1. COURSE/SUBJECT IDENTIFICATION 2. LECTURERS OF THE COURSE/SUBJECT

Transcription

1 COURSE DESCRIPTION INORGANIC CHEMISTRY YEAR 1 2ND SEMESTER DEGREE: PHARMACY MODALITY: ATTENDANCE IS REQUIRED ACADEMIC YEAR 2016/2017 FACULTY OF PHARMACY

2 1.- COURSE/SUBJECT: 1. COURSE/SUBJECT IDENTIFICATION Name: Inorganic Chemistry Code:a107 Year course is taught: First Semester when the course is taught: 2 nd Type: Compulsory subject ECTS of the course: 6 Hours ECTS: (30) Language: English Modality: on campus, attendance is required Degree in which the course is taught: Pharmacy School which the course is taught: Pharmacy 2.- ORGANIZATION OF THE COURSE: Department: Chemistry and Biochemistry Area of knowledge: Inorganic Chemistry 1.-LECTURERES: Responsible of the Course Name: 2. LECTURERS OF THE COURSE/SUBJECT CONTACT Phone (ext): Office: Teaching and Research profile Research Lines Prof. Dr. D. Flaviano García Alvarado flaga@ceu.es Vicedean s office, Building A Chair Professor Solid State Chemistry and materials (24 certified years of international quality research) Lecturer(s) CONTACT Name: Prof. Dr. D. Alois Kuhn Phone (ext): akuhn@ceu.es Office: Building C 2.- TUTORIALS: For any queries students can contact lecturers by , phone or visiting their office during the teacher s tutorial times published on the students Virtual Campus. 2

3 3. COURSE DESCRIPTION Description of the properties of metallic and non-metallic chemical elements and their compounds. Non-metallic elements and their compounds are studied by groups and their natural state and its preparation methods revised in the light of an elementary theoretical approach to facilitate the understanding of their uses. The transition metal chemistry and the formation of coordination compounds is described followed by an introduction to the bioinorganic chemistry. This is exemplified in the role of the hemoglobin, as coordination compound, in oxygen transport. 1.- COMPETENCIES 4. COMPETENCIES Code CB1 CB2 Basic and General Competencies Students have been shown to possess and understand knowledge in an area of study that is based on general secondary education at a level that, although it is supported by advanced textbooks, includes some issues of the forefront of knowledge of that field of study. Students apply their knowledge to their work or vocation in a professional manner, and have competencies that can be demonstrated through devising and defending arguments or solving problems within their field of study. Code C8 C9 C10 Specific Competencies To identify the general properties of metallic and non-metallic elements and inorganic compounds. To understand the characteristics and properties of coordination compounds in biological processes. To understand the role and importance of metals and inorganic compounds in biological processes 2.- LEARNING OUTCOMES: Code RA9 RA10 RA11 RA12 Learning outcomes Identify properties of the elements and inorganic chemicals and processes Apply bonding theories to the various inorganic compounds and collect their properties. Understanding of the functions of metals and inorganic compounds in biological process Experience the properties of inorganic compounds 3

4 5. LEARNING ACTIVITIES 1.- DISTRIBUTION OF STUDENTS` ASSIGNMENT: Total hours of the course 180 Code Name On-campus hours AF1 Lecture 1 AF2 Seminar 40 AF3 Workshop 9 AF4 Practice Laboratory Practice 24 AF6 Other 4 TOTAL Presence Hours 78 Code Name Not oncampus hours AF10 Self student work DESCRIPTION OF LEARNING ACTIVITIES: Activity AF1 Lecture Definition Learning activity oriented preferably to the competence of acquisition of knowledge (competence 1 MECES) and representative of more theoretical subjects. This activity gives priority to the transmission of knowledge by the professor, with the previous preparation or later study from the student. AF2 Seminar AF3 Workshop Learning activity which highlights the participation of the student in the reasoned interpretation of the contents and the sources of the area of study. It is oriented preferably to the competence of the application of knowledge (competence 2 MECES), and also to the ability of gathering, interpreting, and judging information and relevant data (competence 3 MECES). It is representative of mixed profile activities or subjects; theories and practices. Learning activity oriented preferably to the competence of the acquisition of abilities related to transmission of knowledge (competence 4 MECES) and representative of more methodological subjects. It prepares the student for written-oral communication and transmission of knowledge. AF4 Practice Learning activity oriented preferably to the competence of application of knowledge (competence 2 MECES) and representative of subjects or practical activities (labs, radio studies, TV studies and/or any other proper space). AF6 Exams Other 4

5 6. ASSESMENT OF LEARNING 1.- CLASS ATTENDANCE: In order to be eligible for examination by continuous assessment students must attend at least 75% of scheduled class time (attendance sheets will be used). As students may be absent 25% of the classes, no attenuating circumstances will be accepted for absences. 100% attendance at practical classes is required. (EN CASO DE CLASES PRÁCTICAS) 2.- ASSESMENT SYSTEM AND CRITERIA: ORDINARY EXAMINATION (continuous assessment) 1 Code Name Percentage S7 On-site evaluation (Classroom) 5% S3 Written exam requiring reasoned answers. Minimum mark: 4 (2) 20% S5 Written examination with exercises, problems, case studies, etc. Minimum mark: 4 S3 Written exam requiring reasoned answers. Minimum mark: 4 20%-40% S5 Written examination with exercises, problems, case studies, etc. Minimum mark: 4 15% 15%-30% S11 Practical workbook. Minimum mark: 5 5% S7 S7 On-site evaluation (Practical work). Attitude and performance during the sessions. Minimum mark: 5 On-site evaluation (Practical work). To carry out a practical work under the assessment of demonstrator. Minimum mark: 5 5% 15% RE-TAKE EXAM/EXTRAORDINARY EXAMINATION Code Name Percentage S3 Written exam requiring reasoned answers. Minimum mark: 5 40% S5 Written examination with exercises, problems, case studies, etc. Minimum mark: 5 S5 Written exam requiring reasoned answers. Laboratory. Minimum mark: 5 25%-0% 35% Ordinary exam Laboratory mark 0%-25% (1) In the exceptional case students cannot attend class, by written request to the teacher, the student may be submitted to the ordinary test where he/she will be assessed based on the competence of the subject which will be 75% of the final grade. (2) Minimum mark to be reached to apply percentages. (3) Student who do not undertake either ordinary or extraordinary exam will be marked NP, even though they have performed any other academic activity of continuous assessment. 5

6 (4) Both theoretical and practices needs to be marked with a minimum of 5 to apply to pass the subject. 3.- DESCRIPTION OF ASSESSMENT CRITERIA: Assesment criteria Definition Written exam requiring reasoned answers Written examination with exercises, problems, case studies, etc. Written exam where the student must answer questions in a very short way about some statements giving a reasoned answer or justifying the veracity of the statements Written exam where the student must solved problems making calculations, application of formulas or justifying some data. On-site evaluation Assessment of student performances in the practical sessions or in the dayto-day workshops and seminar where his/her participation is expected. Practical workbook Assessment of clarity and completeness of laboratory notebook reflecting the daily work of the student in the lab, the methodology and the results as well as calculation when required. On-site evaluation (Practical work). Taking place in the last practical session. It consists of a practical exam by means of the assignment of an individual laboratory work to the student for him to write a description of the methodology to be applied, the material to be used and to calculate the required data (mass, volume of reagents, etc.). Afterwards, the student will carry out the corresponding experimental work under the examination of the demonstrator. 7. COURSE PROGRAMME 1.- COURSE PROGRAMME: THEORETICAL: (Seminars. Masters class as indicated) I. GENERAL STUDY OF NON METALLIC ELEMENTS AND THEIR COMBINATIONS Chapter 1.- HYDROGEN AND ITS COMBINATIONS: General characteristics. Isotopes. Molecular and atomic hydrogen. Ions. Reactivity. Occurrence, production and applications. Hydrides: General characteristics. Bonding. Physical properties. Stability. Chemical properties: variation of the acid character. Chapter 2.- NOBLE GASES: General characteristics of the elements. Physical properties and chemical reactivity. Occurrence, production and applications. Chapter 3.- GROUP 17: General characteristics of halogens. Bonding. Physical and chemical properties. Occurrence, production and applications. Classification and general characteristics of halides. Combinations of halogens with oxygen. Applications. Chapter 4.- GROUP 16: General characteristics of oxygen. Bonding and properties. Ozone. Ozone layer and environmental problems. Occurrence, production and applications. Classification and general characteristics of oxides. Water. Environmental issues. Hydrogen peroxide. SO2, SO3. Sulfuric acid and sulfates. 6

7 Chapter 5.- GROUP 15: Nitrogen. Bonding. Physical and chemical properties. Occurrence, production and applications. Main combinations. Ammonia. Oxides (NO and NO2). Nitric acid: properties, production and applications. Nitrates. Acid rain. Chapter 6.- GROUP 14: Study of Carbon: allotropes, bonding and properties. Occurrence, production and applications. Main compounds: CO and CO2. Carbonic acid and carbonates. Greenhouse effect. II. COORDINATION AND BIOINORGANIC CHEMISTRY Chapter 7.- COORDINATION COMPOUNDS: Types of ligands. Chelate and macrocyclic effects. Stereochemistry and coordination number. Isomerism. Application of bond theories to coordination compounds. Chapter 8.- INTRODUCTION TO BIOINORGANIC CHEMISTRY: Essential elements in biological processes. Oxygen transport. Overview of metal complexes as therapeutic agents. Chapter 9. (Master Class) Bioinorganic chemistry of iron: Haemoglobin. PRACTICAL WORK PROGRAMME: 1. Preparation of simple and double sulfates Iron (II) sulfate heptahydrate Ammonium iron(ii) double sulfate hexahydrate (Mohr s salt). Ammonium copper(ii) double sulfate Ammonium iron alum Potassium aluminum alum 2. Copper(II) sulfate. Reducing power of SO2 and synthesis of copper(i) chloride 3. Synthesis of halides by direct reaction: anhydrous iron(iii) chloride 4. Synthesis of oxides and hydroxides Spinel CoAl2O4 (cobalt blue) Iron(III) and iron(ii) hydroxide Iron(III) oxide Copper(II) hydroxide Nickel(II) hydroxide 5. Synthesis of coordination compounds Potassium tris-(oxalato) ferrate(iii) trihydrate, K3[Fe(C2O4)3]3H2O Tetraammine copper(ii) sulfate monohydrate Stereoisomers 6. Synthesis of bioinorganic compounds Hydroxiapatite 7

8 8. RECOMMENDED READING 1.- ESSENTIAL BIBLIOGRAPHY: HOUSECROFT, C. and SHARPE Alan G. (2012) Inorganic Chemistry, 4 th Edition, Pearson- Prentice Hall, Madrid. MIESSLER, G., FISCHER, P., TARR, D. (2013) Inorganic Chemistry ISBN-13: , 5 th Edition. 2.- ADDITIONAL BIBLIOGRAPHY: GREENWOOD, N.N. y cols (1997) The Chemistry of the Elements. Butterworth-Heinemann Ltd. Oxford. ISBN-13: GUTIERREZ RIOS, E. (2005) Química Inorgánica. Ed. Reverté. Barcelona. ISBN-13: D.F.SHRIVER, P.W.ATKINS, G.H.LANGFORD (2009) Inorganic Chemistry, Oxford University RAYNER-CANHAM, G. (2000) Descriptive Inorganic Chemistry, 2 nd ed., Pearson-Prentice Hall, Mexico D.F. PROBLEMS C.E. HOUSECROFT (2005) Inorganic Chemistry Solutions Manual, Ed. Pearson-Prentice Hall, London. 4.- WEB RESOURCES : Properties of the elements and compounds ( Atomic and molecular orbitals on the web ( Molecule and crystalline structures: Complementary material of HOUSECROFT, C. y cols. (2006) Inorganic Chemistry, REGULATIONS 9. ATTITUDE IN THE CLASSROOM Any irregular act of academic integrity (no reference to cited sources, plagiarism of work or inappropriate use of prohibited information during examinations) or signing the attendance sheet for fellow students not present in class will result in the student not being eligible for continuous assessment and possibly being penalized according to the University regulations. The use of illegal systems during an examination by any means (physical or telematic ones), will be graded as fail with a mark of 0,0 in this examination. In addition, the Faculty will have the option to decide if the student has to be assessed orally in the next exam. The use of documentation provided by the teacher through the Students Portal (presentations, questions, exercises, seminars, practical workbooks) is restricted to the preparation of the subject. Teachers reserve the right to make use of the measures covered by the current Intellectual Property legislation, in cases of misuse and/or unauthorized disclosure of such material. 8