Georgios Pyrgiotakis 99 Hancock St Apt 9, Cambridge, MA Phone: (617)

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1 Georgios Pyrgiotakis 99 Hancock St Apt 9, Cambridge, MA Phone: (617) EDUCATION Ph.D. Materials Science and Engineering, 2006 Dissertation title: Titania Carbon Nanotubes composites for Enhanced Photocatalysis. M.S. Materials Science and Engineering, 2004 Concentration on Electronic Materials B.S. Physics, University of Crete 2000 PROFESSIONAL EXPERIENCE Harvard School of Public Health - Research Fellow present Managed and delegated graduate and undergraduate students working in various research projects, including the synthesis and the characterization of the Engineered Water Nanostructures for airborne bacteria and formites removal, the Safer Formulation Concept for engineered nanoparticles and the use of the Atomic Force Microscope (AFM) study of the nanoparticles interactions in physiological fluids and their correlation to toxicology. Actively participated in pursuing and securing funding for various research studies as a co-principle Investigator: Harvard incubator Fund, 2011 ($50,000); National Science Foundation (NSF), 2012 ($300,000); US Department of Agriculture (USDA), 2013 ($500,000) Managed the Laboratory of Nano Particle Sciences in day-to-day operations through procurement of materials, assurance of safety protocols, maintenance of instrumentation and construction of systems to simulate real world microenvironments. Developed the website of the Center of the Nanotechnology and Nanotoxicology and actively participated in the organization of the Center s Seminar series and International Symposia. Particle Engineering Research Center at the - Researcher Initiated strong interdisciplinary collaborations for the purpose to integrated data mining techniques with Raman spectroscopy to evaluate in real-time nanoparticle cell interaction, discriminate cell lines and cellular death pathways that continue to be active. Created two creative educations paradigms while teaching graduate level courses: An engaging and intuitive paint lab, which effectively deepened the acquired class knowledge by integrating arts with science, and an innovative undergraduate course, Nano for the Rest Of Us, which introduced the applications and implications of nanotechnology to students of non- science fields. Interacted with the industrial partners of the Particle Engineering Research Center on monthly base to build collaborations and foster partnerships. Department of Materials Science & Engineering - Graduate Research Assistant Worked in various project on the nanoparticle synthesis and characterization including, the development of advanced photocatalytic materials based on carbon structures, the measured the Mechanical Behavior of Spores and Bacteria by AFM and the quantification of the interactions potential between micro/nano-particles and polymer with the Colloidal AFM Probe Technique. Teaching Assistant at the courses of Materials Selection and Failure Analysis (Spring 2002) and Synthesis and Characterization of Electronic Materials (Fall 2001) and Participate in the outreach programs MSE Teach and E-fair. AWARDS / DISTINCTIONS Marie Curie Fellow, European Research Council 2011 President of UF Chapter of KERAMOS, Fellowship from the Department of Materials Science and Engineering Graduate Research Scholarship in Physics, University of Crete

2 SOCIETY MEMBERSHIPS American Ceramic Society (ACerS) KERAMOS, Materials Research Society (MRS) Society of Mining Engineering (SME) Sustainable Nanotechnology Organization (SNO) GRANTS NSF INSPIRE, PI: Dr. P Demokritou (2013) Co-PI Pending USDA/NIFA Nanotechnology for Agricultural and Food Systems, PI: Dr. P Demokritou (2013) Co-PI NSF Nano-manufacturing, PI: Dr. P Demokritou (2012) Participation Harvard Incubator Fund, PI: Dr. P Demokritou (2011) Lead Author Marie Curie Career Integration Grant, PI G. Pyrgiotakis (2011) Lead Author NSF I/UCRC supplementary grant, PI Dr. B. Moudgil (2009) Lead author PUBLICATIONS Peer Reviewed Journal Articles 1. Pirela, S.; Pyrgiotakis, G.; Dhimiter, B.; Treye, T.; Castranova, V.; Demokritou, P. Development and Characterization of an Exposure Platform Suitable for Physico-Chemical, Morphological and Toxicological Characterization of Printer Emitted Particles (PEPs). Inhalation Toxicology Accepted 2. Pyrgiotakis, G.; McDevitt J. Gao Y.; Branco A; Eleftheriadou M; Lemos B.; Nardell E.; Demokritou P. An emerging, chemical free nanotechnology based approach for the inactivation of Mycobacteria using Engineered Water Nanostructures (EWNS). Nanomedicine -NBM Accepted 3. Watson, C.; Ge, J.; Cohen, J.; Pyrgiotakis, G.; Engelward, B. P.; Demokritou, P. A High Throughput Screening Platform for Engineered Nanoparticle Mediated Genotoxicity Using CometChip Technology. ACS Nano Accepted 4. DeLoid, G.; Cohen, J. M.; Darrah, T.; Pyrgiotakis, G.; Wohlleben, W.; Demokritou, P. Nanomaterial Effective Density for In Vitro Dosimetry by Volumetric Centrifugation., Nature Communications Accepted 5. G. A. Sotiriou, C. Watson, K. M. Murdaugh, T. H. Darrah, G. Pyrgiotakis, A. Elder, J. D. Brain and P. Demokritou. Engineering Safer-by-Design, Transparent, Silica-coated ZnO Nanorods with Reduced DNA Damage Potential. Environmental Science: Nano in press, DOI: /C3EN00062A (2014). 6. Pyrgiotakis, G; McDevitt, J; Bordini, A; Diaz, E; Molina, R; Watson C; Lenard S; Fix N; Mizuyama Y; Brain J; Demokritou P. A Nanotechnology-based Method for Airborne Bacterial Inactivation using Engineered Water Nanodroplets. RSC Environmental Science: Nano, 2014, 1, Pyrgiotakis, G; Blattmann, C.O.; Pratsinis, S.E.; Demokritou, P. Nanoparticle-nanoparticle interactions in biological media by Atomic Force Microscopy, Langmuir 2013, 29, Demokritou, P.; Gass, S.; Pyrgiotakis, G.; Cohen, J. M.; Goldsmith, W.; McKinney, W.; Frazer, D.; Ma, J.; Schwegler-Berry, D.; Brain, J.; et al. An in Vivo and in Vitro Toxicological Characterisation of Realistic Nanoscale CeO2 Inhalation Exposures. Nanotoxicology 2013, 7, S. Gass, J. M. Cohen, G. Pyrgiotakis, G. A. Sotiriou, S. E. Pratsinis and P. Demokritou. Safer Formulation Concept for Flame-Generated Engineered Nanomaterials. ACS Sustainable Chemistry & Engineering 2013, 1, Pyrgiotakis, G.; McDevitt, J.; Yamauchi, T.; Demokritou, P. A Novel Method for Bacteria Inactivation Using Engineered Water Nanostructures. J. Nanopart. Res. 2012, Cohen, J.; DeLoid, G.; Pyrgiotakis, G.; Demokritou, P. Interactions of Engineered Nanomaterials in Physiological Media and Implications for in Vitro dosimetry. Nanotoxicology 2012, 7, Guarracino, M. R.; Xanthopoulos, P.; Pyrgiotakis, G.; Tomaino, V.; Moudgil, B. M.; Pardalos, P. M. Classification of Cancer Cell Death with Spectral Dimensionality Reduction and Generalized Eigenvalues. Artif. Intell. Med. 2011, 53,

3 13. Pyrgiotakis, G.; Kundakcioglu, O. E.; Pardalos, P. M.; Moudgil, B. M. Raman Spectroscopy and Support Vector Machines for Quick Toxicological Evaluation of Titania Nanoparticles. J Raman Spectrosc 2011, 42, Karaka, F.; Pyrgiotakis, G.; Çelik, M.; Moudgil, B. M. Na-Bentonite and MgO Mixture as a Thickening Agent for Water-Based Paints. KONA Powder and Particle Journal 2011, 29, Fenn, M. B.; Xanthopoulos, P.; Pyrgiotakis, G.; Grobmyer, S. R.; Pardalos, P. M.; Hench, L. L. Raman Spectroscopy for Clinical Oncology. Adv. Opt. Tech. 2011, 2011, Sharma, P.; Brown, S. C.; Singh, A.; Iwakuma, N.; Pyrgiotakis, G.; Krishna, V. B.; Knapik, J. A.; Barr, K.; Moudgil, B. M.; Grobmyer, S. R. Near-Infrared Absorbing and Luminescent Gold Speckled Silica Nanoparticles for Photothermal Therapy. J. Mater. Chem. 2010, 20, Pyrgiotakis, G.; Sigmund, W. M. X-Ray Photoelectron Spectroscopy of Anatase-TiO2 Coated Carbon Nanotubes. SSP 2010, 162, Pyrgiotakis, G.; Kundakcioglu, O. E.; Finton, K.; Pardalos, P. M.; Powers, K.; Moudgil, B. M. Cell Death Discrimination with Raman Spectroscopy and Support Vector Machines. Ann. Biomed. Eng. 2009, 37, Woan, K.; Pyrgiotakis, G.; Sigmund, W. M. Photocatalytic Carbon-Nanotube-TiO2 Composites. Adv. Mater. 2009, 21, Bhowmick, T. K.; Pyrgiotakis, G.; Finton, K.; Suresh, A. K.; Kane, S. G.; Moudgil, B. M.; Bellare, J. R. A Study of the Effect of JB Particles onsaccharomyces Cerevisiae(Yeast) Cells by Raman Spectroscopy. J Raman Spectrosc 2008, 39, Pyrgiotakis, G.; Bhowmick, T. K.; Finton, K.; Suresh, A. K.; Kane, S. G.; Bellare, J. R.; Moudgil, B. M. Cell (A549)-Particle (Jasada Bhasma) Interactions Using Raman Spectroscopy. Biopolymers 2008, 89, Sigmund, W. M.; Yuh, J.; Park, H.; Maneeratana, V.; Pyrgiotakis, G.; Daga, A.; Taylor, J.; Nino, J. Processing and Structure Relationships in Electrospinning of Ceramic Fiber Systems. J. Am. Chem. Soc. 2006, 89, Kim, B.; Pyrgiotakis, G.; Sauers, J.; Sigmund, W. The Effect of Monolayers' Alkyl Chain Length on Atomic Force Microscopy Anodization Lithography. Colloid Surface A 2005, 253, Cho, J.-M.; Pyrgiotakis, G.; Sigmund, W. M. Surface Forces on Nanoparticles Determined by Direct Measurement. In Dekker Encyclopedia of Nanoscience and Nanotechnology; Marcel Dekker, Inc., 2004; pp Lee, S.; Pyrgiotakis, G.; Sigmund, W. M. TiO2-Carbon Nanotube Nanocomposite Particles. Journal of the European Academy of Sciences 2004, Manjooran, N.; Lee, S.; Pyrgiotakis, G.; Sigmund, W. Ceramic Slurries for Electrodeposition in Rapid- Prototyping Applications. Am. Ceram. Soc. Bull. 2004, 83, Kim, B.; Pyrgiotakis, G.; Sigmund, W. Dip-Pen Nanolithography with Poly(Diallyl Dimethyl Ammonium) Chloride. J. Nanosci. Nanotechn. 2004, 4, Submitted 28. Pyrgiotakis G.; Blattmann C.; Demokritou P.; Real-time Nanoparticle-Cell interactions in physiological media by Atomic Force Microscopy. Submitted to ACS Sustainable Engineering & Chemistry Okello, V.; Gass, S.; Pyrgiotakis, G.; Nian, D.; Mudaugh, K.; Boling, D.; Demokritou, P. Capture, Isolation and Detection of Industrially-relevant Engineered Aerosol Nanoparticles, Submitted to Langmuir Book Chapters 1. Pyrgiotakis, G. Carbon Nanostructures for Enhanced Photocatalysis for biocidal applications, Handbook of Nanomaterials Properties Editors: W. Sigmund, M. Shanmugam and V. Zinyuk Spinger, In Press 2. Pyrgiotakis, G.; Sigmund, W. Photocatalytic Particles for Biocidal Applications, Particulate Systems in nanoand bio- technologies. Editors: W. Sigmund, H. El-Shall, D.O. Shah and B. Moudgil. RCR Press, 2008 ISBN: Sigmund, W.; Pyrgiotakis, G.; Daga, A. Theory and Applications of Colloidal Processing, Chemical Processing of Ceramics, 2nd Edition, Editors: Burtrand I. Lee and Sridhar Komarneni, CRC Press, 2005 ISBN:

4 4. Cho, J.; Pyrgiotakis, G.; Sigmund, W. Surface Forces on Nanoparticles Determined by Direct Measurement, Dekker Encyclopaedia of Nanoscience and Nanotechnology and Nanoscience, Editors H. Nalwa, DOI: /E- ENN , by Marcel Dekker Inc Patents 1. Sigmund, W.; Lee, S.-H.; Koopman, B.; Moudgil, B. M.; Pyrgiotakis, G.; Krishna, V. B. Photocatalytic Nanocomposites and Applications Thereof Patent Number 7,541, Sigmund, W.; Daga, A.; Yuh J.; Pyrgiotakis G.; Taylor.J.J; Park H; Ceramic nanoparticles and methods for forming ceramic nanoparticles from electrospun nanofibers 2006 Application Number WO A2 Peered Reviewed Proceedings 1. Gass, S.; Pyrgiotakis, G.; Cohen, J.M.; Sotiriou, G.A.; Pratsinis, S.E.; Demokritou, P. A safer formulation concept for flame-generated engineered nanomaterials, Nanotech 2012 Conference Proceedings Vol. 3, ISBN: , 2012, p Pyrgiotakis, G.; McDevitt, J.; Yamauchi, T.; Demokritou, P. A novel method for bacteria inactivation using Engineered Water Nanostructures. Nanotech 2012 Conference Proceedings Vol. 1, ISBN: , 2012, p , 3. Pyrgiotakis, G.; Sigmund, W.; Titania-Carbon Nanotube Composite for Enhanced Photocatalysts, 2nd International Conference & Exposition on Advanced Ceramics & Composites, Daytona Beach, Sigmund, W.; Pyrgiotakis, G.; Krishna, V.; Lee, S.-H.; Pumprueg, S.; Koopman, B.; Moudgil, B. Photocatalytic Destruction of Bioparticles, IEEE International Conference, Proceedings TEHOSS 2005, Ed. A. Stepnowski, Co-Eds. A Rucinski, K. Kosmowski, ISBN ,, 2005, p Pyrgiotakis, G.; Sigmund, W.; Advanced Photocatalysis with Anatase Nanocoated Multi-walled Carbon Nanotubes. Proceedings of MRS Spring Meeting 2005: Symposium R Nanoporous and Nanostructured Materials for Catalysis, Sensor, and Gas Separation Applications, Editors: S.W. Lu, H. Hahn, J. Weissmuller, J.L. Gole, San Francisco, 2005, p. R Manjooran, N.J.; Lee, S.-W.; Pyrgiotakis, G.; Sigmund, W.; Rheology of Ceramic Slurries for Electro- Deposition in Rapid Prototyping Applications. Proceedings of ACerS Meeting 2004: Colloidal Ceramic Processing of Nano-, Micro-, and Macro-Particulate Systems, Editors: W.-H. Shih, Y. Hirata, W. Carty, 2004, p INVITED PRESENTATIONS 1. Title: Engineered Water Nanostructures: Synthesis and Applications Location: Harvard School of Public Health - Harvard University Date: January 12, 2013 Inviter: Dr. Lester Kobzick 2. Title: bioraman - Probing nanoparticle cell interactions Location: Department of Science of Materials - University of Patras Date: September 12, 2009 Inviter: Dr. N. Vainos 3. Title: bioraman single cell probing tool Location: Center of Applied Optimization - Industrial and System Engineering Date: April 7, 2009 Inviter: Dr. P. Pardalos 4. Title: Titania - Carbon Nanotube Composites for advanced photocatalysis Location: Foundation of Research and Technology at Heraklion, Crete, Greece Date: January 17, 2007 Inviter: Dr. A. Lappas CONFERENCES Organized Conferences 1. Conference: International Conference on Biomedical Data & Knowledge Mining: Towards Biomarker

5 Discovery, Chania, Crete, July 7-9, 2010 Conference/Meeting Presentations (poster presentations are not included) 1. MRS Fall Meeting, Boston, MA, December 1-6, 2013 Enhancing Engineering Research Skills through Art 2. MRS Fall Meeting, Boston, MA, December 1-6, 2013 Development of AFM Platform for Directly Measuring the Nanoparticle-Nanoparticle and Nanoparticle-Cell Interactions 3. Sustainable Nanotechnology Organization Conference, Arlington, VA, November 3-5, 2013 Development of AFM Platform for Directly Measuring the Nanoparticle-Nanoparticle and Nanoparticle-Cell Interactions 4. MRS Fall Meeting, Boston, MA, November 25-30, 2012 A safer formulation concept for flame-generated engineered nanomaterials (ENMs) 5. Sustainable Nanotechnology Organization Conference, Arlington, VA, November 4-6, 2012 A novel method for bacteria inactivation using Engineered Water Nanostructures. 6. Nano-Symposium: Nanotechnology and Engineered Nanomaterials: Applications and Environmental Health implications, Kyoto, Japan, September 24, 2012 Engineered Water NanoStructures (EWNS) Physicochemical Characterization and Antimicrobial Applications 7. Nano-Symposium: Working towards a sustainable nanotechnology industry: The importance of industryacademia partnerships in addressing nano-ehs matters, Boston, MA, June 13, 2012 Engineered Water Nanostructures Synthesis, characterization and applications NSTI Nanotechnology Conference & Expo, Santa Clara, CA, June 19-21, 2012 A novel method for bacteria inactivation using Engineered Water Nanostructures. 9. International Conference on Biomedical Data & Knowledge Mining: Towards Biomarker Discovery, Chania, Crete, July 7-9, 2010 Support Vector Machines in Spectroscopy: Seeing inside the Cell 10. I/UCRC Meeting, Gainesville, FL, February 18-22, 2010 A Fundamental Study of Nanoparticle Protein Mutual Interactions: Role of Nanoparticle Morphology and Size - Part II 11. I/UCRC Meeting, New York, NY, August 20, 2009 A Fundamental Study of Nanoparticle Protein Mutual Interactions: Role of Nanoparticle Morphology and Size - Part I th International Conference and Surface and Colloid Science (ICSCS) & 83rd ACS Colloid and Surface Science Symposium, June 14 - June , New York, NY, USA bioraman: in-situ Monitoring of Particle-Cell Interaction - Case study: Gold Speckled Silica 13. SME Meeting Denver, February 23-25, CO, 2009 Characterization of Bioreactivity of Particles Using the BioRaman Technique 14. MRS Spring Meeting, San Francisco, March 24-28, CA, 2008 bioraman: An in-situ method for investigating the particle-cell interaction 15. PERC IAB Meeting, Gainesville, FL, April 13-14, 2007 Whole Real Time Cell Toxicity Through bioraman 16. MRS Spring Meeting, San Francisco, CA, 2005 Advanced Photocatalysis With Anatase Nanocoated Multi-Walled Carbon Nanotubes th ACerS Meeting, Baltimore, MA, April 10-13, 2005, Advanced Photocatalytic Composites: Anatase Coated CNTs. 18. PERC/NSF IAB meeting September 22-23, 2004, Gainesville, FL. Advanced Photocatalytic Systems for Destructions of Hazardous Microbes: Anatase Coated CNTs and TiO2 Nanofibers 19. PERC/NSF IAB meeting, Gainesville, FL, September 3-4, 2003, Photocatalytic Nanocomposites: A Synthesis and Characterization. 20. PERC/NSF IAB meeting, Gainesville, FL, February 18-19, 2003, Surface Forces for Nanosize Particles. EXPERTISE

6 Instrumentation Skills: Transmission Electron Microscopy (TEM, Zeiss Libra 120, JEOL 2010), Scanning Electron Microscope (SEM), Atomic Force Microscope (Asylum and Digital Instrument), Xray Photoelectron Spectroscopy (XPS), X-Ray Diffraction (XRD), Raman Spectroscopy, FTIR Spectroscopy, Dynamic Light Scattering (DLS), Light Scattering, UV/VIS adsorption reflectance and scattering Cell Culture techniques: culture of animal cells, toxicological assays Lactate Dehydrogenase (LDH), MTT, XTT, Confocal, Epifluorescent and light Microscope. Technical Skills: Engineering Design, Image Analysis, Statistical Analysis, Design of Experiment, CAD, Web publishing Computer Skills: Mathematica, Fortran 77/90, Microsoft Office Suit, HTML, WordPress REFERENCES Available Upon Request

7 ! REFERENCES Philip Demokritou Ascociate Professor, Environmental Health Harvard School of Public Health Joseph Brain Cecil K. and Philip Drinker Professor, Environmental Health Harvard School of Public Health 665 Huntington Avenue 665 Huntington Avenue Building 1, Room 1310B Building 1, Room 1308A Boston, Massachusetts Boston, Massachusetts Phone: (617) Phone: (617) Fax: (617) Fax: (617) Brij Moudgil (also teaching reference) Alumni Professor, Materials Science & Engineering Director, Particle Engineering Research Center Panos Pardalos Professor, Industrial and System Engineering!!205 Particle Science & Technology 303 Weil Hall! P.O. Box P.O. Box ! Gainesville, Florida Gainesville, Florida, Phone: (352) Phone: (352) Fax: (352) Fax: (352) ! Wolfgang Sigmund Professor, Materials Science & Engineering Ben Koopman Professor, Environmental Engineering!!225 Rhines Hall 322 Black Hall!P.O. Box P.O. Box !Gainesville, Florida Gainesville, Florida, Phone: (352) Phone: (904) Fax: (352) Fax: (904) !