Network Young Membrains (NYM14) Permeation through NF and UF membranes
|
|
- Joanna Goodman
- 5 years ago
- Views:
Transcription
1 Network Young Membrains (NYM14) Permeation through NF and UF membranes Patrizia Marchetti/ Lonza Ltd/ Imperial College London (UK), September 2012
2 Transport mechanisms through membranes no pores pore dimension RO NF UF MF NF mechanism Convection / Sieving Electrostatic interactions (in H 2 O) (Diffusion) Surface interactions: hydrophilicity / hydrophobicity, polarity,... UF mechanism Convection / Sieving Electrostatic interactions (in H 2 O) sieving surface interactions slide 2
3 Outline 1. Solvent permeation solvent membrane interactions improved phenomenological model 2. Solute permeation additional interactions: solute solvent + solute membrane industrial case study: peptide in ACN / water by Design of Experiments (DoE) solute solvent membrane solvent membrane slide 3
4 Solvent permeation (1) Membrane MWCO [Da] d p [nm] Inopor Nano Inopor Nano Sulzer Inopor Ultra Hagen-Poiseuille model (viscous flow) L = P K HP µ good for UF failed for NF slide 4
5 Solvent permeation (2) Non-purely viscous flow for the solvent in NF: viscosity as main mechanism experimental points scattered around the viscous behaviour scatter (+ or -) given by surface interactions slide 5
6 Model development 1 μ as main influencing parameter K HP L P = 1+ µ Hagen-Poiseuille-type constant ( f ) C f C as correction factor (function of interaction parameters) Laplace term Dipole term Steric term f C = C 1 2 γ LV cosθθ + r p C 2 2 from Washburn equation r for capillary rise in s nanotubes δ k + pol C3 r p model parameters θ θ J v > flux < flux > flux < flux 1 Marchetti P., Buttè A., Livingston A.G., An improved phenomenological model for solvent permeation through NF and UF membranes, J.Membr. Sci., (2012) slide 6 J v
7 Prediction of pure solvent permeability Lp [l m -2.h -1.bar -1 ] Inopor Nano 750 Da experimental proposed model K µ HP L P = 1+ ( f ) L p linear vs. (1 + f C ) μ -1 C water ACN ethanol DMF regressed toluene methanol solvent NMP isopropanol acetone THF predicted DMSO Model parameters (K HP, C 1, C 2 and C 3 ) regressed on data for permeation of five solvents Predictive capability tested on data for six further solvents Good regression & prediction for both NF and UF slide 7
8 Prediction of solvent mixture permeability μ again the most influencing factor K ( f ) HP L P, MIX = 1+ C, MIX µ MIX f C dependent on the composition ( xi ) fc j f C, MIX = xi fc, i + 1, good predictions for both aqueous and organic mixtures in the NF range singular exception of ACN / water slide 8
9 ACN/water mixture: the steric term micro-heterogeneity region formation of some complexes between ACN and water 1 : CH 3 CN 2 H 2 O 2 CH 3 CN 3 H 2 O modification of r s = r s (%m ACN) CH 3 CN H 2 O 2 CH 3 CN H 2 O f C = C 1 2 γ LV cosθ + C r p 2 δ k pol + C negligible variation in the UF range 3 r r ( unmodified steric term; modified steric term) s p 2 significant improvement in the NF range ( unmodified steric term; modified steric term) 1 Kinart C.M., Kinart W.J., Kolasinski A., Acetonitryle water binary mixtures and their assumed internal structures, Phys. Chem. Liq. 35 (1997) slide 9
10 Organic Solvent NF / UF in peptide industry Peptides: Therapeutic Active Pharmaceutical Ingredients (APIs) Synthesis and intermediate + final purifications in organic solvents / solvent mixtures Ceramic NF and UF: Concentration, purification, salt / solvent exchange (diafiltration) Understanding / modelling peptide rejection: Fundamental modelling: transport mechanism has to be known Statistical modelling: practical tool for efficient lab screening + qualitative insight into the process slide 10
11 Statistical modelling: Design of Experiments (DoE) planned approach for determining cause and effect relationships 1 Main features: simultaneous variation of all potential influencing factors randomization, replication reduction or minimization of the total number of trials (compared to one factor-at-a-time) information compactness (low number of graphs and tables) polynomial degree, approximation quality 1 Z. R. Lazic, Design of Experiments in Chemical Engineering, (2004) WILEY-VCH Verlag GmbH &Co. KGaA, Weinheim slide 11
12 Case study by DoE DoE experimental set (Fractional Factorial Design FRFE): PEP 1 ~ 3000 Da, 20 amino acids, pi = 3.7 / + + concentration + solvent exchange in ACN / water Inopor Nano 750 Da, TiO 2 / Al 2 O 3, d p = 1 nm PEP 1 Name High level High level C peptide [g/l] 1 5 %v TFA %v ACN 0 30 Pressure [bar] 2 10 Pump frequency [Hz] (linear velocity [m/s]) 25 (2) 45 (4) only 19 experiments required to study the effect of 5 operating parameters! slide 12
13 Responses: solvent flux and peptide rejection regression and correlation analysis - by Analysis Of Variance (ANOVA), Design Expert Solvent flux (4 to 55 l m -2 h -1 ) Rejection (83 to 99.8%) single effects interaction effects single effects interaction effects normalized effect: regression coefficient of polynomial models for coded factors (upper level = +1; lower level = -1) slide 13
14 Physical interpretation of statistical models (1) Single effects Interaction effects Flux Rejection C p (-) C p (+) P (+) P (n.s.) Pump freq. (+) Pump freq. (+,n.s.) %v TFA (+) %v TFA (+) %v ACN (+) %v ACN (+) C p %v TFA (+) C p %v TFA (-) C p - %v ACN (+) C p - %v ACN (-) %v TFA - %v ACN(-) P Pump freq. (+) 1) solute membrane: direct effect on solute passage 2) solvent solute membrane: solvent effect on solute passage solvent n.s. = non significant solute membrane slide 14
15 Physical interpretation of statistical models (2) 1) Solute membrane interactions: C p has negative effect on flux and positive on rej.: adsorption / accumulation ads. layer Single effects Interaction effects Flux Rejection C p (-) C p (+) P (+) n.s. = non significant Pump freq. (+) P (n.s.) Pump freq. (+,n.s.) %v TFA (+) %v TFA (+) %v ACN (+) %v ACN (+) C p %v TFA (+) C p %v TFA (-) C p - %v ACN (+) C p - %v ACN (-) %v TFA - %v ACN(-) P Pump freq. (+) J v J v d p d p P has a positive effect on flux and no significant effect on rej. Pump freq. ( u B ) has positive effect on flux and rej. ads. layer d p d p fast u B slow u B slide 15
16 Physical interpretation of statistical models (3) 2) Solvent solute membrane interactions: Single effects Interaction effects Flux Rejection C p (-) C p (+) P (+) P (n.s.) Pump freq. (+) Pump freq. (+,n.s.) %v TFA (+) %v TFA (+) %v ACN (+) %v ACN (+) C p %v TFA (+) C p %v TFA (-) C p - %v ACN (+) C p - %v ACN (-) %v TFA - %v ACN(-) P Pump freq. (+) %v TFA and %v ACN have positive effect on both flux and rej.: increase molecular size and hydrophobicity TFA TFA TFA TFA TFA TFA TFA TFA > friction J s < friction < flux J v > flux J s J v n.s. = non significant J s = solute flux; J v = solvent flux slide 16
17 Summary of ternary interactions μ, γ LV, δ s, r solvent peptide case-study described by statistical model (DoE) physical interpretation of statistical model solvent permeation of pure solvent and solvent mixture through ceramic NF and UF membranes described by phenomenological model solute r solute, pi, hydrophilicity C solute, P, Hz (u solvent ) membrane γ SV, k pol, r p, pi slide 17
18 Acknowledgements Dr. Alessandro Butté, Lonza Ltd (Visp, CH) Prof. Andrew G. Livingston, Imperial College London (London, UK) NEMOPUR project, Marie Curie ITN, FP7 slide 18
19 Thank You Questions slide 19
20 ACN/water mixture 1: water-rich region 3: ACN-rich region (Graph from Kinart et al. 2 ) Hypothesis: parabolic distribution of r s in function of the composition region 2 region 1 region 3 2: micro-heterogeneity region 1 formation of some complexes between ACN and water 2 : CH 3 CN 2 H 2 O 2 CH 3 CN 3 H 2 O CH 3 CN H 2 O 2 CH 3 CN H 2 O f C = C 1 2 γ LV cosθ + C r p 2 δ k pol + C 3 r r s p 2 1 Moreau C., Douhéret G., Thermodynamic behavior of water-acetonitrile mixtures, Thermochimica Acta 13 (1975) Kinart C.M., Kinart W.J., Kolasinski A., Acetonitryle water binary mixtures and their assumed internal structures, Physics and Chemistry of Liquids 35 (1997) slide 20
21 k pol = 2 γ γ p SV p LV cosθ = 2 γ d SV + k pol γ γ p LV d LV γ γ d LV LV 1 slide 21
22 Meaning of interaction effects the combined change in two factors that produces an effect greater (or less) than the additive effect expected from the factors alone No interaction: z = x + y z x y Antagonistic interaction: z = x + y - x y x y Synergistic interaction: z = x + y + x y z z x y slide 22
23 Outline Introduction Transport mechanism through NF and UF membranes Solvent permeation solvent solvent membrane interactions improved phenomenological model Solute permeation additional interactions: solute solvent + solute membrane industrial case study: peptide in ACN / water by DoE membrane solvent Conclusions solute membrane slide 23
24 Conclusions An improved model was proposed to: describe permeation of pure solvent and solvent mixture through ceramic NF and UF membranes describe solvent-membrane interactions The permeation of one case-study peptide was: studied by DoE, as reliable investigation strategy at lab scale described by physical interpretation of statistical models Classification and identification of ternary interactions: can help fundamental modelling for complicated molecules, like peptides slide 24
25 DoE: Factorial designs First-order mathematical model: Yˆ = b0 + k i b i X i + k i b ij X i X j response value estimated constants for single effects estimated constants for interaction effects independent parameters Design experiment of type 2k: 2 = number of levels; k = number of parameters Orthogonal matrix For k = 3: slide 25
26 DoE: Response Surface Model (RSM) Second-order mathematical model: Yˆ = b0 k + b i i X i k + a i i X 2 i + k b ij i X i X j response value estimated constants for firstorder single effects estimated constants for secondorder single effects estimated constants for interaction effects independent parameters Computer aided design (D-optimal design) with the best subset of all possible experiments Non orthogonal matrix of design points slide 26
27 DoE: data collection and analysis For 5 factors: FRFE: 16 experiments + 4 center points linear model 2FI (factorial) model D-Optimal: 28 experiments + with 6 center points linear model 2FI (factorial) model quadratic model (FUFE: 3 5 = 243 experiments) Factor A B C D E Name C peptide [g/l] ph Pressure (P) [bar] Pump frequency [Hz] %v ACN slide 27
Solvent flux behaviour and rejection characteristics of hydrophilic and hydrophobic TiO2 and ZrO2 membranes
Solvent flux behaviour and rejection characteristics of hydrophilic and hydrophobic TiO2 and ZrO2 membranes Dobrak A.1, Verrecht B.1,2, Van den Dungen H.1, Leysen R.2, Buekenhoudt A.2, Van der Bruggen
More informationChapter 3 Membrane Processes for Water Production
Chapter 3 Membrane Processes for Water Production Application of Membrane Processes in Water Environment Fusion Tech Hydrology Molecular biology Surface Chem Nano particles Biofilm CFD Catalyst Space station
More informationContents. Preface XI Symbols and Abbreviations XIII. 1 Introduction 1
V Contents Preface XI Symbols and Abbreviations XIII 1 Introduction 1 2 Van der Waals Forces 5 2.1 Van der Waals Forces Between Molecules 5 2.1.1 Coulomb Interaction 5 2.1.2 Monopole Dipole Interaction
More information10 Chemical reactions in aqueous solutions
The Physics and Chemistry of Water 10 Chemical reactions in aqueous solutions Effects of water in reactions Hydration of reactants cause steric barriers Increases attraction between nonpolar reactants
More informationHow proteins separate on reverse-phase HPLC
1 Reverse Phase How proteins separate on reverse-phase HPLC RP chromatography separates proteins through the interaction of the hydrophobic foot of the protein with a nonpolar surface of the particle RP
More informationLC and LC/MS Column Selection Flow Chart
LC and LC/MS Column Selection Flow Chart To use the column selection diagram below, simply follow the path for your analyte and mobile phase. At the far right, follow your final column selection to the
More informationMembrane processes selective hydromechanical diffusion-based porous nonporous
Membrane processes Separation of liquid or gaseous mixtures by mass transport through membrane (= permeation). Membrane is selective, i.e. it has different permeability for different components. Conditions
More informationD-MAVT Membrane Separation Processes
Membrane Separation Processes Federico Milella Rate Controlled Separation - Autumn 2017 Separation Processes Laboratory - Institute of Process Engineering Agenda Introduction Mass balances over a membrane
More informationLiquid-vapour oscillations of water in hydrophobic nanopores
Alicante 2003 4th European Biophysics Congress Liquid-vapour oscillations of water in hydrophobic nanopores 7 th July 2003 Oliver Beckstein and Mark S. P. Sansom Department of Biochemistry, Laboratory
More informationLIQUID CHROMATOGRAPHY
LIQUID CHROMATOGRAPHY RECENT TECHNIQUES HPLC High Performance Liquid Chromatography RRLC Rapid Resolution Liquid Chromatography UPLC Ultra Performance Liquid Chromatography UHPLC Ultra High Pressure Liquid
More informationMutual diffusion in the ternary mixture of water + methanol + ethanol: Experiments and Molecular Simulation
- 1 - Mutual diffusion in the ternary mixture of water + methanol + ethanol: Experiments and Molecular Simulation Tatjana Janzen, Gabriela Guevara-Carrión, Jadran Vrabec University of Paderborn, Germany
More informationSeparation Performance of Polymer Membranes for Organic Solvent Mixtures
A publication of 1885 CHEMICAL ENGINEERING TRANSACTIONS VOL. 32, 2013 Chief Editors: Sauro Pierucci, Jiří J. Klemeš Copyright 2013, AIDIC Servizi S.r.l., ISBN 978-88-95608-23-5; ISSN 1974-9791 The Italian
More informationInvestigating the effect of graphene oxide on scaling in thin-film composite polyamide reverse osmosis membranes
Investigating the effect of graphene oxide on scaling in thin-film composite polyamide reverse osmosis membranes Ali Ansari, Bo Cao, Xinyi Yi, Yandi Hu, and Debora Rodrigues Civil and Environmental Engineering,
More informationOpen Column Chromatography, GC, TLC, and HPLC
Open Column Chromatography, GC, TLC, and HPLC Murphy, B. (2017). Introduction to Chromatography: Lecture 1. Lecture presented at PHAR 423 Lecture in UIC College of Pharmacy, Chicago. USES OF CHROMATOGRAPHY
More informationDEPARTMENT OF POLYMER AND PROCESS ENGINEERING (http://www.uet.edu.pk/polymer.htm)
DEPARTMENT OF POLYMER AND PROCESS ENGINEERING (http://www.uet.edu.pk/polymer.htm) Programs Offered The Department offers the following degree programmes a) M.Sc. Polymer and Process Engineering b) Ph.D.
More information1 Introduction to membrane filtration of liquids
1 Introduction to membrane filtration of liquids 1.1 Introduction This book is largely concerned with solving process problems in the membrane filtration of liquids. In that sense, it is more a chemical
More informationPREDICTION OF NANOFILTRATION MEMBRANE PERFORMANCE: ANALYSIS OF ION TRANSPORT MECHANISMS
PREDICTION OF NANOFILTRATION MEMBRANE PERFORMANCE: ANALYSIS OF ION TRANSPORT MECHANISMS Norhaslina Mohd Sidek 1, Sarifah Fauziah Syed Draman 1, Nora aini Ali 2 and Ilyani Abdullah 3 1 Faculty of Chemical
More informationUltraltration Membrane Separation of Coee
Ultraltration Membrane Separation of Coee Ole Håvik Bjørkedal olehb@stud.ntnu.no Therese Bache theresba@stud.ntnu.no October 31, 2013 Abstract This experiment was performed as part of the TKP4105/TKP4110
More informationHPLC Background Chem 250 F 2008 Page 1 of 24
HPLC Background Chem 250 F 2008 Page 1 of 24 Outline: General and descriptive aspects of chromatographic retention and separation: phenomenological k, efficiency, selectivity. Quantitative description
More informationPhysics and Chemistry of Interfaces
Hans Jürgen Butt, Karlheinz Graf, and Michael Kappl Physics and Chemistry of Interfaces Second, Revised and Enlarged Edition WILEY- VCH WILEY-VCH Verlag GmbH & Co. KGaA Contents Preface XI 1 Introduction
More informationChemistry Instrumental Analysis Lecture 28. Chem 4631
Chemistry 4631 Instrumental Analysis Lecture 28 High Performance Liquid Chromatography () Instrumentation Normal Phase Chromatography Normal Phase - a polar stationary phase with a less polar mobile phase.
More informationInvestigation of Mixed Gas Sorption in Lab-Scale. Dr. Andreas Möller
Investigation of Mixed Gas Sorption in Lab-Scale Dr. Andreas Möller 1 Technical Necessity: Application of porous Materials as Adsorbents Fine cleaning of Gases (i.e. purification of H 2, natural gas, bio
More informationPrinciples of Electrochemistry Second Edition
Principles of Electrochemistry Second Edition Jiri Koryta Institute of Physiology, Czechoslovak Academy of Sciences, Prague HKJin Dvorak Department of Physical Chemistry, Faculty of Science, Charles University,
More informationCHEM 429 / 529 Chemical Separation Techniques
CHEM 429 / 529 Chemical Separation Techniques Robert E. Synovec, Professor Department of Chemistry University of Washington Lecture 1 Course Introduction Goal Chromatography and Related Techniques Obtain
More informationDesign of Engineering Experiments Chapter 5 Introduction to Factorials
Design of Engineering Experiments Chapter 5 Introduction to Factorials Text reference, Chapter 5 page 170 General principles of factorial experiments The two-factor factorial with fixed effects The ANOVA
More informationChapter 5. Transport in Membrane
National October 7, 2015 (Wed) Chang-Han Yun / Ph.D. Contents 5.1 Introduction 5.2 Driving Forces Contents Contents 5.3 Non-equilibrium Thermodynamics 5.4 Transport through Porous Membranes 5.5 Transport
More informationHarris: Quantitative Chemical Analysis, Eight Edition CHAPTER 25: CHROMATOGRAPHIC METHODS AND CAPILLARY ELECTROPHORESIS
Harris: Quantitative Chemical Analysis, Eight Edition CHAPTER 25: CHROMATOGRAPHIC METHODS AND CAPILLARY ELECTROPHORESIS CHAPTER 25: Opener Aa CHAPTER 25: Opener Ab CHAPTER 25: Opener B 25-1 Ion-Exchange
More informationCENG 5210 Advanced Separation Processes. Reverse osmosis
Reverse osmosis CENG 510 Advanced Separation Processes In osmosis, solvent transports from a dilute solute or salt solution to a concentrated solute or salt solution across a semipermeable membrane hich
More informationEvaluation of apparent and partial molar volume of potassium ferro- and ferricyanides in aqueous alcohol solutions at different temperatures
Indian Journal of Chemical Technology ol. 11, September 4, pp. 714-718 Evaluation of apparent and partial molar volume of potassium ferro- and ferricyanides in aqueous alcohol solutions at different temperatures
More informationBasic Principles of Membrane Technolog
Basic Principles of Membrane Technolog by Marcel Mulder Center for Membrane Science and Technology, University oftwente, Enschede, The Netherlands ff KLUWER ACADEMIC PUBLISHERS DORDRECHT / BOSTON / LONDON
More informationMicrofiltration,Ultrafiltration, and
HATER 3 Microfiltration,Ultrafiltration, and Nanofiltration ti Models for redicting Flux for MF, UF and NF 1) apillary Model 2) Film Theory Model 3) Flux aradox (back-transport) 4) Resistance in series
More informationSupporting Information
Electronic Supplementary Material (ESI) for Dalton Transactions. This journal is The Royal Society of Chemistry 2014 Supporting Information Unraveling the Origins of Catalyst Degradation in Non-heme Ironbased
More informationSupporting Information
Supporting Information Tuning Supramolecular Structure and Functions of Peptide bola-amphiphile by Solvent Evaporation-Dissolution Anhe Wang,, Lingyun Cui,, Sisir Debnath, Qianqian Dong, Xuehai Yan, Xi
More informationLATEST TECHNOLOGY IN Safe handling & Recovery OF Solvents in Pharma Industry
LATEST TECHNOLOGY IN Safe handling & Recovery OF Solvents in Pharma Industry TYPICAL SOLVENT USE IN Pharma Industry Usage of solvents in an API process development is for: Diluent to carry out reaction
More informationLecture 4 : Gel Permeation or Size Exclusion Chromatography
Lecture 4 : Gel Permeation or Size Exclusion Chromatography Polymer Fractionation Sedimentation Centrifugation Evaporation of the solvent Gel permeation chromatography Gel Permeation Chromatography (GPC)
More informationPolymers Reactions and Polymers Production (3 rd cycle)
EQ, Q, DEQuim, DQuim nd semester 017/018, IST-UL Science and Technology of Polymers ( nd cycle) Polymers Reactions and Polymers Production (3 rd cycle) Lecture 5 Viscosity easurements of the viscosity
More informationFriction Coefficient Analysis of Multicomponent Solute Transport Through Polymer Membranes
Friction Coefficient Analysis of Multicomponent Solute Transport Through Polymer Membranes NARASIMHAN SUNDARAM NIKOLAOS A. PEPPAS* School of Chemical Engineering, Purdue University, West Lafayette, Indiana
More informationQuick guide to selecting columns and standards for Gel Permeation Chromatography and Size Exclusion Chromatography SELECTION GUIDE
Quick guide to selecting columns and standards for Gel Permeation Chromatography and Size Exclusion Chromatography SELECTION GUIDE Introduction Gel permeation chromatography (GPC) and size exclusion chromatography
More informationZEOLITES AS ALCOHOL ADSORBENTS FROM AQUEOUS SOLUTIONS
UDC 661.183.6:66.021.3.081.3:547.260.2 APTEFF, 37, 1-192 (2006) BIBLID: 1450 7188 (2006) 37, 83-87 Original scientific paper ZEOLITES AS ALCOHOL ADSORBENTS FROM AQUEOUS SOLUTIONS Blagica Cekova, Dragi
More informationAqueous Self-Assembly of Fp Derivatives: Multifunctional Metal-Carbonyl Nanovesicles (MCsomes)
Aqueous Self-Assembly of Fp Derivatives: Multifunctional Metal-Carbonyl Nanovesicles (MCsomes) 38 th IPR Symposium-May 4 th 2016 Nimer Murshid and Xiaosong Wang Nimer Murshid Department of Chemistry Waterloo
More informationA Systematic Approach towards Synthesis and Design of Pervaporation-Assisted Separation Processes
1534 Research Article Chemie A Systematic Approach towards Synthesis and Design of Pervaporation-Assisted Separation Processes Bettina Scharzec, Thomas Waltermann, and Mirko Skiborowski* DOI: 10.1002/cite.201700079
More informationSupporting information
Electronic Supplementary Material (ESI) for Green Chemistry. This journal is The Royal Society of Chemistry 2016 Supporting information From alcohol to 1,2,3-triazole via multi-step continuous-flow synthesis
More informationMutual diffusion of binary liquid mixtures containing methanol, ethanol, acetone, benzene, cyclohexane, toluene and carbon tetrachloride
- 1 - PLMMP 2016, Kyiv Mutual diffusion of binary liquid mixtures containing methanol, ethanol, acetone, benzene, cyclohexane, toluene and carbon tetrachloride Jadran Vrabec Tatjana Janzen, Gabriela Guevara-Carrión,
More informationGel Permeation Chromatography - GPC
Isolation and Separation Methods J. Poustka, VŠCHT Praha, ÚAPV 2014, http://web.vscht.cz/poustkaj Gel Permeation Chromatography - GPC Separation and clean-up method Group separation of compounds with similar
More informationInternational Journal of Advancements in Research & Technology, Volume 3, Issue 11, November ISSN
International Journal of Advancements in Research & Technology, Volume 3, Issue 11, November -2014 30 HEAT TRANSFER INTENSIFICATION USING NANOFLUIDS INTRODUCTION Prof. B.N. Havaraddi Assistant Professor
More informationFelleslab ST-7 Ultrafiltration Group B-16
Ultrafiltration Yngve Mannsåker Hereide yngvemh@stud.ntnu.no Åge Johansen agej@stud.ntnu.no Abstract ii Contents 1 Introduction 1 2 Theory 1 3 Experimental 2 3.1 Experimental Setup...................
More informationMathematical Modeling and Simulation
Kai Velten Mathematical Modeling and Simulation Introduction for Scientists ar d Engineers WILLYNCH Verlag (irribli & Co. l
More informationHPLC COLUMNS WILEY-VCH. Theory, Technology, and Practice. Uwe D. Neue with a contribution from M. Zoubair El Fallah
HPLC COLUMNS Theory, Technology, and Practice Uwe D. Neue with a contribution from M. Zoubair El Fallah WILEY-VCH New York Chichester Weinheim Brisbane Singapore Toronto CONTENTS Preface ix 1 Introduction
More informationChemical Reaction Engineering Prof. Jayant Modak Department of Chemical Engineering Indian Institute of Science, Bangalore
Chemical Reaction Engineering Prof. Jayant Modak Department of Chemical Engineering Indian Institute of Science, Bangalore Lecture No. # 26 Problem solving : Heterogeneous reactions Friends, in last few
More informationSEPARATIONS ESSENTIALS IN MODERN HPLC. 2University of Bucharest, Bucharest, Romania
ESSENTIALS IN MODERN HPLC SEPARATIONS Serban C. Moldoveanu1, Victor David2 'R.J. Reynolds Tobacco Co., Winston-Salem, NC, USA 2University of Bucharest, Bucharest, Romania ELSEVIER AMSTERDAM BOSTON HEIDELBERG
More informationDesign & Analysis of Experiments 7E 2009 Montgomery
Chapter 5 1 Introduction to Factorial Design Study the effects of 2 or more factors All possible combinations of factor levels are investigated For example, if there are a levels of factor A and b levels
More informationOptimization of Methane Conversion to Liquid Fuels over W-Cu/ZSM5 Catalysts by Response Surface Methodology
Diponegoro University From the SelectedWorks of Istadi May 12, 2008 Optimization of Methane Conversion to Liquid Fuels over W-Cu/ZSM5 Catalysts by Response Surface Methodology Istadi Istadi, Diponegoro
More informationProtein separation and characterization
Address:800 S Wineville Avenue, Ontario, CA 91761,USA Website:www.aladdin-e.com Email USA: tech@aladdin-e.com Email EU: eutech@aladdin-e.com Email Asia Pacific: cntech@aladdin-e.com Protein separation
More informationExperiment and Simulation Study of Multi-component Gas Adsorption On MSC3A By Volumetric method
Experiment and Simulation Study of Multi-component Gas Adsorption On MSC3A By Volumetric method Kazuyuki. Chihara, Shohei. Koide, Masashi Nomoto, Yuzo. Amari, Meiji University,Kawasaki,Japan Abstruct Equilibria
More informationQSARs for trace organics removal by activated carbon and membrane filtration
Transnational Action Program on Emerging Substances QSARs for trace organics removal by activated carbon and membrane filtration On the sense and non-sense of QSARs for these processes www.tapes-interreg.eu
More informationOrganic Contaminant Removal and Membrane Fouling
Advanced Membrane Technologies Stanford University, May 07, 2008 Organic Contaminant Removal and Membrane Fouling Martin Reinhard Eva Steinle-Darling, Megan Plumlee, Federico Pacheco, Yi-li Lin Civil and
More informationCFD STUDY OF MASS TRANSFER IN SPACER FILLED MEMBRANE MODULE
GANIT J. Bangladesh Math. Soc. (ISSN 1606-3694) 31 (2011) 33-41 CFD STUDY OF MASS TRANSFER IN SPACER FILLED MEMBRANE MODULE Sharmina Hussain Department of Mathematics and Natural Science BRAC University,
More informationInterface Location of Capillary Driven Flow in Circular Micro Channel Using by COMSOL
Interface Location of Capillary Driven Flow in Circular Micro Channel Using by COMSOL ARSHYA BAMSHAD 1, MOHAMMAD H. SABOUR 2, ALIREZA NIKFARJAM 3 Faculty of New Sciences & Technologies University of Tehran
More informationSupporting Information
Supporting Information Interface-Induced Affinity Sieving in Nanoporous Graphenes for Liquid-Phase Mixtures Yanan Hou, Zhijun Xu, Xiaoning Yang * State Key Laboratory of Material-Orientated Chemical Engineering,
More informationSupporting Information
Supporting Information Copyright Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, 2016 Reanalysis of the Much Referenced Ethanol-trichloromethane Mixture Vapor Pressure Data: A Discussion of the Principal
More informationSUPPORTING INFORMATION. Framework and Extraframework Tin Sites in Zeolite Beta React Glucose Differently
SUPPORTING INFORMATION Framework and Extraframework Tin Sites in Zeolite Beta React Glucose Differently Ricardo Bermejo-Deval, Rajamani Gounder and Mark E. Davis* Chemical Engineering, California Institute
More informationSupporting Information
Supporting Information Copyright Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, 2013 ph-controlled Reversible Formation of a Supramolecular Hyperbranched Polymer Showing Fluorescence Switching Bingran
More informationAcoustical Studies on Binary Liquid Mixture of Methylmethacrylate in 1, 4-Dioxane at 303 K Temperature
International Journal of Advanced Research in Physical Science (IJARPS) Volume 1, Issue 5, September 2014, PP 1-5 ISSN 2349-7874 (Print) & ISSN 2349-7882 (Online) www.arcjournals.org Acoustical Studies
More informationLIMITING IONIC PARTIAL MOLAR VOLUMES OF R 4 N + AND I IN AQUEOUS METHANOL AT K
Int. J. Chem. Sci.: 11(1), 2013, 321-330 ISSN 0972-768X www.sadgurupublications.com LIMITING IONIC PARTIAL MOLAR VOLUMES OF R 4 N + AND I IN AQUEOUS METHANOL AT 298.15 K N. P. NIKAM * and S. V. PATIL a
More informationA dispersion (system) Colloidal solutions High molecular mass compounds
A dispersion (system) Colloidal solutions High molecular mass compounds Outline Types of dispersions Characteristics of main types of dispersions Properties of colloidal solutions Structure of colloidal
More informationNanofiltration properties of PTMSP in binary organic solvents mixtures
Journal of Physics: Conference Series PAPER OPEN ACCESS Nanofiltration properties of PTMSP in binary organic solvents mixtures To cite this article: A A Yushkin et al 2016 J. Phys.: Conf. Ser. 751 012044
More informationTechnical data and operating instructions. Vivaspin 4. Vivaspin 4 10K device for in vitro diagnostic use
Technical data and operating instructions Vivaspin 4 Vivaspin 4 10K device for in vitro diagnostic use 85030-516-16 85030-516-16 Vivaspin 4 ml Introduction Storage conditions shelf life Vivaspin 4 ultrafiltration
More informationULTRAFLITRATION OF WASTEWATER WITH PRETREATMENT: EVALUATION OF FLUX DECLINE MODELS
ULTRAFLITRATION OF WASTEWATER WITH PRETREATMENT: EVALUATION OF FLUX DECLINE MODELS H. K. Shon, S. Vigneswaran,* J. Kandasamy and W.G. Shim 2 Faculty of Engineering, University of Technology, Sydney, P.O.
More informationPhysical Chemistry of Polymers (4)
Physical Chemistry of Polymers (4) Dr. Z. Maghsoud CONCENTRATED SOLUTIONS, PHASE SEPARATION BEHAVIOR, AND DIFFUSION A wide range of modern research as well as a variety of engineering applications exist
More informationMeasurement and Prediction of Speed of Sound in Petroleum Fluids
Vol:, No:9, 27 Measurement and Prediction of Speed of Sound in Petroleum Fluids S. Ghafoori, A. Al-Harbi, B. Al-Ajmi, A. Al-Shaalan, A. Al-Ajmi, M. Ali Juma Digital Open Science Index, Energy and Power
More informationINTRODUCTORY CHEMISTRY FOR WATER QUALITY TECHNOLOGY I. Chemistry 11 and Principles of Mathematics 12 is strongly recommended.
CHEMISTRY 115 INTRODUCTORY CHEMISTRY FOR WATER QUALITY TECHNOLOGY I Prerequisites: Format: Chemistry 11 and Principles of Mathematics 12 is strongly recommended. 4 hours lecture + 3 hours lab per week
More informationAnalytical Chemistry
Analytical Chemistry Chromatographic Separations KAM021 2016 Dr. A. Jesorka, 6112, aldo@chalmers.se Introduction to Chromatographic Separations Theory of Separations -Chromatography Terms Summary: Chromatography
More informationAalborg Universitet. Transport phenomena in gas-selective silica membranes Boffa, Vittorio. Creative Commons License Unspecified
Aalborg Universitet Transport phenomena in gas-selective silica membranes Boffa, Vittorio Creative Commons License Unspecified Publication date: 2016 Link to publication from Aalborg University Citation
More informationComparative Study of Molecular Interaction in Ternary Liquid Mixtures of Polar and Non-Polar Solvents by Ultrasonic Velocity Measurements
Comparative Study of Molecular Interaction in Ternary Liquid Mixtures of Polar and Non-Polar Solvents by Ultrasonic Velocity Measurements Manoj Kumar Praharaj 1, Sarmistha Mishra 2 Department of Physics,
More informationHybrid organic solvent nanofiltration membranes on ceramic and polymeric supports
Hybrid organic solvent nanofiltration membranes on ceramic and polymeric supports H.M. van Veen (ECN) J.P. Overbeek (ECN) M.M.A. van Tuel (ECN) F.P. Cuperus (Solsep) I.M. Wienk (Solsep) P.H.T. Ngamou (TU/e)
More informationSupplementary Information for Evaluating the. energetic driving force for co-crystal formation
Supplementary Information for Evaluating the energetic driving force for co-crystal formation Christopher R. Taylor and Graeme M. Day School of Chemistry, University of Southampton, Highfield, Southampton,
More informationHICHROM. Chromatography Columns and Supplies. LC COLUMNS SIELC Primesep. Catalogue 9. Hichrom Limited
HICHROM Chromatography Columns and Supplies LC COLUMNS SIELC Primesep Catalogue 9 The Markham Centre, Station Road Theale, Reading, Berks, RG7 4PE, UK Tel: +44 (0)8 90 660 Fax: +44 (0)8 9 484 Email: sales@hichrom.co.uk
More informationEstimate the extent of concentration polarization in crossflow filtration Select filtration unit operations to meet product requirements, consistent
Membrane Separation Process Objectives Estimate the extent of concentration polarization in crossflow filtration Select filtration unit operations to meet product requirements, consistent with product
More informationAdvanced Analytical Chemistry Lecture 19. Chem 4631
Advanced Analytical Chemistry Lecture 19 Chem 4631 Organic Electrochemistry is a multidisciplinary science overlapping the fields of organic chemistry, biochemistry, physical chemistry and electrochemistry.
More informationThermo acoustical study of tetrahydrofuran with ethanol using ultrasonic technique at 323K
Available online at www.pelagiaresearchlibrary.com Advances in Applied Science Research, 2014, 5(2):80-85 ISSN: 0976-8610 CODEN (USA): AASRFC Thermo acoustical study of tetrahydrofuran with ethanol using
More informationDiffusion and Adsorption in porous media. Ali Ahmadpour Chemical Eng. Dept. Ferdowsi University of Mashhad
Diffusion and Adsorption in porous media Ali Ahmadpour Chemical Eng. Dept. Ferdowsi University of Mashhad Contents Introduction Devices used to Measure Diffusion in Porous Solids Modes of transport in
More information2.500 Desalination and Water Purification
MIT OpenCourseWare http://ocw.mit.edu 2.500 Desalination and Water Purification Spring 2009 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms. Amphiphilic
More informationIntroduction to Nanoparticle Tracking Analysis (NTA) Measurement Principle of ZetaView
Technical Note Nanoparticle Tracking Key words: Introduction to Nanoparticle Tracking Analysis (NTA) Measurement Principle of ZetaView Particle characterization, Nanoparticle Tracking Analysis (NTA), Brownian
More informationINPHAZE HiRes-EIS High Resolution Electrical Impedance Spectroscopy. HiRes-EIS for Characterization of Membranes & Membrane Fouling
INPHAZE HiRes-EIS High Resolution Electrical Impedance Spectroscopy Abstract HiRes-EIS for Characterization of Membranes & Membrane Fouling Separation membranes typically have a thin skin layer supported
More informationThermo-acoustical molecular interaction studies in ternary liquid mixtures using ultrasonic technique at 303K
Available online at www.pelagiaresearchlibrary.com Advances in Applied Science Research, 2013, 4(2):54-59 ISSN: 0976-8610 CODEN (USA): AASRFC Thermo-acoustical molecular interaction studies in ternary
More informationPhoto-switched self-assembly of Gemini -helical peptide into supramolecular architectures
5 Electronic Supplementary Information of Photo-switched self-assembly of Gemini -helical peptide into supramolecular architectures Chang-Sheng Chen, Xiao-Ding Xu, Shi-Ying Li, Ren-Xi Zhuo, Xian-Zheng
More informationUltrasonic velocity and viscosity studies of tramacip and parvodex in binary mixtures of alcohol + water
Indian Journal of Pure & Applied Physics Vol. 46, December 2008, pp. 839-843 Ultrasonic velocity and viscosity studies of tramacip and parvodex in binary mixtures of alcohol + water Poonam Sharma*, S Chauhan,
More informationDansk Mejeriteknisk Selskab Billund, June 14th Challenges in the Dairy Industry: Perspective on extreme performance membranes
Dansk Mejeriteknisk Selskab Billund, June 14th 2018 Challenges in the Dairy Industry: Perspective on extreme performance membranes OLE LILLEVANG, TECHNOLOGY SPECIALIST GEA PRODUCT TECHNOLOGY CENTER FILTRATION
More informationChem 1075 Chapter 13 Liquids and Solids Lecture Outline
Chem 1075 Chapter 13 Liquids and Solids Lecture Outline Slide 2-3 Properties of Liquids Unlike gases, liquids respond dramatically to temperature and pressure changes. We can study the liquid state and
More informationMembrane for water reuse: effect of pre-coagulation on fouling and selectivity
Membrane for water reuse: effect of pre-coagulation on fouling and selectivity Y. Soffer*, R. Ben Aim** and A. Adin* *Division of Environmental Sciences, The Hebrew University of Jerusalem, Jerusalem 91904,
More informationEQ121 - Membrane Processes and Technologies
Coordinating unit: 295 - EEBE - Barcelona East School of Engineering Teaching unit: 713 - EQ - Department of Chemical Engineering Academic year: 2018 Degree: ECTS credits: 6 Teaching languages: English
More informationcontact line dynamics
contact line dynamics Jacco Snoeijer Physics of Fluids - University of Twente sliding drops flow near contact line static contact line Ingbrigtsen & Toxvaerd (2007) γ γ sv θ e γ sl molecular scales macroscopic
More informationCOLLIGATIVE PROPERTIES. Engr. Yvonne Ligaya F. Musico 1
COLLIGATIVE PROPERTIES Engr. Yvonne Ligaya F. Musico 1 Colligative Properties Properties that depend on the collective effect of the number of solute particles. Engr. Yvonne Ligaya F. Musico 2 COLLEGATIVE
More informationLecture 10. Membrane Separation Materials and Modules
ecture 10. Membrane Separation Materials and Modules Membrane Separation Types of Membrane Membrane Separation Operations - Microporous membrane - Dense membrane Membrane Materials Asymmetric Polymer Membrane
More informationGeneral Chemistry by Ebbing and Gammon, 9th Edition George W.J. Kenney, Jr, Professor of Chemistry Last Update: 15-May-2009
Chem 1046 General Chemistry by Ebbing and Gammon, 9th Edition George W.J. Kenney, Jr, Professor of Chemistry Last Update: 15-May-2009 Chapter 12 SOLUTIONS These Notes are to SUPPLIMENT the Text, They do
More informationThe Effect of Contact Angle and Wetting on Performance in Solid Phase Extraction
The Effect of Contact Angle and Wetting on Performance in Solid Phase Extraction Edouard S. P. Bouvier, Randy E. Meirowitz and Uwe D. Neue Waters Corporation, 34 Maple Street, Milford, MA 01757 USA Presented
More informationHigh Resolution Laser Microscopy: a fascinating method to explore the molecular world
High Resolution Laser Microscopy: a fascinating method to explore the molecular world Alfred J. Meixner Physical and Theoretical Chemistry Laboratory University of Siegen Single-molecule spectroscopy and
More informationSupporting Information. Copyright Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2007
Supporting Information Copyright Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, 2007 Copyright Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, 2007 Supporting Information for Head-to-Tail Cyclized
More informationPERMEATION OF SUPERCRITICAL CARBON DIOXIDE ACROSS POLYMERIC HOLLOW FIBER MEMBRANES
PERMEATION OF SUPERCRITICAL CARBON DIOXIDE ACROSS POLYMERIC HOLLOW FIBER MEMBRANES V. E. Patil* 1, L. J. P. van den Broeke 1, F. Vercauteren and J.T.F. Keurentjes 1 1 Department of Chemistry and Chemical
More informationMaterials development for inorganic membrane layers at ECN
Materials development for inorganic membrane layers at ECN B.C. Bonekamp Presented at XXV EMS Summerschool, Leuven, Belgium, September ECN-M--09-062 May Materials Development for Inorganic Membrane Layers
More information