HISTORICAL CONTROL DATA OF SPERM ANALYSES FROM 2-GENERATION AND FERTILITY STUDIES IN HsdRccHan TM : WIST, Wistar Hannover Rats
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1 HISTORICAL CONTROL DATA OF SPERM ANALYSES FROM 2-GENERATION AND FERTILITY STUDIES IN HsdRccHan TM : WIST, Wistar Hannover Rats Compiled from 2-Generation and Fertility Studies performed at RCC Ltd. Itingen/Switzerland
2 Historical control data of sperm analyses from 2-generation and fertility studies in HasRccHan TM : WIST, Wistar Hannover Rats Contents: Table 1: Study identification 3 Table 2: Sperm analysis - motility 4 Table 3: Sperm analysis - morphology 5 Table 4: Sperm analysis - sperm head count 8 Table 5: Statistics sperm analysis - motility 9 Table 6: Statistics sperm analysis - morphology 10 Table 7: Statistics sperm analysis - sperm head count 11 2
3 Table 1: Study identification Study ID Number of study Date of performance GEN/Seg / Gen / Gen Seg I 4 A Seg I 3
4 Table 2: Sperm analysis - motilty P-Generation Unit Not motile mean % st. dev n (litters) 24 9* Stat. motile mean % st. dev n (litters) 24 9* Prog. motile mean % st. dev n (litters) 24 9* F1 - Generation Unit Not motile mean % st. dev Stat. motile mean % st. dev Prog. motile mean % st. dev * = Animal No. 10: small left testis & epididymidis; excluded from summary tables 4
5 Table 3: Sperm analysis - morphology P- Generation Unit A mean 93.3* 94.4** 93.6** 93.1** % st. dev B mean 3.2* 1.9** 2.81** 2.8** % st. dev C mean 0.8* 0.4** 0.8** 0.6** % st. dev D mean 2.3* 3.0** 2.4** 3.0** % st. dev E mean 0.0* 0.0** 0.0** 0.0** % st. dev F mean 0.4* 0.3** 0.4** 0.5** % st. dev
6 Table 3: Sperm analysis - morphology. Cont'd F1-Generation Unit A mean 92.6* 94.4* - - % st. dev B mean 2.9* 1.9* - - % st. dev C mean 0.9* 0.5* - - % st. dev D mean 3.2* 2.4* - - % st. dev E mean 0.1* 0.0* - - % st. dev F mean 0.3* 0.7* - - % st. dev
7 Table 3: Sperm analysis - morphology. Cont'd * A = Normal, complete sperm B = Normal head only (tail C = Complete sperm with D = Complete sperm with E = Complete sperm with reversed F = Abnormal head only (tail ** A = Sperm with normal hook and tail B = Normal hook without tail C = Misshapen sperm hook with tail D = Sperm with abnormal curved hook with tail E = Sperm with reversed hook with tail F = Abnormal hook without tail *** = Animal No. 10: small left testis & epididymidis; excluded from summary tables 7
8 Table 4: Sperm analysis - sperm head count P-Generation Unit Cauda Epidid mean mio/g Org. st. dev n (litters) 24 9* Testis mean mio/g Org. st. dev n (litters) 24 9* F1-Generation Unit Cauda Epidid mean mio/g Org. st. dev Testis mean mio/g Org. st. dev * = Animal No. 10: small left testis & epididymidis; excluded from summary tables 8
9 Table 5: Statistics sperm analysis - motility P-Generation Unit Total n Mean STDEV MIN MAX Not motile mean n (litters) Stat. motile mean n (litters) Prog. motile mean n (litters) F1 -Generation Unit Total n Mean STDEV MIN MAX Not motile mean Stat. motile mean Prog. motile mean * = Animal No. 10: small left testis & epididymidis; excluded from summary tables 9
10 Table 6: Statistics sperm analysis - morphology P-Generation Unit Total n Mean STDEV MIN MAX A mean B mean C mean D mean E mean F mean Table 6: Statistics sperm analysis - morphology. Cont'd F1-Generation Unit Total n Mean STDEV MIN MAX A mean B mean C mean D mean E mean F mean
11 Table 7: Statistics sperm analysis - sperm head count P-Generation Unit Total n Mean STDEV MIN MAX Cauda Epidid mean mio/g Org. st. dev Testis mean mio/g Org. st. dev F1-Generation Unit Total n Mean STDEV MIN MAX Cauda Epidid mean mio/g Org. st. dev Testis mean mio/g Org. st. dev
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