Charles Yanofsky. Morris Herzstein Professor of Biology, Emeritus

Transcription

1 Morris Herzstein Professor of Biology, Emeritus Bio ACADEMIC APPOINTMENTS Emeritus Faculty, Acad Council, Biology Professor Emeritus, Biology Publications PUBLICATIONS Tryptophan Inhibits Proteus vulgaris TnaC Leader Peptide Elongation, Activating tna Operon Expression JOURNAL OF BACTERIOLOGY Cruz-Vera, L. R., Yang, R., 2009; 191 (22): S rrna Nucleotides in the Peptidyl Transferase Center Are Essential for Tryptophanase Operon Induction JOURNAL OF BACTERIOLOGY Yang, R., Cruz-Vera, L. R., 2009; 191 (11): Conserved residues Asp16 and Pro24 of TnaC-tRNA(Pro) participate in tryptophan induction of tna operon expression JOURNAL OF BACTERIOLOGY Cruz-Vera, L. R., 2008; 190 (14): Physiological effects of anti-trap protein activity and trna(trp) charging on trp operon expression in Bacillus subtilis JOURNAL OF BACTERIOLOGY Cruz-Vera, L. R., Gong, M., 2008; 190 (6): A genetic selection for Neurospora crassa mutants altered in their light regulation of transcription GENETICS Navarro-Sampedro, L.,, Corrochano, L. M. 2008; 178 (1): RNA-based regulation of genes of tryptophan synthesis and degradation, in bacteria RNA-A PUBLICATION OF THE RNA SOCIETY 2007; 13 (8): Ribosome recycling factor and release factor 3 action promotes TnaC-peptidyl-tRNA dropoff and relieves ribosome stalling during tryptophan induction of tna operon expression in Escherichia coli JOURNAL OF BACTERIOLOGY Gong, M., Cruz-Vera, L. R., 2007; 189 (8): Ribosomal features essential for tna operon induction: Tryptophan binding at the peptidyl transferase center JOURNAL OF BACTERIOLOGY Cruz-Vera, L. R., New, A., Squires, C., 2007; 189 (8): Establishing the triplet nature of the genetic code CELL Page 1 of 9

2 2007; 128 (5): Charles Yanofsky Changes produced by bound tryptophan in the ribosome peptidyl transferase center in to TnaC, a nascent leader peptide PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Cruz-Vera, L. R., Gong, M., 2006; 103 (10): Overexpression of tnac of Escherichia coli inhibits growth by depleting trna(2)(pro) availability JOURNAL OF BACTERIOLOGY Gong, M., Gong, F., 2006; 188 (5): Features of ribosome-peptidyl-trna interactions essential for tryptophan induction of tna operon expression MOLECULAR CELL Cruz-Vera, L. R., Rajagopal, S., Squires, C., 2005; 19 (3): Effects of tryptophan starvation on levels of the trp RNA-binding attenuation protein (TRAP) and anti-trap regulatory protein and their influence on trp operon expression in Bacillus subtilis JOURNAL OF BACTERIOLOGY Yang, W. J., 2005; 187 (6): The favorable features of tryptophan synthase for proving Beadle and Tatum's one gene-one enzyme hypothesis GENETICS 2005; 169 (2): Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis ANNUAL REVIEW OF GENETICS Gollnick, P., Babitzke, P., Antson, A., 2005; 39: The different roles of tryptophan transfer RNA in regulating trp operon expression in E-coli versus B-subtilis TRENDS IN GENETICS 2004; 20 (8): Features of a leader peptide coding region that regulate translation initiation for the anti-trap protein of B-subtilis MOLECULAR CELL Chen, G. N., 2004; 13 (5): A transcriptional pause synchronizes translation with transcription in the tryptophanase operon leader region JOURNAL OF BACTERIOLOGY Gong, F., 2003; 185 (21): Tandem transcription and translation regulatory sensing of uncharged tryptophan trna SCIENCE Chen, G. N., 2003; 301 (5630): Using studies on tryptophan metabolism to answer basic biological questions JOURNAL OF BIOLOGICAL CHEMISTRY 2003; 278 (13): Rho's role in transcription attenuation in the tna operon of E-coli RNA POLYMERASES AND ASSOCIATED FACTORS, PT D Gong, F., 2003; 371: Zinc is required for assembly and function of the anti-trp RNA-binding attenuation protein, AT JOURNAL OF BIOLOGICAL CHEMISTRY Valbuzzi, A., 2002; 277 (50): Instruction of translating ribosome by nascent peptide SCIENCE Gong, F., 2002; 297 (5588): Page 2 of 9

3 Analysis of tryptophanase operon expression in vitro - Accumulation of TnaC-peptidyl-tRNA in a release factor 2-depleted S-30 extract prevents Rho factor action, simulating induction JOURNAL OF BIOLOGICAL CHEMISTRY Gong, F., 2002; 277 (19): The anti-trp RNA-binding attenuation protein (anti-trap), AT, recognizes the tryptophan-activated RNA binding domain of the TRAP regulatory protein JOURNAL OF BIOLOGICAL CHEMISTRY Valbuzzi, A., Gollnick, P., Babitzke, P., 2002; 277 (12): Inhibition of the B-subtilis regulatory protein TRAP by the TRAP-inhibitory protein, AT SCIENCE Valbuzzi, A., 2001; 293 (5537): The mechanism of tryptophan induction of tryptophanase operon expression: Tryptophan inhibits release factor-mediated cleavage of TnaC-peptidyltRNA(Pro) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Gong, F., Ito, K., Nakamura, Y., 2001; 98 (16): Reproducing tna operon regulation in vitro in an S-30 system - Tryptophan induction inhibits cleavage of TnaC peptidyl-rna? JOURNAL OF BIOLOGICAL CHEMISTRY Gong, F., 2001; 276 (3): Advancing our knowledge in biochemistry, genetics, and microbiology through studies on tryptophan metabolism ANNUAL REVIEW OF BIOCHEMISTRY 2001; 70: 1-37 DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Khodursky, A. B., Peter, B. J., Cozzarelli, N. R., Botstein, D., Brown, P. O., 2000; 97 (22): Rho-dependent transcription termination in the tna operon of Escherichia coli: Roles of the boxa sequence and the rut site JOURNAL OF BACTERIOLOGY Konan, K. V., 2000; 182 (14): A Bacillus subtilis gene of previously unknown function, yhag, is translationally regulated by tryptophan-activated TRAP and appears to be involved in tryptophan transport JOURNAL OF BACTERIOLOGY Sarsero, J. P., Merino, E., 2000; 182 (8): A Bacillus subtilis operon containing genes of unknown function senses trna(trp) charging and regulates expression of the genes of tryptophan biosynthesis PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Sarsero, J. P., Merino, E., 2000; 97 (6): Transcription attenuation: Once viewed as a novel regulatory strategy JOURNAL OF BACTERIOLOGY 2000; 182 (1): 1-8 Role of ribosome release in regulation of tna operon expression in Escherichia coli JOURNAL OF BACTERIOLOGY Konan, K. V., 1999; 181 (5): Regulation of the Escherichia coli tna operon: Nascent leader peptide control at the tnac stop codon JOURNAL OF BACTERIOLOGY Konan, K. V., 1997; 179 (5): Page 3 of 9

4 Characterization of rco-1 of Neurospora crassa, a pleiotropic gene affecting growth and development that encodes a homolog of Tup1 of Saccharomyces cerevisiae MOLECULAR AND CELLULAR BIOLOGY Yamashiro, C. T., Ebbole, D. J., Lee, B. U., BROWN, R. E., Bourland, C., Madi, L., 1996; 16 (11): A temperature-sensitive trps mutation interferes with trp RNA-binding attenuation protein (TRAP) regulation of trp gene expression in Bacillus subtilis JOURNAL OF BACTERIOLOGY Lee, A. I., Sarsero, J. P., 1996; 178 (22): Loss or overproduction of polypeptide release factor 3 influences expression of the tryptophanase operon of Escherichia coli JOURNAL OF BACTERIOLOGY, Horn, V., Nakamura, Y. 1996; 178 (13): On the role of helix 0 of the tryptophan synthetase alpha chain of Escherichia coli JOURNAL OF BIOLOGICAL CHEMISTRY Yee, M. C., Horn, V., 1996; 271 (25): Flexibility of DNA binding domain of trp repressor required for recognition of different operator sequences PROTEIN SCIENCE Gryk, M. R., Jardetzky, O., Klig, L. S., 1996; 5 (6): Some novel transcription attenuation mechanisms used by bacteria OJI Seminar on Posttranscriptional Control of Gene Expression: The Regulatory Role of RNA, Konan, K. V., Sarsero, J. P. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER.1996: EVIDENCE SUGGESTING CIS ACTION BY THE TNAC LEADER PEPTIDE IN REGULATING TRANSCRIPTION ATTENUATION IN THE TRYPTOPHANASE OPERON OF ESCHERICHIA-COLI JOURNAL OF BACTERIOLOGY Gish, K., 1995; 177 (24): TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)-TRP LEADER RNA INTERACTIONS MEDIATE TRANSLATIONAL AS WELL AS TRANSCRIPTIONAL REGULATION OF THE BACILLUS-SUBTILIS TRP OPERON JOURNAL OF BACTERIOLOGY Merino, E., Babitzke, P., 1995; 177 (22): TRAP, THE TRP RNA-BINDING ATTENUATION PROTEIN OF BACILLUS-SUBTILIS, IS A TOROID-SHAPED MOLECULE THAT BINDS TRANSCRIPTS CONTAINING GAG OR UAG REPEATS SEPARATED BY 2 NUCLEOTIDES PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Babitzke, P., Bear, D. G., 1995; 92 (17): BICYCLOMYCIN SENSITIVITY AND RESISTANCE AFFECT RHO-FACTOR-MEDIATED TRANSCRIPTION TERMINATION IN THE TNA OPERON OF ESCHERICHIA-COLI JOURNAL OF BACTERIOLOGY, Horn, V. 1995; 177 (15): STRUCTURAL FEATURES OF L-TRYPTOPHAN REQUIRED FOR ACTIVATION OF TRAP, THE TRP RNA-BINDING ATTENUATION PROTEIN OF BACILLUS-SUBTILIS JOURNAL OF BIOLOGICAL CHEMISTRY Babitzke, P., 1995; 270 (21): LIGHT AND DEVELOPMENTAL REGULATION OF THE GENE CON-10 OF NEUROSPORA-CRASSA DEVELOPMENTAL BIOLOGY Corrochano, L. M., Lauter, F. R., Ebbole, D. J., 1995; 167 (1): ROLE OF REGULATORY FEATURES OF THE TRP OPERON OF ESCHERICHIA-COLI IN MEDIATING A RESPONSE TO A NUTRITIONAL SHIFT JOURNAL OF BACTERIOLOGY, Horn, V. Page 4 of 9

5 1994; 176 (20): Charles Yanofsky TRAP, THE TRP RNA-BINDING ATTENUATION PROTEIN OF BACILLUS-SUBTILIS, IS A MULTISUBUNIT COMPLEX THAT APPEARS TO RECOGNIZE G/UAG REPEATS IN THE TRPEDCFBA AND TRPG TRANSCRIPTS JOURNAL OF BIOLOGICAL CHEMISTRY Babitzke, P., Stults, J. T., Shire, S. J., 1994; 269 (24): A COPY OF INSERTION ELEMENT IS5 IS PRESENT WITHIN TNAB IN THE KOHARA LIBRARY OF ESCHERICHIA-COLI W3110 JOURNAL OF BACTERIOLOGY Kamath, A. V., Gish, K., 1994; 176 (5): SEQUENCE AND CHARACTERIZATION OF MUTT FROM PROTEUS-VULGARIS GENE Kamath, A. V., 1993; 134 (1): STRUCTURAL CHARACTERIZATION AND EXPRESSION ANALYSIS OF THE NEUROSPORA CONIDIATION GENE CON-6 DEVELOPMENTAL BIOLOGY White, B. T., 1993; 160 (1): DAY-NIGHT AND CIRCADIAN-RHYTHM CONTROL OF CON GENE-EXPRESSION IN NEUROSPORA PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Lauter, F. R., 1993; 90 (17): ANALYSIS OF HETERODIMER FORMATION BY THE ESCHERICHIA-COLI TRP REPRESSOR JOURNAL OF BIOLOGICAL CHEMISTRY Hurlburt, B. K., 1993; 268 (20): INHIBITION OF EXPRESSION OF THE TRYPTOPHANASE OPERON IN ESCHERICHIA-COLI BY EXTRACHROMOSOMAL COPIES OF THE TNA LEADER REGION JOURNAL OF BACTERIOLOGY Gish, K., 1993; 175 (11): PARTIAL REVERTANTS OF TRYPTOPHAN SYNTHETASE-ALPHA CHAIN ACTIVE-SITE MUTANT ASP60-]ASN JOURNAL OF BIOLOGICAL CHEMISTRY, Yee, M. C., Horn, V. 1993; 268 (11): RECONSTITUTION OF BACILLUS-SUBTILIS TRP ATTENUATION INVITRO WITH TRAP, THE TRP RNA-BINDING ATTENUATION PROTEIN PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Babitzke, P., 1993; 90 (1): A DOMINANT SELECTABLE MARKER THAT IS MEIOTICALLY STABLE IN NEUROSPORA-CRASSA - THE AMDS GENE OF ASPERGILLUS- NIDULANS MOLECULAR & GENERAL GENETICS Yamashiro, C. T., Yarden, O., 1992; 236 (1): DEVELOPMENTAL AND LIGHT REGULATION OF EAS, THE STRUCTURAL GENE FOR THE RODLET PROTEIN OF NEUROSPORA GENES & DEVELOPMENT Lauter, F. R., Russo, V. E., 1992; 6 (12A): CHARACTERIZATION OF THE TRYPTOPHANASE OPERON OF PROTEUS-VULGARIS - CLONING, NUCLEOTIDE-SEQUENCE, AMINO- ACID HOMOLOGY, AND INVITRO SYNTHESIS OF THE LEADER PEPTIDE AND REGULATORY ANALYSIS JOURNAL OF BIOLOGICAL CHEMISTRY Kamath, A. V., 1992; 267 (28): Page 5 of 9

6 TRP REPRESSOR/TRP OPERATOR INTERACTION - EQUILIBRIUM AND KINETIC-ANALYSIS OF COMPLEX-FORMATION AND STABILITY JOURNAL OF BIOLOGICAL CHEMISTRY Hurlburt, B. K., 1992; 267 (24): TIMING OF SYNTHESIS AND CELLULAR-LOCALIZATION OF 2 CONIDIATION-SPECIFIC PROTEINS OF NEUROSPORA- CRASSA DEVELOPMENTAL BIOLOGY Springer, M. L., Hager, K. M., GARRETTENGELE, C., 1992; 152 (2): EXPRESSION OF CON GENES ALONG THE 3 SPORULATION PATHWAYS OF NEUROSPORA-CRASSA GENES & DEVELOPMENT Springer, M. L., 1992; 6 (6): COT-1, A GENE REQUIRED FOR HYPHAL ELONGATION IN NEUROSPORA-CRASSA, ENCODES A PROTEIN-KINASE EMBO JOURNAL Yarden, O., Plamann, M., Ebbole, D. J., 1992; 11 (6): THE MTRAB OPERON OF BACILLUS-SUBTILIS ENCODES GTP CYCLOHYDROLASE-I (MTRA), AN ENZYME INVOLVED IN FOLIC-ACID BIOSYNTHESIS, AND MTRB, A REGULATOR OF TRYPTOPHAN BIOSYNTHESIS JOURNAL OF BACTERIOLOGY Babitzke, P., Gollnick, P., 1992; 174 (7): THE NH2-TERMINAL ARMS OF TRP REPRESSOR PARTICIPATE IN REPRESSOR/OPERATOR ASSOCIATION NUCLEIC ACIDS RESEARCH Hurlburt, B. K., 1992; 20 (2): CHITIN SYNTHASE-1 PLAYS A MAJOR ROLE IN CELL-WALL BIOGENESIS IN NEUROSPORA-CRASSA GENES & DEVELOPMENT Yarden, O., 1991; 5 (12B): DEVELOPMENTAL EXPRESSION OF GENES INVOLVED IN CONIDIATION AND AMINO-ACID BIOSYNTHESIS IN NEUROSPORA- CRASSA DEVELOPMENTAL BIOLOGY Sachs, M. S., 1991; 148 (1): PHYSIOLOGICAL-STUDIES OF TRYPTOPHAN TRANSPORT AND TRYPTOPHANASE OPERON INDUCTION IN ESCHERICHIA- COLI JOURNAL OF BACTERIOLOGY, Horn, V., Gollnick, P. 1991; 173 (19): THE EFFECTS OF LEADER PEPTIDE SEQUENCE AND LENGTH ON ATTENUATION CONTROL OF THE TRP OPERON OF ESCHERICHIA- COLI NUCLEIC ACIDS RESEARCH Roesser, J. R., 1991; 19 (4): CPC-1, THE GENERAL REGULATORY GENE FOR GENES OF AMINO-ACID BIOSYNTHESIS IN NEUROSPORA-CRASSA, IS DIFFERENTIALLY EXPRESSED DURING THE ASEXUAL LIFE-CYCLE MOLECULAR AND CELLULAR BIOLOGY Ebbole, D. J., Paluh, J. L., Plamann, M., Sachs, M. S., 1991; 11 (2): CHARACTERIZATION OF NEUROSPORA CPC1, A BZIP DNA-BINDING PROTEIN THAT DOES NOT REQUIRE ALIGNED HEPTAD LEUCINES FOR DIMERIZATION MOLECULAR AND CELLULAR BIOLOGY Paluh, J. L., 1991; 11 (2): GENES EXPRESSED DURING CONIDIATION IN NEUROSPORA-CRASSA - MOLECULAR CHARACTERIZATION OF CON-13 GENE Hager, K. M., 1990; 96 (2): Page 6 of 9

7 THE MTR LOCUS IS A 2-GENE OPERON REQUIRED FOR TRANSCRIPTION ATTENUATION IN THE TRP OPERON OF BACILLUS- SUBTILIS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Gollnick, P., Ishino, S., Kuroda, M. I., Henner, D. J., 1990; 87 (22): CLONING, SEQUENCE, AND PHOTOREGULATION OF AL-1, A CAROTENOID BIOSYNTHETIC GENE OF NEUROSPORA- CRASSA MOLECULAR AND CELLULAR BIOLOGY Schmidhauser, T. J., Lauter, F. R., Russo, V. E., 1990; 10 (10): THE NEUROSPORA-CRASSA ARG-2 LOCUS - STRUCTURE AND EXPRESSION OF THE GENE ENCODING THE SMALL SUBUNIT OF ARGININE-SPECIFIC CARBAMOYL PHOSPHATE SYNTHETASE JOURNAL OF BIOLOGICAL CHEMISTRY Orbach, M. J., Sachs, M. S., 1990; 265 (19): NEUROSPORA-CRASSA A MATING-TYPE REGION PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Staben, C., 1990; 87 (13): TRANSFER RNATRP TRANSLATION OF LEADER PEPTIDE CODON-12 AND OTHER FACTORS THAT REGULATE EXPRESSION OF THE TRYPTOPHANASE OPERON JOURNAL OF BACTERIOLOGY Gollnick, P., 1990; 172 (6): ENHANCED OPERATOR BINDING BY TRP SUPERREPRESSORS OF ESCHERICHIA-COLI JOURNAL OF BIOLOGICAL CHEMISTRY Hurlburt, B. K., 1990; 265 (14): ESCHERICHIA-COLI MUTANT TRPA34 HAS AN ASP-]ASN CHANGE AT ACTIVE-SITE RESIDUE-60 OF THE TRYPTOPHAN-SYNTHETASE ALPHA-CHAIN JOURNAL OF BIOLOGICAL CHEMISTRY SHIRVANEE, L., Horn, V., 1990; 265 (12): THE RNA ANTITERMINATOR CAUSES TRANSCRIPTION PAUSING IN THE LEADER REGION OF THE TRYPTOPHAN OPERON JOURNAL OF BIOLOGICAL CHEMISTRY Roesser, J. R., 1990; 265 (11): DETERMINATION OF THE INACTIVATING ALTERATIONS IN 2 MUTANT ALLELES OF THE NEUROSPORA-CRASSA CROSS-PATHWAY CONTROL GENE CPC-1 GENETICS Paluh, J. L., Plamann, M., Kruger, D., Barthelmess, I. B.,, Perkins, D. D. 1990; 124 (3): EVOLUTION OF THE TRYPTOPHAN-SYNTHETASE OF FUNGI - ANALYSIS OF EXPERIMENTALLY FUSED ESCHERICHIA-COLI TRYPTOPHAN SYNTHETASE-ALPHA AND SYNTHETASE-BETA CHAINS JOURNAL OF BIOLOGICAL CHEMISTRY Burns, D. M., Horn, V., Paluh, J., 1990; 265 (4): REGULATION OF BASAL LEVEL EXPRESSION OF THE TRYPTOPHAN OPERON OF ESCHERICHIA-COLI JOURNAL OF BIOLOGICAL CHEMISTRY Roesser, J. R., Nakamura, Y., 1989; 264 (21): A MORPHOLOGICAL AND GENETIC-ANALYSIS OF CONIDIOPHORE DEVELOPMENT IN NEUROSPORA-CRASSA GENES & DEVELOPMENT Springer, M. L., 1989; 3 (4): NUCLEOTIDE-SEQUENCE OF THE NEUROSPORA-CRASSA TRP-3 GENE ENCODING TRYPTOPHAN-SYNTHETASE AND COMPARISON OF THE TRP-3 POLYPEPTIDE WITH ITS HOMOLOGS IN SACCHAROMYCES-CEREVISIAE AND ESCHERICHIA-COLI JOURNAL OF BIOLOGICAL CHEMISTRY Page 7 of 9

8 Burns, D. M., 1989; 264 (7): Charles Yanofsky GENES EXPRESSED DURING CONIDIATION IN NEUROSPORA-CRASSA - CHARACTERIZATION OF CON-8 NUCLEIC ACIDS RESEARCH Roberts, A. N., 1989; 17 (1): TRYPTOPHAN-SYNTHETASE OF ESCHERICHIA-COLI - A MULTIFUNCTIONAL, MULTICOMPONENT ENZYME - A COMMENTARY ON A 2ND REACTION CATALYZED BY THE TRYPTOPHAN-SYNTHETASE OF ESCHERICHIA-COLI BIOCHIMICA ET BIOPHYSICA ACTA 1989; 1000: DEVELOPMENT OF A TRPE PROMOTER-STRENGTH MEASURING SYSTEM AND ITS USE IN COMPARISON OF THE TRPEDCBA, TRPR AND AROH PROMOTERS JOURNAL OF MOLECULAR BIOLOGY Cho, K. O., 1988; 204 (1): SEQUENCE CHANGES PRECEDING A SHINE-DALGARNO REGION INFLUENCE TRPE MESSENGER-RNA TRANSLATION AND DECAY JOURNAL OF MOLECULAR BIOLOGY Cho, K. O., 1988; 204 (1): ND-SITE REVERTANTS OF ESCHERICHIA-COLI TRP REPRESSOR MUTANTS GENETICS Klig, L. S., Oxender, D. L., 1988; 120 (3): RIBOSOME RELEASE MODULATES BASAL LEVEL EXPRESSION OF THE TRP OPERON OF ESCHERICHIA-COLI JOURNAL OF BIOLOGICAL CHEMISTRY Roesser, J. R., 1988; 263 (28): TRP REPRESSOR INTERACTIONS WITH THE TRP AROH AND TRPR OPERATORS - COMPARISON OF REPRESSOR BINDING INVITRO AND REPRESSION INVIVO JOURNAL OF MOLECULAR BIOLOGY Klig, L. S., Carey, J., 1988; 202 (4): CIS-ACTING SITES IN THE TRANSCRIPT OF THE BACILLUS-SUBTILIS TRP OPERON REGULATE EXPRESSION OF THE OPERON JOURNAL OF BACTERIOLOGY Kuroda, M. I., Henner, D., 1988; 170 (7): THE CROSS-PATHWAY CONTROL GENE OF NEUROSPORA-CRASSA, CPC-1, ENCODES A PROTEIN SIMILAR TO GCN4 OF YEAST AND THE DNA-BINDING DOMAIN OF THE ONCOGENE V-JUN-ENCODED PROTEIN PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Paluh, J. L., Orbach, M. J., LEGERTON, T. L., 1988; 85 (11): MOLECULAR ANALYSIS OF A NEUROSPORA-CRASSA GENE EXPRESSED DURING CONIDIATION MOLECULAR AND CELLULAR BIOLOGY Roberts, A. N., Berlin, V., Hager, K. M., 1988; 8 (6): CLONING OF METHYLATED TRANSFORMING DNA FROM NEUROSPORA-CRASSA IN ESCHERICHIA-COLI MOLECULAR AND CELLULAR BIOLOGY Orbach, M. J., Schneider, W. P., 1988; 8 (5): AN ELECTROPHORETIC KARYOTYPE OF NEUROSPORA-CRASSA MOLECULAR AND CELLULAR BIOLOGY Orbach, M. J., Vollrath, D., Davis, R. W., 1988; 8 (4): TRANSCRIPTION ATTENUATION JOURNAL OF BIOLOGICAL CHEMISTRY Page 8 of 9

9 1988; 263 (2): Charles Yanofsky INCREASED BINDING OF OPERATOR DNA BY TRP SUPERREPRESSOR EK49 JOURNAL OF BIOLOGICAL CHEMISTRY Klig, L. S., 1988; 263 (1): ISOLATION AND STRUCTURAL-ANALYSIS OF THE ESCHERICHIA-COLI-TRP LEADER PAUSED TRANSCRIPTION COMPLEX JOURNAL OF MOLECULAR BIOLOGY Landick, R., 1987; 196 (2): HYBRID IMMUNOGLOBULIN ISOTYPES OF IDENTICAL SPECIFICITY PRODUCED BY GENETIC-RECOMBINATION IN ESCHERICHIA- COLI AND EXPRESSION IN LYMPHOID-CELLS PROTEINS-STRUCTURE FUNCTION AND GENETICS Schneider, W. P., Oi, V. T., 1987; 2 (2): EFFICIENT CLONING OF GENES OF NEUROSPORA-CRASSA PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vollmer, S. J., 1986; 83 (13): COMPARISON OF REGULATORY AND STRUCTURAL REGIONS OF GENES OF TRYPTOPHAN-METABOLISM MOLECULAR BIOLOGY AND EVOLUTION 1984; 1 (2): COMPLETE AMINO ACID SEQUENCE OF TRYPTOPHAN SYNTHETASE A PROTEIN (ALPHA SUBUNIT) AND ITS COLINEAR RELATIONSHIP WITH GENETIC MAP OF A GENE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, DRAPEAU, G. R., Guest, J. R., CARLTON, B. C. 1967; 57 (2): 296-? THE FORMATION OF A NEW ENZYMATICALLY ACTIVE PROTEIN AS A RESULT OF SUPPRESSION PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA CRAWFORD, I. P., 1959; 45 (8): THE EFFECTS OF DELETIONS, POINT MUTATIONS, REVERSIONS AND SUPPRESSOR MUTATIONS ON THE 2 COMPONENTS OF THE TRYPTOPHAN SYNTHETASE OF ESCHERICHIA-COLI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, CRAWFORD, I. P. 1959; 45 (7): ON THE SEPARATION OF THE TRYPTOPHAN SYNTHETASE OF ESCHERICHIA-COLI INTO 2 PROTEIN COMPONENTS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA CRAWFORD, I. P., 1958; 44 (12): Page 9 of 9