Progress in Molecular and Subcellular Biology 39. Echinodermata. Bearbeitet von Valeria Matranga
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1 Progress in Molecular and Subcellular Biology 39 Echinodermata Bearbeitet von Valeria Matranga 1. Auflage Buch. xxiii, 275 S. Hardcover ISBN Format (B x L): 15,5 x 23,5 cm Gewicht: 619 g Weitere Fachgebiete > Technik > Verfahrenstechnik, Chemieingenieurwesen, Lebensmitteltechnik > Kosmetische Technologie Zu Leseprobe schnell und portofrei erhältlich bei Die Online-Fachbuchhandlung beck-shop.de ist spezialisiert auf Fachbücher, insbesondere Recht, Steuern und Wirtschaft. Im Sortiment finden Sie alle Medien (Bücher, Zeitschriften, CDs, ebooks, etc.) aller Verlage. Ergänzt wird das Programm durch Services wie Neuerscheinungsdienst oder Zusammenstellungen von Büchern zu Sonderpreisen. Der Shop führt mehr als 8 Millionen Produkte.
2 Contents Are Echinoderms of Interest to Biotechnology? C. Petzelt References Cell Adhesion and Communication: A Lesson from Echinoderm Embryos for the Exploitation of New Therapeutic Tools 7 F. Zito, C. Costa, S. Sciarrino, C. Cavalcante, V. Poma, V. Matranga 1 Introduction Why Study Echinoderms? Echinoderms for Biomedical Research: A Simple Model to Study Biological Events Occurring in Higher Organisms Screening for and Testing of Toxic Substances From Echinoderm Molecules to Mammalian Diseases: How Fundamental Research Points to Clinical Trials Highly Conserved Proteins Associated with Important Biological Functions Use of Echinoderm Embryos to Study the Basic Mechanisms of Communication Among Cells Sea Urchin Embryo Transparency: A Laboratory Study on Development and Morphogenesis ECM Patterning in Echinoids During Embryo Development 19 4 Apical Cell Surface The Apical Lamina The Hyaline Layer Pl-Nectin: An Example of Signal(s) from Outside to Inside the Embryo Other Apical ECM Components Basal Cell Surface The Blastocoel Matrix Receptors to ECM Molecules Lateral Cell Surface
3 XVIII Contents 8.1 Cell Cell Adhesion and Communication: The Discovery of Toposome Other Cell Cell Adhesion Molecules Cell Junctions Signalling Pathways Growth Factors Concluding Remarks References Cell Signalling During Sea Urchin Development: A Model for Assessing Toxicity of Environmental Contaminants C. Angelini, M.G. Aluigi, M. Sgro, S. Trombino, H. Thielecke, C. Falugi 1 Basic Research Cell-to-Cell Signalling During Sea Urchin Development Fertilisation First Phase: Sperm Activation Second Phase: Egg Activation First Cell Cycle Cleavages Ongoing Research Applied Research Neurotoxic Contaminants Health Risks Mode of Function of Organophosphates and Carbamates Persistence in the Environment and Crops Biosensors Effects of Neurotoxic Compounds on P. lividus Ion Dynamics References Echinoderm Reactive Oxygen Species (ROS) Production Measured by Peroxidase, Luminol-Enhanced Chemiluminescence (PLCL) as an Immunotoxicological Tool G. Coteur, B. Danis, P. Dubois 1 Introduction Measurement of Reactive Oxygen Species (ROS) Production 73 3 Modulation of ROS Production by Environmental Factors Impact of Metal Contaminations Impact of PCB Contaminations Impact of Complex Contaminations Discussion References
4 Contents XIX Monitoring Chemical and Physical Stress Using Sea Urchin Immune Cells =8 V. Matranga, A. Pinsino, M. Celi, A. Natoli, R. Bonaventura, H.C. Schröder, W.E.G. Müller 1 Introduction Echinoderm Coelomocytes as Immune Effector Cells: Morphological Features and Recognized Functions The Origin of Coelomocytes: Terminally Differentiated or Circulating Stem Cells? Molecules Expressed by Echinoderm Coelomocytes Innate Immune Molecules: The Complement System Agglutinins, Lectins and Adhesion Molecules Cytoskeleton Proteins NK Antigens and Cytokines Stress Response Proteins Cell Cultures of Coelomocytes: New Tools to Detect Marine Pollution Laboratory Experiments Field Studies The Northern Adriatic Sea: First Example of Monitoring Metal Pollution The Southern Adriatic Sea: A Case Study for the Assessment of TNT Exposure The North Sea: A Norwegian Fiord as a Natural Gradient of Metal Contamination Concluding Remarks References DNA Damage and Developmental Defects After Exposure to UV and Heavy Metals in Sea Urchin Cells and Embryos Compared to Other Invertebrates H.C. Schröder, G. Di Bella, N. Janipour, R. Bonaventura, R. Russo, W.E.G. Müller,V. Matranga 1 Introduction Atmospheric Ozone Penetration of Solar UV Radiation in Marine Waters Effects of Solar UV Radiation on Aquatic Organisms DNA Damage DNA Repair Solar UV Radiation and Evolution Heavy Metals Marine Invertebrates as Bioindicators
5 XX Contents 2.1 Sea Urchins Sea Urchin Coelomocytes Assay for DNA Integrity Radiation Source Full Solar Spectrum Lamp UV-B Lamp DNA Damage in Coelomocytes UV Radiation Cadmium Combined Effects Expression of HSP Experimental Approach Effect of UV-B Radiation on P. lividus Embryo Development Effect of Cadmium on P. lividus Embryo Development Porifera Sponge Primmorphs UV Radiation Cadmium Combined Effects DNA Repair (6 4) Photolyase Corals Concluding Remarks References Echinoderms: Their Culture and Bioactive Compounds M.S. Kelly 1 Why Cultivate? Sea Urchin Aquaculture Life History and State of the Art Sea Urchin Larviculture Metamorphosis and the Post-Larval Stage Sea Urchin Grow-Out Systems Juvenile and Adult Somatic Versus Gonadal Growth Artificial Diets Carotenoids in Sea Urchin Diets Sea Urchin Harvest Protocol, Spoilage and Shelf-Life Disease in Cultured Sea Urchins Sea Cucumber Aquaculture Life History and State of the Art Sea Cucumber Larviculture Metamorphosis and the Post-Larval Stage Sea Cucumber Growth to Maturity
6 Contents XXI 3.5 Disease in Cultured Holothurians Bioactive Compounds from Echinoderms Triterpene Glycosides Glycosaminoglycans: Chondroitin Sulphate Neuritogenic Gangliosides Antimicrobial Activity Other Types of Bioactive Compounds: Branched-Chain Fatty Acids, Lectins, Opsonins, Analgesics and Anti-ulcer Compounds Regeneration of Nerve Tissue and Arm Regrowth in Crinoids Sustainable Development The Research Requirement Environmental Considerations Economic Considerations References Regenerative Response and Endocrine Disrupters in Crinoid Echinoderms: An Old Experimental Model, a New Ecotoxicological Test M.D. Candia Carnevali 1 Regeneration and its Biological Implications Regeneration in Echinoderms The Regenerative Potential of Crinoids Endocrine Disrupters and Echinoderms Crinoid Regeneration and Endocrine Disrupters Experimental Approach Exposure Experiments PCB Exposure NP Exposure TPT-Cl Exposure Biological Analysis Chemical Analysis: Summary of Analytical Procedures and Results PCBs NP TPT-Cl Exposure Effects of EDs and Biological Implications on Regeneration Mortality Growth Malformations
7 XXII Contents 4.4 Histological Pattern Conclusions References Echinoderm Adhesive Secretions: From Experimental Characterization to Biotechnological Applications P. Flammang, R. Santos, D. Haesaerts 1 Introduction Tube Feet Larval Adhesive Organs Cuvierian Tubules Applications of Marine Bioadhesives Design of Water-Resistant Adhesives Development of New Antifouling Strategies The Potential of Echinoderm Adhesives References Mutable Collagenous Tissue: Overview and Perspectives I.C. Wilkie 1 Introduction Collagenous Tissue Mechanical Adaptability of Collagenous Tissue Mutable Collagenous Tissue: Physiology and Organisation Overview Mechanical Adaptability of MCT Passive Mechanical Properties Active Contractility Organisation of MCT Cells Extracellular Matrix Molecular Mechanism of MCT Mutability Are Collagen Fibrils Involved? Are Calcium Ions Involved? Tensilin Tensilin Protease Hypothesis Active Force Generation Mutable Collagenous Tissue: Biotechnological Perspective Current Commercial Uses of MCT Biotechnological Potential of MCT Pharmacological Agents or Strategies New Composite Materials Concluding Remarks References
8 Contents XXIII Bioresources from Echinoderms Y. Yokota 1 Introduction Oriental Medicine and Historical Background Saponins Glycolipids Pigments Venoms Hemagglutinin Prospects Appendix: Antique Illustrations of Echinoderms in Japan. 257 References Subject Index
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