Jan 16: The Visual System
|
|
- Monica Eaton
- 6 years ago
- Views:
Transcription
1 Geometry of Neuroscience Matilde Marcolli & Doris Tsao Jan 16: The Visual System
2 References for this lecture 1977 Hubel, D. H., Wiesel, T. N., Ferrier lecture 2010 Freiwald, W., Tsao, DY. Functional compartmentalization and viewpoint generalization in the macaque face patch system 2013 Nature Mante, Susillo, Shenoy, Newsome, Context-dependent computation by recurrent dynamics in prefrontal cortex.
3 Santiago Ramon y Cajal (1 May October 1934) Neuron doctrine: The brain is made up of discrete individual cells. Vision is explicable in terms of the firing patterns that emerge from the interactions among many individual neurons. Characterizing functional transformations along anatomically-connected pathways Characterizing population dynamics among large groups of neurons
4 Retina
5
6 Visual processing in the retina Stephen Kuffler David Hubel, Eye, Brain, Vision
7 LGN
8
9
10
11 6 K 5 K 4 3 K 2 K K 1 K 1-2: Magno fast and transient, large RF 2-6: Parvo slow and sustained, small RF K: innervate extrastriate cortex
12 V1 Primary Visual cortex Striate cortex Area 17
13 Hubel & Wiesel, 1959 (HMS)
14
15
16
17
18
19
20
21 Hubel & Wiesel, 1962
22
23
24 Functional Architecture
25 Monkey Human
26 Critical Period
27
28
29 Sparse noise stimulus RF of V1 simple cell Livingstone and Conway, 2003
30 Ohki et al. Nature 2006
31 Features computed by V1 Orientation Color Motion Binocular Disparity
32 What happens to visual information after V1?
33
34
35 What happens to visual information after V2?
36
37
38 Criteria for Cortical Area Topographic map Unique connections Unique cytoarchitecture Unique function
39 Lewis and Van Essen 2000
40
41 Felleman and Van Essen 1991
42
43 Border ownership cell V1 Simple cell (Hubel & Wiesel) V2 Border-ownership cell (von der Heydt)
44
45 What & Where Pathways Vision is knowing what is where by looking David Marr
46 The Ungerleider & Mishkin (1982) Experiment Task 1: Object discrimination study an object select the familiar object (reward) Task 2: Landmark discrimination select foodwell closest to the TOWER temporal lesions impair OBJECT TASK parietal lesions impair LANDMARK TASK
47 The macaque face patch system
48 Pathway for object representation Charles Gross V1 Inferotemporal Cortex (IT) V4 V3 V2 Object identification Image segmentation Discouraged by my inability to understand the frontal lobe I decided to turn my attention to the cortex on the inferior convexity of the temporal lobe Charles Gross, History of Neuroscience autobiography
49 Fusiform face area? Kanwisher, McDermott, & Chun, J. Neurosci, 1997
50 Face-selective regions exist in monkeys
51
52 Localization of face patches occipital frontal PL ML MF posterior AL AF middle anterior AM temporal Faces vs. objects Tsao et al., Nature Neuroscience 2002
53 FMRI response time course from middle face patch ML
54 What is the selectivity of single neurons in each patch?
55 What is the selectivity of single neurons in each patch?
56 What is the selectivity of single neurons in each patch?
57 Single cell from middle face patch
58 Tsao et al., Science, 2006
59 Cell number Face cells are clustered in face patches PL ML MF AL AF AM Tsao et al., Science 2006 Freiwald and Tsao, Science 2010
60 Face patches are strongly and specifically connected to each other PL ML MF AL AF AM Moeller et al. Science 2008 Grimaldi et al., Neuron, in press
61 Probing connectivity of face patches: Microstimulation combined with fmri Moeller et al., Science, 2008 Sebastian Möller
62 Stimulation site on the flatmap posterior ventral x Stimulation site
63 Microstimulation >> Blank posterior ventral x Stimulation site
64 ML projection map overlaps with other face patches posterior ventral x Stimulation site
65 Connections of ML
66 P value Connections within IT cortex largely confined to other face patches posterior ventral PL ML AL x MF AF 10-3 AM Grimaldi et al., Neuron 2016 Injection site in AL, retrograde tracer (Fast Blue) 66
67 Connections within IT cortex largely confined to other face patches posterior ventral PL ML AL x AM MF AF Cells / mm 3 Grimaldi et al., Neuron 2016 Injection site in AL, retrograde tracer (Fast Blue) 67
68 P value Connections within IT cortex largely confined to other face patches posterior ventral PL ML AL x AM MF AF Cells / mm Grimaldi et al., Neuron 2016 Injection site in AL, retrograde tracer (Fast Blue) 68
69 Face patch system
70 Experimental obstacles Huge cortical territory Huge parameter space
71 Experimental obstacles Face patches Faces
72 What are functional properties of cells in each patch?
73 Norm. resp. Cells are selective for the presence and shape of subsets of face features Cell 1 Cell NO HAIR HAIR Freiwald et al., NN 2009
74 Norm. resp. Cells are selective for the presence and appearance of subsets of face features Cell 1 Cell NO IRISES IRISES NO IRISES IRISES Freiwald et al., NN 2009
75 Increasing view invariance from ML/MF to AL to AM ML/MF AM AL
76 Anterior medial face patch (AM) neurons represents face-view invariant identity 0.1s Freiwald and Tsao, 2010
77 Middle face patch (MF/ML) neurons were tuned to head orientation 0.1s Freiwald and Tsao, 2010
78 Middle face patch (MF/ML) neurons were tuned to head orientation 0.1s Freiwald and Tsao, 2010
79 Santiago Ramon y Cajal (1 May October 1934) Neuron doctrine: The brain is made up of discrete individual cells. Vision is explicable in terms of the firing patterns that emerge from the interactions among many individual neurons. Characterizing functional transformations along anatomically-connected pathways Characterizing population dynamics among large groups of neurons
80 Understanding the mechanism for flexible behavior Mante and Newsome 2013
81 Step 1: Compute top 12 PCs of population data D = matrix of eigenvectors Step 2: Demixing (goal: plot neural state in meaningful coordinates) Step 3: Denoise the regression vectors (project onto 12 PCs)
82 Regression coefficients for individual neurons
83 Step 4: Orthogonalize regression vectors (Gramm Schmidt) b 2 Q 2 b 1 Q 1
84
85 So far, not THAT surprising (a fancy way of showing that (1) the monkey can do the task and the choice signal is also represented in PFC, and (2) both color and motion information are represented regardless of context,) What is the underlying mechanism?
86 Recurrent Neural Network x represents activation of neuron, r represents firing rate, J represents recurrent connections, u represents input, c represents offsets, rho represents noise J, b, c are modified through training
87 . Search for fixed points (where x = 0)
88 Red crosses: fixed points (same in both contexts)
89
90 Context-depending integration is explained by different neural dynamics in the two situations!
91 We conclude that the observed complexity and functional roles of single neurons are readily understood in the framework of a dynamical process unfolding at the level of a population.
The functional organization of the visual cortex in primates
The functional organization of the visual cortex in primates Dominated by LGN M-cell input Drosal stream for motion perception & spatial localization V5 LIP/7a V2 V4 IT Ventral stream for object recognition
More information9.01 Introduction to Neuroscience Fall 2007
MIT OpenCourseWare http://ocw.mit.edu 9.01 Introduction to Neuroscience Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms. Complex cell receptive
More informationNonlinear reverse-correlation with synthesized naturalistic noise
Cognitive Science Online, Vol1, pp1 7, 2003 http://cogsci-onlineucsdedu Nonlinear reverse-correlation with synthesized naturalistic noise Hsin-Hao Yu Department of Cognitive Science University of California
More informationFinding a Basis for the Neural State
Finding a Basis for the Neural State Chris Cueva ccueva@stanford.edu I. INTRODUCTION How is information represented in the brain? For example, consider arm movement. Neurons in dorsal premotor cortex (PMd)
More informationNatural Image Statistics
Natural Image Statistics A probabilistic approach to modelling early visual processing in the cortex Dept of Computer Science Early visual processing LGN V1 retina From the eye to the primary visual cortex
More informationVisual Motion Analysis by a Neural Network
Visual Motion Analysis by a Neural Network Kansai University Takatsuki, Osaka 569 1095, Japan E-mail: fukushima@m.ieice.org (Submitted on December 12, 2006) Abstract In the visual systems of mammals, visual
More informationPerception of colour, form, depth and movement; organization of associative visual fields. Seminar Prof Maja Valić
Perception of colour, form, depth and movement; organization of associative visual fields Seminar Prof Maja Valić Perception of colour, form, depth and movement binding problem in the visual system: how
More informationCharles Cadieu, Minjoon Kouh, Anitha Pasupathy, Charles E. Connor, Maximilian Riesenhuber and Tomaso Poggio
Charles Cadieu, Minjoon Kouh, Anitha Pasupathy, Charles E. Connor, Maximilian Riesenhuber and Tomaso Poggio J Neurophysiol 98:733-75, 27. First published Jun 27, 27; doi:.52/jn.265.26 You might find this
More informationHigher Processing of Visual Information: Lecture II --- April 4, 2007 by Mu-ming Poo
Higher Processing of Visual Information: Lecture II April 4, 2007 by Muming Poo 1. Organization of Mammalian Visual Cortices 2. Structure of the Primary Visual Cortex layering, inputs, outputs, cell types
More informationNew Procedures for False Discovery Control
New Procedures for False Discovery Control Christopher R. Genovese Department of Statistics Carnegie Mellon University http://www.stat.cmu.edu/ ~ genovese/ Elisha Merriam Department of Neuroscience University
More informationTopographic organization of areas V3 and V4 and its relation to supra-areal organization of the primate visual system
Visual Neuroscience (2015), 32, e014, 15 pages. Copyright Cambridge University Press, 2015 0952-5238/15 doi:10.1017/s0952523815000115 SPECIAL COLLECTION Controversial Issues in Visual Cortex Mapping REVIEW
More informationSUPPLEMENTARY INFORMATION
Supplementary discussion 1: Most excitatory and suppressive stimuli for model neurons The model allows us to determine, for each model neuron, the set of most excitatory and suppresive features. First,
More informationModeling retinal high and low contrast sensitivity lters. T. Lourens. Abstract
Modeling retinal high and low contrast sensitivity lters T. Lourens Department of Computer Science University of Groningen P.O. Box 800, 9700 AV Groningen, The Netherlands E-mail: tino@cs.rug.nl Abstract
More informationHow Complex Cells Are Made in a Simple Cell Network
How Complex Cells Are Made in a Simple Cell Network Louis Tao Courant Institute, New York University Collaborators: Michael Shelley (Courant, NYU) Robert Shapley (CNS, NYU) David McLaughlin (Courant, NYU)
More informationFundamentals of Computational Neuroscience 2e
Fundamentals of Computational Neuroscience 2e January 1, 2010 Chapter 10: The cognitive brain Hierarchical maps and attentive vision A. Ventral visual pathway B. Layered cortical maps Receptive field size
More informationThe Bayesian Brain. Robert Jacobs Department of Brain & Cognitive Sciences University of Rochester. May 11, 2017
The Bayesian Brain Robert Jacobs Department of Brain & Cognitive Sciences University of Rochester May 11, 2017 Bayesian Brain How do neurons represent the states of the world? How do neurons represent
More informationEmergence of Phase- and Shift-Invariant Features by Decomposition of Natural Images into Independent Feature Subspaces
LETTER Communicated by Bartlett Mel Emergence of Phase- and Shift-Invariant Features by Decomposition of Natural Images into Independent Feature Subspaces Aapo Hyvärinen Patrik Hoyer Helsinki University
More informationÂngelo Cardoso 27 May, Symbolic and Sub-Symbolic Learning Course Instituto Superior Técnico
BIOLOGICALLY INSPIRED COMPUTER MODELS FOR VISUAL RECOGNITION Ângelo Cardoso 27 May, 2010 Symbolic and Sub-Symbolic Learning Course Instituto Superior Técnico Index Human Vision Retinal Ganglion Cells Simple
More informationKrubitzer & Kaas S1 S2
Krubitzer & Kaas S1 S2 V1 V2 A1 MT 30 μm pia white matter Somato- Mean of Motor sensory Frontal Temporal Parietal Visual means Mouse 109.2 ± 6.7 111.9 ±6.9 110.8 ±7.1 110.5 ±6.5 104.7 ±7.2 112.2 ±6.0 109.9
More informationLateral organization & computation
Lateral organization & computation review Population encoding & decoding lateral organization Efficient representations that reduce or exploit redundancy Fixation task 1rst order Retinotopic maps Log-polar
More informationDynamic Shape Synthesis in Posterior Inferotemporal Cortex
Neuron 49, 17 24, January 5, 2006 ª2006 Elsevier Inc. DOI 10.1016/j.neuron.2005.11.026 Dynamic Shape Synthesis in Posterior Inferotemporal Cortex Report Scott L. Brincat 1,2 and Charles E. Connor 1, *
More informationNeuroscience Introduction
Neuroscience Introduction The brain As humans, we can identify galaxies light years away, we can study particles smaller than an atom. But we still haven t unlocked the mystery of the three pounds of matter
More informationVisual motion processing and perceptual decision making
Visual motion processing and perceptual decision making Aziz Hurzook (ahurzook@uwaterloo.ca) Oliver Trujillo (otrujill@uwaterloo.ca) Chris Eliasmith (celiasmith@uwaterloo.ca) Centre for Theoretical Neuroscience,
More informationHierarchy. Will Penny. 24th March Hierarchy. Will Penny. Linear Models. Convergence. Nonlinear Models. References
24th March 2011 Update Hierarchical Model Rao and Ballard (1999) presented a hierarchical model of visual cortex to show how classical and extra-classical Receptive Field (RF) effects could be explained
More informationThe Hebb rule Neurons that fire together wire together.
Unsupervised learning The Hebb rule Neurons that fire together wire together. PCA RF development with PCA Classical Conditioning and Hebbʼs rule Ear A Nose B Tongue When an axon in cell A is near enough
More informationConvolutional neural networks
11-1: Convolutional neural networks Prof. J.C. Kao, UCLA Convolutional neural networks Motivation Biological inspiration Convolution operation Convolutional layer Padding and stride CNN architecture 11-2:
More informationCollecting Aligned Activity & Connectomic Data Example: Mouse Vibrissal Touch Barrel Cortex Exploiting Coherence to Reduce Dimensionality Example: C.
Collecting Aligned Activity & Connectomic Data Example: Mouse Vibrissal Touch Barrel Cortex Exploiting Coherence to Reduce Dimensionality Example: C. elegans Motor Control Sequence Spatially & Temporally
More informationSPIKE TRIGGERED APPROACHES. Odelia Schwartz Computational Neuroscience Course 2017
SPIKE TRIGGERED APPROACHES Odelia Schwartz Computational Neuroscience Course 2017 LINEAR NONLINEAR MODELS Linear Nonlinear o Often constrain to some form of Linear, Nonlinear computations, e.g. visual
More informationSkull-closed Autonomous Development: WWN-7 Dealing with Scales
Skull-closed Autonomous Development: WWN-7 Dealing with Scales Xiaofeng Wu, Qian Guo and Juyang Weng Abstract The Where-What Networks (WWNs) consist of a series of embodiments of a general-purpose brain-inspired
More informationA General Mechanism for Tuning: Gain Control Circuits and Synapses Underlie Tuning of Cortical Neurons
massachusetts institute of technology computer science and artificial intelligence laboratory A General Mechanism for Tuning: Gain Control Circuits and Synapses Underlie Tuning of Cortical Neurons Minjoon
More informationA Multivariate Time-Frequency Based Phase Synchrony Measure for Quantifying Functional Connectivity in the Brain
A Multivariate Time-Frequency Based Phase Synchrony Measure for Quantifying Functional Connectivity in the Brain Dr. Ali Yener Mutlu Department of Electrical and Electronics Engineering, Izmir Katip Celebi
More informationComputer Science and Artificial Intelligence Laboratory Technical Report
Computer Science and Artificial Intelligence Laboratory Technical Report MIT-CSAIL-TR-2013-019 CBCL-313 August 6, 2013 Does invariant recognition predict tuning of neurons in sensory cortex? Tomaso Poggio,
More informationSUPPLEMENTARY INFORMATION
doi:10.1038/nature12742 1. Subjects Two adult male rhesus monkeys, A and F (14 and 12 kg) were trained on a two- alternative, forced- choice, visual discrimination task. Before training, both monkeys were
More information+ + ( + ) = Linear recurrent networks. Simpler, much more amenable to analytic treatment E.g. by choosing
Linear recurrent networks Simpler, much more amenable to analytic treatment E.g. by choosing + ( + ) = Firing rates can be negative Approximates dynamics around fixed point Approximation often reasonable
More informationExercises. Chapter 1. of τ approx that produces the most accurate estimate for this firing pattern.
1 Exercises Chapter 1 1. Generate spike sequences with a constant firing rate r 0 using a Poisson spike generator. Then, add a refractory period to the model by allowing the firing rate r(t) to depend
More informationSustained and transient channels
Sustained and transient channels Chapter 5, pp. 141 164 19.12.2006 Some models of masking are based on two channels with different temporal properties Dual-channel models Evidence for two different channels
More informationAnnouncements: Test4: Wednesday on: week4 material CH5 CH6 & NIA CAPE Evaluations please do them for me!! ask questions...discuss listen learn.
Announcements: Test4: Wednesday on: week4 material CH5 CH6 & NIA CAPE Evaluations please do them for me!! ask questions...discuss listen learn. The Chemical Senses: Olfaction Mary ET Boyle, Ph.D. Department
More informationDiscovering the Human Connectome
Networks and Complex Systems 2012 Discovering the Human Connectome Olaf Sporns Department of Psychological and Brain Sciences Indiana University, Bloomington, IN 47405 http://www.indiana.edu/~cortex, osporns@indiana.edu
More informationLimulus. The Neural Code. Response of Visual Neurons 9/21/2011
Crab cam (Barlow et al., 2001) self inhibition recurrent inhibition lateral inhibition - L16. Neural processing in Linear Systems: Temporal and Spatial Filtering C. D. Hopkins Sept. 21, 2011 The Neural
More informationSupplementary Information. Brain networks involved in tactile speed classification of moving dot patterns: the. effects of speed and dot periodicity
Supplementary Information Brain networks involved in tactile speed classification of moving dot patterns: the effects of speed and dot periodicity Jiajia Yang, Ryo Kitada *, Takanori Kochiyama, Yinghua
More informationSUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION 1. Supplementary Tables 2. Supplementary Figures 1/12 Supplementary tables TABLE S1 Response to Expected Value: Anatomical locations of regions correlating with the expected value
More informationTilt-aftereffect and adaptation of V1 neurons
Tilt-aftereffect and adaptation of V1 neurons Dezhe Jin Department of Physics The Pennsylvania State University Outline The tilt aftereffect (TAE) Classical model of neural basis of TAE Neural data on
More informationNeural Networks 1 Synchronization in Spiking Neural Networks
CS 790R Seminar Modeling & Simulation Neural Networks 1 Synchronization in Spiking Neural Networks René Doursat Department of Computer Science & Engineering University of Nevada, Reno Spring 2006 Synchronization
More informationThe Temporal Dynamics of Cortical Normalization Models of Decision-making
Letters in Biomathematics An International Journal Volume I, issue 2 (24) http://www.lettersinbiomath.org Research Article The Temporal Dynamics of Cortical Normalization Models of Decision-making Thomas
More informationRegML 2018 Class 8 Deep learning
RegML 2018 Class 8 Deep learning Lorenzo Rosasco UNIGE-MIT-IIT June 18, 2018 Supervised vs unsupervised learning? So far we have been thinking of learning schemes made in two steps f(x) = w, Φ(x) F, x
More informationNew Approaches to False Discovery Control
New Approaches to False Discovery Control Christopher R. Genovese Department of Statistics Carnegie Mellon University http://www.stat.cmu.edu/ ~ genovese/ Larry Wasserman Department of Statistics Carnegie
More informationLayer 3 patchy recurrent excitatory connections may determine the spatial organization of sustained activity in the primate prefrontal cortex
Neurocomputing 32}33 (2000) 391}400 Layer 3 patchy recurrent excitatory connections may determine the spatial organization of sustained activity in the primate prefrontal cortex Boris S. Gutkin *, G. Bard
More informationNeuroinformatics. Marcus Kaiser. Week 10: Cortical maps and competitive population coding (textbook chapter 7)!
0 Neuroinformatics Marcus Kaiser Week 10: Cortical maps and competitive population coding (textbook chapter 7)! Outline Topographic maps Self-organizing maps Willshaw & von der Malsburg Kohonen Dynamic
More informationCorrelations and neural information coding Shlens et al. 09
Correlations and neural information coding Shlens et al. 09 Joel Zylberberg www.jzlab.org The neural code is not one-to-one ρ = 0.52 ρ = 0.80 d 3s [Max Turner, UW] b # of trials trial 1!! trial 2!!.!.!.
More information1/12/2017. Computational neuroscience. Neurotechnology.
Computational neuroscience Neurotechnology https://devblogs.nvidia.com/parallelforall/deep-learning-nutshell-core-concepts/ 1 Neurotechnology http://www.lce.hut.fi/research/cogntech/neurophysiology Recording
More informationSemi-supervised subspace analysis of human functional magnetic resonance imaging data
Max Planck Institut für biologische Kybernetik Max Planck Institute for Biological Cybernetics Technical Report No. 185 Semi-supervised subspace analysis of human functional magnetic resonance imaging
More informationVisual System. Anatomy of the Visual System. Advanced article
Stephen D Van Hooser, Brandeis University, Waltham, Massachusetts, USA Sacha B Nelson, Brandeis University, Waltham, Massachusetts, USA Humans and many other animals obtain much of their information about
More informationStructure and function of parallel pathways in the primate early visual system
J Physiol 566.1 (2005) pp 13 19 13 SYMPOSIUM REPORT Structure and function of parallel pathways in the primate early visual system Edward M. Callaway Systems Neurobiology Laboratories, The Salk Institute
More informationLecture 6: Non-Cortical Visual Pathways MCP 9.013/7.68, 03
Lecture 6: Non-Cortical Visual Pathways MCP 9.013/7.68, 03 Roger W. Sperry The problem of central nervous reorganization after nerve regeneration and muscle transposition. R.W. Sperry. Quart. Rev. Biol.
More informationNCNC FAU. Modeling the Network Architecture of the Human Brain
NCNC 2010 - FAU Modeling the Network Architecture of the Human Brain Olaf Sporns Department of Psychological and Brain Sciences Indiana University, Bloomington, IN 47405 http://www.indiana.edu/~cortex,
More informationResolving the organization of the third tier visual cortex in primates: A hypothesis-based approach
Visual Neuroscience (2015), 32, e010, 26 pages. Copyright Cambridge University Press, 2015. The online version of this article is published within an Open Access environment subject to the conditions of
More informationHierarchical Clustering Identifies Hub Nodes in a Model of Resting-State Brain Activity
WCCI 22 IEEE World Congress on Computational Intelligence June, -5, 22 - Brisbane, Australia IJCNN Hierarchical Clustering Identifies Hub Nodes in a Model of Resting-State Brain Activity Mark Wildie and
More informationClicker Question. Discussion Question
Connectomics Networks and Graph Theory A network is a set of nodes connected by edges The field of graph theory has developed a number of measures to analyze networks Mean shortest path length: the average
More informationCongruent and Opposite Neurons: Sisters for Multisensory Integration and Segregation
Congruent and Opposite Neurons: Sisters for Multisensory Integration and Segregation Wen-Hao Zhang 1,2, He Wang 1, K. Y. Michael Wong 1, Si Wu 2 wenhaoz@ust.hk, hwangaa@connect.ust.hk, phkywong@ust.hk,
More information!) + log(t) # n i. The last two terms on the right hand side (RHS) are clearly independent of θ and can be
Supplementary Materials General case: computing log likelihood We first describe the general case of computing the log likelihood of a sensory parameter θ that is encoded by the activity of neurons. Each
More informationMarr's Theory of the Hippocampus: Part I
Marr's Theory of the Hippocampus: Part I Computational Models of Neural Systems Lecture 3.3 David S. Touretzky October, 2015 David Marr: 1945-1980 10/05/15 Computational Models of Neural Systems 2 Marr
More informationThe role of ephrins and structured retinal activity in the development of visual map topography
The role of ephrins and structured retinal activity in the development of visual map topography David Feldheim, UC Santa Cruz KITP Brain08 March 21, 2008 Topographic map development in the mouse visual
More informationNature Neuroscience: doi: /nn Supplementary Figure 1. Expression of GCaMP6s in LGN and their axons in V1.
Supplementary Figure 1 Expression of GCaMP6s in LGN and their axons in V1. (a, b) Coronal section of LGN and V1 expressing GCaMP6s. a Coronal slice (bregma -2.3 mm) including thalamus confirmed that GCaMP6s
More informationSub-Riemannian geometry in models of the visual cortex
Sub-Riemannian geometry in models of the visual cortex Scott Pauls Department of Mathematics Dartmouth College 4 th Symposium on Analysis and PDE Purdue, May 27, 2009 Mathematical structure in the visual
More informationNormative Theory of Visual Receptive Fields
Normative Theory of Visual Receptive Fields Tony Lindeberg Computational Brain Science Lab, Department of Computational Science and Technology, KTH Royal Institute of Technology, SE-00 44 Stockholm, Sweden.
More informationStatistical models for neural encoding
Statistical models for neural encoding Part 1: discrete-time models Liam Paninski Gatsby Computational Neuroscience Unit University College London http://www.gatsby.ucl.ac.uk/ liam liam@gatsby.ucl.ac.uk
More informationExperimental design of fmri studies & Resting-State fmri
Methods & Models for fmri Analysis 2016 Experimental design of fmri studies & Resting-State fmri Sandra Iglesias With many thanks for slides & images to: Klaas Enno Stephan, FIL Methods group, Christian
More informationRealistic Modeling of Simple and Complex Cell Tuning in the HMAX Model, and Implications for Invariant Object Recognition in Cortex
massachusetts institute of technology computer science and artificial intelligence laboratory Realistic Modeling of Simple and Complex Cell Tuning in the HMAX Model, and Implications for Invariant Object
More informationFunctional form of motion priors in human motion perception
Functional form of motion priors in human motion perception Hongjing Lu,2 hongjing@ucla.edu Alan L. F. Lee alanlee@ucla.edu Tungyou Lin 3 tungyoul@math.ucla.edu Luminita Vese 3 lvese@math.ucla.edu Alan
More informationCompetitive Learning for Deep Temporal Networks
Competitive Learning for Deep Temporal Networks Robert Gens Computer Science and Engineering University of Washington Seattle, WA 98195 rcg@cs.washington.edu Pedro Domingos Computer Science and Engineering
More informationLinking connectivity, dynamics and computations in low-rank recurrent neural networks
Linking connectivity, dynamics and computations in low-rank recurrent neural networks Francesca Mastrogiuseppe 1,2, Srdjan Ostojic 1 * 1 Laboratoire de Neurosciences Cognitives, INSERM U960 and 2 Laboratoire
More informationNew Machine Learning Methods for Neuroimaging
New Machine Learning Methods for Neuroimaging Gatsby Computational Neuroscience Unit University College London, UK Dept of Computer Science University of Helsinki, Finland Outline Resting-state networks
More informationExperimental design of fmri studies
Methods & Models for fmri Analysis 2017 Experimental design of fmri studies Sara Tomiello With many thanks for slides & images to: Sandra Iglesias, Klaas Enno Stephan, FIL Methods group, Christian Ruff
More informationA Biologically-Inspired Model for Recognition of Overlapped Patterns
A Biologically-Inspired Model for Recognition of Overlapped Patterns Mohammad Saifullah Department of Computer and Information Science Linkoping University, Sweden Mohammad.saifullah@liu.se Abstract. In
More informationSpatial Representations in the Parietal Cortex May Use Basis Functions
Spatial Representations in the Parietal Cortex May Use Basis Functions Alexandre Pouget alex@salk.edu Terrence J. Sejnowski terry@salk.edu Howard Hughes Medical Institute The Salk Institute La Jolla, CA
More informationNext: Before we talk about topographic organization, we will review some species differences, and take a look at lamination in the midbrain tectum.
Next: Before we talk about topographic organization, we will review some species differences, and take a look at lamination in the midbrain tectum. 1 Midbrain: Species comparisons An exercise in topology:
More informationPosition Variance, Recurrence and Perceptual Learning
Position Variance, Recurrence and Perceptual Learning Zhaoping Li Peter Dayan Gatsby Computational Neuroscience Unit 7 Queen Square, London, England, WCN 3AR. zhaoping@gatsby.ucl.ac.uk dayan@gatsby.ucl.ac.uk
More informationVentral Visual Stream and Deep Networks
Ma191b Winter 2017 Geometry of Neuroscience References for this lecture: Tomaso A. Poggio and Fabio Anselmi, Visual Cortex and Deep Networks, MIT Press, 2016 F. Cucker, S. Smale, On the mathematical foundations
More informationLeo Kadanoff and 2d XY Models with Symmetry-Breaking Fields. renormalization group study of higher order gradients, cosines and vortices
Leo Kadanoff and d XY Models with Symmetry-Breaking Fields renormalization group study of higher order gradients, cosines and vortices Leo Kadanoff and Random Matrix Theory Non-Hermitian Localization in
More informationA Neurocomputational Model of Smooth Pursuit Control to Interact with the Real World
A Neurocomputational Model of Smooth Pursuit Control to Interact with the Real World by Seyed Omid Sadat Rezai A thesis presented to the University of Waterloo in fulfillment of the thesis requirement
More informationBig Data and the Brain G A L L A NT L A B
Big Data and the Brain MICHAEL O L IVER G A L L A NT L A B UC BERKELEY The brain is gigantic The human brain has ~100 billion neurons connected by ~100 trillion synapses Multiple levels of organization
More informationCHARACTERIZATION OF NONLINEAR NEURON RESPONSES
CHARACTERIZATION OF NONLINEAR NEURON RESPONSES Matt Whiteway whit8022@umd.edu Dr. Daniel A. Butts dab@umd.edu Neuroscience and Cognitive Science (NACS) Applied Mathematics and Scientific Computation (AMSC)
More informationDecision-making and Weber s law: a neurophysiological model
European Journal of Neuroscience, Vol. 24, pp. 901 916, 2006 doi:10.1111/j.14-9568.2006.04940.x Decision-making and Weber s law: a neurophysiological model Gustavo Deco 1 and Edmund T. Rolls 2 1 Institucio
More informationCognitive Prosem. December 1, 2008
Cognitive Prosem December 1, 2008 Spatial Representation What does it mean to represent spatial information? What are the characteristics of human spatial representations? Reference Frames/Systems Distortions
More informationModelling temporal structure (in noise and signal)
Modelling temporal structure (in noise and signal) Mark Woolrich, Christian Beckmann*, Salima Makni & Steve Smith FMRIB, Oxford *Imperial/FMRIB temporal noise: modelling temporal autocorrelation temporal
More informationStructured hierarchical models for neurons in the early visual system
Structured hierarchical models for neurons in the early visual system by Brett Vintch A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy Center for
More informationSlow Feature Analysis on Retinal Waves Leads to V1 Complex Cells
Slow Feature Analysis on Retinal Waves Leads to V1 Complex Cells Sven Dähne 1,2,3 *, Niko Wilbert 2,3, Laurenz Wiskott 2,3,4 1 Machine Learning Group, Department of Computer Science, Berlin Institute of
More informationDeep learning in the visual cortex
Deep learning in the visual cortex Thomas Serre Brown University. Fundamentals of primate vision. Computational mechanisms of rapid recognition and feedforward processing. Beyond feedforward processing:
More informationSynchronization in Spiking Neural Networks
CS 790R Seminar Modeling & Simulation Synchronization in Spiking Neural Networks ~ Lecture 8 ~ René Doursat Department of Computer Science & Engineering University of Nevada, Reno Spring 2005 Synchronization
More informationA quantitative theory of neural computation
Biol Cybern (2006) 95:205 211 DOI 10.1007/s00422-006-0079-3 ORIGINAL PAPER A quantitative theory of neural computation Leslie G. Valiant Received: 16 September 2005 / Accepted: 25 April 2006 / Published
More informationNeural Networks. Henrik I. Christensen. Computer Science and Engineering University of California, San Diego
Neural Networks Henrik I. Christensen Computer Science and Engineering University of California, San Diego http://www.hichristensen.net Henrik I. Christensen (UCSD) Neural Networks 1 / 39 Introduction
More informationSpatial Vision: Primary Visual Cortex (Chapter 3, part 1)
Spatial Vision: Primary Visual Cortex (Chapter 3, part 1) Lecture 6 Jonathan Pillow Sensation & Perception (PSY 345 / NEU 325) Princeton University, Spring 2015 1 Chapter 2 remnants 2 Receptive field:
More informationDoing Cosmology with Balls and Envelopes
Doing Cosmology with Balls and Envelopes Christopher R. Genovese Department of Statistics Carnegie Mellon University http://www.stat.cmu.edu/ ~ genovese/ Larry Wasserman Department of Statistics Carnegie
More informationEffects of Betaxolol on Hodgkin-Huxley Model of Tiger Salamander Retinal Ganglion Cell
Effects of Betaxolol on Hodgkin-Huxley Model of Tiger Salamander Retinal Ganglion Cell 1. Abstract Matthew Dunlevie Clement Lee Indrani Mikkilineni mdunlevi@ucsd.edu cll008@ucsd.edu imikkili@ucsd.edu Isolated
More informationExperimental design of fmri studies
Experimental design of fmri studies Sandra Iglesias With many thanks for slides & images to: Klaas Enno Stephan, FIL Methods group, Christian Ruff SPM Course 2015 Overview of SPM Image time-series Kernel
More informationGraph theory for complex Networks-I
Int. J. of Mathematical Sciences and Applications, Vol. 1, No. 3, September 2011 Copyright Mind Reader Publications www.journalshub.com Graph theory for complex Networks-I V.Yegnanarayanan 1 and G.K.Umamaheswari
More informationGlobal Layout Optimization of Olfactory Cortex and of Amygdala of Rat
UMIACS-TR-2007-14 CS-TR-4861 Global Layout Optimization of Olfactory Cortex and of Amygdala of Rat Raul Rodriguez-Esteban and Christopher Cherniak June 2005 Committee for Philosophy and the Sciences, Department
More informationClass Learning Data Representations: beyond DeepLearning: the Magic Theory. Tomaso Poggio. Thursday, December 5, 13
Class 24-26 Learning Data Representations: beyond DeepLearning: the Magic Theory Tomaso Poggio Connection with the topic of learning theory 2 Notices of the American Mathematical Society (AMS), Vol. 50,
More informationInformation maximization in a network of linear neurons
Information maximization in a network of linear neurons Holger Arnold May 30, 005 1 Introduction It is known since the work of Hubel and Wiesel [3], that many cells in the early visual areas of mammals
More informationExperimental design of fmri studies
Experimental design of fmri studies Sandra Iglesias Translational Neuromodeling Unit University of Zurich & ETH Zurich With many thanks for slides & images to: Klaas Enno Stephan, FIL Methods group, Christian
More information