Voluntary Regulation Concerning Printing Inks. (Negative List Regulations)

Transcription

1 Voluntary Regulation Concerning Printing Inks (Negative List Regulations) May 1, 2006 Japan Printing Ink Makers Association 1

2 Introduction The Japan Printing Ink Makers Association has formulated new Voluntary Regulations Concerning Printing Inks (Negative List ( NL ) Regulations). In order to enhance the safety of printing inks and provide safer printed matter, the new regulations prohibit the use of chemical substances that are not suitable as raw materials for printing ink and it was decided to differentiate products that do not contain regulated chemical substances by applying an NL Regulation Compliant Symbol, etc., to NL Regulation compliant products. Chemical substances to be prohibited were selected based on domestic and foreign laws and information regarding substance toxicity. The regulations list all chemical substances that were prohibited for use under the previous regulations, the Voluntary Regulation Concerning Printing Inks for Food Packaging Materials (former NL Regulations). The Voluntary Regulations Concerning Printing Inks were first formulated on April 1, 1973, as the Voluntary Regulation Concerning Printing Inks For Food Packaging Materials (former NL Regulations) based on guidance of the former Ministry of Health and Welfare with the aim of ensuring the safety of printing ink for food packing materials and preventing problems. The regulations, which went into effect on October 1 of that year and went through its third amendment in 1999, prohibit the use of 130 substances including new additions in The Association member companies supply printing ink for food packaging use that complies with the former NL regulations and have contributed to improvements in food hygiene involving food product containers and packaging. In order to promote improvements in the safety and hygiene of printing inks overall while reducing the burden on the environment, efforts have been made since 2002 to disseminate products that comply with the NL Regulations by appending an NL Regulation Compliant Symbol established in that year to printing inks other than those for food packaging materials as well stating to the effect that they are in compliance with the NL Regulations. Selection standards of newly prohibited substances have been incorporated in the regulations. The standards prohibit the use of those substances whose production or usage is restricted by law as substances that are detrimental to health and the environment, carcinogens and other substances. In addition, the Marketing and Use Directive 76/769/EEC, the Packaging and Packaging Waste Directive 94/62/EC, Directive 2002/95/EC (RoHS) and the Joint Industry Guide ( JIG, Joint Industry Guide for Material Composition Declaration for Electronic Products) and other regulations were also taken into account. The Association member companies take active steps to append the NL Regulation compliant symbol to ink products that are in compliance with the NL Regulations and are seeking to upgrade safety and hygiene and reduce the burden on the environment through the dissemination of NL compliant products. 2

3 Chapter 1 Voluntary Regulations Concerning Printing Inks (Negative List (NL) Regulations) 1.1. Intent The purpose of the Voluntary Regulations Concerning Printing Inks (hereinafter referred to as the NL Regulations ) is to provide safer printing inks taking the impact on human safety and health and the environment into account. Therefore, materials that are not considered to be desirable for use as the raw materials of printing ink are selected and their use is prohibited Scope of application The NL Regulations shall apply to printing inks and related products manufactured and marketed by Association member companies. 1.3 Definitions (1) Printing ink and related products shall mean printing inks, varnishes, anchor agents, coatings, reducers and printing ink finishing, auxiliary agents (supplementary agents), etc. In addition, printing ink auxiliary agents shall mean those auxiliary agents that are added when printing for the purpose of improving the printability, film properties, etc. Cleaners, fountain solutions and other printing materials are not included in printing ink auxiliary agents. (2) Prohibited substances shall mean substances that are prohibited from intentional use as raw materials for printing ink or related products. (3) Intentional use shall mean inclusion as formulation components of printing ink or related products. 3

4 1.4. Standards for the selection of substances subject to NL Regulations Standards for the selection of regulated substances are established based on laws and ordinances in Japan and overseas and chemical substance toxicity data, and prohibited chemical substances are selected based on those standards. Note: Laws and ordinances as noted by abbreviated names and the formal names are noted under Remarks 1. Selection standard 1: The use of the substances stipulated by the laws and ordinances below and carcinogens is to be prohibited. (1) Chemical Substances Control Law Class 1 specified chemical substances Class 2 specified chemical substances (2) Industrial Safety and Health Law Manufacturing-prohibited substances (3) Industrial Safety and Health Law, Ordinance on Specified chemical substances Specified Chemical Substances Group 1 substances Group 2 substances (substances under specified supervision) (4) Industrial Safety and Health Law, Ordinance on Organic Type 1 organic solvents Solvent Poisoning (5) Industrial Safety and Health Law, Ordinance on Lead Lead compounds Poisoning (6) Toxic and Deleterious Substances Control Law Toxic substances (7) Carcinogens 1) Substances classified as carcinogenic to humans by the IARC (International Agency for Research on Cancer), European Union, or Japan Society for Occupational Health IARC: Group 1 EU: Category 1 Japan Society for Occupational Health: Group 1 2) Substances classified as strongly suspected of being carcinogenic to humans by at least two of the above three institutions IARC: Group 2A EU: Category 2 Japan Society for Occupational Health: Group 2 (Remarks 2) Note: Carcinogens contained in special work environments such as aluminum smelting or living environments, radiation or solar light, radioactive substances, lifestyle habits such as smoking, foods (special Chinese-style salted and dried fish), viruses, pharmaceuticals, human hormones, substances that are gaseous at room temperature, etc., are not included on the list. 4

5 (8) Other laws and ordinances 1) Ozone Layer Protection Law: Specific substances (ozone depleting substances) 2) Dioxins Law: Dioxins 3) Chemical Weapons Prohibition Law: Toxic substances 4) Stockholm Convention (POPs Convention): Persistent organic pollutants 5) Rotterdam Convention (PIC Convention): Substances subject to the PIC Convention 6) Radiation Hazards Prevention Law: Radioactive substances (74 Bq/b or more) Selection standard 2: The use of regulated substances selected from among those stipulated by the laws and ordinances below and toxic chemical substances is to be prohibited. (1) Laws and ordinances overseas 1) Dangerous Substances Directive (67/548/EEC) and amendments Reprotoxic substances (risk phrases R60/R61) Sensitizing substances (risk phrases R42/R43) (Remarks 3) 2) Marketing and Use Directive (76/769/EEC) and amendments 91/338/EEC 99/51/EC Cadmium and compounds 97/10/EC 99/43/EC Hexavalent chromium compounds 89/677/EEC 97/56/EC Lead and compounds 89/677/EEC Mercury and compounds 83/264/EEC Polybrominated biphenyls (PBBs) 2003/11/EC Polybrominated diphenyl ethers (PBDEs) 85/467/EEC 89/677/EEC Polychlorinated biphenyls (PCBs) 2002/45/EC Short-chained chlorinated paraffin (carbon chain length 10-13) 91/659/EEC 99/77/EC Asbestos 2003/3/EC Specified azo dyes 96/55/EC Ozone depleting substances 3) RoHS Directive (2002/95/EC) WEEE Directive (2002/96/EC) Specified heavy metals (cadmium, hexavalent chromium, lead, mercury) and compounds Polybrominated biphenyls (PBB) Polybrominated diphenyl ethers (PBDE) 4) German Regulations on Daily Necessities Specified azo dyes 5) Packaging and Packaging Waste Directive (94/62/EC) 5

6 U.S. Model Toxics in Packaging Legislation (state law) ELV Directive (2000/53/EC) and amendments Specified heavy metals (cadmium, hexavalent chromium, lead, mercury) and compounds (2) Industrial Safety and Health Law Chemical compounds recognized mutagenicity (3) Industrial Safety and Health Law, Ordinance on Specified Chemical Substances Group 2 substances (excluding substances under specified supervision) (4) Industrial Safety and Health Law, Workplace Environment Assessment Standards Substances with a standard control concentration of 5ppm or less (5) Workplace environment allowable concentrations Allowable concentrations (Japan Society for Occupational Health): substances with a concentration of 5 ppm or less Allowable concentrations (TLV-TWA) (ACGIH): substances with a concentration of 5 ppm or less (6) Carcinogens Substances classified in the following categories as carcinogenic by the IARC (International Agency for Research on Cancer), European Union, or Japan Society for Occupational Health IARC: Group 2A, 2B EU: Category 2 Japan Society for Occupational Health: Group 2, A or B (7) Acutely toxic substances: Substances corresponding to the following criteria Oral LD 50 : 300 mg/kg or less Dermal LD 50 : 100 mg/kg or less Inhalation LC 50 (gas): 500 ppm (4hr) or less (vapor): 2.0 mg/l (4hr) or less (dust): 0.5 mg/l (4hr) or less Selection standard 3: The use of substances that are judged by the Japan Printing Ink Makers Association to be undesirable for use as the raw materials of printing ink, though not applicable to either selection standard 1 nor 2, is to be prohibited. The regulated substances selected based on selection standards 1-3 are noted in Table 1: Negative List 6

7 < Remarks 1 > Abbreviations and formal names of relevant laws (1) Domestic laws and regulations Abbreviation Formal Name Industrial Safety and Health Law Industrial Safety and Health Law Chemical Weapons Prohibition Law Chemical Substances Control Law Ordinance on Specified Chemical Substances Radiation Hazards Prevention Law Ordinance on Lead Poisoning Ordinance on Organic Solvent Poisoning Ozone Layer Protection Law Stockholm Convention (POPs Convention) Dioxins Law Rotterdam Convention (PIC Convention) Law on the Prohibition of Chemical Weapons and Control of Specific Substances Law Concerning Screening of Chemical Substances and Regulation of Their Manufacture Ordinance on Prevention of Hazards due to Specified Chemical Substances Law Concerning Prevention from Radiation Hazards due to Radio-Isotopes, etc. Ordinance on Prevention of Lead Poisoning Ordinance on Prevention of Organic Solvents Poisoning Law Concerning the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures Stockholm Convention on Persistent Organic Pollutants Law Concerning Special Measures against Dioxins Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (2) EU laws and regulations Abbreviation Dangerous Substances Directive (67/548/EEC) Marketing and Use Directive (76/769/EEC) Packaging and Packaging Waste Directive (94/62/EC) Formal Name Council Directive 67/548/EEC of June 27, 1967 on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labeling of dangerous substances Council Directive 76/769/EEC of July 27, 1976 on the approximation of laws, regulations and administrative provisions of member nations relating to restrictions on the marketing and use of certain dangerous substances and preparations Directive 94/62/EC of the European Parliament and the Council of 20 December 1994 on packaging and packaging 7

8 ELV Directive (94/62/EC) RoHS Directive (2002/95/EC) WEEE Directive (2002/96/EC) waste Directive 2000/53/EC of the European Parliament and of the Council of 18 September 2000 on end-of-life Vehicles Directive 2002/95/EC of the European Parliament and of the Council of 27 January 2003 on the restriction of the use of certain hazardous substances in electrical and electronic equipment (RoHS) Directive 2002/96/EC of the European and of the Council of 27 Jan 2003 on waste electrical and electronic equipment (WEEE) <Remarks 2 > Classification of carcinogens IARC Group 1: Substances carcinogenic to humans Group 2A: Substances probably carcinogenic to humans Group 2B: Substances possibly carcinogenic to humans Group 3: Substances that cannot be classified as carcinogenic to humans Group 4: Substances probably not carcinogenic to humans EU Category 1: Substances known to be carcinogenic to humans Category 2: Substances recognized to be carcinogenic to humans Category 3: Substances that arouse concern about effects on humans since there may be a carcinogenic effect; however, information regarding usability is inadequate for making an assessment Japan Society for Occupational Health Group 1: Substances carcinogenic to humans Group 2: Substances thought to be probably carcinogenic to humans Group 2A: Substances with more evidence Group 2B: Risk of sensitization by contact with the skin <Remarks 3> (EU) Risk phrases Reprotoxicity R60: Substances that may impair fertility R61: Substances that may cause harm to the unborn child Sensitization R42: Substances that may cause sensitization upon inhalation R43: Substances that may cause sensitization upon contact with the skin 8

9 <References> 1. Japan Chemical Industry Ecology-Toxicology & Information Center (JETOC), Special material No.180, EU Council Directive 76/769/EEC relating to the restrictions on the marketing and use of certain dangerous substances and preparations, 5th edition (November 2003) 2. Japan Chemical Industry Ecology-Toxicology & Information Center (JETOC), Special material No.190, Assessment of the carcinogenicity of chemical substances and classification standards, 6th edition (September 2004) 3. Japan Chemical Industry Association, Green Procurement compatible system material (revised) ( 4. Japan Green Procurement Survey Standardization Initiative, Practical Application of Green Procurement (February 2004) 5. Joint Industry Guide for Material Composition Declaration for Electronic Products (JIG), No.JIG-101 (Japanese translations) (July 15, 2005) 6. Office for Official Publications of the EC, Council Directive of 27 July 1976 on the approximation of the laws, regulations and administrative provisions of the Member States relating to restrictions on the marketing and use of certain dangerous substances and preparations CONSLEG: 1976L /03/2004 9

10 1.5. Formulation and enforcement Voluntary Regulations Concerning Printing Inks (NL Regulations) Formulation date: May 1, 2006 Effective date: November 1, 2006 (Remarks) Voluntary Regulation Concerning Printing Inks For Food Packaging Materials (former NL Regulations) Formulation date: April 1, 1973 Effective date: October 1, st amendment date: April 1, 1977 Effective date (solvents, auxiliary agents): October 1, 1977 Effective date (coloring agents): April 1, nd amendment date: April 1, 1993 Effective date: October 1, rd amendment date: April 30, 1999 Effective date: August 1, 1999 Invalidation date: November 1, Implementation outline Labels Products manufactured in compliance with the NL Regulations shall in principle bear the NL Regulation compliant symbol ( NL Mark ) or the following label on each container. This product has been manufactured in compliance with the Voluntary Regulations Concerning Printing Inks (NL Regulations) of the Japan Printing Ink Makers Association. The NL Regulation compliant symbol indicates that the product was manufactured in compliance with the NL Regulations. It was established in December (pasting trademark NL mark ) Japan Printing Ink Makers Association 10

11 Certificate issuance Association member companies may, at their own responsibility, issue certificates in response to requests from customers, etc., certifying that the product in question was manufactured in compliance with the NL Regulations. The certificate form is presented in <Appendix 2> (A4 size). <Appendix 2> To: Date: (company name) (Seal) RE: Products supplied by our company We would like to take this opportunity to offer our best wishes for your continued prosperity and to thank you for your constant patronage. We would like to advise you regarding the matter captioned above as indicated below and ask for your kind consideration upon your confirmation. 1. Our product(s): 2. Content: The above product(s) was (were) manufactured in compliance with the Voluntary Regulations Concerning Printing Inks (NL regulations) (formulated May 2006) of the Japan Printing Ink Makers Association. Japan Printing Ink Makers Association form #1, 5/ Obligation to comply with NL Regulations Association member companies shall comply with these Voluntary Regulations according to their own sound judgment. In the event that problems arise in products manufactured in compliance with the NL Regulations, they shall resolve such problems at their own responsibility. 11

12 Amendments of the NL Regulations The NL Regulations shall be amended as required in the event of the amendment of laws and/or ordinances, upon confirmation of new toxicity or safety, etc. 12

13 Table-1: Negative List Excluded Substances based on selection standard 1 No. Substance CAS No. Former NL Chemical Substances Control Law/Class 1 Specified Chemical Substances 1 Polychlorinated biphenyls (PCB) Polychlorinated naphthalenes (substances with three or more chlorine atoms only) 3 Hexachlorobenzene ,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-exo-1,4-endo-5,8- dimethanonaphthalene (also known as Aldrin) ,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-exo- 1,4-endo-5,8-dimethanonaphthalene (also known as Dieldrin) ,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydroendo-1,4-endo-5,8-dimethanonaphthalene (also known as Endrin) ,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (also known as DDT) Mixture of 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7- methano-1h-indene, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro- 4,7-methano-1H-indene, and their analogs (also known as Chlordane 9 Bis (tributyltin)=oxide (also known as Distannoxane) N,N'-ditolyl-p-phenylenediamine, N-tolyl-N'-xylyl-p-phenylenediamine and N,N'-dixylyl-p-phenylenediamine ,4,6-Tri-tert-butylphenol Polychloro-2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane (also known as Toxaphene) Dodecachloropentacyclo[ ,60.3,90.4,8]decane (also known as ,2,2-Ttrichloro-1,1-bis (4-chlorophenyl) ethanol(also known as Kelthane or Dicofol) Hexachlorobuta-1, 3-diene Chemical Substances Control Law/Class 2 Specified Chemical Substances 16 Trichloroethylene Tetrachloroethylene Carbon tetrachloride Triphenyltin=N,N-Dimethyldithiocarbamate Triphenyltin=Fluoride Triphenyltin=Acetate Triphenyltin=Chloride Triphenyltin=Hydroxide Triphenyltin=fatty acid salts(only those containing 9,10 or 11 carbon atoms in the fatty acid) 25 Triphenyltin=Chloroacetate Tributyltin=Methacrylate Bis (tributyltin)=fumarate 28 Tributyltin=Fluoride 29 Bis(tributyltin)=2,3-Dibromosuccinate Tributyltin=Acetate Tributyltin=Laurate Bis(tributyltin)=Phthalate Alkyl=acrylate, methyl=methacrylate and tributyltin=copolymer of methacrylate (alkyl=for alkyl group of acrylate with eight carbon atoms) Tributyltin=Sulfamate Bis(tributyltin) maleate Tributyltin chloride Tributyltin=mixture of cyclopentanecarboxylate and its analogs (also known as Tributyltin naphthenate) 38 Tributyltin=mixture of 1,2,3,4,4a,4b,5,6,10,10a-decahydro-7-isopropyl- 1,4a-dimethyl-1-phenanthlenecarboxylate and its analogs (also known as tributyltin rosin salt) Industrial Safety and Health Law / Manufacturing-prohibited substances 39 Yellow phosphorus matches Benzidine and its salts 41 4-Aminodiphenyl and its salts 42 Amosite Crocidolite Nitrodiphenol and its salts 45 Bis (chloromethyl) ether

14 No. Substance CAS No. Former NL 46 β-naphthylamine and its salts 47 Asbestos (exclusive of amosite and crocidolite) Gum containing benzene in a quantitative amount of more than 5% by volume of the solvent (including dilutants) of the saidgum Industrial Safety and Health Law, Ordinance on Specified Chemical Substances / Specified Chemical Substances, Group-1 substances 49 Dichlorobendizine and its salts 50 α-naphthylamine and its salts 51 Chlorinated biphenyl (otherwise known as P.C.B.) o-tolidine and its salts 53 Dianisidine and its salts 54 Beryllium and its compounds 55 Benzotrichloride Industrial Safety and Health Law, Ordinance on Specified Chemical Substances / Specified Chemical Substances, Group-2 substances(substances under specified supervion) 56 Ethyleneimine Ethylene oxide Vinyl chloride Auramine Chromic acid and its salts 61 Chloromethyl methyl ether Coal tar Arsenic trioxide ,3'-Dichloro-4,4'-diaminodiphenylmethane Dichromic acid and its salts 66 Nickel carbonyl p-dimethylaminoazobenzene β-propiolactone Benzene Magenta Industrial Safety and Health Law, Ordinance on Organic Solvent Poisoning /Type 1 organic 71 Chloroform Carbon tetrachloride ,2-Dichloroethane (otherwise known as ethylene dichloride) ,2-Dichloroethylene (otherwise known as acetylene dichloride) ,1,2,2-Tetrachloroethane (otherwise known as acethylene Trichloroethylene Carbon disulfide Industrial Safety and Health Law, Ordinance on Lead Poisoning / Lead compounds 78 Lead oxide Lead hydroxide Lead chloride Lead carbonate Lead silicate Lead sulfate Lead chromate Lead titanate Lead borate Lead arsenate Lead nitrate Lead acetate Lead stearate Poisonous and Deleterious Subsutances Control Law/Poisonous Substances 91 Ethylparanitrophenylthiono benzenephosphonate Yellow phosphorus Octachlorotetrahydro methanophthalan Octamethyl- pyrophosphoramide Curare Tetraalkyl lead 97 Hydrogen cyanide Sodium cyanide Diethyl-paranitrophenyl-thiophosphate Dinitro-o-cresol

15 No. Substance CAS No. Former NL 101 2,4-Dinitro-6-(1-methylpropyl)-phenol O, O-dimethyl-O-ethylmercaptoethyl thiophosphate Dimethyl-(diethylamido-1-chlorocrotonyl)-phosphate Dimethylparanitrophenyl thiophosphate Mercury Selenium Thiosemicarbazide Tetraethylpyrophosphate Nicotine Nickel carbonyl Arsenic Hydrofluoric acid Hexachloro-epoxy-octahydro-endo,endo-dimethanonaphthalene Hexachloro-hexahydro-methano-benzo-dioxathiepine oxide Monofluoroacetate Fluoroacetamide Phosphorus pentasulfide Sodium azide Amino-1-propen Allyl alcohol ,4-Dinitro-6-(1-methylpropyl)-phenol O-Ethyl-O-(2- isopropoxycarbonylphenyl)- N O-Ethyl S,S-dipropyl phosphorodithioate Phosphorus oxychloride Chloroacetaldehyde Phosphorus pentachloride Titanium trichloride ー Boron trichloride Phosphorus trichloride Boron trifluoride Phosphorous trifluoride Diacetoxypropene Inorganic cyanide compounds (exclusive of Berlin blue, ferricyanide salts and ferrocyanide salts) 134 Diethyl-S-(ethylthioethyl)-dithiophosphate Diethyl-S-(2-chloro-1-phthalimidoethyl)-dithiophosphate Diethyl-(1,3- dithiocyclopentylidene)-thiophosphoramide Diethyl-p-dimethylamino sulfonylphenylthiophosphate 138 Diethyl-4-methylsulfinylphenyl-thiophosphate Dinitrocresol salts Diphenylacetyl-1,3-indandione Sulfur tetrafluoride Diborane Dimethyl-(isopropylthioethyl)-dithiophosphate ,1'-Dimethyl-4,4'-dipyrdinium hydroxide and its salts 145 2,2-Dimethyl-1,3-benzodioxol-4-yl-N-methylcarbamate Mercury compounds (exclusive of mercuric amidechloride, mercurous chloride, mercury olate, mercuric oxide, mercurous iodide, mercuric 147 difulminate and mercuric sulphide) Strychnine and its salts 148 Selenium compounds 149 2,3,5,6-Tetrafluoro-4-methylbenzyl (Z)-(1RS,3RS)-3-(2-chloro-3,3,3- trifluoro-1-propenyl-2,2-dimethylcyclopropanecarboxylate Narasin Nicotine salts 152 S,S-bis(1-methylpropyl) O-ethyl phosphorodithioate Arsenic compounds(exclusive of indium arsenide, gallium arsenide, calcium methane arsonate and iron methane arsonate) 154 Hydrazine Butyl 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N,N'-dimethyl-N,N'- thiodicarbamate Sulfuryl fluoride Fluorosulfonic acid Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidyl]-2-oxopropyl]- 4(3H)-quinazolinone

16 No. Substance CAS No. Former NL 159 Hexachlorocyclopentadiene Benzenethiol Phosgene Methylcyclohexyl-4-chlorophenylthiophosphate Methyl-N',N'-dimethyl-N- [(methylcarbamoyl)oxy]-1-thiooxamimidate Methylphosphonic acid dichloride Methyl mercaptan Methylenebis(1-thiosemicarbazide) Monofluoroacetates 168 Aluminium phosphide Hydrogen phosphide Tungsten hexafluoride Carcinogen No. Class of carcinogenicity EU IARC JSOH Substance CAS No Former NL Azathioprine Asbestos Aflatoxins (naturally occurring mixtures of) Aminobiphenyl Salts of 4-aminobiphenyl, Salts of biphenyl- 4-ylamine, Ssalts of xenylamine Ethylene oxide Erionite Erionite Vinyl chloride Cadmium and cadmium compounds Zinc chromates including zinc potassium (2-Chloroethyl)-3-(4-methylcyclohexyl)-1- nitrosourea (Methyl-CCNU; Semustine) Chlormethyl methyl ether, Chlorodimethyl Coal oil, Tar, coal, low-temp Coal tar, Tar, coal, high-temp Coal-tar pitches Coal-tars Arsenic oxide, Arsenic pentoxide, Diarsenic pentaoxide Chromium (VI) trioxide Arsenic trioxide, diarsenic trioxide Shale-oils Diethylstilboestrol Ciclosporin Cyclophosphamide Cyclophosphamide Soots Silica crystalline (inhaled in the form of quartzor cristobalite from occupational Tamoxifen Thiotepa ,3,7,8-Tetrachlorodibenzo-para-dioxin Triethyl arsenate Treosulfan Naphthylamine Salts of 2-naphthylamine Nickel compounds Gallium arsenide Arsenic acid and its salts Lead hydrogen arsenate Chlorambucil Mustard gas (Sulfur mustard) N,N-Bis(2-chloroethyl)-2-naphthylamine

17 No. Substance CAS No. Former NL Bis(chloromethyl)ether and chloromethyl methyl ether Arsenic and arsenic compounds ,4-Butanediol dimethanesulfonate Tar brown-coal Tar, brown-coal, low-temp Beryllium and beryllium compounds Benzidine Salts of benzidine Benzene Formaldehyde Mineral oils, untreated and mildly treated Methoxypsoralen (Methoxsalen) plus ultraviolet A radiation Melphalan Distillates (petroleum), chemically neutralized light naphthenic, Unrefined or mildly refined Distillates (petroleum), chemically neutralized light paraffinic, Unrefined or mildly refined Distillates (petroleum), chemically neutralized heavy naphthenic, Unrefined or mildly refined baseoil Distillates (petroleum), chemically neutralized heavy paraffinic, Unrefined or mildly refined Distillates (petroleum), light naphthenic, Unrefined or mildly refined baseoil Distillates (petroleum), light paraffinic, Unrefined or mildly refined baseoil Distillates (petroleum), acid-treated light paraffinic, Unrefined or mildly refined baseoil Distillates (petroleum), acid-treated light naphthenic, Unrefined or mildly refined Distillates (petroleum), acid-treated heavy naphthenic, Unrefined or mildly refined Distillates (petroleum), acid-treated heavy paraffinic, Unrefined or mildly refined baseoil Distillates (petroleum), heavy naphthenic, Unrefined or mildly refined baseoil Distillates (petroleum), heavy paraffinic, Unrefined or mildly refined baseoil Phosphorus-32, as phosphate Chromium[VI] compounds Certain Chromium[VI] compounds A 2A Acrylamide, Prop-2-enamide A Acrylonitrile A 1-Chloro-2,3-epoxypropane, Epichlorhydrin A (Epoxyethyl)benzene, Phenyloxirane, Styrene oxide A 2,3-Epoxypropan-1-ol, Glycidol, A Dimethylcarbamoyl chloride A Creosote, [The distillate of coal tar produced A 4-Chloro-o -toluidine [1] [1] A 2A 2,2'-Dichloro-4,4'-methylenedianiline, 4,4' A Dibenz[a,h]anthracene A 1,2-Dimethylhydrazine A Bromoethylene A 1,2-Dibromoethane A 1,2,3,6-Tetrahydro-N-(1,1,2,2- tetrachloroethylthio)phthalimide, Captafol A Trichloroethene, Trichloroethylene A 1,2,3-trichloropropane A o -Toluidine, 2-Aminotoluene A N -Nitrosodimethylamine, A Benzotrichloride, α,α,α-trichlorotoluene

18 No. Substance CAS No. Former NL A Benzyl chloride, α-chlorotoluene A Benz[a]anthracene A Benzo[a]pyrene, Benzo[def]chrysene A 1-Methyl-3-nitro-1-nitrosoguanidine A Diethylsulphate A 2A Dimethylsulphate No. Substance CAS No. Foprmer Ozone Layer Control Law/Specified Substances(ozon depleting Substances) The Montreal Protocol/Annex A: Controlled Substances Group Trichlorofluoromethane(CFC-11) Dichlorodifluoromethane(CFC-12) Trichlorotrifluoroethane(CFC-113) 268 Dichloro tetrafluoroethane(cfc-114) 269 Chloropentafluoroethane(CFC-115) The Montreal Protocol/Annex A: Controlled Substances Group Bromochlorodifluoromethane(Halon-1211) Bromotrifluoromethane(Halon-1301) Dibromotetrafluoroethane(Halon-2402) The Montreal Protocol/Annex B: Controlled Substances Group Chlorotrifluoromethane(CFC-13) Pentachlorofluoroethane(CFC-111) Tetrachlorodifluoroethane(CFC-112) 276 Heptachlorofluoropropane(CFC-211) 277 Hexachlorodifluoropropane(CFC-212) 278 Pentachlorotrifluoropropane(CFC-213) 279 Tetrachlorotetrafluoropropane(CFC-214) 280 Trichloropentafluoropropane(CFC-215) 281 Dichlorohexafluoropropane(CFC-216) 282 Chloroheptafluoropropane(CFC-217) 283 The Montreal Protocol/Annex B: Controlled Substances Group 2 Tetrachloromethane The Montreal Protocol/Annex B: Controlled Substances Group 3 Methylchloroform The Montreal Protocol/Annex C: Controlled Substances Group 1 Dichlorofluoromethane(HCFC-21) Chlorodifluoromethane(HCFC-22) Chlorofluoromethane(HCFC-31) Tetrachlorofluoroethane(HCFC-121) 289 Trichlorodifluoroethane(HCFC-122) 290 Dichlorotrifluoroethane(HCFC-123) 291 Chlorotetrafluoroethane(HCFC-124) 292 Trichlorofluoroethane((HCFC-131) 293 Dichlorodifluoroethane(HCFC-132) 294 Chlorotrifluoroethane(HCFC-133) 295 Dichlorofluoroethane(HCFC-141) 297 Chlorodifluoroethane(HCFC-142) 299 Chlorofluoroethane(HCFC-151) 300 Hexachlorofluoropropane(HCFC-221) 301 Pentachlorodifluoropropane(HCFC-222) 302 Tetrachlorotrifluoropropane(HCFC-223) 303 Trichlorotetrafluoropropane(HCFC-224) 304 Dichloropentafluoropropane(HCFC-225) 305 Chlorohexafluoropropane(HCFC-226) 306 Pentachlorofluoropropane(HCFC-231) 307 Tetrachlorodifluoropropane(HCFC-232) 308 Trichlorotrifluoropropane(HCFC-233) 309 Dichlorotetrafluoropropane(HCFC-234) 310 Chloropentafluoropropane(HCFC-235) 311 Tetrachlorofluoropropane(HCFC-241) 312 Trichlorodifluoropropane(HCFC-242) 313 Dichlorotrifluoropropane(HCFC-243) 314 Chlorotetrafluoropropane(JHCFC-244) 315 Trichlorofluoropropane(HCFC-251)

19 No. Substance CAS No. Former NL 316 Dichlorodifluoropropane(HCFC-252) 317 Chlorotrifluoropropane(HCFC-253) 318 Dichlorofluoropropane(HCFC-261) 319 Chlorodifluoropropane(HCFC-262) 320 Chlorofluoropropane(HCFC-271) The Montreal Protocol/Annex C: Controlled Substances Group Dibromofluoromethane Bromodifluoromethane(HBFC-22B1) Bromofluoromethane Tetrabromofluoroethane 325 Tribromodifluoroethane 326 Dibromotrifluoroethane 327 Bromotetrafluoroethane 328 Tribromofluoroethane 329 Dibromodifluoroethane 330 Bromotrifluoroethane 331 Dibromofluoroethane 332 Bromodifluoroethane 333 Bromofluoroethane 334 Hexabromofluoropropane 335 Pentabromodifluoropropane 336 Tetrabromotrifluoropropane 337 Tribromotetrafluoropropane 338 Dibromopentafluoropropane 339 Bromohexafluoropropane 340 Pentabromofluoropropane 341 Tetrabromodifluoropropane 342 Tribromotrifluoropropane 343 Dibromotetrafluoropropane 344 Bromopentafluoropropane 345 Tetrabromofluoropropane 346 Tribromodifluoropropane 347 Dibromotrifluoropropane 348 Bromotetrafluoropropane 349 Tribromofluoropropane 350 Dibromodifluoropropane 351 Bromotrifluoropropane 352 Dibromofluoropropane 353 Bromodifluoropropane 354 Bromofluoropropane The Montreal Protocol on Substances that Deplete the Ozone Layer/Annex C: Controlled 355 Bromochloromethane The Montreal Protocol on Substances that Deplete the Ozone Layer/Annex E: Controlled 356 Bromomethane Dioxins Law 357 Polychlorinated dibenzofurans 358 Polychlorodibenzo-para-dioxins 359 Co-planar polychlorinated biphenyls Chemical Weapons Prohibition Law Enforcement order /Attached Table Specific Chemicals (Toxic Chemicals) 360 O-Alkyl (<C10, incl. cycloalkyl) alkyl(me, Et, n-pr or i-pr)- phosphonofluoridates 361 O-Alkyl (<C10, incl. cycloalkyl) N,N-dialkyl(Me, Et, n-pr or i-pr) 362 O-Alkyl (<C10, incl. cycloalkyl) S-2-dialkyl(Me, Et, n-pr or i-pr)- 363 S-2-dialkyl(Me, Et, n-pr or i-pr)-aminoethyl alkyl(me, Et, n-pr or i-pr) Chloroethylchloromethylsulfide Mustard gas: Bis(2-chloroethyl)sulfide Bis(2-chloroethylthio)methane Sesquimustard: 1,2-Bis(2-chloroethylthio)ethane ,3-Bis(2-chloroethylthio)-n-propane ,4-Bis(2-chloroethylthio)-n-butane ,5-Bis(2-chloroethylthio)-n-pentane Bis(2-chloroethylthiomethyl)ether O-Mustard: Bis(2-chloroethylthioethyl)ether

20 No. Substance CAS No. Former NL 373 Lewisite 1: 2-Chlorovinyldichloroarsine Lewisite 2: Bis(2-chlorovinyl)chloroarsine Lewisite 3: Tris(2-chlorovinyl)arsine HN1: Bis(2-chloroethyl)ethylamine HN2: Bis(2-chloroethyl)methylamine HN3: Tris(2-chloroethyl)amine Saxitoxin Ricin Enforcement order /Attached Table First Class Chemicals (Toxic Chemicals) 381 Amiton: O,O-Diethyl S-[2-(diethylamino)ethyl]phosphorothiolate and corresponding alkylated or protonated salts PFIB: 1,1,3,3,3-Pentafluoro-2-(trifluoromethyl)-1-propene BZ: 3-Quinuclidinyl benzilate Enforcement order /Attached Table Secod Class Chemicals (Toxic Chemicals) 384 Phosgene: Carbonyl dichloride Cyanogen chloride Hydrogen cyanide Chloropicrin: Trichloronitromethane Stockholm Convention(POP Convention)/Persistent Organic Pollutants (POPs) 388 Aldrin Dieldrin Endrin Hexachlorobenzene (HCB) Chlordane Heptachlor Toxaphene Mirex Polychlorinated biphenyls (PCB) 397 1,1,1Trichloro-2,2-bis(4-chlorophenyl)ethane(DDT) Polychlorinated dibenzo-p-dioxins (PCDD) 399 Polychlorinated dibenzofurans (PCDF) 400 Polychlorinated biphenyls (PCB) 401 Hexachlorobenzene (HCB) Rotterdam Convention(PIC Convention)/Substances subject to the Pic Convention T and its salts and esters 403 Aldrin Binapacryl Captafol Chlordane Chrordimeform Chlorobenzilate DDT Dieldrin Dinitro-ortho-cresol(DNOC)and its salts (such as ammonium salt, potassium salt and sodium salt) 412 Dinoseb and its salts and esters dibromoethane(EDB) dichroloethane Ethylene oxide Fluoroacetamide HCH(mixed isomers) Heptachlor Hexachlorobenzene Lindane Mercury compounds(including inorganic mercury compounds, alkyl mercury compounds and alkyloxyalkyl and aryl mercury compounds) 422 Monocrotopophos Prathion Pentachlorophenol and its salts and esters 425 Toxaphene Benomyl Carbofuran Thiram Methamidophos

21 No. Substance CAS No. Former NL 430 Phosphamidon Methyl-parathion Asbestos 433 Polybrominated biphenyls(pbb) 434 Polychlorinated biphenyls(pcb) 435 Polychlorinated terphenyls(pct) 436 Tetraethyl lead Tetramethyl lead Tris(2,3-dibromopropyl)phosphate Radiation Hazards Prevention Law The compounds which have a nuclide mentioned in table -1 according 439 to the fifth Science and Technology Agency notification "Matter to Determine Amount of an Isotope Discharging Radioactive Rays"

22 Excluded Substances based on selection standard 2 No. Substance CAS No. Former NL Marketing and use directive(76/769/eec) The directive revision 89/677/EEC, 97/56/EEC / Lead and lead compounds 440 Lead and lead compounds Marketing and use directive(76/769/eec) 83/264/EEC: Polybrominated biphenyls 2003/11/EC: Polybrominated diphenyl ethers 2002/95/EC: RoHS Directive 441 Polybrominated biphenyls 442 Polybrominated diphenyl ethers The directive relating to restriction on the marketing and use 76/769/EEC The 20th revison 2002/45/EC : Short chain length chlorinated paraffins 443 Short chain length chlorinated paraffins (C=10~13) Marketing and use directive(76/769/eec) 2003/3/EC: Specified azo pigment German Regulations on Daily Necessities Specified amine aromatic amines Aminodiphenyl Benzidine Chloro-o-toluidine Naphthylamine o-aminoazotoluene Nitro-o-toluidine Chloroaniline Methoxy-m-phenylenediamine ,4'-Methylenedianiline ,3'-Dichlorobenzidine ,3'-Dimethoxybenzidine ,3'-Dimetylbennzidine ,4'Methylenedi-o-toluidine Methoxy-m-toluidine ,4'-Methylene-bis-(2-chloraniline) ,4'-Oxydianiline ,4'-Thiodianiline o-toluidine Methyl-1,3-phenylenediamine ,4,5-Trimethylaniline o-anisidine Aminoazobenzene The azo dye which generates specification amine The azo pigment which generates specification amine/an evaluation classification [B] on ETAD 467 C.I. Pigment Red C.I. Pigment Red C.I. Pigment Red Industrial Safety and Health Law/Chemical compounds recognized mutagenicity Hydroxyethyl acrylate Phenol, 4,4'-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane (Bisphenol A type epoxy liquid resins) Methylene chloride Phenol, methylene bis-, polymer with (chloromethyl)oxirane (Methylene bisphenol type epoxy liquid resins) Industrial Safety and Health Law, the Ordinance on Specified Chemical Substances/Group-2 substances 474 Toluene diisocyanates Workplace environment allowable concentrations Alloowable concentrations(jsoh): substances with a concentration of 5ppm or less Alloowable concentrations(tlv-twa)(acgih): substances with a concentration of 5ppm or Ethoxyethanol, Ethyleneglycolmonoethylether Ethoxyethyl acetate, Ethyleneglycolmonoethyletheracetate Methoxyethanol, Ethyleneglycolmonomethylether Methoxyethyl acetate, Ethyleneglycolmonomethyletheracetate

23 No. Substance CAS No. Former NL Carcinogens 479 Ethyl acrylate N,N-Dimethylformamide Nitropropane Ponceau 3R Acute toxic substances 483 Isophorone diisocyanate Glycidyl acrylate Crystal violet Cobalt compounds (Water soluble inorganic salts) 487 Diethyleneglycol diacrylate (Dimethylamino)ethyl methacrylate Methyl-1,3-phenylene=diisocyanates 490 4,4'-Bis(dimethylamino)benzophenone Hydroxypropyl acrylates 492 N-Vinyl-2-pyrolidone Hexamethylene diisocyanate Pentachlorophenol (PCP) and its salts

24 Excluded Substances based on Selection Standard 3 No. Substance CAS No. Former NL 495 Antimony white Antimony red Oil yellow OB Oil orange SS (solvent orange-2) Oil orange XO Auramine lake 501 Guinea green B (acid green-3) Chrysoidine (basic orange-2) Sudan I Ponceau SX Magenta lake 506 Mercarite 507 Barium stearete Manganese violet Dibutyltin dichloride Dibutyltin diacetate Dibutyltin dibutanate 512 Dibutyltin dipentanate 513 Diamond green G (basic green-1) Victoria blue 4R Victoria blue B Malachite green Methyl violet Chlorinated naphthalenes 519 o-dichlorebenzene Monochlorobenzene Vinyl acetate (monomer) Rhodamine 3G 523 Rhodamine 6G (basic red-1) Rhodamine B Tricresyl phosphate Monocresyl phosphate 527 Patina