FINAL REPORT For Japan-Korea Joint Research Project AREA
|
|
- Aleesha Owen
- 5 years ago
- Views:
Transcription
1 (Form4-2) FINAL REPORT For Japan-Korea Joint Research Project AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical Science 7. Humanities & Social Sciences 1. Research Title: Physiological roles of extracellular proton on inflammasome functions using TDAG8 KO mouse 2. Term of Research: From July, 2010 To March, Total Budget a. Financial Support by JSPS: Total amount: 2,400 thousand yen 1 st Year 1,200 thousand yen 2 nd Year 1,200 thousand yen 3 rd Year 0 thousand yen b. Other Financial Support : Total amount: 0 thousand yen 4. Project Organization a. Japanese Principal Researcher Fumikazu Okajima Name Institution / Department Position Professor b. Korean Principal Researcher Name Dong-Soon Im Institution / Department Position College of Parmacy, Pusan University Associate Professor 1
2 c. List of Japanese-side Participants (Except for Principal Researcher) Name Institution/Department Position Hideaki Tomura Koichi Sato Chihiro Mogi Associate Professor Assistant Professor Assistant Professor Mayumi Komachi COE fellow Research Takashi Nakakura COE fellow Research d. List of Korean-side Participants (Except for Principal Researcher) Name Institution/Department Position Soo-Jin Pak College of Parmacy, Pusan University Pusan National University Graduate student 2
3 5. Number of Exchanges during the Final Fiscal Year* a. from Japan to Korea *Japanese fiscal year begins April 1. Name Home Institution Duration Host Institution Fumikazu Okajima Gunma University Feb , 2012 Kyung Hee University (Seoul), where I had a seminar and discussed our research projects with Dr Im DS of Pusan National University (a principal researcher of this project) and Dr. Jin Y of Kyung Hee University, who is an expert in the field related to our research project. Total: 1 persons Total: 5 man-days Numbers of Exchanges during the past fiscal years FY2009: Total 0 persons FY2010: Total 3 persons b. from Korea to Japan Name Home Institution Duration Host Institution Dong-Soon Im Pusan University National Feb. 1-4 Gunma Univerisity Soo-Jin Pak Pusan University National Feb. 1-4 Gunma University Total: 2 persons Total: 8 man-days Numbers of Exchanges during the past fiscal years FY2009: Total 0 persons FY2010: Total 1 persons 3
4 6. Objective of Research Korean principal researcher Dr. Im first reported that TDAG8 is a receptor for lysolipid psychosine in 2001 (Im, DS et al, J Cell Biol. 153, , 2001). On the other hand, we found in 2004 that TDAG8 senses extracellular proton or ph resulting in increase in intracellular camp accumulation through Gs-proteins (Wang, JQ et al, J. Biol. Chem. 279: ). Extracellular acidification has been shown to exert a variety of cellular responses; however, their molecular mechanisms remain poorly understood. Increase in extracellular proton or reduction of extracellular proton has been shown to occur in the sites under the states linked to deterioration of the blood supply like inflammation, ischaemia and tumor. We have recently observed the inhibitory effect of extracellular proton on cytokine release in macrophages using TDAG8 knock-out mice (Mogi, C et al, J. Immunol. 182, , 2009). We also found that extracellular acidification is associated with inhibition of IL-1b production in macrophages and microglia. Korean side investigator has researched on atherosclerosis at University of Connecticut and found involvement of inflammasome, which has been shown to be involved in the activation of caspase 1 and subsequent cleavage of proil-1b to mature Il-1b, in macrophages (Skoura, A., 2009). Thus, both principal researchers of Japan and Korea have contributed in the identification and characterization of the receptors. We therefore planned to elucidate the molecular mechanisms of proton/tdag8-regulated inflammasome functions using TDAG8 KO mouse. The elucidation of physiological roles and signal transduction pathways of extracellular proton and TDAG8 on lipopolysaccharide-induced IL-1b and IL-18 secretion in macrophages may facilitate understanding of the molecular mechanism of ph-dependent phenomena, which are frequently observed in several experimental systems. In addition, the proton-sensing GPCR may be therapeutic targets for immune diseases and inflammation. 7. Methodology As a corresponding author of the first publication in which TDAG8 was reported to sense extracellular proton to stimulate intracellular signaling pathways, I (Okajima) will characterize signal transduction mechanisms of proton and TDAG8 on inflammasome formation and IL-1b secretion in mouse using TDAG8 knock-out mouse. On the other hand, Korean principal researcher Dr. Im will try to clarify effects of extracellular proton or ph on the inflammasome formation and subsequent secretion of IL-1b in human THP-1 monocytes/macrophages. In order to perform these collaborative studies effectively, we mutually visit each laboratory at least once a year in addition to the frequent communication by . Year 2010 Dr. Im: He will investigate effect of extracellular proton on inflammasome formation by RT-PCR and Western blot, and imflammasome function by ELISA for IL-1b in human THP-1 monocytes/ macrophages. Okajima: We will test effect of extracellular proton on lipopolysaccharide (LPS)-induced inflammasome formation and function by Western blot and ELISA of IL-1b and IL-18 in mouse bone marrow-derived macrophages, thioglycollate-elicitated macrophages, and microglia in central nervous system. Futhermore, they can show involvement of TDAG8 by using TDAG8 KO mouse. Year 2011 Dr. Im: He will test TDAG8 involvement in extracellular proton-induecd inhibition on inflammasome function in human THP-1 monocytes/machrophages by using sirna strategy. We'll investigate effect of extracellular proton and TDAG8 on expression and interactions of 4
5 caspase 1, caspase 5, pycard (PYD nad CARD containing or ASC), and NALP3. Okajima: By investigating signal transduction pathways of TDAG8 as like camp formation and Rho activation, Japanese side will characterize signal transduction pathways involved in modulation of LPS-induced inflammasome formation and IL-1b secretion at the molecular level.
FINAL REPORT For Japan-Korea Joint Research Project
(Form4-2) FINAL REPRT For Japan-Korea Joint Research Project AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical
More informationFINAL REPORT For Japan-Korea Joint Research Project
(Form4-2) FINAL REPORT For Japan-Korea Joint Research Project AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical
More informationFINAL REPORT For Japan-Korea Joint Research Project
FINAL REPORT For Japan-Korea Joint Research Project AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical Science
More informationFINAL REPORT For Japan-Korea Joint Research Project AREA
(Form4-2) FINAL REPORT For Japan-Korea Joint Research Project AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical
More informationSUPPLEMENTARY INFORMATION
doi:10.1038/nature11419 Supplementary Figure 1 Schematic representation of innate immune signaling pathways induced by intracellular Salmonella in cultured macrophages. a, During the infection Salmonella
More informationBiology 580 Cellular Physiology Spring 2007 Course Syllabus
Class # 17416 MW 0800-0850 Biology 580 Cellular Physiology Spring 2007 Course Syllabus Course Text: Course Website: Molecular Biology of the Cell by Alberts et al.; 4th edition, Garland Science, 2002 (ISBN
More informationSupplementary Figure 1. AnnexinV FITC and Sytox orange staining in wild type, Nlrp3 /, ASC / and casp1/11 / TEC treated with TNF /CHX.
Supplementary Figure 1. AnnexinV FITC and Sytox orange staining in wild type, Nlrp3 /, ASC / and casp1/11 / TEC treated with TNF /CHX. Phase contrast and widefield fluorescence microscopy (20x magnification).
More informationScholarly Activity Improvement Fund (SAIF)-A 2012/2013 Final Report. Blocking signal pathway inter-connectors to reverse cell death
Scholarly Activity Improvement Fund (SAIF)-A 2012/2013 Final Report Blocking signal pathway inter-connectors to reverse cell death Chanaka Mendis Professor of Chemistry Department of Chemistry & Engineering
More informationFINAL REPORT For Japan-Korea Joint Seminar
FINAL REPORT For Japan-Korea Joint Seminar AREA 1. Mathematics & Physics 2. Chemistry & Material Science 3. Biology 4. Informatics & Mechatronics 5. Geo-Science & Space Science 6. Medical Science 7. Humanities
More informationDr. Marina Cvetkovska Department of Biology, University of Western Ontario North Campus Building, London, ON N6A 5B7
Dr. Marina Cvetkovska Department of Biology, University of Western Ontario North Campus Building, London, ON N6A 5B7 (519) 670-8841 mcvetko7@uwo.ca Research interests: I am interested in exploring biotic
More informationChem Lecture 10 Signal Transduction
Chem 452 - Lecture 10 Signal Transduction 111202 Here we look at the movement of a signal from the outside of a cell to its inside, where it elicits changes within the cell. These changes are usually mediated
More informationDelivery. Delivery Processes. Delivery Processes: Distribution. Ultimate Toxicant
Delivery Ultimate Toxicant The chemical species that reacts with the endogenous target. Toxicity depends on the concentration (dose) of the ultimate toxicant at the target site Delivery Processes Absorption
More informationCurriculum for the Master's Degree Programme in Molecular Cellular and Developmental Biology at the Faculty of Biology of the University of Innsbruck
The English version of this curriculum is not legally binding and is for informational purposes only. The legal basis is regulated in the curriculum published in the University of Innsbruck Bulletin on
More informationThe majority of cells in the nervous system arise during the embryonic and early post
Introduction Introduction The majority of cells in the nervous system arise during the embryonic and early post natal period. These cells are derived from population of neural stem cells first shown by
More informationRANK. Alternative names. Discovery. Structure. William J. Boyle* SUMMARY BACKGROUND
RANK William J. Boyle* Department of Cell Biology, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA * corresponding author tel: 805-447-4304, fax: 805-447-1982, e-mail: bboyle@amgen.com
More informationThe EGF Signaling Pathway! Introduction! Introduction! Chem Lecture 10 Signal Transduction & Sensory Systems Part 3. EGF promotes cell growth
Chem 452 - Lecture 10 Signal Transduction & Sensory Systems Part 3 Question of the Day: Who is the son of Sevenless? Introduction! Signal transduction involves the changing of a cell s metabolism or gene
More informationBig Idea 3: Living systems store, retrieve, transmit, and respond to information essential to life processes.
Big Idea 3: Living systems store, retrieve, transmit, and respond to information essential to life processes. Enduring understanding 3.A: Heritable information provides for continuity of life. Essential
More informationMap of AP-Aligned Bio-Rad Kits with Learning Objectives
Map of AP-Aligned Bio-Rad Kits with Learning Objectives Cover more than one AP Biology Big Idea with these AP-aligned Bio-Rad kits. Big Idea 1 Big Idea 2 Big Idea 3 Big Idea 4 ThINQ! pglo Transformation
More informationIntercellular communication
Intercellular communication Dewajani Purnomosari Department of Histology and Cell Biology Faculty of Medicine Universitas Gadjah Mada Outline General principle of intercellular communicabon Signal molecules
More informationMEDLINE Clinical Laboratory Sciences Journals
Source Type Publication Name ISSN Peer-Reviewed Academic Journal Acta Biochimica et Biophysica Sinica 1672-9145 Y Academic Journal Acta Physiologica 1748-1708 Y Academic Journal Aging Cell 1474-9718 Y
More informationSavannah State University New Programs and Curriculum Committee Summary Page Form I
Summary Page Form I 1. Submitting College: COST 2. Department(s) Generating The Proposal: Natural Sciences Choose an item. (if needed) 3. Proposal Title: Revised Chemistry Program Curriculum 4. Course
More informationEnduring understanding 1.A: Change in the genetic makeup of a population over time is evolution.
The AP Biology course is designed to enable you to develop advanced inquiry and reasoning skills, such as designing a plan for collecting data, analyzing data, applying mathematical routines, and connecting
More informationTitle of Project:Study of bacterial stratagem to circumvent host innate immune system and its application
Title of Project:Study of bacterial stratagem to circumvent host innate immune system and its application Chihiro Sasakawa ( The University of Tokyo, The Institute of Medical Science, Professor ) Research
More informationRegulation and signaling. Overview. Control of gene expression. Cells need to regulate the amounts of different proteins they express, depending on
Regulation and signaling Overview Cells need to regulate the amounts of different proteins they express, depending on cell development (skin vs liver cell) cell stage environmental conditions (food, temperature,
More informationREQUIREMENTS FOR THE BIOCHEMISTRY MAJOR
REQUIREMENTS FOR THE BIOCHEMISTRY MAJOR Grade Requirement: All courses required for the Biochemistry major (CH, MATH, PHYS, BI courses) must be graded and passed with a grade of C- or better. Core Chemistry
More informationProgrammed Cell Death
Programmed Cell Death Dewajani Purnomosari Department of Histology and Cell Biology Faculty of Medicine Universitas Gadjah Mada d.purnomosari@ugm.ac.id What is apoptosis? a normal component of the development
More informationA Multi-scale Extensive Petri Net Model of Bacterialmacrophage
A Multi-scale Extensive Petri Net Model of Bacterialmacrophage Interaction Rafael V. Carvalho Imaging & BioInformatics, Leiden Institute of Advanced Computer Science Introduction - Mycobacterial infection
More informationAdvanced Higher Biology. Unit 1- Cells and Proteins 2c) Membrane Proteins
Advanced Higher Biology Unit 1- Cells and Proteins 2c) Membrane Proteins Membrane Structure Phospholipid bilayer Transmembrane protein Integral protein Movement of Molecules Across Membranes Phospholipid
More informationCurriculum Links. AQA GCE Biology. AS level
Curriculum Links AQA GCE Biology Unit 2 BIOL2 The variety of living organisms 3.2.1 Living organisms vary and this variation is influenced by genetic and environmental factors Causes of variation 3.2.2
More informationREQUIREMENTS FOR THE BIOCHEMISTRY MAJOR
REQUIREMENTS FOR THE BIOCHEMISTRY MAJOR Grade Requirement: All courses required for the Biochemistry major (CH, MATH, PHYS, BI courses) must be graded and passed with a grade of C- or better. Core Chemistry
More informationA. Incorrect! The Cell Cycle contains 4 distinct phases: (1) G 1, (2) S Phase, (3) G 2 and (4) M Phase.
Molecular Cell Biology - Problem Drill 21: Cell Cycle and Cell Death Question No. 1 of 10 1. Which of the following statements about the cell cycle is correct? Question #1 (A) The Cell Cycle contains 3
More informationProgramme Specification (Undergraduate) For 2017/18 entry Date amended: 25/06/18
Programme Specification (Undergraduate) For 2017/18 entry Date amended: 25/06/18 1. Programme title(s) and UCAS code(s): BSc Biological Sciences C100 BSc Biological Sciences (Biochemistry) C700 BSc Biological
More informationSalmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation
http://dx.doi.org/10.4110/in.2012.12.6.284 pissn 1598-2629 eissn 2092-6685 BRIEF COMMUNICATION Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation Inhwa Hwang 1,2, Sangjun Park 1,2,
More informationReception The target cell s detection of a signal coming from outside the cell May Occur by: Direct connect Through signal molecules
Why Do Cells Communicate? Regulation Cells need to control cellular processes In multicellular organism, cells signaling pathways coordinate the activities within individual cells that support the function
More informationLABETTE COMMUNITY COLLEGE BRIEF SYLLABUS. ANATOMY AND PHYSIOLOGY, lecture and lab
LABETTE COMMUNITY COLLEGE BRIEF SYLLABUS SPECIAL NOTE: This brief syllabus is not intended to be a legal contract. A full syllabus will be distributed to students at the first class session. TEXT AND SUPPLEMENTARY
More informationAnnual Report for Research Work in the fiscal year 2005
JST Basic Research Programs C R E S T (Core Research for Evolutional Science and Technology) Annual Report for Research Work in the fiscal year 2005 Research Area : High Performance Computing for Multi-scale
More informationSCHOOL OF NATURAL SCIENCES AND TECHNOLOGY. CURRICULUM Since: August Degree: BACHELOR OF SCIENCE Credits: 153. Program: MEDICAL TECHNOLOGY
SCHOOL OF NATURAL SCIENCES AND TECHNOLOGY Degree: BACHELOR OF SCIENCE Credits: 5 CURRICULUM Since: August 08 Program: MEDICAL TECHNOLOGY Description: The Bachelor of Science with a Major in Medical Technology
More informationPREREQUISITE CHECKLIST
PREREQUISITE CHECKLIST UNIVERSITY OF CALIFORNIA, BERKELEY SCHOOL OF OPTOMETRY ADMISSIONS AND STUDENT AFFAIRS OFFICE Name: Date: Email: Status (complete, in progress, or planned) Prerequisite Course Requirements
More informationApproved Courses for General Science students with Major/Minors in Biological Sciences
Approved Courses for General Science students with Major/Minors in Biological Sciences List C: Physiology, cell and developmental biology BIOIN 301 Bioinformatics. * (fi 6) (first term, 3-0-0). Introduction
More informationWILLETTA TOOLE-SIMMS
ACADEMIC VITA FOR WILLETTA TOOLE-SIMMS ADDRESS Department of Biology Azusa Pacific University Azusa, CA 92557 (626) 969-3434 EDUCATIONAL BACKGROUND 1991-1992 Postdoctoral Training Chancellor s Postdoctoral
More informationSignal Transduction: Ethylene PSI AP Biology
Signal Transduction: Ethylene PSI AP Biology Name: Objective Students will analyze the role ethylene plays as a plant hormone in the signal transduction pathway of fruit ripening. Students will use their
More informationProblem Set 3 September 25, 2009
September 25, 2009 General Instructions: 1. You are expected to state all your assumptions and provide step-by-step solutions to the numerical problems. Unless indicated otherwise, the computational problems
More informationVCE BIOLOGY Relationship between the key knowledge and key skills of the Study Design and the Study Design
VCE BIOLOGY 2006 2014 Relationship between the key knowledge and key skills of the 2000 2005 Study Design and the 2006 2014 Study Design The following table provides a comparison of the key knowledge (and
More informationIntroduction Principles of Signaling and Organization p. 3 Signaling in Simple Neuronal Circuits p. 4 Organization of the Retina p.
Introduction Principles of Signaling and Organization p. 3 Signaling in Simple Neuronal Circuits p. 4 Organization of the Retina p. 5 Signaling in Nerve Cells p. 9 Cellular and Molecular Biology of Neurons
More informationThe Nobel Prize in Physiology or Medicine 1991
The Nobel Prize in Physiology or Medicine 1991 "for their discoveries concerning the function of single ion channels in cells" Erwin Neher Bert Sakmann 1/2 of the prize 1/2 of the prize Federal Republic
More informationDEPARTMENT OF SCIENCE
DEPARTMENT OF SCIENCE COURSE OUTLINE ZOOLOGY 2420 ANIMAL PHYSIOLOGY II: INTERCELLULAR COMMUNICATIONS INSTRUCTOR: Dr. Georgia Goth PHONE: 780-513-1041 OFFICE: J222 E-MAIL: ggoth@gprc.ab.ca OFFICE HOURS:
More information1 of 13 8/11/2014 10:32 AM Units: Teacher: APBiology, CORE Course: APBiology Year: 2012-13 Chemistry of Life Chapters 1-4 Big Idea 1, 2 & 4 Change in the genetic population over time is feedback mechanisms
More informationUndergraduate Curriculum in Biology
Fall Courses *114: Principles of Biology *116: Introduction to Anatomy and Physiology I 302: Human Learning and the Brain (o, DS) 336: Aquatic Biology (p/e) 339: Aquatic Biology Lab (L) 351: Principles
More informationJob Announcement for an Assistant Professor at the Institute of Space and Astronautical Science, the Japan Aerospace Exploration Agency
Job Announcement for an Assistant Professor at the Institute of Space and Astronautical Science, the Japan Aerospace Exploration Agency The Japan Aerospace Space Exploration Agency (JAXA) is seeking to
More informationDesigning Caspase-1 kinase inhibitors to control acute inflammation of Orthodontic Appliances.
Designing Caspase-1 kinase inhibitors to control acute inflammation of Orthodontic Appliances. Ashleigh Augello, 1 Earl Benjamin, 1 Ellis Benjamin* 1 Department of Chemistry, The Richard Stockton College
More informationIII. ENGINEERING. Contents
III. ENGINEERING Contents Students with Advanced Placement credit:... 1 Engineering 8-semester plans... 2 Biomedical Concentration... 2 Civil Concentration... Computer Concentration... 4 Electrical Concentration...
More informationBIOH111. o Cell Biology Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system
BIOH111 o Cell Biology Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system Endeavour College of Natural Health endeavour.edu.au 1 Textbook
More informationProteomics. Areas of Interest
Introduction to BioMEMS & Medical Microdevices Proteomics and Protein Microarrays Companion lecture to the textbook: Fundamentals of BioMEMS and Medical Microdevices, by Prof., http://saliterman.umn.edu/
More informationBioimage Informatics. Lecture 23, Spring Emerging Applications: Molecular Imaging
Bioimage Informatics Lecture 23, Spring 2012 Emerging Applications: Molecular Imaging Lecture 23 April 25, 2012 1 Outline Overview of molecular imaging Molecular imaging modalities Molecular imaging applications
More informationCritical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1
Immunity 24, 317 327, March 2006 ª2006 Elsevier Inc. DOI 10.1016/j.immuni.2006.02.004 Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1 Fayyaz
More informatione-publication (Yes/No) Molecular Microbiology Wiley, United States of America
FORMAT FOR SUBJECTWISE IDENTIFYING JOURNALS BY THE UNIVERSITIES AND APPROVAL OF THE UGC {Under Clause 6.05 (1) of the University Grants Commission (Minimum Qualifications for appointment of Teacher and
More informationEssential knowledge 1.A.2: Natural selection
Appendix C AP Biology Concepts at a Glance Big Idea 1: The process of evolution drives the diversity and unity of life. Enduring understanding 1.A: Change in the genetic makeup of a population over time
More informationMedical Physiology. Medical Physiology. Introduction and Control Theory Learning objectives # 1. The subject. What to expect. Feed back
Medical Physiology Introduction and Control Theory Learning objectives # 1. Prof. Gyula Sáry 1 Medical Physiology The subject What to expect Feed back www.markmyprofessor.com Domoki.Ferenc@med.u-szeged.hu
More informationFSC-W FSC-H CD4 CD62-L
Supplementary Fig. 1 a SSC-A FSC-A FSC-W FSC-H SSC-W SSC-H CD4 CD62-L b SSC-A FSC-A FSC-W FSC-A FSC-A 7-AAD FSC-A CD4 IL-9 CD4 c SSC-A FSC-A FSC-W FSC-H SSC-W SSC-H 7-AAD KI67 Annexin-V 7-AAD d I L -5
More informationA A A A B B1
LEARNING OBJECTIVES FOR EACH BIG IDEA WITH ASSOCIATED SCIENCE PRACTICES AND ESSENTIAL KNOWLEDGE Learning Objectives will be the target for AP Biology exam questions Learning Objectives Sci Prac Es Knowl
More informationAPPENDIX II. Laboratory Techniques in AEM. Microbial Ecology & Metabolism Principles of Toxicology. Microbial Physiology and Genetics II
APPENDIX II Applied and Environmental Microbiology (Non-Thesis) A. Discipline Specific Requirement Biol 6484 Laboratory Techniques in AEM B. Additional Course Requirements (8 hours) Biol 6438 Biol 6458
More informationAP Biology Essential Knowledge Cards BIG IDEA 1
AP Biology Essential Knowledge Cards BIG IDEA 1 Essential knowledge 1.A.1: Natural selection is a major mechanism of evolution. Essential knowledge 1.A.4: Biological evolution is supported by scientific
More informationThe Role of G-Protein Coupled Estrogen Receptor (GPER) in Early Neurite Development. Kyle Pemberton
The Role of G-Protein Coupled Estrogen Receptor (GPER) in Early Neurite Development Kyle Pemberton Acknowledgement Dr. Xu Lab Members Brittany Mersman Nicki Patel Pallavi Mhaskar Jason Cocjin Committee
More informationBig Idea 1: The process of evolution drives the diversity and unity of life.
Big Idea 1: The process of evolution drives the diversity and unity of life. understanding 1.A: Change in the genetic makeup of a population over time is evolution. 1.A.1: Natural selection is a major
More informationIII. ENGINEERING. Contents
III. ENGINEERING Contents Students with Advanced Placement credit:... 1 Engineering 8-semester plans... 2 Biomedical Concentration... 2 Civil Concentration... Computer Concentration... 4 Electrical Concentration...
More informationAP Curriculum Framework with Learning Objectives
Big Ideas Big Idea 1: The process of evolution drives the diversity and unity of life. AP Curriculum Framework with Learning Objectives Understanding 1.A: Change in the genetic makeup of a population over
More informationIntroduction to Cellular Communication *
OpenStax-CNX module: m53235 1 Introduction to Cellular Communication * Steven Telleen This work is produced by OpenStax-CNX and licensed under the Creative Commons Attribution License 4.0 1 Why Cells Communicate
More informationAdvanced Anatomy and Physiology
Lakeshore Technical College 10806179 Advanced Anatomy and Physiology Course Outcome Summary Course Information Alternate Title Description Total Credits 4 Total Hours 90 Adv Anatomy & Physiology Advanced
More informationDiscovery of compounds that keep plants fresh ~ Controlling plant pore openings for drought tolerance and delay in leaf withering ~
Discovery of compounds that keep plants fresh ~ Controlling plant pore openings for drought tolerance and delay in leaf withering ~ April 9, 2018 A team of scientists at Nagoya University has discovered
More informationThe Institute of Cancer Research PHD STUDENTSHIP PROJECT PROPOSAL
The Institute of Cancer Research PHD STUDENTSHIP PROJECT PROPOSAL PROJECT DETAILS Project Title: Design and synthesis of libraries of bifunctional degraders for the discovery of new cancer targets SUPERVISORY
More informationHow does a cell communicate? AP Biology Curriculum Framework
Enduring Understanding 3.D Cells communicate by generating, transmitting and receiving chemical signals. 1 Endocrine & Cell Communication Part I: Introduction to Communication You may wish to print a copy
More informationBEFORE TAKING THIS MODULE YOU MUST ( TAKE BIO-4013Y OR TAKE BIO-
2018/9 - BIO-4001A BIODIVERSITY Autumn Semester, Level 4 module (Maximum 150 Students) Organiser: Dr Harriet Jones Timetable Slot:DD This module explores life on Earth. You will be introduced to the major
More informationSig2GRN: A Software Tool Linking Signaling Pathway with Gene Regulatory Network for Dynamic Simulation
Sig2GRN: A Software Tool Linking Signaling Pathway with Gene Regulatory Network for Dynamic Simulation Authors: Fan Zhang, Runsheng Liu and Jie Zheng Presented by: Fan Wu School of Computer Science and
More informationCRISPR-SeroSeq: A Developing Technique for Salmonella Subtyping
Department of Biological Sciences Seminar Blog Seminar Date: 3/23/18 Speaker: Dr. Nikki Shariat, Gettysburg College Title: Probing Salmonella population diversity using CRISPRs CRISPR-SeroSeq: A Developing
More informationCell-Cell Communication in Development
Biology 4361 - Developmental Biology Cell-Cell Communication in Development October 2, 2007 Cell-Cell Communication - Topics Induction and competence Paracrine factors inducer molecules Signal transduction
More informationPAMP-triggered immunity (PTI)
PAMP-triggered immunity (PTI) PAMP-triggered immunity (PTI) Recognition of danger signals - Distinguish self or damaged self versus non-self fundamental to any immune system - PAMP or MAMP pathogen/microbe-associated
More informationIntroduction to me, High-Energy Physics and research at Belle
Introduction to me, High-Energy Physics and research at Belle Jan Schümann Belle Collaboration Tsukuba, Japan Where I come from: Europe Germany Henstedt-Ulzburg... small village of 25.000 citizens My village...
More informationintroduction Endothelin-1 Inhibits Inward Rectifier K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells Through Protein Kinase C
Current Topic 6 ก มภาพ นธ 2549 เวลา 9.00-12.00 น. น าเสนอโดย น.ส.สายวร ณ ศร ร ง 4836203 อาจารย ท ปร กษา อ.นพ.ล อชา บ ญทว ก ล Endothelin-1 Inhibits Inward Rectifier K+ Channels in Rabbit Coronary Arterial
More informationLigand screening system using fusion proteins of G protein coupled receptors with G protein α subunits
2 Ligand screening system using fusion proteins of G protein coupled receptors with G protein α subunits G protein coupled receptors A key player of signaling transduction. Cell membranes are packed with
More informationGraduate Education in Institute of Chemistry, Chinese Academy of Sciences
At 2014 IUPAC World Polymer Congress (MACRO 2014) July 6-11, Chiang Mai, Thailand Graduate Education in Institute of Chemistry, Chinese Academy of Sciences Jiasong He Institute of Chemistry, Chinese Academy
More informationAP Biology Gene Regulation and Development Review
AP Biology Gene Regulation and Development Review 1. What does the regulatory gene code for? 2. Is the repressor by default active/inactive? 3. What changes the repressor activity? 4. What does repressor
More informationCell Cell Communication in Development
Biology 4361 Developmental Biology Cell Cell Communication in Development June 25, 2008 Cell Cell Communication Concepts Cells in developing organisms develop in the context of their environment, including
More information5- Semaphorin-Plexin-Neuropilin
5- Semaphorin-Plexin-Neuropilin 1 SEMAPHORINS-PLEXINS-NEUROPILINS ligands receptors co-receptors semaphorins and their receptors are known signals for: -axon guidance -cell migration -morphogenesis -immune
More informationApoptosis & Autophagy
SPETSAI SUMMER SCHOOL 2010 Host Microbe Interactions Cellular Response to Infection: Apoptosis & Autophagy Christoph Dehio There are many ways to die Apoptosis: Historical perspective Process of programmed
More informationCOMPUTER SIMULATION OF DIFFERENTIAL KINETICS OF MAPK ACTIVATION UPON EGF RECEPTOR OVEREXPRESSION
COMPUTER SIMULATION OF DIFFERENTIAL KINETICS OF MAPK ACTIVATION UPON EGF RECEPTOR OVEREXPRESSION I. Aksan 1, M. Sen 2, M. K. Araz 3, and M. L. Kurnaz 3 1 School of Biological Sciences, University of Manchester,
More informationConclusions. The experimental studies presented in this thesis provide the first molecular insights
C h a p t e r 5 Conclusions 5.1 Summary The experimental studies presented in this thesis provide the first molecular insights into the cellular processes of assembly, and aggregation of neural crest and
More informationPrerequisite: CHEM 1311 General Chemistry I (lecture) and CHEM 1111 General Chemistry I Laboratory or CHEM 1411.
BIOL 2321 Microbiology for Science Majors COURSE SYLLABUS COURSE NUMBER AND TITLE: BIOL 2321 Microbiology for Science Majors (lecture) COURSE (CATALOG) DESCRIPTION: This course is an introduction to the
More informationDEFINING THE PLAYERS IN HIGHER-ORDER NETWORKS: PREDICTIVE MODELING FOR REVERSE ENGINEERING FUNCTIONAL INFLUENCE NETWORKS
DEFINING THE PLAYERS IN HIGHER-ORDER NETWORKS: PREDICTIVE MODELING FOR REVERSE ENGINEERING FUNCTIONAL INFLUENCE NETWORKS JASON E. MCDERMOTT 1, MICHELLE ARCHULETA 1, SUSAN L. STEVENS 2, MARY P. STENZEL-POORE
More informationStaffing formula and enrollment limits X Other REMOVAL of GWAR attribute
CALIFORNIA STATE UNIVERSITY CHANNEL ISLANDS COURSE MODIFICATION PROPOSAL Courses must be submitted by October 15, 2013, and finalized by the end of the fall semester to make the next catalog (2014-15)
More informationCHEMISTRY (CHE) CHE 104 General Descriptive Chemistry II 3
Chemistry (CHE) 1 CHEMISTRY (CHE) CHE 101 Introductory Chemistry 3 Survey of fundamentals of measurement, molecular structure, reactivity, and organic chemistry; applications to textiles, environmental,
More informationCaspase 3-mediated cleavage of the vacuolar proton-pumping ATPase subunit ATP6V1B2
Caspase 3-mediated cleavage of the vacuolar proton-pumping ATPase subunit ATP6V1B2 Usnish Majumdar Mentored by Prof. James Mandell, M.D., Ph.D. UVa Medical Center, Department of Pathology Supported by
More informationAssessment of toxicological properties and establishment of risk profiles - genotoxic properties of selected spice compounds
Assessment of toxicological properties and establishment of risk profiles - genotoxic properties of selected spice compounds Frankfurt/Main, September 25 th 212 V.J. Koller 1, V. Auwärter 2, G. Zlabinger
More informationPrereq: Concurrent 3 CH
0201107 0201101 General Biology (1) General Biology (1) is an introductory course which covers the basics of cell biology in a traditional order, from the structure and function of molecules to the structure
More informationAC Program/Major or Minor/Concentration Revision Form (07/2004)
1.0 Degree Title Specify the two degrees for concurrent degree programs B.A. & Sc. 1.1 Major (Legacy= Subject) (30-char. max.) Biomedical Sciences 1.2 Concentration (Legacy = Concentration/Option) If applicable
More informationSubject Matter and Geography Education
Subject Matter and Geography Education Kwang Joon Cho Seoul Teachers College As Subject Education appears, the idea of the subject becomes clear arid the goals of Subject Education come to focus on character
More informationHong Kong Meteorological Society 香港氣象學會.
Hong Kong Meteorological Society 香港氣象學會 www.meteorology.org.hk Founded in 1989, to promote meteorology via local and international activities Fellowship Open to any meteorologist or any scholar with research
More informationBiochemistry-BS Program Study Abroad Pathway
Biochemistry-BS Program Study Abroad Pathway (last revised September 2016) Table 1a: Undergraduate Program Schedule These undergraduate program schedules are subject to change. Please verify information
More informationMolecular Cell Biology 5068 In Class Exam 2 November 8, 2016
Molecular Cell Biology 5068 In Class Exam 2 November 8, 2016 Exam Number: Please print your name: Instructions: Please write only on these pages, in the spaces allotted and not on the back. Write your
More informationMOLECULAR BIOLOGY BIOL 021 SEMESTER 2 (2015) COURSE OUTLINE
COURSE OUTLINE 1 COURSE GENERAL INFORMATION 1 Course Title & Course Code Molecular Biology: 2 Credit (Contact hour) 3 (2+1+0) 3 Title(s) of program(s) within which the subject is taught. Preparatory Program
More informationScience Course Descriptions
BIOLOGY I (L) 3024 (BIO I) Biology I is a course based on the following core topics: cellular chemistry, structure and reproduction; matter cycles and energy transfer; interdependence of organisms; molecular
More information