INS TITU TE O F CLINICAL CH E M IS TR Y AND LABO R ATO R Y

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1 INS TITU TE O F CLINICAL CH E M IS TR Y AND LABO R ATO R Y M E D ICINE

FACTS AND FIGURES Ins titute of ClinicalCh e m is try and Laboratory M e dicine Fe rdinand- Saue rbruch - Straße 17475 Gre ifs w

de H om e page : w w w.m e dizin.uni- gre ifs w ald.de /k linch e m / H e ad of ins titute : Univ.- Prof. D r. m e d. M.

2 FACTS AND FIGURES Ins titute of ClinicalCh e m is try and Laboratory M e dicine Fe rdinand- Saue rbruch - Straße Gre ifs w ald Te le ph one : Te le fax: E- M ail: s e k re tariat.k lin.ch e uni- gre ifs w ald.de H om e page : w w w.m e dizin.uni- gre ifs w ald.de /k linch e m / H e ad of ins titute : Univ.- Prof. D r. m e d. M. Nauck Pe rform ance : Th e ins titute pe rform s 1.8 m i lion analys e s pe r ye ar. QUALITY REPORT FOR PATIENTS 2006 UNIVERSITY CLINIC GREIFSW ALD

3 T M ED ICAL CARE SERVICES h e Ins titute of ClinicalCh e m is try and Laboratory M e dicine of th e Unive rs ity Clinic Gre ifs w ald pe rform s laboratory analys e s for a lde partm e nts of th e clinic and for oth e r e xte rnalh os pitals. Th e ins titute is locate d in th e cam pus Saue rbruch s traße. Th e ins titute pe rform s analys e s in ge ne raland s pe cialize d clinicalch e m is try, in h ae m atology, h ae m os tas is and m ole cular biology. Laboratory te s ts w h ich are pe rform e d dire ctly on w ard, for e xam ple blood s ugar de te rm inations or th e de te rm ination of th e blood gas of th e blood of re s pirate d patie nts, are m onitore d by th e ins titute. W e pe rform about 1.8 m i lion analys e s e ach ye ar. Th e ins titute h as a s tate - of- th e art analys e r e q uipm e nt. Th us, w ork ing proce s s e s are h igh ly m e ch anize d. M ore ove r, th e laboratory inform ation s ys te m of th e ins titute can individua ly controlth e analys e r s ys te m s and h e lps our s taff m e m be rs to controlre s ults and to find finaldiagnos e s. Th e arch ive function m ak e s old re ports available at a ltim e s. Th us, th e re ports can be us e d for e m e rge ncy tre atm e nts w h ich could not be planne d in be fore h and. W ith in th e fie ld of clinicalch e m is try e s tablis h e d m e as uring te ch niq ue s are us e d to h e lp to diagnos e dis e as e s of various organ s ys te m s, for e xam ple th e live r or th e k idne ys. Th e proce dure pe rform e d m os t ofte n is th e glucos e de te rm ination, w h ich is im portant for th e diagnos is and for de fining th e corre ct tre atm e nt of patie nts w ith diabe te s m e litus. Th e laboratory autom ation m ak e s it pos s ible to analys e various e le m e nts of th e blood ve ry fas t by us ing s m a lblood s am ple s. Th is is im portant for th e tre atm e nt of s m a lch ildre n and e s pe cia ly ne w borns. Th e s pe cialize d clinicalch e m is try is re s pons ible for th e de te rm ination of h orm one s, w h ich m ay h int on th yroid dis e as e s for e xam ple. W ith in h ae m atology, blood ce ls are counte d w ith th e h e lp of analys e rs and ch a le nging s am ple s are furth e r analys e d by us ing m icros cope s. Blood m orph ology ch ange in cas e s of anae m ia, as a re action to inflam m ation or in cas e s of m alignant dis e as e s. Ce ls of ce re bros pinalfluid and ce ls from oth e r puncture proce dure s are als o counte d and analyze d. UNIVERSITY CLINIC GREIFSW ALD QUALITY REPORT FOR PATIENTS 2006

In h ae m os tas is s o- ca le d globalte s ts are pe rform e d, w h ich h e lp to diagnos e dis orde rs of th e coagulation s ys te m. Ris k s for ble e ding and th rom bos is are applie d.

4 In h ae m os tas is s o- ca le d globalte s ts are pe rform e d, w h ich h e lp to diagnos e dis orde rs of th e coagulation s ys te m. Ris k s for ble e ding and th rom bos is are applie d. Be s ide s th e us e in diagnos tics globalte s ts are als o m andatory for th e m onitoring of anticoagulation th e rapie s. One e xam ple is to de fine th e righ t dos e of a drug w h ich w i l affe ct th e coagulation s ys te m to pre ve nt th e clos ure of ve s s e ls. M ore ove r, w e pe rform various s pe cialize d te s ts to diagnos e dis orde rs of th e coagulation s ys te m at any tim e. Fina ly, th e ins titute applie s m ole cular- biological proce dure s to diagnos e m odifications of th e D NA, w h ich can be us e d to ge t m ore inform ation on h e alth y ris k. QUALITY REPORT FOR PATIENTS 2006 UNIVERSITY CLINIC GREIFSW ALD

5 T SPECIAL AREAS OF M ED ICAL CARE h e m ain tas k of th e ins titute is th e pe rform ance of laboratory analys e s, w h ich as s is t in th e m e dicalcare of s e ve re ly i lpatie nts 24 h ours a day. Th is is e s pe cia ly im portant to patie nts of th e e m e rge ncy unit and patie nts of th e inte ns ive care units. W e are s pe cialize d on th e diagnos is of h e art attack s, coagulation dis orde rs and s e ve re re actions to inflam m ations. Anoth e r s pe ciality is th e diagnos is of m alignant dis e as e s and th e m onitoring of th e dis e as e s progre s s. Als o th e diagnos is of m e tabolic dis orde rs and of diabe te s m e litus plays an im portant role. O QUALITY M ANAGEM ENT ve r th e las t ye ars th e ins titute h as alw ays s ucce s s fu ly tak e n part in various e xte rnalproficie ncy te s ting program s, as pre s cribe d by Ge rm an law. D uring th is proce s s th e laboratory analys e s controlprobe s w ith out k now ing th e e xact conce ntration of th e individualanalyte s of th e probe. Th e re s ults are th e n s e nt to th e initiator of th e e xte rnalproficie ncy te s ting. Are th e re s ults w ith in ce rtain lim its th e ins titute re ce ive s a ce rtificate. W e als o pe rform daily q uality controls to e ns ure th at our re s ults are of ve ry h igh q uality. A lour applie d m e th ods are cons tantly ch e ck e d according to th e ir q uality. W e pay s pe cialatte ntion to pre - analytic proce dure s, as th e m ain s ource s of e rrors can be found on th e w ay from th e patie nt to th e laboratory. M ore ove r, w e active ly w ork for a furth e r de ve lopm e nt of th e le galfram e w ork in coope ration w ith th e Ge rm an s ocialm inis try and th e advis ory board of th e Bunde s - ärzte k am m e r. UNIVERSITY CLINIC GREIFSW ALD QUALITY REPORT FOR PATIENTS 2006

6 T RESEARCH h e ins titute is ve ry e ngage d to furth e r im prove laboratory diagnos tics. Th us, th e ins titute tak e s part in various s tudie s. Es pe cia ly im portant is th e de ve lopm e nt and th e controlof diagnos tic s trate gie s, w h ich are de te rm ine d th rough our coope ration w ith th e com m unity m e dicine and th e SH IP- s tudy. It is als o im portant for us to e s tablis h ne w m e th ods, for e xam ple th e NM R s pe ctros copy, w h ich is us e d to gain ne w ins igh ts into th e m e tabolis m. In our re s e arch data bas e you can alw ays find curre nt re s e arch re ports of our clinic: h ttp://fodb.uni- gre ifs w ald.de /inde x.ph p. QUALITY REPORT FOR PATIENTS 2006 UNIVERSITY CLINIC GREIFSW ALD

A TUTORIAL ON ARTICLE SUBMISSION THROUGH PJR WEBSITE

COMPUTERS IN RADIOLOGY A TUTORIAL ON ARTICLE SUBMISSION THROUGH PJR WEBSITE Muhammad Kashif Mirza (W e b Adm inis trator, PJR w e bs ite ) De partm e ntofradiology, Aga Kh an Unive rs ity H os pital, Karach