Applications of Hypervalent Iodine Reagents in Organic Synthesis Research Publications:

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1 Curriculum vitae Dr. Nandkishor N. Karade Professor Organic Chemistry Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India Contact no.: , Home: (0712) Areas of Research Interest: Applications of Hypervalent Iodine Reagents in Organic Synthesis Research Publications: Total forty (40) international publications in peer reviewed journals Publications after joining RTMN University (July 2009) 1] Ring opening reaction of imidazo[1,2-a]pyridines using (diacetoxyiodo)benzene and NaN 3 : New entry to the synthesis of -iminonitriles Amit H. Kalbandhe, Ashish C. Kawale, and Nandkishor N. Karade European Journal of Organic Chemistry 2017, 10, ] Metal-free new synthesis of 1,3-naphthoxazines via intramolecular cross dehydrogenative-coupling reaction of 1-( -aminoalkyl)-2-naphthols using hypervalent iodine(iii) reagent N. A. Waghmode, A. H. Kalbandhe, P. B. Thorat and Nandkishor N. Karade Tetrahedron Letters 2016, 57, (IF 2.379) 3] Oxidative cleavage of C-2/C-3 bond in isatin using (diacetoxyiodo)benzene: A facile synthesis of carbamates of alkyl anthranilates A. H. Kalbandhe, A. C. Kawale, P. B. Thorat and Nandkishor N. Karade* Synlett 2016, 27, (IF 2.419) 4] Direct metal-free O-arylation of Biginelli 4-aryl-6-methyl-pyrimidine-2(1H)-one derivatives using diaryliodonium salts Prerana B. Thorat, Nitin A. Waghmode and Nandkishor N. Karade Tetrahedron Letters 2014, 55, (IF 2.379) (Total 601 views/downloads during August 2014-July 2015) 1

2 5] 2,4,6-Tris(4-iodophenoxy)-1,3,5-triazine as a new recyclable iodoarene for in situ generation of hypervalent iodine(iii) reagent for α-tosyloxylation of enolizable ketones P. B. Thorat, B. Y. Bhong, A. V. Shelke and Nandkishor N. Karade Tetrahedron Letters 2014, 55, (IF 2.379) (Total 487 views/downloads during April 2014-March 2015) 6] Oxidation 1-amidoalkyl-2-naphthols using (diacetoxyiodo)benzene: Unusual formation of 1-arylnaphtho[1,2-d]isoxazole Amol V. Shelke, Bhagyashree Y. Bhong and Nandkishor N. Karade Synthesis 2014, 46, (IF 2.689) 7] 2,4,6-Tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine as a new recyclable hypervalent iodine(iii) reagent for the chlorination and oxidation reactions Prerana B. Thorat, Bhagyashree Y. Bhong and Nandkishor N. Karade Synlett 2013, 16, (IF 2.419) 8] New synthesis of 3,5-disubstituted-5H-thiazolo-[3,2-α]pyrimidine via ring annulation of 3,4-dihydropyrimidin-2(1H)-thione using alkynyl(aryl)iodonium salts Amol V. Shelke, Bhagyashree Y. Bhong and Nandkishor N. Karade Tetrahedron Letters 2013, 54, (IF 2.379) 9] Nano copper oxide mediated ligand-free C-S cross-coupling and concomitant oxidative aromatization of 4-aryl-3,4-dihydropyrimidin-2(1H)-thione with diaryliodonium salts B. Y. Bhong, A. V. Shelke and Nandkishor N. Karade Tetrahedron Letters 2013, 54, (IF 2.379) (This paper was listed as one of the journal s Top 25 most downloaded papers in February of 2013) 10] Oxidation of 3,4-dihydropyrimidin-2(1H)-thione using (diacetoxyiodo)benzene: Unprecedented formation of substituted 2-(1,4-dihydropyrimidin-2-ylthio)pyrimidine Bhagyashree Y. Bhong, Prerana B. Thorat and Nandkishor N. Karade Tetrahedron Letters 2013, 54, (IF 2.379) 11] Green synthesis of predominant (111) facet CuO nanoparticles: Heterogeneous and recyclable catalyst for N-arylation of indoles Nikhil V. Suramwar, Sanjay R. Thakare, Nandkishor N. Karade, Niren T. Khaty, Journal of Molecular Catalysis A: Chemical 2012, 359, (IF 3.66) (This paper was listed as one of the journal s Top 25 most downloaded papers in July of 2012) 2

3 12] New concise and efficient Synthesis of rubrolides C and E using intramolecular Wittig reaction Nilesh P. Tale, A. V. Shelke, G. B. Tiwari, P. B. Thorat, Nandkishor N. Karade Helvetica Chimica Acta, 2012, 95, (IF 1.43) 13] Dess-Martin periodinane mediated oxidative aromatization of 1,3,5-trisubstituted pyrazolines Nandkishor N. Karade, Nilesh P. Tale, Sumit V. Gampawar Synthetic Communications, 2012, 42, (IF 1.008) 14] Ceric ammonium nitrate as the novel oxidizing agent for the facile synthesis of (dichloroiodo)arenes Nandkishor N. Karade, Nilesh P. Tale, Amol V. Shelke Synthetic Communications, 2012, 42, (IF 1.008) Teaching experience: Teaching experience: More than 18 years (Post graduate M. Sc. Level) Courses taught for M. Sc. (Chemistry Synthetic organic chemistry Reaction mechanism Pericyclic reactions Organic photochemistry Rearrangement reactions NAME reactions Heterocyclic chemistry Oxidation and Reduction P, S, B and Si-reagents Terpenoids and Steroids Alkaloids Peptide/Enzyme chemistry Retro-synthesis Aromatic electrophilic substitution Aromatic nucleophilic substitution Elimination reaction Organometallic chemistry NMR spectroscopy 3

4 Research Projects: Coordinator of UGC SAP DRS-I ( ), Department of Chemistry: Grants sanctioned = Rs crore (Sanctioned Equipment: LCMS) Details of sanctioned Major Research Projects as Principal Investigator: Total Number of Sanctioned Major research projects as Principal Investigator = SIX (three DST, two UGC and one URPS) List of the sanctioned Major Research Projects: 1] Received Sanctioned from DST SERB a research project through Extra Mural Research (EMR) Scheme recently on Applications of hypervalent iodine reagents and iodonium ylides in organic synthesis on February 04, ] Title of the Project: Development of new oxidative methods for the synthesis of heterocyclic compounds Funding agency: RTM Nagpur University (URPS); Amount: 2,43,000/-; Duration: Three year ( ) 3] Title of the Project: Applications of Multi-Component Reactions for the Synthesis of Biologically Important Heterocycles Funding agency: University Grants Commissions, New Delhi Amount: 10,86,800/-, Duration: Three year ( ) 4] Title of the Project: Applications of hypervalent iodine reagents and iodonium ylides in organic synthesis Funding agency: Department of Science and Technology (DST), New Delhi Amount: 37,87,000/-, Duration: Three year ( ) 5] Title of the Project: Chemical transformations induced by hypervalent iodine Funding agency: DST, New Delhi Amount: 8,40,000/-, Duration: Three year ( ) 6] Title of the Project: Development of novel multi-component reactions for the synthesis of heterocyclic compounds Funding agency: University Grants Commissions, New Delhi Amount: 6,67,600/-, Duration: Three year ( ) 4

5 Details of Candidates for Doctoral research Awarded Ph. D. students = six Ph. D. thesis submitted = one Students working for Ph. D. = 04 List of Ph. D. awarded students: 1] Dr. Sumit V. Gampawar (UGC project fellow) Title: New Methods in Organic Synthesis Using Hypervalent Iodine Reagents Date: , SRTM University, Nanded 2] Dr. Nilesh P. Tale, Title: New methods in organic synthesis for functional group transformations and heterocycles synthesis Date: SRTM University, Nanded 3] Dr. Girdharilal B. Tiwari (CSIR senior research fellow) Title: Chemical Transformations Induced by Hypervalent Iodine Reagents Date: , SRTM University, Nanded 4] Dr. Amol V. Shelke (DST project fellow) Title: Applications of hypervalent iodine reagents and iodonium ylides in organic synthesis Date: and ] Dr. Bhagyashri Y. Bhong (UGC project fellow) Title: Applications of hypervalent iodine reagents in organic synthesis Date: and ] Dr. Prerana B. Thorat Title: New Methods for the synthesis of heterocyclic compounds and their biological evaluation Date of Registration: (Viva date: ) List of Ph. D. Students working: Name: Nitin Waghmode Title: Synthesis of Biologically Active Compounds Containing Heteroatom Date of Registration: (Submitted thesis) Name: Amit Kalbandhe Title: Developments of New Methods in Organic Synthesis Using Hypervalent Iodine Reagents, Date of Registration: Name: Ashish Kawale Title: New Applications of Hypervalent Iodine Reagents in Organic Synthesis Date of Registration: Name: Mr. Imran Opai Title: Development of new methods in organic synthesis using hypervalent iodine reagents Registration: January 2017 Name: Mr. Atul A. Jichkar Title: Development of new methods in organic synthesis using hypervalent iodine reagents Registration: January