem. Ed., 1981, 58(11), o Case Western Virtual Textbook o OWL: 23 Lipid Catabolism (23.2, 23.3, Self-Assessment) o Extra Credit: Summary of a Senior Presentation In class: Pathways Polymer Architecture, Workbook, Polymer Properties, Handout Tuesday, April 30, Day 2 Preparation: Polymers o Group Homework, Workbook: 462 o Hornback OWL: 24. Nylon Formation Tutor In class: Polymers Polymer Synthesis, Workbook, PSA#19 Tuesday, April 30 6:30-8:00 pm LAST Tutorial, O Connells

28 Thursday, May 2, Day 4 Preparation: Polymers o Protein Biosynthesis Interactive Concepts Chapter 12 Suggested Problems: o Structure and Reactivity: CX NOTE: Answers are found in CX9 o Passport: Transcription Review, o Hornback OWL: Polymers In class: Pathways Protein Biosynthesis, Workbook, Monday, May 6, Day 6 Preparation: Polymers o G&G OWL: Protein Synthesis o OWL: Multiple Choice Practice Final Exam In class: Applications Applications, TBA May PSA Tuesday, May 7: Study Day Final Exam: 8-10 am on Friday, May 9