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1 Resume DR. MANMOHAN CHHIBBER Assistant Professor, School of Chemistry and Biochemistry y, Thapar University, Patiala , (Office- Phone) India Contact : mchhibber@thapar.edu (Fax) Academic Qualifications Degree Ph.D. (Chemistry) M.Sc Honours School (Chemistry) B.Sc Honours School (Chemistry) Teaching & Professional Experience Year College/University Panjab University, Chandigarh Panjab University, Chandigarh Panjab University, Chandigarh Position Held Assistant Professor Supervisor Quality Control Name of the Period Organization From To Thapar Patiala University, June 2007 Onwards Montari Industries March 1995 August 2000 Limited, Chandigarh Responsibilities Teaching and Research Quality Control RESEARCH INTRESTS Synthetic Organic Chemistry: My research interests revolve around synthesiss and application of diphenyl ethers, amines and its derivatives. Primary aim of synthesizing these molecules is to find their use as potential antibacterial agents. Triclosan, diphenyl ether, is known to obstruct fatty acid biosynthesis in most bacteria by inhibiting one of the enzymes (enoyl-acp-reductase) chemistry to mold these molecules to create voids so that they can be used responsible for the same. In addition to antibacterial potential, we use synthetic organic (i) (ii) For the detection of cations or anions via electro analytical techniques. For the creation of metal-organic-framework (MOFs). WE WILL BE PLEASED TO FIND MORE COLLOBORATORS FOR PUTING OUR MOLECULES TO THE BEST USE.
2 RESEARCH EXPERIENCE Experience after PhD (Post-Doctoral) Organization Period from To Duration Molecular Biophysics Unit Indian Institute of Science (IISc), Jan 2003 June Years 6 months Bangalore, India Sponsored Research Projects S. No. A. Completed Title of Project Co-Investigator Sponsoring Agency Duration Amount 1. Syntheis, characterization and evaluation of antibacterial activity of new diphenyl ether based organic molecules. 2. Technology development of novel biopolymers for Potable water treatment B. Ongoing 3. Design and development ofdiphenylether based supramolecuculesfor electroanalytical probes. 4. Synthesis and characterization ofdiphenyl ether/analogues for theirantibacterial activity None Dr. Moushumi Ghosh, DBTES Thapar University, Dr. Susheel Mittal, School of Chemistry, Thapar University Thapar University DST BRNS (DAE) None UGC Ph.D. Students S. No. Name Broad Area of Work Co-Supervisor 1. Ramandeep Kaur Synthesis of diphenyl ethers / amines for None antibacterial activity. 2. Harpreet Kaur Synthesis of diphenyl ethers for electro Prof. S. Mittal analytical studies with metal ions. 3. Ramkrusha A Salunke Synthesis of fluoroquinolones for Dr. B. R. Bansal antibacterial activity. 4. Amita Mehta Improvement in the activity of known diphenyl ethers. None
3 M.Sc. Students Guided for Thesis: Fifteen LIST OF PUBLICATIONS International 1. Gurpreet Kaur Khaira, Rashmi Kumariya, Manmohan Chibber and Moushumi Ghosh; Development of a quaternized chitosan with enhanced antibacterial efficacy, Journal of Water and Health, (2013), 11, ( ISI Journal Impact Factor for 2012: 1.22) 2. Satnam S. Aulakh, ManmohanChhibber, RasikaMantri and RanjanaPrakash; Whole cell catalyzed esterification of fatty acids to biodiesel using Aspergillussp., Biocatalysis and Biotransformation, (2011), 29, BhaskarChetnani, Parimal Kumar, K. V. Abhinav, ManmohanChhibber, A. Surolia, and M. Vijayan; Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosispantothenate kinase: insights into enzyme action, Acta Crystallographica Section D,(2011), D67, Ira Surolia, ManmohanChhibber, Debi Prasad Sarkar and SharmisthaSinha;Fibrillogenesis in ADan peptides is inhibited by biphenyl ethers, Biochemical and Biophysical Research Communications,(2008), 370, Sarika Gupta, ManmohanChhibber, SharmisthaSinha and AvadheshaSurolia; Design of Mechanism-Based Inhibitors of Transthyretin Amyloidosis: Studies with Biphenyl Ethers and New Structural Templates, Journal of Medicinal Chemistry,( 2007), 50, These authors have made equal contributions. 6. Parimal Kumar, ManmohanChhibber, AvadheshaSurolia; How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis, Biochemical and Biophysical Research Communications, (2007), 361, ManmohanChhibber, Gyanendra Kumar, PrasannaParasuraman, T. N. C. Ramya, NamitaSurolia and AvadheshaSurolia; Novel diphenyl ethers: Design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli,bioorganic & Medicinal Chemistry, (2006),14, ManmohanChhibber; Potassium Fluoride on Alumina (KF/Al 2 O 3 ), Synlett, (2004), (This is a mini review article) 9. JasvinderSingha, Munisha Sharma, ManmohanChhibber, JasamritKaur and Goverdhan L. Kad;Chemoselective Oxidation of Benzylic Alcohols with Solid Supported CrO 3 /TBHP Under Microwave Irradiation, Synthetic Communications, (2000), 30, National 10. Satnam Singh, SnehaAggrawal, ManmohanChhibber and RanjanaPrakash; Lipase Catalyzed
4 Transesterification of Cottonseed Oil, Journal of Pure & Applied Microbiology,(2010), 4, PATENTS AWARDED 1. Shilpi Sharma, NamitaSurolia, PrasannaParasuraman, AvadheshaSurolia, ManmohanChhibber, Sanjay Kumar, Shailendra K Sharma and Gyanendra, Kumar; 2-Thixothiazolidin-4-one compounds and composition as antimicrobial and antimalarial agents targeting enoylacoreductase of type II fatty acid synthesis pathway and other cell growth pathway, Australian Patent No: dated AvadheshaSurolia, NamitaSurolia, Gyanendra, Kumar, ManmohanChhibber, PrasannaParasuraman, Sanjay Kumar, Shailendra K Sharma and Shilpi Sharma; 2- Thixothiazolidin-4-one compounds and composition as antimicrobial and antimalarial agents targeting enoyl-acoreductase of type II fatty acid synthesis pathway and other cell growth pathway, Singapore Patent No: dated CONFERENCES A. Referred International Conferences 1. Gyanendra Kumar, ManmohanChhibber, PrasannaParasuraman, Ramya T. N. Chakravarthy, NamitaSurolia, and AvadheshaSurolia; Novel diphenyl ethers: Design, docking studies and inhibition of enoyl ACP reductase from Plasmodium falciparum and Escherichia coli and their structure activity relationship, 233rd ACS National Meeting, Chicago, IL, USA,March 25-29, Organized by American Chemical Society. B. Un-Referred National Conferences 1. G.L.Kad, J.S. Brar, IrvinderKaur and ManmohanChhibber, Synthesis of Dihalide Compounds via the Oxidation of Terminal Olefins using QCC/I 2 under Microwave Irradiation, 13 th Annual National Symposium at Department of Chemistry, Panjab University, Chandigarh. March 11, Organized by Department of Chemistry, Panjab University, Chandigarh. 2. ManmohanChhibber, JasamritKaur and I. R. Trehan; Synthesis of Dihydrocoumarins in Dry Media using Microwaves, 3 rd National Symposium in Chemistry (NSC-3) atdepartment of Chemistry, Panjab University, Chandigarh. February 2-4, Organized by Chemical Research Society of India, Bangalore. 3. ManmohanChhibber, JasamritKaur and I. R. Trehan; Synthesis of Dihydrocoumarins in Dry Media using Microwaves, Indo-German Workshop on Soft Matter Research by NMR and Holography in Association with 14 th National SymposiumatDepartment of Chemistry, Panjab University, Chandigarh. March 17-18, Organized by Department of Chemistry, Panjab University, Chandigarh. 4. ManmohanChhibber, JasamritKaur and I. R. Trehan; A Convenient Approach to Synthesize Two Naturally OccuringSesquiterpenes, 4 th National Symposium in Chemistry (NSC-4) at National Chemical Laboratory, Pune and University of Pune, Pune. February 1-3, 2002.
5 Organized by Chemical Research Society of India, Bangalore. 5. ManmohanChhibber, JasamritKaur and I. R. Trehan; A Convenient Approach to Synthesize Two Naturally Occurring Sesquiterpenes, 15 th Annual National Symposium at Department of Chemistry, Panjab University, Chandigarh. March 23, Organized by Department of Chemistry, Panjab University, Chandigarh. 6. ManmohanChhibber, PrasannaParasuraman, Ramya T. N. Chakravarthy, Gyanendra Kumar, NamitaSurolia, and AvadheshaSurolia; Diphenyl ethers for the inhibition of enoyl-acp-reductase of P. Falciparum, National Conference on Innovations in Drug Discovery and Research at Department of Pharmaceutical Sciences, Punjabi University, Patiala.March 3-5,2009. Organized by Department of Pharmaceutical Sciences, Punjabi University, Patiala. 7. RamandeepKaur and ManmohanChhibber; Diphenyl ether molecules as antibacterial agents, National Conference on Recent Advances in Chemical & Environmental Sciences held M.M.Modi College, Patiala from March 3, Organized by PG Department of Chemistry, M.M.Modi College, Patiala 8. Amita Mehta and ManmohanChhibber; Intelectins for the recognition of bacterial cell surface sugars, National Conference on Recent Advances in Chemical & Environmental Sciences held M.M.Modi College, Patiala from March 3, Organized by PG Department of Chemistry, M.M.Modi College, Patiala DETAILS OF HONORS A. Invited Talks S. No. Title Date Venue Organizers 1. Pheromones : Importance, Utility and Synthesis 2. Fatty Acid Synthase II: Possible New Drug Target for Antimalarials and Antibacterial. 3. UV-Visible Spectroscopy (Faculty Development Programme) 4. Nature : An Ultimate Source of Inspiration for Science and Society 5. Hopping Across Disciplines : The Need of Hour November 16, 2006 February 17, 2007 July 22, 2011 February 15, 2012 March 24, 2012 JawaharLal Nehru Planetarium, Bangalore Bangalore Association for Science and Education (BASE) IIIT, Hyderabad IIIT, Hyderabad Rayat-Bahra Engineering College, Mohali, Punjab MCM DAV College for Women, Chandigarh Aryan College, Rajpura, Patiala Rayat- Bahra Engineering College and PTU, Jallandhar Science Association of MCM DAV College for Women. Aryan College, Rajpura, Patiala
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