PRINCIPALI PUBBLICAZIONI
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1 PRINCIPALI PUBBLICAZIONI M. Benedetti, P. Biscarini, Foresti E., Sabatino P., and R. Kuroda Induced CD on the d-d Transitions of Square Planar MS4 Chromophoric Groups of Ni(II) Complexes with Enantiomeric Dithiophosphate Ligands: (+)589 ( )CD662 Ni[(R,R)bdtp]2 and (-)589 (+)CD662 Ni[(S,S)bdtp]2 Enantiomer 1999, 4, M. Benedetti, P. Biscarini, A. Brillante, and E. Castiglioni Configurational Equilibrium and CD Spectra Under Pressure of Chiral Octahedral Complexes: - and -Cr[(-)(R,R)bdtp]3 Enantiomer 1999, 4, M. Benedetti, P. Biscarini, and A. Brillante The Effect of Pressure on Circular Dichroism Spectra of a Chiral Helicoidal Chromium Complex Physica B 1999, 265, M. Benedetti, P. Biscarini, and A. Brillante The Effect of Pressure on CD Spectra of the Chiral Octahedral Transition Metal Complexes -, - and (, ) Cr[(+)(S)(S)Mebdtp]3 High Pressure Res. 2000, 18, M. Benedetti, J. Malina, J. Kasparova, V. Brabec, G. Natile Chiral Discrimination in Platinum Anticancer Drugs Environ. Health Persp. 2002, 110, M. Benedetti, J. S. Saad, L. G. Marzilli, and G. Natile Chiral Discrimination in the Formation Reaction and at Equilibrium for N,N,N,N'-tetramethyl-1,2-diaminocyclohexane- PtG2 Complexes Dalton Transactions 2003, 5, M. Benedetti, R. Cini, G. Tamasi, and G. Natile Crystal and Molecular Structure and Circular Dichroism of [bis-(guanosine-5 -monophosphate (-1))(N,N,N,N -tetramethylcyclohexyl-1,2-diamine)platinum(ii)] complexes with R,R and S,S configurations of the asymmetric diamine Chem. Eur. J. 2003, 9, P. Biscarini, M. Benedetti, F. Ferranti, R. Kuroda, E. Foresti, P. Sabatino Transfer of Chirality by Dithiophosphate Ligands and Chiral Discrimination in the Stereoselective Formation of Square-Planar Ni(II) Complexes Chirality 2004, 16, Milan Balaz, Andrea E. Holmes, Michele Benedetti, Pamela C. Rodriguez, Nina Berova, Koji Nakanishi, Gloria Proni Synthesis and Circular Dichroism of Tetraarylporphyrin- Oligonucleotide Conjugates J. Am. Chem. Soc. 2005, 127, Milan Balaz, Andrea E. Holmes, Michele Benedetti, Gloria Proni, Nina Berova Porphyrin substituted phosphoramidites: new building blocks for porphyrin oligonucleotide syntheses Bioorg. Med. Chem. 2005, 13, Michele Benedetti, Luigi G. Marzilli, Giovanni Natile Rotamer Stability in cis-[pt(dia)g2] Complexes (dia = Diamine Derivative and G = Guanine Derivative) Mediated by Carrier-
2 Ligand Amine Stereochemistry as Revealed by Circular Dichroism Spectroscopy Chem. Eur. J. 2005, 11, M. Benedetti, F. P. Fanizzi, L. Maresca, G. Natile The Unexpected Reactivity of Zeise s Anion in Strong Basic Medium Discloses New Substitution Patterns at the Platinum Center Chem. Commun. 2006, Paolo Biscarini, Michele Benedetti, Reiko Kuroda, Francesco Ferranti Transfer of Chirality in Complexes with D3 Symmetry: Kinetics of the Formation Reaction of Chiral Tris[O,O - bis(2-methylbutyl)-dithiophosphato]chromium(iii) Complexes ( )-[Cr{(±)-Mebdtp}3], - (+)589- and Λ-( )589-[Cr{(+)-(S)(S)-Mebdtp}3] Eur. J. Inorg. Chem. 2006, 16, Michele Benedetti, Gabriella Tamasi, Renzo Cini, Luigi G. Marzilli, and Giovanni Natile The First Pure HT Rotamer of a Complex with a cis-[metal(nucleotide)2] Unit: A cis- [Pt(amine)2(nucleotide)2] HT Rotamer with Unique Molecular Structural Features Chem. Eur. J. 2007, 13, Vita Mariagrazia Vecchio, Michele Benedetti, Danilo Migoni, Sandra Angelica De Pascali, Antonella Ciccarese, Santo Marsigliante, Francesco Capitelli, Francesco Paolo Fanizzi Highly selective metal mediated ortho-alkylation of phenol. First platinum containing organometallic chromane analogues Dalton Trans. 2007, Michele Benedetti, Cosimo Ducani, Danilo Migoni, Daniela Antonucci, Vita M. Vecchio, Antonella Ciccarese, Alessandro Romano, Tiziano Verri, Giuseppe Ciccarella, and Francesco P. Fanizzi Experimental Evidence That a DNA Polymerase Can Incorporate N7- Platinated Guanines To Give Platinated DNA Angew. Chem. Int. Ed. 2008, 47, Carmen R. Barone, Michele Benedetti, Vita M. Vecchio, Francesco P. Fanizzi, Luciana Maresca and Giovanni Natile New chemistry of olefin complexes of platinum(ii) unravelled by basic conditions: synthesis and properties of elusive cationic species Dalton Trans. 2008, Michele Benedetti, Cosimo Ducani, Danilo Migoni, Daniela Antonucci, Vita M. Vecchio, Alessandro Romano, Tiziano Verri, Francesco P. Fanizzi, Platinum and other heavy metal compounds in cancer chemotherapy, in: A. Bonetti, R. Leone, F. M. Muggia, S. B. Howell (Eds.), Possible Incorporation of Free N7-Platinated Guanines in DNA by DNA Polymerases: Relevance for the Cisplatin Mechanism of Action, Humana Press, New York, 2009, pp Michele Benedetti, Daniela Antonucci, Danilo Migoni, Vita M. Vecchio, Cosimo Ducani, Francesco P. Fanizzi Water-soluble Organometallic Analogues of Oxaliplatin with Cytotoxic and Anticlonogenic Activity ChemMedChem 2010, 5,
3 Jamil S. Saad, Michele Benedetti, Giovanni Natile, Luigi G. Marzilli, Basic Coordination Chemistry Relevant to DNA Adducts Formed by the Cisplatin Anticancer Drug. NMR Studies on Compounds with Sterically Crowded Chiral Ligands Inorg. Chem. 2010, 49, Jamil S. Saad, Michele Benedetti, Giovanni Natile, Luigi G. Marzilli NMR Studies of Models Having the Pt(d(GpG)) 17-Membered Macrocyclic Ring Formed in DNA by Platinum Anticancer Drugs: Pt Complexes with Bulky Chiral Diamine Ligands Inorg. Chem. 2011, 50, Michele Benedetti, Carmen R. Barone, Daniela Antonucci, Vita M. Vecchio, Andrea Ienco, Luciana Maresca, Giovanni Natile, Francesco P. Fanizzi Modulation of properties in analogues of Zeise s anion on changing the ligand trans to ethene. X-Ray crystal structures of trans-[ptcl2(oh)(η 2 -C2H4)] and trans-[ptcl2(η 1 -CH2NO2)(η 2 -C2H4)] Dalton Trans., 2012, 41, Michele Benedetti, Daniela Antonucci, Sandra A. De Pascali, Chiara R. Girelli, Francesco P. Fanizzi Pentacoordinate [PtCl2( 2 -C2H4)(N-N )] complexes with asymmetrically hindered nitrogen donor chelates. Stereospecific synthesis of syn- and anti-[ptcl( 1 - CH2CH2OMe)(Mebpy)] J. Organomet. Chem., 2012, 714, Michele Benedetti, Daniela Antonucci, Sandra A. De Pascali, Giuseppe Ciccarella, Francesco P. Fanizzi Alkyl-vinyl-ethers from alcoholic substrates and the Zeise s salt, via square planar [PtCl(N-N)( 1 -CH2CH2OR)] complexes J. Organomet. Chem., 2012, 714, Chiara Carrisi, Daniela Antonucci, Paola Lunetti, Danilo Migoni, Chiara R. Girelli, Vincenza Dolce, Francesco P. Fanizzi, Michele Benedetti, Loredana Capobianco Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1) J. Inorg. Biochem. 2014, 130, Michele Benedetti, Daniela Antonucci, Chiara R. Girelli, Francesco Capitelli, Francesco P. Fanizzi Reactivity of [PtCl( 2 -C2H4)(N-N)] +, N-N = diimine ligand, with phenol derivatives and first comparison between single crystal X-ray structures of syn- and anti-[pt(n- N)(phenolate)2] rotamers in the solid state Inorg. Chim. Acta 2014, 409, Michele Benedetti, Carmen R. Barone, Chiara R. Girelli, Francesco P. Fanizzi, Giovanni Natile, Luciana Maresca H/D exchange at sp 3 carbons in the coordination sphere of platinum(ii) Dalton Trans., 2014, 43,
4 Michele Benedetti, Chiara R. Girelli, Daniela Antonucci, Sandra A. De Pascali, Francesco P. Fanizzi New method for the synthesis of [PtCl{ 1 -CH2C(O)R}(N-N)] ketonyl derivatives starting from the Zeise s salt Inorg. Chim. Acta 2014, 413, Michele Benedetti, Vincenza Lamacchia, Daniela Antonucci, Paride Papadia, Concetta Pacifico, Giovanni Natile, Francesco P. Fanizzi Insertion of alkynes into Pt-X bonds of square planar [PtX2(N^N)] (X = Cl, Br, I) complexes Dalton Trans., 2014, 43, Michele Benedetti, Chiara R. Girelli, Daniela Antonucci, Francesco P. Fanizzi. [PtCl( 1 - CH2 CH2OR)(N^N)] and [PtCl( 2 -CH2=CH2)(N^N)], N^N = dinitrogen ligand, complexes. Sterical and electronic effects evidenced by NMR analysis J. Organomet. Chem., 2014, 771, Michele Benedetti, Paride Papadia, Chiara R. Girelli, Federica De Castro, Francesco Capitelli, Francesco P. Fanizzi. X-ray structures versus NMR signals in pentacoordinate [PtX2( 2 -CH2=CH2)(Me2phen)] (X = Cl, Br, I), complexes Inorg. Chim. Acta, 2015, 428, Michele Benedetti, Daniela Antonucci, Chiara R. Girelli, Francesco P. Fanizzi " Hindrance, Donor Ability of MenNN Chelates and Overall Stability of Pentacoordinate [PtCl2(η 2 - CH2=CH2)(MenNN)] Complexes as Observed by η 2 -Olefin 1 JPt-C Modulation: An NMR Study Eur. J. Inorg. Chem., 2015, Michele Benedetti, Daniela Antonucci, Federica De Castro, Chiara R. Girelli, Marco Lelli, Norberto Roveri, Francesco P. Fanizzi " Metalated nucleotides chemisorption on hydroxyapatite J. Inorg. Biochem., 2015, 153, Michele Benedetti, Federica De Castro, Daniela Antonucci, Paride Papadia, Francesco Paolo Fanizzi General cooperative effects of single atom ligands on a metal: a 195 Pt NMR chemical shift as a function of coordinated halido ligands ionic radii overall sum Dalton Trans., 2015, 44, Michele Benedetti, Federica De Castro, Alessandro Romano, Danilo Migoni, Barbara Piccinni, Tiziano Verri, Marco Lelli, Norberto Roveri, Francesco P. Fanizzi Adsorption of the cis-[pt(nh3)2(p2o7)] 2 (phosphaplatin) on hydroxyapatite nanocrystals as a smart way to selectively release activated cis-[pt(nh3)2cl2] (cisplatin) in tumor tissues J. Inorg. Biochem., 2016, 157, Michele Benedetti, Alessandro Romano, Federica De Castro, Chiara R. Girelli, Daniela Antonucci, Danilo Migoni, Tiziano Verri, Francesco P. Fanizzi N7-platinated ribonucleotides are not incorporated by RNA polymerases. New perspectives for a rational
5 design of platinum antitumor drugs J. Inorg. Biochem., 2016, doi: /j.jinorgbio Michele Benedetti, Federica De Castro, Francesco P. Fanizzi Square-Planar Pt II versus Octahedral Pt IV Halido Complexes: 195 Pt NMR Explained by a Simple Empirical Approach Eur. J. Inorg. Chem. 2016, Paola Lunetti, Alessandro Romano, Chiara Carrisi, Daniela Antonucci, Tiziano Verri, Giuseppe E. De Benedetto, Vincenza Dolce, Francesco P. Fanizzi, Michele Benedetti Platinated Nucleotides are Substrates for the Human Mitochondrial Deoxynucleotide Carrier (DNC) and DNA Polymerase g: Relevance for the Development of New Platinum- Based Drugs ChemistrySelect 2016, 1,
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