RESEARCH PUBLICATIONS 1. Design and synthesis of C3-pyrazole/chalcone linked β-carboline hybrids: Antitopoisomerase I, DNA interactive and apoptosis

Transcription

1 RESEARCH PUBLICATIONS 1. Design and synthesis of C3-pyrazole/chalcone linked β-carboline hybrids: Antitopoisomerase I, DNA interactive and apoptosis inducing anticancer agents; Kamal, A.; Srinivasulu, V.; Nayak, V. L.; Sathish, M.; Shankaraiah, N.; Bagul, C.; Reddy, N. V. S.; Rangaraj, N.; Nagesh, N. ChemMedComm. 2013, (Accepted) 2. Pd-Catalyzed Aryl C-H Activation and Tandem ortho-hydroxylation/alkoxylation of 2-aryl benzimidazoles: Cytotoxicity and DNA-Binding Studies; Kamal, A.; Srinivasulu, V.; Sathish, M.; Tangella, Y.; Nayak, V. L.; Rao M. P. N.; Shankaraiah, N.; Nagesh, N. Asian J. Org. Chem. 2013, (Accepted) 3. Isolation, Synthesis and Biological Evaluation of Phenylpropanoids from the Rhizomes of Alpania galangal; Chourasiya, S. S.; Sreedhar, E.; Babu, K. S.; Shankaraiah, N.; V. Nayak, L. Ramakrishna, S.; Sravani, S.; Rao, M. V. B. Nat. Prod. Comm. 2013, 8, Copper Oxide Nanoparticles Supported on Graphene Oxide-Catalyzed S-Arylation: An Efficient and Ligand-Free Synthesis of Aryl Sulfides; Kamal, A.; Srinivasulu, V.; Murty, J. N. S. R. C.; Shankaraiah, N.; Nagesh, N.; Reddy, T. S.; Rao. A. V. S. Adv. Syn. Cat. 2013, 355, β-[4ʹ-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents; Kamal, A.; Suresh, P.; Ramaiah, M. J.; P.; Reddy, T. S.; Kapavarapu, R. K.; Imthiajali, S.; Reddy, T. L. N.; Pushpavalli, S. N. C. V. L.; Shankaraiah, N. Bhadra, M.-P. Biorg. Med. Chem. 2013, 21, AlCl 3 -NaI Assisted cleavage of polymer-bound esters with concomitant amine coupling and azido-reductive cyclization: Synthesis of pyrrolobenzodiazepine derivatives; Kamal, A.; Prabhakar, S.; Shankaraiah, N.; Markandeya, N.; Srinivasulu, V.; Sathish, M. Tetrahedron Lett. 2013, 54, Water Mediated Heck and Ullmann Couplings by Supported Palladium Nanoparticles: Importance of Surface Polarity of the Carbon Spheres; Kamal, A.; Srinivasulu, V.; Seshadri, B. N.; Markandeya, N.; Alarifi, A.; Shankaraiah. N. Green Chem., 2012, 14, Enantioselective Total Synthesis of (S)-(+)-Lennoxamine Through Asymmetric Hydrogenation Mediated by L- Proline-tetrazole Ruthenium Catalyst; Mirabal-Gallardo, Y.; Piérola, J.; Shankaraiah, N.; Santos, L. S. Tetrahedron Lett. 2012, 53, A One-pot Azido Reductive Tandem Mono-N-Alkylation Employing Dialkylboron Triflates: Online ESI-MS Mechanistic Investigation; Shankaraiah, N.; Markandeya, N.; Srinivasulu, V.; Sreekanth, K.; Reddy, Ch. S.; Santos, L. S.; Kamal, A. J. Org. Chem. 2011, 76, Enantioselective synthesis of asymmetric β-carboline intermediates; Santos, L. S.; Shankaraiah, N.; Espinoza Moraga, M; PCT Int. Appl. 2010, 38pp. CODEN: PIXXD2 WO A (US_Patent) 11. Synthesis and anticancer activity of new chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed alkane spacers; Kamal, A.; Prabhakar, S.; Ramaiah, M. J.; Reddy, P. V.; Reddy, Ch. R.; Mallareddy, A.; Shankaraiah, N.; Reddy, T. L. N.; Pushpavalli, S. N. C. V. L.; Bhadra, M.-P. Eur. J. Med. Chem. 2011, 46, An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-ii inhibition and anticancer activity: Kamal, A.; Kumar, B. A.; Suresh, P.; Shankaraiah, N.; Kumar, M. S. Bioorg. Med. Chem. Lett. 2011, 21, Total syntheses of rutaecarpine and analogues by tandem azido reductive cyclization assisted by microwave irradiation: Kamal, A.; Reddy, M. K.; Reddy, T. S.; Santos, L. S.; Shankaraiah, N. Synlett 2011, Short Total Synthesis of ( )-Lupinine and ( )-Epiquinamide by Double Mit-sunobu reactions: Santos, L. S.; Gallardo, Y.-M.; Shankaraiaha, N.; Simirgiotis, M. J. Synthesis 2011, Asymmetric syntheses of piperidino-benzodiazepines through cation-pool host/guest supramolecular approach and their DNA-binding studies: Markandeya, N.; Shankaraiah, N.; Reddy, Ch. S.; Santos, L. S.; Kamal, A. Tetrahedron: Asymmetry 2010, 21,

2 16. Synthesis of bis-1,2,3-triazolo-bridged unsymmetrical pyrrolobenzodiazepine trimers via click chemistry and their DNA-binding studies: Kamal, A.; Shankaraiah, N.; Reddy, Ch. R.; Prabhakar, S.; Markandeya, N.; Srivastava, H. K.; Sastry, G. N. Tetrahedron, 2010, 66, Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines; Kamal, A.; Sreekanth, K.; Kumar, P. P.; Shankaraiah, N.; Balakishan, G.; Ramaiah, M. J.; Pushpavalli, S.N.C.V.L.; Ray, P.; Bhadra, M. P. Eur. J. Med. Chem. 2010, 45, Short synthesis of noscapine, bicuculline, egenine, capnoidine, and corytensine alkaloids through the addition of 1- siloxy-isobenzofurans to imines: Soriano, M. D. P. C.; Shankaraiah, N.; Santos, L. S. Tetrahedron Lett. 2010, 51, Enantioselective total synthesis of pyrroloquinolone as a potent PDE5 inhibitor; Shankaraiah, N.; Santos, L. S. Tetrahedron Lett. 2009, 50, 2700 (Corrigendum) 20. Novel Supramolecular Palladium Catalyst for the Asymmetric Reduction of Imines in Aqueous Media: Silva, W. A.; Rodrigues, M. T.; Shankaraiah, N.; Ferreira, R. B.; Andrade, C. K. Z.; Pilli, R. A.; Santos, L. S. Org. Lett. 2009, 11, Chemoselective Aromatic Azido Reduction with Concomitant Aliphatic Azide using Al/Gd Triflates-NaI and ESI- MS Mechanistic Studies: Kamal, A.; Markandeya, N.; Shankaraiah, N.; Reddy, Ch. R.; Prabhaker, S.; Reddy, Ch. S. Eberlin, N. M.; Santos, L. S. Chem. Eur. J. 2009, 15, Studies towards the Construction of Quaternary Indolizidines by [2,3]-Sigmatropic Rearrangement Co-catalyzed by Ionic Liquid: Duran-Lara, E. F.; Shankaraiah, N.; Geraldo, D.; Santos, L. S. J. Braz. Chem. Soc., 2009, 20, One-Pot Microwave-Assisted Selective Azido Reduction/Tandem Cyclization in Condensed and Solid-Phase with Nickel Boride: Shankaraiah, N.; Markandeya, N.; Moraga, M.-E.; Kamal, A.; Santos, L. S. Synthesis 2009, Enantioselective total synthesis of pyrroloquinolone as a potent PDE5 inhibitor: Shankaraiah, N.; Santos, L. S. Tetrahedron Lett. 2009, 50, Enantioselective total synthesis of ropivacaine and its analogues: Shankaraiah, N.; Pilli, R. A.; Santos, L. S. Tetrahedron Lett. 2008, 49, Enantioselective total synthesis of (S)-( )-quinolactacin B: Shankaraiah, N.; Silva, W. A.; Andrade, C. K. Z.; Santos, L. S. Tetrahedron Lett. 2008, 49, An efficient selective reduction of aromatic azides to amines employing BF 3.OEt 2 /NaI: Synthesis of pyrrolobenzodiazepines: Kamal, A.; Shankaraiah, N.; Markandeya, N.; Reddy, Ch. S. Synlett 2008, Synthesis of triazolo C8 C8/C2 C8-linked pyrrolobenzodiazepine dimers by employing click chemistry and their DNA-binding affinity: Kamal, A.; Prabhakar, S.; Shankaraiah, N.; Reddy, Ch. R.; Reddy, P. V. Tetrahedron Lett. 2008, 49, Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity: Kamal, A.; Shankaraiah, N.; Prabhakar, S.; Reddy, Ch. R.; Markandeya, N.; Reddy, K. L.; Devaiah, V. Bioorg. Med. Chem. Lett. 2008, 18, A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimmers: Kamal, A.; Shankaraiah, N.; Markandeya, N.; Reddy, K. L.; Reddy, Ch. S. Tetrahedron Lett. 2008, 49, Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing click chemistry: DNA-binding affinity and anticancer activity: Kamal, A.; Shankaraiah, N.; Devaiah, V.; Reddy, K. L.; Juvekar, A.; Sen, S.; Kurian, N.; Zingde. S. Bioorg. Med. Chem. Lett. 2008, 18,

3 32. Design, synthesis and biological activity of A-C8/C-C2-Linked 6-chloropurine-pyrrolobenzodiazepine hybrids as anticancer agents: Kamal, A.; Shankaraiah, N.; Reddy, K. L.; Devaiah, V.; Juvekar, A.; Sen, S. Lett. in Drug. Design&Discovery 2007, 4, Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides: Kamal, A.; Devaiah, V.; Reddy, K. L.; Rajendar, Shetti, R. V. C. R. N. C.; Shankaraiah, N. J. Comb. Chem. 2007, 9, Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones with potential antitubercular activity: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N.; Reddy, G. S. K.; Raghavan, S. J. Comb. Chem. 2007, 9, Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N.; Reddy, D. R. S. Mini-Rev. Med. Chem. 2006, 6, (Review) 36. Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N.; Rao, M. V. Mini-Rev. Med. Chem. 2006, 6, (Review) 37. Solid-phase synthesis of fused [2,1-b]quinazolinone alkaloids: Kamal, A.; Shankaraiah, N.; Devaiah, V.; Reddy, K. L. Tetrahedron Lett. 2006, 47, A polymer-assisted solution-phase strategy for the synthesis of fused [2,1-b]quinazolinones and the preparation of optically active vasicinone: Kamal, A.; Devaiah, V.; Shankaraiah, N.; Reddy, K. L. Synlett 2006, An efficient solid-phase synthesis of biologically important DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine dimers (DSB-120) and their C2-fluorinated analogues: Kamal, A.; Shankaraiah, N.; Devaiah, V.; Reddy, K. L. Tetrahedron Lett. 2006, 47, Selective reduction of aromatic azides in solution/solid-phase and resin cleavage by employing BF 3.OEt 2 /EtSH. Preparation of DC-81: Kamal, A.; Shankaraiah, N.; Reddy, K. L.; Devaiah, V. Tetrahedron Lett. 2006, 47, Conversion of amines to imines employing polymer-supported sulfoxide (PSS) and polymer-supported perruthenate (PSP): Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines: Kamal, A.; Devaiah, V.; Reddy, K. L.; Shankaraiah, N. Adv. Syn. Cat. 2006, 348, Synthesis and biological activity of C-8 fluoroaryl substituted pyrimidine linked-pyrrolobenzodiazepine conjugates: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N.; Kumar, M. S.; Reddy, G. S. K. Lett. in Drug Design&Discovery 2005, 2, A new approach for the solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepines involving reductive cleavage: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N.; Reddy, Y. N. Tetrahedron Lett. 2004, 45, Synthesis of DNA-Interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supported reagents: Preparation of DC-81: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N. Synlett 2004, Facile and efficient solid-phase synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines: Kamal, A.; Reddy, K. L.; Devaiah, V.; Shankaraiah, N. Synlett 2004, POSTER PRESENTATIONS 1. Diversity oriented synthesis of C3-tethered 1, 2, 3-triazolo-β-carbolines via click reaction: A new class of DNA interactive agents and their molecular modelling studies; Chetna, J.; Senwar, K. R.; Ramakrishna, B.; Shankaraiah, N. Second UK-India MedChem Congress 2013 on 22 & 23 rd March 2013 organized by RSC and Indian Institute of Chemical Technology (IICT) Hyderabad. (Selected for Flash Presentation). 2. Design, molecular modelling and synthesis of novel 1,2,3-triazolo-bridged side-armed unsymmetrical naphthalimides and their dimers as DNA intercalators; Gayatri, B. S.; Sharma, P.; Praveen, N.; Shankaraiah, N.

4 Second UK-India MedChem Congress 2013 on 22 & 23 rd March 2013 organized by RSC and Indian Institute of Chemical Technology (IICT) Hyderabad. 3. Molecular design, synthesis, DNA binding affinity and cytotoxicity of tetrahydro-β-carboline-hydantoin hybrids; Chudasama, K. J.; Nekkanti, S.; Jeengar, M. K.; Naidu, V. G. M.; Srinivasulu, V.; Kamal, A.; Shankaraiah, N. Second UK-India MedChem Congress 2013 on 22 & 23 rd March 2013 organized by RSC and Indian Institute of Chemical Technology (IICT) Hyderabad. 4. Design, synthesis, in vitro cytotoxicity and DNA-binding potential of C8-linked 3-cyano-3,3-diphenylpropyl-1- piperazino carbodithioates-pyrrolo[2,1-c][1,4]benzodiazepine derivatives; Sathish, M.; Sreekanth, K.; Srinivasulu, V.; Shankaraiah, N.; Kamal, A. Second UK-India MedChem Congress 2013 on 22 & 23 rd March 2013 organized by RSC and Indian Institute of Chemical Technology (IICT) Hyderabad. 5. Design, Synthesis and DNA-Binding Affinity of Novel C3-Linked Chalcone-β-Carboline Hybrids as Anticancer Agents; Shankaraiah, N.; Siraj, K. P.; Srinivasulu, V.; Vishnuvardhan, M. V. P. S. Ramakrishna, S.; Kamal, A. International Symposium on Challenges in Chemical Biology-2013 on 27 th 29 th January 2013 organized by CSIR- Indian Institute of Chemical Biology (IICB), Kolkata. 6. H 2 O-mediated in-situ azide generated CuAAC reaction from spiro-epoxides by employing β-cyclodextrin as a phase-transfer catalyst: One-pot synthesis of 3-substituted-1,2,3-triazolo-3-hydroxy-indoline-2-ones; Senwar, K. R.; Sharma, P.; Shankaraiah, N. International Symposium on Challenges in Chemical Biology-2013 on 27 th 29 th January 2013 organized by CSIR-Indian Institute of Chemical Biology (IICB), Kolkata. 7. Chalcone and N-Acetyl Pyrazole-Linked β-carboline Derivatives: A New Class of DNA-Intercalating Anticancer Agents; Srinivasulu, V.; Nagesh, N.; Pedapati, S.; Murty, J. N. S. R. C.; Shankaraiah, N.; Kamal, A. National Poster Symposium on ORGANIC/MEDICINAL CHEMISTRY, 15 th December, 2012 organized by Royal Society of Chemistry (London) - Deccan Section, India at CSIR-IICT, Hyderabad. 8. Synthesis and Anticancer Activity of Novel Podophyllotoxin-Thiourea Congeners; Shankaraiah, N.; Babu, S. A.; Reddy, S. T.; Kamal, A. International Symposium on Chemistry and Chemical Biology of Natural Products (CCBNP-2012) on 2-4 August 2012, CSIR-Indian Institute of Chemical Technology, Hyderabad , India 9. Design, Synthesis and DNA-binding ability of C-3 Linked β-carboline-pyrazole Derivatives as novel Anticancer Agents; Srinivasulu, V.; Shankaraiah, N.; Reddy, S. T.; Kamal, A. International Symposium on Chemistry and Chemical Biology of Natural Products (CCBNP-2012) on 2 4 August 2012, CSIR-Indian Institute of Chemical Technology, Hyderabad , India 10. Water Mediated Heck and Ullmann Couplings by Supported Palladium Nanoparticles: Importance of Surface Polarity of the Carbon Spheres: Kamal, A.; Srinivasulu, V.; Seshadri, B. N.; Markandeya, N.; Shankaraiah, N. International Conference on Green Chemistry (ICGC-2011) on 7 9, December 2011, Department of Chemistry School of Chemical Sciences & Pharmacy Central University of Rajasthan, Kishangarh, India 11. Biological Evaluation of Benzimidazole containing 1,2,3-Triazole Residues: Synthesis via Azide-Alkyne Click Reaction: Kamal, A.; Telukutla, S. R.; Suresh, P.; Shankaraiah, N. International Conference on Green Chemistry (ICGC-2011) on 7 9, December 2011, Department of Chemistry School of Chemical Sciences & Pharmacy Central University of Rajasthan, Kishangarh, India 12. Design, Synthesis and Biological Evaluation of β-carboline-chalcone Derivatives as Anticancer Agents; Siraj, K. P.; Srinivasulu, V.; Vishnuvardhan, M. V. P. S.; Ramakrishna, S.; Kamal, A.; Shankaraiah, N. American Association of Pharmaceutical Scientists (AAPS) 2 nd PharmaSci@India on 3 rd & 4 th September 2011 organized by National University of Singapore (NUS) & National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 13. One-pot Aromatic Azidoreductive-N-alkylation Using Dialkylborontriflates as Alkylating Reagents and Online ESI- MS Mechanistic Investigation: Markandeya, N.; Shankaraiah, N.; Reddy, Ch. S. Santos, L. S.; Kamal, A.

5 International Conference on Organic Synthesis and Human Well Being: Emerging Opportunities and Challenges, August 1-4, 2010, Hyderabad, India (Best Poster Award) 14. Diversity Oriented Solid-Phase Synthesis and Cytotoxic Activity of Novel 1,2,3-Triazolo-Chalcone Derivatives by Employing Click Chemistry: Srinivasulu, V.; Sreekanth, K.; Shankaraiah, N.; Juvekar. A. S.; Zingde S. M.; Kamal, A. International Conference on Organic Synthesis and Human Well Being: Emerging Opportunities and Challenges, August 1-4, 2010, Hyderabad, India 15. Design, Synthesis and Anticancer Activity of Novel 4β(1-Phenyl Urea)podophyllotoxin Congeners: Telukutla, S. R.; Suresh, P.; Shankaraiah, N. International Conference on Organic Synthesis and Human Well Being: Emerging Opportunities and Challenges, August 1-4, 2010, Hyderabad, India 16. Solid-phase Synthesis and DNA-binding Ability of a Library of Pyrrolobenzodizepines as Anticancer Agents: Prabhakar, S.; Shankaraiah, N.; Reddy, Ch. R.; Markandeya, N.; Juvekar, A. S.; Zingde, S. M.; Kamal, A. International Conference on Organic Synthesis and Human Well Being: Emerging Opportunities and Challenges, August 1-4, 2010, Hyderabad, India 17. Microwave-assisted syntheses of rutaecarpine and their analogues by employing nickel boride: Reddy, M. K.; Shankaraiah, N.; Kamal, A; Green Chemistry An Innovation to Sustainable Development (GC 2010), Department of Chemistry, Kakatiya University, Warangal , AP, India on 29 th & 30 th March Synthesis of bis-1,2,3-triazolo-bridged unsymmetrical pyrrolobenzodiazepine trimers via click chemistry: Reddy, Ch. R.; Shankaraiah, N.; Prabhakar, S.; Kamal, A; Green Chemistry An Innovation to Sustainable Development (GC 2010), Department of Chemistry, Kakatiya University, Warangal , AP, India on 29 th & 30 th March Enantioselective synthesis of phosphodiestarase-5 inhibitor: Shankaraiah, N.; Santos, L. S; Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS) XIII, Indian Institute of Chemical Technology, Hyderabad, India, November 3 6, Synthesis of triazolo C8 C8/C2 C8-linked pyrrolobenzodiazepine dimers by employing click chemistry and their DNA-binding affinity: Prabhakar, S.; Shankaraiah, N.; Reddy, Ch. R.; Reddy, P. V.; Kamal, A; Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS) XIII, Indian Institute of Chemical Technology, Hyderabad, India, November 3 6, Synthesis of pyrrolo[2,1-b]quinazolinones employing polymer-supported reagents: Devaiah, V.; Reddy, K. L.; Shankaraiah, N.; Kamal. A. Organic Synthesis and Process Chemistry (OSPC), Indian Institute of Chemical Technology, Hyderabad, India, April 1 3, Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones: Devaiah, V.; Shankaraiah, N.; Reddy, K. L.; Kamal, A.; International Conference on Biodiversity and Natural Products Chemistry and Medical Applications, ICOB-4 & ISCNP-24, IUPAC, Delhi University, New Delhi, India, January 26 31, 2004 SCIENTIFIC WORKSHOPS/CONFERENCES 1. Drug Development: Conceptualisation to Commercialisation (D C 2 ), organized in three modules [Module 1: Drug Discovery, Pre clinical & Clinical (30 th, 31 st Aug. & 1 st Sept & Module 2: Medical Writing, Regulatory Affairs & Pharmacovigilance (27 th to 29 th Sept & Module 3: Product Development, Analytical, IPR & Marketing (18 th to 20 th Oct. 2012] by NIPER Hyderabad in association with Novartis India. 2. Short Course on Microwave-Assisted Organic Synthesis 5 th April 2012, conducted by Prof. Oliver Kappe at Taj Deccan, Hyderabad 3. International Conference on Stem Cell and Regenerative Medicine: Research to Business March 22 24, 2012 organized by FABA at Indian School of Business (ISB), Hyderabad 4. Optimizing Opportunities, BioAsia 2012 February 9-11, 2012 organized by FABA in HICC, Hyderabad, Inida

6 5. APA International Congress on Advances in Human Healthcare Systems, Healthcare India 2012 in February 20 23, 2012 organizing by Indian Institute of Technology (IIT) Delhi and Jamia Hamdard (Hamdard University), New Delhi 6. Science Academies Lectures Workshop on Current Trends in Nanoscience & Technology, 23 rd & 24 th December 2011 organized by Department of Chemistry, National Institute of Technology, Warangal, AP, Inida 7. IPC USP Science Standards Symposium from 17 th & 18 th February 2011, Hyderabad, India 8. Summer Workshop on Computer Aided Drug Design & Discovery (CAD 3 ) 2011 organized by NIPER- Hyderabad and VLife Sciences Technologies Pvt. Ltd., Pune from th April Workshop on Drug Discovery: Drug Design, Development, Delivery and Preclinical Studies (D 4 PS)-2010 from 8 th & 9 th October, 12 th & 13 th November and 26 th & 27 th November 2010 organized by NIPER-Hyderabad, Indian Institute of Chemical Technology (IICT) Hyderabad and supported by Novartis Biosciences Hyderabad 10. Summer Workshop on Computer Aided Drug Design and Discovery (CAD 3 )-2010 organized by NIPER- Hyderabad and VLife Sciences Technologies Pvt. Ltd., Pune from 30 th April to 2 nd May Indo-US Conference on New Bioactive Molecules in Pharmaceutical Research Contribution of Natural Products Indo-US CCNP 2006 at Indian Institute of Chemical Technology, Hyderabad on November Joint International Conference on Advances in Organic chemistry and Chemical Biology AOCCB 2006 organized by the Indian Institute of Chemical Technology (CSIR & American Chemical Society), Hyderabad, India, during January 11 12, 2006 INVITED TALKS 1. Design and Synthesis of DNA-Targeted Novel Anticancer Agents; Medicinal Chemistry Conference (MedChem- 2013) on 25 th & 26 th October 2013 organized by Department of Chemistry at Indian Institute of Chemical Technology Madras (IIT-Madras), Chennai, India. 2. Novel Enabling Synthetic Strategies: Sustainable Technologies in Academic Drug Discovery Research; Drug Discovery India 2013 on 27 th & 28 th September 2013 organized by SelectBio, India at Sheraton Hotel, Bangalore. 3. Combinatorial Chemistry and Click Chemistry in the Field of Medicinal Chemistry; National Workshop on Recent Trends in Drug Design on May 8 th to 10 th, 2013 organized by JNTU, Hyderabad, India. 4. Use of Modern Chemical Tools: Emerging in the Investigation of Chemical Research; Orientation Course on Satellite Data Applications in Weather and Climate Change on April 28 th 2013 conducted by JNTU, Hyderabad, India.