Postulated Mechanisms of Action for Biological Effects from Electromagnetic Fields

Transcription

1 Postulated Mechanisms of Action for Biological Effects from Electromagnetic Fields Vladimir N. Binhi General Physics Institute, Russian Academy of Sciences

2 A Brief History of Magnetobiology before 1960 a few isolated works, including EM safety standards microwaves ELF modulation kt problem since 1980 ELF MFs added now Hz RF (cell phones frequencies) number of publications publications per year exponential growth to year

3 Types of Biological Effects from EM Fields Non-thermal effects PROPERTIES: 1. Interdisciplinary character 2. Reproducibility 3. Theory/experiment comparison 4. Social significance Microwaves: heating 1 mw/cm 2 Thermal effects ELF: induction ELF: heating

4 Some Standards of Electromagnetic Safety Electric Field Strength / V/m 10k 1k Hz ICNIRP CENELEC USA Russia k 10k 100k 1M 10M 100M 1G 10G 100G 1T Power Density / mw/cm ICNIRP CENELEC USA Russia Russia M 100M 1G 10G 100G 1T Frequency / Hz Frequency / Hz

5 Example of Observed Frequency Spectrum MBE, rel. units MBE, Alipov and Belyaev, 1996 theory for Ca theory for Na P, arb. units f, Hz

6 Example of Amplitude Dependence ИОФ РАН 80 Blackman et al., MBE / % H ac /H dc

7 Classification of the MBE models Phenomenological models Macroscopic models Microscopic models: EMFs ions, electrons, molecules

8 Swing / Example of Molecular Oscillator

9 Magnetic Field Interactions with Microparticles Childhood with Leukaemia London classes only: dynamics: classical quantum variable coordinates Lorentz Force energy momentum, Energy Pumping angular momentum, spin Interference of Quantum States probabilities changed Quantum Transitions Spin Dynamics

10 Molecular Gyroscopes Arber, 1985 RF field GLU O Z C C O Binhi & Savin Molecular gyroscopes and biological effects of weak extremely lowfrequency magnetic fields Physical Review E, 65, , 2002 O - O C H C C N +

11 Interference Theory Fits Experiments MBE, arb. units Physical Review E Bioelectromagnetics Biochim. Biophys. Acta Bioelectrochem. Bioenerg. Electro &Magnetobiology 4 2 Lednev et al, 1996b, 1 H Binhi, 1997, theory α H AC /H DC Liboff et al, 1987, 45 Ca Ross, 1990, 40 Ca and Garcia-Sancho et al, 1994, 42 K Prato et al, 1995, 40 Ca 24 Mg and 40 Ca, Lednev et al, 1996a Blackman et al, 1994/5, 7 Li, α=1.8 Trillo et al, 1996, 1 H, α=2 Blackman et al, 1999, 1 H, α=2 1 0 P (theory), arb. units

12 Childhood with Leukaemia London 2004 Comparative properties of the MBE models

13 State of the Art in Theoretical Magnetobiology after 20-year investigations 1. Many models of nonthermal effects have appeared 2. They are generalized in a few theories 3. The thesis is proven to be unfounded that EMF nonthermal effects conflict with physical laws 4. Results of theoretical magnetobiology cannot be disproven now or in the future 5. The nature of nonthermal effects is as yet unknown

14 Biological Effects of Hyperweak Magnetic Fields

15 Beyond Traditional Physics

16 Fields of Changed Geometry mass Gravitational Field charge Electromagnetic Field spin?? There are two ways to describe gravity FIELD IN SPACE SPACE CHANGED Gravitational Field Curved Space (GRT)?? Twisted Space

17 Generators

18 Similarity of MBE and Development of Cancer Effects are not very predictable Very small doses may be effective Often, effects depend on field intensities or chemical concentrations in a complicated non-linear manner Slow development of effects Informational type of effects Nonthermal effects are observed most reliably at the cell level and higher, intensive DNA-RNA processes are essential Only some of the organisms in the same ensemble will show the effect For a long time the nature of both phenomena has remained unclear

19 Is there a connection? Magneto Biological Effect Cancer Time-Space Geometry

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23 Welcome to the International Scientific Conference for Childhood Leukaemia incidence causal mechanisms prevention