CHROMTECH - CHIRAL HPLC COLUMNS
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1 CHIRAL HPLC COLUMNS These protein-based columns are suitable for several types of compounds; basic compounds with an extremely broad applicability, this column should be chosen first, if the analyte has not been separated on any of the columns. There are, however, some types of compounds where one of the other columns may be the first choice : Extremely broad applicability. We believe that this chiral phase as one of the broadest analytical selectivities of any chiral phase. Separates all kinds of compounds : CHIRAL-CBH basic nitrogens together with one or more basic nitrogens together with one or more hydrogen accepting or hydrogen donating groups (alcohol, phenol, carbonyl, amide, ether, sulphoxide, ester, etc.). non-protolytic compounds. 47
2 is the second generation chiral separation column based on the use of α 1 -acid α 1 μm). The surface chemistry of the silica proves a stable chiral separation material with extremely broad applicability. derivatization. The column enables resolution of a very large number of chiral compounds from different compound classes. This is due to the unique nature of the CSP, and the fact that enantioselectivity can be induced by choosing a proper mobile phase composition. COLUMNS 5 µm Analytical Analytical Analytical Analytical Analytical Analytical Analytical Analytical Analytical Semi-Prep Semi-Prep (2/pkg) Guard Cartridges (x2) (2/pkg) Guard Cartridges (x2) (2/pkg) Guard Cartridges (x2) 48
3 CHIRAL-CBH - CHIRAL HPLC COLUMNS CHIRAL-CBH μm spherical silica particles creating the Chiral Stationary Phase in the CHIRAL-CBH column. This is also a reverse phase column, used for the direct separation of enantiomers. The column is preferentially used for the separation of the enantiomers of basic drugs from many compound classes. CHIRAL-CBH COLUMNS 5 µm CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Analytical CHIRAL-CBH Semi-Prep CHIRAL-CBH Semi-Prep CHIRAL-CBH (2/pkg) Guard Cartridges (x2) CHIRAL-CBH (2/pkg) Guard Cartridges (x2) CHIRAL-CBH (2/pkg) Guard Cartridges (x2) 49
4 The chiral selector in this stationary phase is human serum albumin (HSA). The protein has been μm particles. Enantiomers of preferentially acidic compounds can be resolved directly, without derivatization. The column is operated in the reverse phase mode. With the column, both racemic acids and amino acids can be resolved directly, without derivatization. COLUMNS 5 µm Analytical Analytical Analytical Analytical Analytical Analytical Analytical Analytical Analytical Semi-Prep Semi-Prep (2/pkg) Guard Cartridges (x2) (2/pkg) Guard Cartridges (x2) (2/pkg) Guard Cartridges (x2) 50
5 ACCESSORIES FOR COLUMNS Reference Product Name Particle Size Product Type GUARD CARTRIDGE HOLDER \ Holder for guard cartridge CG000D1 GUARD COLUMN COUPLER (4 mm) I.D. \ Coupler CG000D2 GUARD COLUMN COUPLER MICRO (3 mm, 2 mm) I.D. \ Coupler 51
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