FASEB SRC Small GTPases in Membrane Processes: Trafficking, Autophagy and Disease. September 23-28, 2018 National Conference Center, Leesburg VA

Transcription

1 FASEB SRC Small GTPases in Membrane Processes: Trafficking, Autophagy and Disease September 23-28, 2018 National Conference Center, Leesburg VA Co-Organizers: Nava Segev University of Illinois at Chicago Chicago, IL 60607, USA Marino Zerial Max Planck Institute of Molecular Cell Biology and Genetics, MPI-CBG Dresden, Germany Program

2 Sunday, September 23, :00PM 9:00PM 5:00PM 6:00PM 7:00PM 7:50PM Conference Registration FASEB Opening Reception Session Chair: Nava Segev Keynote Lecture Dafna Bar-Sagi, NYUMC (USA) Ras GTPases in trafficking and signal regulation 7:50PM 9:20PM Posters Overview: Two-minute presentations Monday, September 24, :30AM 9:00AM - 9:00AM 9:15AM Session 1 9:15AM 12:30PM 9:15AM 9:45AM 9:45AM 10:15AM Welcome from FASEB Small GTPases in Trafficking I Session Chair: Richard Kahn, Emory University (USA) Cathy Jackson, Université Paris (FR) Arf exchange factors Elizabeth Sztul, University of Alabama at Birmingham (USA) Mathematical modelling of regulation of transport by Arf GEFs 10:15AM 10:30AM Short Talk 1 10:30AM 11:00AM 11:00AM 11:30AM 11:30AM 12:00AM Jim Casanova, University of Virginia (USA) Control of cell motility by Arf GTPases Richard Kahn, Emory University (USA) Arfs/Arls and friends 12:00AM 12:15PM Short Talk 2 12:15PM 12:30PM Short Talk 3 12:30PM 1:30PM 1:30PM 2:30PM 2:30PM 4:00PM Workshop: Career Development Free Time

3 4:00PM 6:00PM Session 2 7:00PM 9:45PM Poster Session 1 (odd numbered posters) Small GTPases in Trafficking II Session Chair: Jennifer Stow, IMB Brisbane (AU) Harald Stenmark, Radium Hospital Oslo (NO) Function of Rab GTPases in macropinocytosis Juan Bonifacino, NICHD, NIH (USA) Small GTPases in the endosomal-lysosomal System 8:00PM 8:15PM Short Talk 4 8:15PM 8:45PM 8:45PM 9:15PM TBA 2 9:15PM 9:45PM Jennifer Stow, IMB Brisbane (AU) Small GTPases in inflammation and cancer Tuesday, September 25, :30AM 9:00AM Session 3 9:00AM 12:30PM 10:00AM 10:30AM 10:30AM 11:00AM Small GTPases in Autophagy Session Chair: Sharon Tooze, Francis Crick Institute (UK) Nava Segev, University of Illinois (USA) Ypt GTPases in autophagy Peter McPherson, McGill University (CA) Rabs DENNs and autophagy Sharon Tooze, Francis Crick Institute (UK) Regulation and role of the ER-Golgi contact sites and Group Photo 11:00AM 11:15AM Short Talk 5 11:15AM 11:30AM Short Talk 6 11:30AM 12:00PM 12:00PM 12:30PM 12:30PM 1:30PM 1:30PM 2:30PM Kun-Liang Guan, UCSD (USA) Rags and autophagy Roberto Zoncu, Berkeley (US) Rags and the lysosome Workshop: Meet the Editors:

4 Challenges of the Peer Review Evaluation 2:30PM 4:00PM 4:00PM 6:00PM Session 4 7:00PM 10:00PM Free Time Poster Session 2 (even numbered posters) Small GTPases in Disease and Host-Pathogen Interactions Session Chair: Kim Orth, UT Southwestern Medical Center (USA) Kim Orth, UT Southwestern Medical Center (USA) GTPase regulation in eukaryotic host and bacterial pathogen interactions Stefania Spanò, University of Aberdeen (UK) Rab GTPases and the mechanisms of Salmonella Typhi pathogenesis 8:00PM 8:15PM Short Talk 7 8:15PM 8:45PM 8:45PM 9:00PM Short Talk 8 9:00PM 9:30PM 9:30PM 10:00PM Anne-Marie Krachler, UT Houston (USA) Adhesion through small GTPases Peng Li, Tsighua University, Beiging (CN) Rab GTPases and lipid droplets and liver metabolism Wednesday, September 26, :30AM 9:00AM Session 5 9:00AM 12:15PM Structure and Regulation of Small GTPases Session Chair: Roger Goody, MPI of Molecular Physiology, Dortmund (DE) Jacqueline Cherfils, ENS Paris Saclay (FR) Allosteric regulation of Arf and co-factors on membranes David Lambright, UMASS Medical School (USA) Rab and Arf regulatory mechanisms in normal and disease conditions 10:00AM 10:15AM Short Talk 9 10:15AM 10:45AM 10:45AM 11:15AM 11:15AM 11:45PM and Group Photo Thomas Kirchhausen, Harvard University (USA) Membrane dynamics in high resolution Dario Alessi, University of Dundee (UK)

5 11:45PM 12:00PM Short Talk 10 Rab phosphorylation and Parkinson s 12:00PM 1:00PM 1:00PM 6:00PM Session 6 7:00PM 9:45PM Free Time Group Activity Physico-Chemical Principles in Small GTPases Function Session Chair: Roger Williams, MRC-LMB (UK) Marino Zerial, MPI-CBG, Dresden (DE) Mechanics in membrane tethering and fusion Suzanne Pfeffer, Stanford University (USA) Rab tethering 8:00PM 8:15PM Short Talk 11 8:15PM 8:45PM 8:45PM 9:15PM 9:15PM 9:45PM Satyajit Mayor, NCBS Bangalore (IN) Cross-talk Arf1-Cdc42 in the regulation of tension-sensitive clathrinindependent endocytosis Wouter-Jan Rappel, UCSD (US) Computational and quantitative imaging methods to study biological processes Thursday, September 27, :30AM 9:00AM Session 7 9:00AM 12:15PM 10:00AM 10:30AM 10:30AM 11:00AM 11:00AM 11:30AM Spatial Regulation of Small GTPases Session Chair: Peter Novick, University of California (USA) Michiyuki Matsuda, Kyoto University (JP) Imaging Ras and Rho activation in human pathologies John Hancock, Institute of Molecular Medicine Houston (USA) Ras nanoclusters and the regulation of signaling by lipids Stephan Grill, University of Technology Dresden (DE) Rho oscillations in C. elegans embryo development Heidi McBride, McGill University (CA) GTPases in the cross-talk mitochondria-lysosomes

6 11:30AM 12:00PM Alpha Yap, IMB Brisbane (AU) Rho oscillations in cell polarity 12:00PM 12:15PM Short Talk 12 12:15PM 12:45PM 12:45PM 1:45PM 2:00PM 3:30PM Business Meeting Workshop: Mathematical Modeling in Cell Biology (Organizer: E. Sztul) Session 8 4:30PM 8:00PM Small GTPases in Cell Polarity, Migration and Tumorigenesis Session Chair: TBA: Johanna Ivaska University of Turku (FI) 4:30PM 5:00PM TBA 1 5:00PM 5:30PM Ian Macara, Vanderbilt University School of Medicine (USA) Function of Rho proteins in cell polarity and tumorigenesis 5:30PM 5:45PM Short Talk 13 5:45PM 6:00PM Short Talk 14 8:00PM 10:00PM Fernando Martin Belmonte, Centro de Biología Molecular Severo Ochoa (CBMSO), Madrid (ES) Small GTPases in epithelial morphogenesis and polarity Johanna Ivaska, University of Turku (FI) Regulation of integrin transport by Rho GTPases Posters and Wine Friday, September 28, :30AM 8:30AM Session 9 9:00AM 11:15AM 10:00PM 10:15PM 10:15AM 10:45AM Membrane Shaping and Membrane-Membrane Interactions Session Chair: Antonella De Matteis, Telethon Institute (IT) Harvey McMahon, MRC-LMB (UK) Regulation of fast endophilin-mediated endocytosis (FEME) J Todd Blankenship, University of Denver (US) Rab GTPases in Cell Polarization Marcos Gonzalez-Gaitan, University of Geneva (CH)

7 Rab GTPases in the partitioning of endosomes during asymmetric cell division: theory and experiments 10:45AM 11:35AM Session Chair: Marino Zerial Keynote Lecture Wolfgang Baumeister, Max Plank (DE) Cryo-electron tomography of macromolecular complexes 11:35AM 11:45AM 12:00PM Closing Comments Lunch to go and Departure END OF CONFERENCE