Dates 06/ /2014 Ferrara University, Department of Chemical and Pharmaceutical Sciences

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1 E U R O P E A N C U R R I C U L U M V I T A E F O R M A T PERSONAL INFORMATION Name Salvatore Pacifico Telephone salvatore.pacifico@unife.it Nationality Italian Date of birth 29/08/1982 WORK EXPERIENCE Dates 06/2014-to present Modena University, Department of life Sciences Medicinal Chemistry-Synthesis Post-Doc Research Fellowship Drug development for neglected parasitic diseases Dates 06/ /2014 Ferrara University, Department of Chemical and Pharmaceutical Sciences Organic and Medicinal Chemistry-Synthesis Post-Doc Research Fellowship by the Laboratory Network - Tecnopolo Ferrara - LTTA Synthesis of heterodimers MOP / NOP agonists with analgesic activity. (Tutor: Prof. Severo Salvadori). Collaboration with MBV Technologies S.r.l. (Modena, Italy), for the development of new miniplants for raw or refined sugar production. Dates 09/ /2013 Ferrara University, Department of Organic Chemistry Principal Investigator of a project founded by FasTech S.r.l. Collaboration with FasTech S.r.l. for the evaluation of new heterogeneous catalysts in the ammoximation of cyclohexanone to ciclohexanone oxime. Dates 02/ /2011 Ronzoni Institute (Institute for Chemical and Biochemical research)/politecnico di Milano PhD student holder of a Fellowship by NIH Synthesis, characterization and biological evaluation of sulfate trimaltose C-C-linked dimers with heparanase and selectin inibitory activity (Tutors: Dott. Gian Giacomo Torri and Prof. Elena Vismara ) Dates 01/ /2011 Ferrara University, Department of Organic Chemistry

2 Principal Investigator of a project founded by Spinner 2013 (business idea) Synthesis of ionic liquids from carbohydrates resulting from the recycling of biomass Dates 04/ /2009 Ferrara University, Department of Pharmaceutical Sciences Medicinal Chemistry-Synthesis Graduate student Synthesis of 7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Full Agonists for the Potential Treatment of Neuropathic Pain (Tutor: Prof. Pier Giovanni Baraldi) EDUCATION AND TRAINING Name and type of organisation providing education and training Principal subjects/occupational skills covered Title of qualification awarded Dates 21/03/2013 University of Ferrara Organic Synthesis and Reactivity PhD Degree in Organic Chemistry Thesis entitled: Synthesis of Glycopeptides by Thiol-ene/yne Couplings and Study on the Umpolung Reactivity of!-diketones (Tutor: Prof. Olga Bortolini) Date 27/03/2009 Name and type of organisation University of Ferrara providing education and training Principal subjects/occupational Medicinal Chemistry skills covered Title of qualification awarded Master Degree in Medicinal Chemistry Thesis entitled: Design and Synthesis of New 2-Heterocyclyl-imidazo[2,1-i]purin-5-one Derivatives as Potent and Selective Human A3 Adenosine Receptor Antagonists. (Tutor Prof. Pier Giovanni Baraldi) TEACHING ACTIVITY Assistant laboratory technician for the course of Laboratorio di Chimica Farmaceutica Applicata Tutor of a thesis in Chemistry and Pharmaceutical Technology Professor of Analisi Qualitativa del Farmaco for the Pharmaceutical Chemistry and Technology Masters Degree Programme, University of Ferrara PERSONAL SKILLS. Mother tongue Italian Other languages Reading skills Writing skills Verbal skills TECHNICAL SKILLS Organic Synthesis methodologies, Liquid phase synthesis, purification techniques, analytical characterization (IR, NMR, UV, Electrospray mass, MALDI-QTOF MS); Design and synthesis of pharmacologically active compounds; Lead compound optimization; Theoretical knowledge of the main pharmacological assays.

3 OTHER SKILLS Certificate for the free profession of pharmacist

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5 and Anna Zaghi. $%&!"961*1:!"'()*A6!JKLS6!?56!ZV==A O#)3($9*)0#2)(#)3(3*)4%0910/*.*-(/0.)/%090/$&9(N0$(*#)*+)0#&59*4&4$(2&)!) $&$90=90#/%&2) 2&9(30$(3&6) Chiara Ruzza, Anna Rizzi1, Davide Malfacini, Alice Pulga, Salvatore Pacifico, Severo Salvadori, Claudio Trapella, Rainer K. Reinscheid3, Girolamo Calo & Remo Guerrini. 7-12$1!S%+!7%26!=8?:6 0/$(3($") '$52(&') *+) #*/(/&4$(#\*94%0#(#) G]WLMLUX,<^J) 2&9(30$(3&') 1*2(Z&2) (#) 4*'($(*#) [6) S%$.! O?%22'('6! I2'L1! E12P./16! D/1?5'.! N21^%//16! 91/K1&.2%! 71,'_,.6! E12'1! D1$'//1! D%2/%+'6! G1K'5%! E1/01,'('6!W%5%2',1!W%2212'6!E12L!W21(,'+!J'256!G1K'5!O%.2)%!C1$3%2&6! 9%K%2.!91/K15.2'6!O'2./1$.!D1/.A!J'..2)1(',!`!E%5','(1/!D-%$'+&24!5E! ) ) Il sottoscritto acconsente, ai sensi del D.Lgs. 30/06/2003 n.196, al trattamento dei propri dati personali. Il sottoscritto acconsente alla pubblicazione del presente curriculum vitae sul sito dell Università di Ferrara.