Nanocrystalline Cellulose:

Size: px
Start display at page:

Download "Nanocrystalline Cellulose:"

Transcription

1 Nanocrystalline Cellulose: International Standardization & Metrological Approaches Alan Steele National Research Council Institute for National Measurement Standards TAPPI International Conference on Nano for Renewable Materials Workshop on International Standards June 9, 2011

2 Nanotechnology What is it? SI Unit of Length: 1 nm = 10-9 m Atomic sizes and lattice spacings are smaller particle ~ 10 fm neutral He atom ~ 30 pm neutral Fe atom ~ 150 pm lattice ~ 0.2 nm to 0.8 nm Biological size range proteins ~ 1 to 10 nm DNA radius ~ 2.5 nm viruses ~ 10 to 100 nm cells ~ 1 μm to 100 μm

3 Policy, Standards and Metrology Many countries are participating in international development of policy, standards and metrology for nanotechnologies through established channels and organizations

4 OECD : Intergovernmental Policy Organisation for Economic Cooperation and Development governmental organization working to ensure that that potential safety issues are being addressed at the same time as nanotechnology is developing Working Party on Nanotechnology advising on emerging policy issues Working Party on Manufactured Nanomaterials focus on testing ti and assessment methods

5 Nine projects currently active: database on EHS research research strategies on manufactured nanomaterials safety testing of a representative set of manufactured nanomaterials environmental applications OECD : WPMN manufactured nanomaterials and test guidelines co-operation on voluntary schemes and regulatory programmes exposure measurement and exposure mitigation alternative methods in nanotoxicology co-operation on risk assessment

6 OECD : WPMN Sponsorship Program NANOMATERIALS (13) fullerenes (C60) single-walled carbon nanotubes multi-walled carbon nanotubes silver nanoparticles gold nanoparticles iron nanoparticles carbon black titanium dioxide cerium oxide zinc oxide silicon dioxide dendrimers nanoclays END POINTS information / identification 9 parameters physical-chemical properties and material characterization 17 parameters environmental fate 15 parameters environmental toxicology 6 parameters mammalian toxicology 9 parameters material safety 3 parameters

7 ISO : Documentary Standards Technical Committee 229: Nanotechnologies supporting sustainable and responsible development of nanotechnologies improving quality, safety, security, consumer and environmental protection involves experts from about 40 countries formal working liaisons with another 18 ISO TCs and 7 international organizations including OECD, BIPM, EU, IRMM, VAMAS

8 ISO TC229 Working Group Structure JWG1 Terminology & Nomenclature (Canada) core term definitions JWG2 Metrology & Characterization (Japan) experimental techniques and protocols WG3 Health, Safety, Environment (USA) human and environmental toxicology protocols WG4 Material Specifications (China) heading down the path to product specs

9 nanoscale (Draft) Definitions from ISO one or more spatial dimensions in the range from 1 nm to 100 nm nanoscience the systematic study and understanding of matter, properties and phenomena related to the nanoscale nanotechnology the application of scientific knowledge to control and utilize matter at the nanoscale, where sizerelated properties and phenomena can emerge

10 TC229 Metrology Checklist Simple Questions: Clear material description Clear measurand Measurement unit Traceable measurements Defined method Validated method Available instrumentation Quality assurance tools Uncertainty budget

11 Pre-Normative Metrology Research Publication on SWCNT sample preparation protocols for 10 analytical techniques by NRC, NIST, NPL

12 TC229 WG3 Project 5 : Measurands NANOMATERIALS (8) Fullerenes Carbon nanotubes Titanium dioxide Calcium carbonate Zinc oxide Silicon dioxide Nickel Quantum dots CHARACTERISTICS (9) Agglomeration state Surface area Composition Surface chemistry Particle size distribution Shape Purity / Impurity Solubility Stability

13 Reference Materials Reference materials will be an important method to bring metrology and quality to the nanoscale ISO Guide 34 is the standard for producers homogeneity and stability are essential both physical and chemical properties important objective is reproducibility and process control Certified reference materials go even further validated uncertainty statements enable use as check standards or process calibration

14 Reference Material Defined Material, sufficiently homogeneous and stable with respect to one or more specified properties, which has been established to be fit for its use in a measurement process ISO Definition of Reference Material NIST offers over two thousand RM and SRMs includes nanoscale reference materials such as gold nanoparticles and single-walled carbon nanotubes

15 Reference Material Production Produce a homogeneous source of material Develop characterization tests and measurements Evaluate optimal packaging and storage conditions Prepare sufficient material for current / future needs Make material available to industry and toxicologists

16 NRC and FPInnovations: NCC RM Candidates Nanocrystalline cellulose (both dry and in solution) Homogenization and bottling Radiation sterilization with 10 kgy gamma rays Homogeneity testing Characterization testing with collaborators Data analysis, review and reporting

17 Nanocrystalline Cellulose Reference Materials NCC-1: 1 g bottles dry powder NCCS-1: 20 ml bottles 6% solution Measurands: crystal structure particle size distribution molecular weight elemental analysis carboxylic acid content zeta potential (solution only) surface characterization

18 Nanocrystalline Cellulose Reference Materials NCC-1: 1 g bottles dry powder NCCS-1: 20 ml bottles 6% solution Collaborators: FPInnovations NRC NIST NCI Virginia Tech Tokyo University McGill University INP-Pagora Grenoble INNVENTIA AB Stockholm North Carolina State University

19 Toxicology Studies on NCC Toxicity risk assessment is being conducted by FPInnovations under Canada s New Substances Notification Regulations (Health & Environment)

20 Conclusions One major obstacle to adequate characterization of engineered nanoparticles is the lack of scientifically credible nanoscale reference materials useful for validation and development of exposure assessment tools (instruments, protocols, methods) essential for standardization of toxicological evaluations (materials, protocols). A comprehensive approach to metrology and standardization will benefit NCC commercialization

21 Some things I didn t talk about International Metrology Workshops Coordinated EU effort in nanoscale metrology Reference Material Database Minimum characterization suite for toxicity

22 SWCNT: Reference Material / OECD Sample NRC has early-stage reference material for high quality laser-produced single wall carbon nanotubes kg quantities of material known to be homogeneous oge eous for use in toxicity testing are required by OECD mg bottles of material in powder form are being characterized by ICPMS, TGA, Raman, etc. in an international collaboration led by INMS

23 Gold Nanoparticles NIST offers 3 reference materials for gold nanoparticles: 10 nm, 30 nm and 60 nm diameter Mean GNP diameter is characterized using six techniques Summary ypresentation by Vince Hackley available at 60 nm gold nanoparticles Atomic Force Microscopy Scanning Electron Microscopy Transmission Electron Microscopy Dynamic Light Scattering Electrospray-Differential Mobility Analysis Small Angle X-Ray Scattering

24 Gold Nanoparticle RM Data

25 Gold Nanoparticle RM Data The six different measurement techniques give nominal diameters that do not agree within their expanded uncertainties! This is VERY GOOD SCIENCE!! This is VERY GOOD SCIENCE!! These are VERY DIFFERENT MEASURANDS!!!

Peter Kearns, PhD OECD, ENV/EHS BIPM, April 2015

Peter Kearns, PhD OECD, ENV/EHS BIPM, April 2015 EXPOSURE MEASUREMENT AND EXPOSURE MITIGATION: ACTIVITIES OF OECD S WORKING PARTY ON MANUFACTURED NANOMATERIALS Peter Kearns, PhD OECD, ENV/EHS BIPM, April 2015 Areas covered by the OECD Programme Testing

More information

Standards for Physico-Chemical Measurements of Nanomaterials

Standards for Physico-Chemical Measurements of Nanomaterials Standards for Physico-Chemical Measurements of Nanomaterials Debra L. Kaiser Technical Program Director Material Measurement Laboratory, NIST, US February 15, 2017 Outline of Presentation Introduction

More information

Communicating business-to-business product information Dr. Markus Pridöhl

Communicating business-to-business product information Dr. Markus Pridöhl Communicating business-to-business product information Dr. Markus Pridöhl Brussels, Oct 2 nd 2008 Manufactured nanomaterials according to OECD Elemental nanomaterials Fullerenes (C 60 ) Multi-walled carbon

More information

International Standardization for Measurement and Characterization of Nanomaterials

International Standardization for Measurement and Characterization of Nanomaterials 2012/SOM2/SCSC/CON/008 International Standardization for Measurement and Characterization of Nanomaterials Submitted by: Japan 9 th Conference on Standards and Conformance in the Field of Innovations and

More information

Environmental Risk Assessment of Nanomedicines

Environmental Risk Assessment of Nanomedicines Environmental Risk Assessment of Nanomedicines Specific methodological issues and implications for risk assessment Silvia Berkner, Petra Apel Umweltbundesamt, Germany Outline Regulatory background Current

More information

A Minimal Set of Characterization Parameters

A Minimal Set of Characterization Parameters A Minimal Set of Characterization Parameters Ensuring Appropriate Material Characterization in Nano-Toxicity Studies: A Workshop October 28, 2008 Nigel Walker, Ph.D. National Toxicology Program Washington,

More information

Regulating Nanotechnologies in the EU and US: Towards Effectiveness and Convergence

Regulating Nanotechnologies in the EU and US: Towards Effectiveness and Convergence the EU and US: Towards Effectiveness and Convergence Project Consortium: London School of Economics (LSE) Chatham House Environmental Law Institute (ELI) Project on Emerging Nanotechnologies (PEN) Project

More information

Canada s Experience with Chemicals Assessment and Management and its Application to Nanomaterials

Canada s Experience with Chemicals Assessment and Management and its Application to Nanomaterials Canada s Experience with Chemicals Assessment and Management and its Application to Nanomaterials European Chemicals Agency (ECHA) Topical Scientific Workshop: Regulatory Challenges in Risk Assessment

More information

Characterization Methods of Manufactured Nanomaterials for EHS Studies

Characterization Methods of Manufactured Nanomaterials for EHS Studies Characterization Methods of Manufactured Nanomaterials for EHS Studies Steven W Brown, MS, CIH International Standards Organization Technical Committee #229 on Nanotechnologies Convener Work Group #3 Environmental

More information

European Chemicals Agency (ECHA)Topical Scientific Workshop: Regulatory Challenges in Risk Assessment of Nanomaterials

European Chemicals Agency (ECHA)Topical Scientific Workshop: Regulatory Challenges in Risk Assessment of Nanomaterials European Chemicals Agency (ECHA)Topical Scientific Workshop: Regulatory Challenges in Risk Assessment of Nanomaterials Jim Alwood - Office of Pollution Prevention and Toxics October 23, 2014 Legislation

More information

EUROPEAN COMMISSION ENTERPRISE AND INDUSTRY DIRECTORATE-GENERAL

EUROPEAN COMMISSION ENTERPRISE AND INDUSTRY DIRECTORATE-GENERAL EUROPEAN COMMISSION ENTERPRISE AND INDUSTRY DIRECTORATE-GENERAL Consumer goods Brussels, 2 nd February 2010 M/461 EN MANDATE ADDRESSED TO CEN, CENELEC AND ETSI FOR STANDARDIZATION ACTIVITIES REGARDING

More information

State-of-the-science in Metrology & Metrics for Nanomaterials Regulation

State-of-the-science in Metrology & Metrics for Nanomaterials Regulation Topic 3: Metrology and dose metrics for hazard and exposure assessment throughout the life cycle State-of-the-science in Metrology & Metrics for Nanomaterials Regulation Dr Steve Hankin Head of Section,

More information

Nanomaterials, REACH and CLP - what is going on at the regulatory front

Nanomaterials, REACH and CLP - what is going on at the regulatory front Nanomaterials, REACH and CLP - what is going on at the regulatory front NanoKokkola 23 September 2014 Outi Tunnela Helpdesk Unit European Chemicals Agency EU Approach to Nanotechnologies Safe: ensure a

More information

VAMAS and Nanotechnology Steve Freiman VAMAS Secretary National Standards Panel December 5, 2013

VAMAS and Nanotechnology Steve Freiman VAMAS Secretary National Standards Panel December 5, 2013 VAMAS and Nanotechnology Steve Freiman VAMAS Secretary National Standards Panel December 5, 2013 What is VAMAS? Formed as one of 18 cooperative projects at the1982 Economic Summit of the GATT 7 to stimulate

More information

Nanomaterials under REACH

Nanomaterials under REACH Nanomaterials under REACH ECHA Workshop on nanomaterials, 30-31 May 2012, Helsinki Maila Puolamaa and Andrej Kobe Overview REACH aims and legal basis CA/59/2008 : Nanomaterials in REACH Activities at EU

More information

Carbon Nanotube Reference Materials and Characterization Jeffrey A. Fagan

Carbon Nanotube Reference Materials and Characterization Jeffrey A. Fagan Carbon Nanotube Reference Materials and Characterization Jeffrey A. Fagan National Institute of Standards and Technology Gaithersburg, MD Nanotube Market Composites Energy Electronics Chemical & Engineering

More information

Unilever s approach to assuring the safety of novel nanomaterials - supporting the risk assessment science

Unilever s approach to assuring the safety of novel nanomaterials - supporting the risk assessment science Unilever s approach to assuring the safety of novel nanomaterials - supporting the risk assessment science Bobbie Bradford Safety & Environmental Assurance Centre Unilever s brands Unilever s Mission is

More information

Trends in the Sound Management of Chemicals Perspectives from Asia and Pacific

Trends in the Sound Management of Chemicals Perspectives from Asia and Pacific Trends in the Sound Management of Chemicals Perspectives from Asia and Pacific 3 rd and 4 th Dec. 2009 Yoshiaki TOTOKI Waste Management and Resources Project Institute for Global Environmental Strategies

More information

Nanomaterials and Nanotechnology. Regulatory Update

Nanomaterials and Nanotechnology. Regulatory Update Nanomaterials and Nanotechnology Regulatory Update Shaun F. Clancy, Ph.D. October 21, 2015 My perspective is informed by. Employment by a chemical company that manufactures both large volume and specialty

More information

ASTM International Committee E56 on Nanotechnology

ASTM International Committee E56 on Nanotechnology ASTM International Committee E56 on Nanotechnology http://www.astm.org/commit/committee/e56.htm Debra L. Kaiser Material Measurement Laboratory, NIST Vice-Chair, Committee E56 ANSI Panel Meeting February

More information

Regulation of Nanomaterials in Consumer Products A European Perspective

Regulation of Nanomaterials in Consumer Products A European Perspective FEDERAL INSTITUTE FOR RISK ASSESSMENT Regulation of Nanomaterials in Consumer Products A European Perspective Andreas Luch Nanomaterials: What is so Special about the Nanoscale? 0.1 1 Water molecule Glucose

More information

Exposure to Nanomaterials:

Exposure to Nanomaterials: Exposure to Nanomaterials: Challenges and Lessons form the Workplace Charles L. Geraci, Ph.D., CIH Centers for Disease Control and Prevention National Institute for Occupational Safety and Health Toward

More information

Overview of LNE s activities led in aerosol metrology

Overview of LNE s activities led in aerosol metrology Overview of LNE s activities led in aerosol metrology Tatiana Macé Laboratoire National de métrologie et d Essais LNE s STRATEGY FOR NANOPARTICLES Aerosols metrology (generation, characterization,..) Environment

More information

Nanomaterials and waste water treatment Opportunities and issues to consider

Nanomaterials and waste water treatment Opportunities and issues to consider Nanomaterials and waste water treatment Opportunities and issues to consider Dr David Carlander Engineered nanomaterials in the waste water treatment process and associated environments NanoForum 2013

More information

Standards and their value in general and specifically for nanotechnology

Standards and their value in general and specifically for nanotechnology Standards and their value in general and specifically for nanotechnology Charles Clifford, Surface Technology Group, National Physical Laboratory charles.clifford@npl.co.uk Denis Koltsov, Chair ISO TC229

More information

ISO/TR TECHNICAL REPORT. Nanotechnologies Methodology for the classification and categorization of nanomaterials

ISO/TR TECHNICAL REPORT. Nanotechnologies Methodology for the classification and categorization of nanomaterials TECHNICAL REPORT ISO/TR 11360 First edition 2010-07-15 Nanotechnologies Methodology for the classification and categorization of nanomaterials Nanotechnologies Méthodologie de classification et catégorisation

More information

Aerosol Generation and Characterisation for Nanotoxicology

Aerosol Generation and Characterisation for Nanotoxicology Aerosol Generation and Characterisation for Nanotoxicology Alison Buckley Airborne Radioactivity Monitoring Users Group Meeting, NPL, Teddington 16 th November 2011 Introduction HPA Role The Health Protection

More information

ISO/IEC requirements. General matters of quality system, requirements for documentation and the list of the documents required for a

ISO/IEC requirements. General matters of quality system, requirements for documentation and the list of the documents required for a ISO/IEC 17025-2006 requirements. General matters of quality system, requirements for documentation and the list of the documents required for a quality system package: quality policy, quality manual, quality

More information

NANOTECHNOLOGY SOLID WASTE IMPLICATIONS. Gurumurthy Ramachandran. University of Minnesota

NANOTECHNOLOGY SOLID WASTE IMPLICATIONS. Gurumurthy Ramachandran. University of Minnesota NANOTECHNOLOGY SOLID WASTE IMPLICATIONS Gurumurthy Ramachandran University of Minnesota Engineering at the Atomic Level: Scanning Tunneling Microscopy Manipulating atoms Writing with atoms. D.M. Eigler,

More information

Normenliste Nanotechnologie 1

Normenliste Nanotechnologie 1 Normenliste Nanotechnologie 1 Diese Normenliste ist bei der Studie zu berücksichtigen sowie gegebenenfalls zu vervollständigen. Die Auflistung ist auf Englisch mit dem Stand vom Juni 2015. Norm Titel Komitee

More information

TECHNICAL SPECIFICATION

TECHNICAL SPECIFICATION TECHNICAL SPECIFICATION ISO/TS 13278 First edition 2011-11-01 Nanotechnologies Determination of elemental impurities in samples of carbon nanotubes using inductively coupled plasma mass spectrometry Nanotechnologies

More information

Perspectives on Mitigating Exposures to Engineered Nanomaterials in the Workplace

Perspectives on Mitigating Exposures to Engineered Nanomaterials in the Workplace Perspectives on Mitigating Exposures to Engineered Nanomaterials in the Workplace Pat Rasmussen Exposure & Biomonitoring Division, Healthy Environments and Consumer Safety Branch, Health Canada Adjunct

More information

The National Nanotechnology Initiative

The National Nanotechnology Initiative The National Nanotechnology Initiative and Nano-scale Length Metrology T.V. Vorburger (tvtv@nist.gov), Precision Engineering Division R.G. Dixson, J. Fu, N.G. Orji, M.W. Cresswell, R.A. Allen, W.F. Guthrie,

More information

Informatics Framework to Support Integrative

Informatics Framework to Support Integrative Informatics Framework to Support Integrative Science and Engineering in Nanotechnology Stacey Lynn Harper, Ph.D. Environmental and Molecular Toxicology Chemical, Biological and Environmental Engineering

More information

Update of current activities

Update of current activities Update of current activities Zuzana Klöslová ECHA: Dir E & Task force on NMs 25 th - 27 th September, 2013 Chémia 2013, Liptovský Ján, Slovakia *Some slides are courtesy of ECHA 24 September 2013 1 1 Content

More information

CEINT/NIST PROTOCOL REPORTING GUIDELINES FOR THE PREPARATION OF AQUEOUS NANOPARTICLE DISPERSIONS FROM DRY MATERIALS. Ver. 2.0

CEINT/NIST PROTOCOL REPORTING GUIDELINES FOR THE PREPARATION OF AQUEOUS NANOPARTICLE DISPERSIONS FROM DRY MATERIALS. Ver. 2.0 CEINT/NIST PROTOCOL REPORTING GUIDELINES FOR THE PREPARATION OF AQUEOUS NANOPARTICLE DISPERSIONS FROM DRY MATERIALS Ver. 2.0 July 8, 2010 Protocol Contributors: J. S. Taurozzi 1, V. A. Hackley 1, M. R.

More information

NANOMETROLOGY AT CENAM

NANOMETROLOGY AT CENAM 3rd. Trinational Workshop on Standards for Nanotechnology STATUS AND TRENDS OF NANOMETROLOGY AT CENAM Speaker: Rubén J. Lazos-Martínez Centro Nacional de Metrología, México Querétaro, México, February,

More information

The challenge of validating methods for nanoparticle analysis. Robert Koeber, JRC

The challenge of validating methods for nanoparticle analysis. Robert Koeber, JRC The challenge of validating methods for nanoparticle analysis Robert Koeber, JRC 2nd NanoDefine Industry-focused Workshop Frankfurt, October 2017 NanoDefine is funded by the European Community's Seventh

More information

Dr. Heekyung BAE WED.

Dr. Heekyung BAE WED. Dr. Heekyung BAE 2018. 1. 24. WED. 1. Background 2. Objectives and Contents 3. Consortium 4. Progress with Overseas Institutions 1. Background : Needs of Domestic Nano-companies Recently, in the "Nanotechnology

More information

The Danish register for mandatory registration of nanoproducts. Flemming Ingerslev, Section of Chemicals The Danish Environmental Protection Agency

The Danish register for mandatory registration of nanoproducts. Flemming Ingerslev, Section of Chemicals The Danish Environmental Protection Agency The Danish register for mandatory registration of nanoproducts Flemming Ingerslev, Section of Chemicals The Danish Environmental Protection Agency Overview Background and purpose of the registry Preparation

More information

NPL Good Practice Guide and future standards for Graphene

NPL Good Practice Guide and future standards for Graphene NPL Good Practice Guide and future standards for Graphene Charles Clifford Surface Technology Group, National Physical Laboratory, UK charles.clifford@npl.co.uk NPL: Who are we The UK s national standards

More information

TECHNICAL SPECIFICATION

TECHNICAL SPECIFICATION TECHNICAL SPECIFICATION ISO/TS 13278 First edition 2011-11-01 Nanotechnologies Determination of elemental impurities in samples of carbon nanotubes using inductively coupled plasma mass spectrometry Nanotechnologies

More information

Russia region - Overview on chemical control legislation (labelling, MSDS, existing and new substances, etc) and aspects of GHS

Russia region - Overview on chemical control legislation (labelling, MSDS, existing and new substances, etc) and aspects of GHS Russia region - Overview on chemical control legislation (labelling, MSDS, existing and new substances, etc) and aspects of GHS Mrs. Elena Zbitneva, Dr. Dmitry Skobelev CISCENTER e.zbitneva@ciscenter.ru

More information

Nanomechanics Measurements and Standards at NIST

Nanomechanics Measurements and Standards at NIST Nanomechanics Measurements and Standards at NIST Robert F. Cook Deputy Chief, Ceramics Division Leader, Nanomechanical Properties Group robert.cook@nist.gov NIST Mission Promote U.S. innovation and industrial

More information

International Atomic Energy Agency. Department of Nuclear Sciences and Applications. IAEA Environment Laboratories

International Atomic Energy Agency. Department of Nuclear Sciences and Applications. IAEA Environment Laboratories International Atomic Energy Agency Department of Nuclear Sciences and Applications IAEA Environment Laboratories Vienna International Centre, P.O. Box 100, 1400 Vienna, Austria REFERENCE SHEET CERTIFIED

More information

Environmental and IH Considerations in Nanomaterial Production and Use

Environmental and IH Considerations in Nanomaterial Production and Use Environmental and IH Considerations in Nanomaterial Production and Use Elizabeth McMeekin, PE PPG Industries, Inc. emcmeekin@ppg.com Commercialization of NanoMaterials Conference Nov. 12, 2007 NanoMaterials

More information

Monitoring the Aggregation of Particles through Raman Spectroscopy

Monitoring the Aggregation of Particles through Raman Spectroscopy Monitoring the Aggregation of Particles through Raman Spectroscopy Name: Yanxiao Ma Advisor: Dr. Andrew Callender Submission Date: 19 Oct. 2012 Introduction Raman spectroscopy is a spectroscopic technique

More information

ISOTC24/SC4 Particle Sizing by methods other than Sieving

ISOTC24/SC4 Particle Sizing by methods other than Sieving ISOTC24/SC4 Particle Sizing by methods other than Sieving Kevin Powers, Secretary ISOTC24/SC4 (ANSI) Particle Engineering Research Center University of Florida Ph: 352-846-1194 email:kpowers@perc.ufl.edu

More information

CDER Risk Assessment to Evaluate Potential Risks from the Use of Nanomaterials in Drug Products

CDER Risk Assessment to Evaluate Potential Risks from the Use of Nanomaterials in Drug Products CDER Risk Assessment to Evaluate Potential Risks from the Use of Nanomaterials in Drug Products Celia N. Cruz, Ph.D. CDER Nanotechnology Working Group Office of Pharmaceutical Science 1 Disclaimer The

More information

Reference Materials for Trade and Development: Quality and Comparability

Reference Materials for Trade and Development: Quality and Comparability Reference Materials for Trade and Development: Quality and Comparability A. Introduction Scientific measurements are a basic input to decisions made in many areas of human activity. In particular, physical

More information

IEC TC 113 Nanotechnology for electrical and electronic products and systems

IEC TC 113 Nanotechnology for electrical and electronic products and systems IEC TC 113 Nanotechnology for electrical and electronic products and systems Mike Leibowitz TC 113 USNC TAG Secretary mike.leibowitz@nema.org February 28, 2017 ANSI NSP Arlington, VA - Background - Liaisons

More information

Towards a responsible development of Nanomaterials

Towards a responsible development of Nanomaterials Towards a responsible development of Nanomaterials EVONIK Occupational Health Policy Dr. Hans-Jürgen Wiegand, Global Coordination Product Stewardship Evonik Degussa GmbH February 2009 CASG Workshop Responsible

More information

OA03 UNCERTAINTY OF MEASUREMENT IN CHEMICAL TESTING IN ACCORDANCE WITH THE STANDARD SIST EN ISO/IEC Table of contents

OA03 UNCERTAINTY OF MEASUREMENT IN CHEMICAL TESTING IN ACCORDANCE WITH THE STANDARD SIST EN ISO/IEC Table of contents UNCERTAINTY OF MEASUREMENT IN CHEMICAL TESTING IN ACCORDANCE WITH THE STANDARD SIST EN ISO/IEC 17025 Table of contents 1 GENERAL... 2 2 THE STANDARD SIST EN ISO/IEC 17025... 2 3 SA'S POLICY IN IMPLEMENTING

More information

Standards relevant to materials particle characterization

Standards relevant to materials particle characterization Faculty of Mechanical Engineering Institute of Process Engineering and Environmental Technology Research Group Mechanical Process Engineering Standards relevant to materials particle characterization Michael

More information

Essentials of expressing measurement uncertainty

Essentials of expressing measurement uncertainty Essentials of expressing measurement uncertainty This is a brief summary of the method of evaluating and expressing uncertainty in measurement adopted widely by U.S. industry, companies in other countries,

More information

Technical Note A Quantification and NIST Traceability of Micromatter Thin Film Standards for XRF Analysis. Version March 16, 2017

Technical Note A Quantification and NIST Traceability of Micromatter Thin Film Standards for XRF Analysis. Version March 16, 2017 MICROMATTER TECHNOLOGIES INC. #1-8333 130 th Street, Surrey, B.C. V3W 7X4, Canada Phone: +1.604.594.9720 or 1.866.966.2286 Fax: +1.604.594.9726 info@micromatter.com www.micromatter.com Technical Note 2015-01A

More information

ISO INTERNATIONAL STANDARD

ISO INTERNATIONAL STANDARD INTERNATIONAL STANDARD ISO 13318-2 Second edition 2007-09-15 Determination of particle size distribution by centrifugal liquid sedimentation methods Part 2: Photocentrifuge method Détermination de la distribution

More information

Standards for Nanotechnology Workforce Education

Standards for Nanotechnology Workforce Education Standards for Nanotechnology Workforce Education Standards Development Organizations (SDOs) Global International Organization for Standardization International Electrotechnical Commission Regional European

More information

Hazard Banding of Nanomaterials The experience of Solvay

Hazard Banding of Nanomaterials The experience of Solvay Hazard Banding of Nanomaterials The experience of Solvay 26 April 2018 - Brussels J-A Sergent, PhD ERT Toxicological and Environmental Risk Assessment Unit HSE/PRA-PS Tel + 32 2 264 34 04 @: jacques-aurelien.sergent@solvay.com

More information

Occupational Health and Safety Decisions in the face of Nanomaterials Uncertainties. Outline

Occupational Health and Safety Decisions in the face of Nanomaterials Uncertainties. Outline Occupational Health and Safety Decisions in the face of Nanomaterials Uncertainties Greener Nano 2008 Mark McCulloch CIH Hewlett-Packard Outline Pre-Nano (Existing) Situation! Standards, Toxicology, Measurement,

More information

Opportunities and Implications for. the 21st Century

Opportunities and Implications for. the 21st Century Opportunities and Implications for Green Nanotechnology in Industry for the 21st Century Reducing Principles to Practice June 16, 2010 John M. Miller, Ph.D. Dune Sciences, Inc. Nanotechnology CLEAN WATER

More information

Dr. PUJA CHAWLA. * - ASSISTANT PROFESSOR (PHYSICS) JMIT, RADAUR, HARYANA, INDIA.

Dr. PUJA CHAWLA. * - ASSISTANT PROFESSOR (PHYSICS) JMIT, RADAUR, HARYANA, INDIA. Dr. PUJA CHAWLA *E-mail- dr.poojachawla@jmit.ac.in ASSISTANT PROFESSOR (PHYSICS) JMIT, RADAUR, HARYANA, INDIA. NANOTECHNOLOGY & NANOMATERIALS Introduction Nanotechnology & Nanomaterials Synthesis of nanomaterials:

More information

Nanotechnology and Exposure: The Pathway to a Safe and Healthy Environment. Professor Candace Tsai Colorado State University

Nanotechnology and Exposure: The Pathway to a Safe and Healthy Environment. Professor Candace Tsai Colorado State University Nanotechnology and Exposure: The Pathway to a Safe and Healthy Environment Professor Candace Tsai Colorado State University Bogotá, 14-15 FEB 2017 Nanotechnology and Nanomaterials Engineered Nanoparticles-

More information

Nanoparticle Migration and Packaging Lifecycle

Nanoparticle Migration and Packaging Lifecycle ILSI Europe Workshop - Brussels Nanoparticle Migration and Packaging Lifecycle Dr. Qasim Chaudhry The Food and Environment Research Agency York, United Kingdom The views expressed in this presentation

More information

Joint Committee for Traceability in Laboratory Medicine Terminology. R. Wielgosz and S. Maniguet

Joint Committee for Traceability in Laboratory Medicine Terminology. R. Wielgosz and S. Maniguet Joint Committee for Traceability in Laboratory Medicine Terminology R. Wielgosz and S. Maniguet Terminology 1. Understanding the words and phrases we are using 2. Terminology in ISO standards 3. Vocabulary

More information

A basic introduction to reference materials. POPs Strategy

A basic introduction to reference materials. POPs Strategy A basic introduction to reference materials POPs Strategy 2009-2010+ A tutorial 16 September 2009 Angelique Botha R&D metrologist Contents Why do we need reference materials? comparability of results metrological

More information

Global Cooperation on Data Exchange on Hazardous Properties of Chemicals for GHS Classification

Global Cooperation on Data Exchange on Hazardous Properties of Chemicals for GHS Classification Global Cooperation on Data Exchange on Hazardous Properties of Chemicals for GHS Classification Ms. Elena Zhurba CISCenter Russia Federation e.zhurba@ciscenter.ru Mr. Derek D. Swick, MPP Senior Policy

More information

Analytical Methods for Nanomaterials in Food

Analytical Methods for Nanomaterials in Food 1 Analytical Methods for Nanomaterials in Food Hermann Stamm Institute for Health and Consumer Protection Joint Research Centre, Ispra http://www.jrc.ec.europa.eu 2 Nanomaterials in Food Additives Ingredients

More information

European harmonisation of product notification- Status 2014

European harmonisation of product notification- Status 2014 European harmonisation of product notification- Status 2014 Ronald de Groot Dutch National Poisons Information Center University Medical Center Utrecht The Netherlands Poisons Centers Informing the public

More information

METROLOGY AND STANDARDIZATION FOR NANOTECHNOLOGIES

METROLOGY AND STANDARDIZATION FOR NANOTECHNOLOGIES MEROLOGY AND SANDARDIZAION FOR NANOECHNOLOGIES P.A.odua Center for Surface and Vacuum Research (CSVR), Moscow, Moscow Institute of Physics and echnology (MIP) E-mail: fgupnicpv@mail.ru Key words: nanotechnology,

More information

Safe use of nanomaterials Good examples from Finland

Safe use of nanomaterials Good examples from Finland Safe use of nanomaterials Good examples from Finland SweNanoSafe Fokusmöte Nanomaterial i arbetsmiljön, World Trade Center, October 24, 2017; Kai Savolainen, MD, Research Professor, Finnish Institute of

More information

Protecting Workers A NIOSH Nanomaterials Update

Protecting Workers A NIOSH Nanomaterials Update Protecting Workers A NIOSH Nanomaterials Update Alex Lindquist, CSP NREL ESH&Q Programs Group RMS SESHA Annual Mini Conference 10/29/2018 CONTENTS 1 2 3 4 A Quick Intro to Small Things News from NIOSH

More information

Benefits of Regulatory Cooperation for the Management of Chemicals. David Morin Health Canada August, 2018

Benefits of Regulatory Cooperation for the Management of Chemicals. David Morin Health Canada August, 2018 Benefits of Regulatory Cooperation for the Management of Chemicals David Morin Health Canada August, 2018 Regulatory Cooperation Overall Goal: -Support the development of predictable and evidence-based

More information

Nanoparticles in food and non food Recent methods and measurements

Nanoparticles in food and non food Recent methods and measurements Nanoparticles in food and non food Recent methods and measurements Ruud Peters, Stefan Weigel, Hans Marvin and Hans Bouwmeester RIKILT Institute of Food Safety, Wageningen, The Netherlands ruudj.peters@wur.nl,

More information

Key Comparisons, the MRA and CMCs: An International Measurement Infrastructure. Robert Wielgosz. Bureau International des Poids et Mesures

Key Comparisons, the MRA and CMCs: An International Measurement Infrastructure. Robert Wielgosz. Bureau International des Poids et Mesures Key Comparisons, the MRA and CMCs: An International Measurement Infrastructure Robert Wielgosz The task of the BIPM is to ensure world-wide uniformity of measurements and their traceability to the International

More information

Definition and regulation in terms of mechanism of action and intended use

Definition and regulation in terms of mechanism of action and intended use Definition and regulation in terms of mechanism of action and intended use 1 - Nanomaterial-containing medical devices 2 - (Ingestible) medical devices composed of substances IMDRF-3 / 20 March 2013 /

More information

Comparison of the air kerma standards for 137 Cs and 60 Co gamma-ray beams between the IAEA and the NIST. Ronaldo Minniti 1 and Ladislav Czap 2

Comparison of the air kerma standards for 137 Cs and 60 Co gamma-ray beams between the IAEA and the NIST. Ronaldo Minniti 1 and Ladislav Czap 2 Comparison of the air kerma standards for 137 Cs and 60 Co gamma-ray beams between the IAEA and the NIST Ronaldo Minniti 1 and Ladislav Czap 2 1 National Institute of Standards and Technology (NIST), Gaithersburg,

More information

CARBON NANOTUBE ANALYSIS USING THE TSI LIBS DESKTOP ANALYZER

CARBON NANOTUBE ANALYSIS USING THE TSI LIBS DESKTOP ANALYZER CARBON NANOTUBE ANALYSIS USING THE TSI LIBS DESKTOP ANALYZER APPLICATION NOTE LIBS-019 Carbon Nanotubes (CNTs) are used in an ever increasing number of applications, from engineering applications (lighter,

More information

Part 14: Water quality Sampling. Guidance on quality assurance and quality control of environmental water sampling and handling

Part 14: Water quality Sampling. Guidance on quality assurance and quality control of environmental water sampling and handling Provläsningsexemplar / Preview INTERNATIONAL STANDARD ISO 5667-14 Second edition 2014-12-15 Water quality Sampling Part 14: Guidance on quality assurance and quality control of environmental water sampling

More information

Biocidal Products Committee (BPC)

Biocidal Products Committee (BPC) 1(8) Biocidal Products Committee (BPC) Opinion on a request according to Article 75(1)(g) of Regulation (EU) No 528/2012 HeiQ AGS-20 ECHA/BPC/001/2014 Adopted 10 April 2014 Annankatu 18, P.O. Box 400,

More information

Research and Development of Nanoparticle Characterization Methods

Research and Development of Nanoparticle Characterization Methods Research and Development of Nanoparticle Characterization Methods Project Outline This project aims at development of a risk evaluation method based on scientific knowledge for manufactured nanoparticles

More information

Global Intellectual Property Issues for Nanotechs:

Global Intellectual Property Issues for Nanotechs: Global Intellectual Property Issues for Nanotechs: Applications and Standards Chinh H. Pham Greenberg Traurig, LLP (617) 310-6239 phamc@gtlaw.com www.gtlaw.com November 2005 1 GREENBERG TRAURIG, LLP ATTORNEYS

More information

Recent Developments in Standards for Measurement Uncertainty and Traceability (An Overview of ISO and US Uncertainty Activities) CMM Seminar

Recent Developments in Standards for Measurement Uncertainty and Traceability (An Overview of ISO and US Uncertainty Activities) CMM Seminar Recent Developments in Standards for Measurement Uncertainty and Traceability (An Overview of ISO and US Uncertainty Activities) Dr. Steven D. Phillips Precision Engineering Division National Institute

More information

Engineered Nanomaterials and Occupational Health

Engineered Nanomaterials and Occupational Health Engineered Nanomaterials and Occupational Health Andrew D. Maynard Chief Science Advisor Society of Toxicology, National Area Chapter. Novemb er 2nd 2005, Washington DC Woodrow Wilson Center, Project on

More information

International Atomic Energy Agency. Department of Nuclear Sciences and Applications. IAEA Environment Laboratories

International Atomic Energy Agency. Department of Nuclear Sciences and Applications. IAEA Environment Laboratories International Atomic Energy Agency Department of Nuclear Sciences and Applications IAEA Environment Laboratories Vienna International Centre, P.O. Box 100, 1400 Vienna, Austria REFERENCE SHEET CERTIFIED

More information

Safety Guidelines for the Chemistry Professional: Understanding Your Role and Responsibilities

Safety Guidelines for the Chemistry Professional: Understanding Your Role and Responsibilities Safety Guidelines for the Chemistry Professional: Understanding Your Role and Responsibilities Kenneth P. Fivizzani Committee on Chemical Safety/ Division of Chemical Health & Safety August 22, 2017 Introduction

More information

Comparability and Traceability Point of view from a metrological institute

Comparability and Traceability Point of view from a metrological institute Comparability and Traceability Point of view from a metrological institute Ed W.B. de Leer NMi Van Swinden Laboratory Delft, The Netherlands 1 My Discussions in Metrologyland 2 The CCQM in 1996 3 Traceability

More information

NON-FUNCTIONALISED AND FUNCTIONALISED SILICA NANOSPHERES 1. Case metadata

NON-FUNCTIONALISED AND FUNCTIONALISED SILICA NANOSPHERES 1. Case metadata NON-FUNCTIONALISED AND FUNCTIONALISED SILICA NANOSPHERES 1. Case metadata Country/ies of origin: Poland Year of publication by agency: 2011 Sector: NACE-Code: M 72.1 Research and experimental development

More information

The Globally Harmonized System (GHS) for Hazard Classification and Labelling. Development of a Worldwide System for Hazard Communication

The Globally Harmonized System (GHS) for Hazard Classification and Labelling. Development of a Worldwide System for Hazard Communication The Globally Harmonized System (GHS) for Hazard Classification and Labelling Development of a Worldwide System for Hazard Communication What is the GHS? A common and coherent approach to defining and classifying

More information

IS INTERNATIONAL STANDARD. Natural gas - Guidelines to traceability in analysis

IS INTERNATIONAL STANDARD. Natural gas - Guidelines to traceability in analysis INTERNATIONAL STANDARD IS0 14111 First edition 1997-03-15 Natural gas - Guidelines to traceability in analysis Gaz na turel - Lignes directrices pour la tracabilit6 en analyse Reference number IS0 14111

More information

NPL, India activity related to water as per the need of the country

NPL, India activity related to water as per the need of the country NPL, India activity related to water as per the need of the country, Ph.D. (Sr. Scientist) Chemical & Food BND Group Indian Reference Materials (BND) Division CSIR-National Physical Laboratory, New Delhi,

More information

Multi Analyte Custom Grade Solution. Calcium, Iron, Potassium,

Multi Analyte Custom Grade Solution. Calcium, Iron, Potassium, 1.0 ACCREDITATION / REGISTRATION INORGANIC VENTURES is accredited to ISO Guide 34, "General Requirements for the Competence of Reference Material Producers" and ISO/IEC 17025, "General Requirements for

More information

OIML D 28 DOCUMENT. Edition 2004 (E) ORGANISATION INTERNATIONALE INTERNATIONAL ORGANIZATION. Conventional value of the result of weighing in air

OIML D 28 DOCUMENT. Edition 2004 (E) ORGANISATION INTERNATIONALE INTERNATIONAL ORGANIZATION. Conventional value of the result of weighing in air INTERNATIONAL DOCUMENT OIML D 28 Edition 2004 (E) Conventional value of the result of weighing in air Valeur conventionnelle du résultat des pesées dans l'air OIML D 28 Edition 2004 (E) ORGANISATION INTERNATIONALE

More information

Regulatory preparedness workshop Ispra, 5-6 October NANoREG Foresight (System) Platform. Christian Micheletti

Regulatory preparedness workshop Ispra, 5-6 October NANoREG Foresight (System) Platform. Christian Micheletti Regulatory preparedness workshop Ispra, 5-6 October 2017 NANoREG Foresight (System) Platform Christian Micheletti Context: NANoREG project 2 A common European approach to the regulatory testing of Manufactured

More information

Workplace exposure to nanoparticles Literature survey

Workplace exposure to nanoparticles Literature survey Workplace exposure to nanoparticles Literature survey Chemical substances at work: facing up to the challenges Brussels 2-3 March 2009 Joanna Kosk-Bienko Project Manager Work Environment Information Unit

More information

Requirements of a reference measurement procedure and how they relate to a certified reference material for ctni that is fit for purpose

Requirements of a reference measurement procedure and how they relate to a certified reference material for ctni that is fit for purpose Requirements of a reference measurement procedure and how they relate to a certified reference material for ctni that is fit for purpose David M. Bunk, Ph.D. National Institute of Standards and Technology

More information

Development of AFM Platform for Directly Measuring the Nanoparticle-Nanoparticle and Nanoparticle-Cell Interactions

Development of AFM Platform for Directly Measuring the Nanoparticle-Nanoparticle and Nanoparticle-Cell Interactions Development of AFM Platform for Directly Measuring the Nanoparticle-Nanoparticle and Nanoparticle-Cell Interactions Georgios Pyrgiotakis, Christoph Blattmann, Sotiris Pratsinis, Philip Demokritou Harvard

More information

METHODS FOR CERTIFYING MEASUREMENT EQUIPMENT. Scott Crone

METHODS FOR CERTIFYING MEASUREMENT EQUIPMENT. Scott Crone METHODS FOR CERTIFYING MEASUREMENT EQUIPMENT Scott Crone North American Sales Manager AMETEK Calibration Instruments 8600 Somerset Drive Largo, Florida 33773 USA INTRODUCTION Like any other piece of equipment,

More information

STANDARD PROCEDURE: NWSP R2 (15) Polyacrylate Superabsorbent Powders Determination of the Particle Size Distribution by Sieve Fractionation

STANDARD PROCEDURE: NWSP R2 (15) Polyacrylate Superabsorbent Powders Determination of the Particle Size Distribution by Sieve Fractionation 1. Scope STANDARD PROCEDURE: Polyacrylate Superabsorbent Powders Determination of the Particle Size Distribution by Sieve Fractionation This test method specifies a method for measuring particle size distributions

More information

Multi Analyte Custom Grade Solution. Aluminum, Potassium, Magnesium, ANALYTE CERTIFIED VALUE ANALYTE CERTIFIED VALUE

Multi Analyte Custom Grade Solution. Aluminum, Potassium, Magnesium, ANALYTE CERTIFIED VALUE ANALYTE CERTIFIED VALUE 1.0 ACCREDITATION / REGISTRATION INORGANIC VENTURES is accredited to ISO Guide 34, "General Requirements for the Competence of Reference Material Producers" and ISO/IEC 17025, "General Requirements for

More information