HumaStar 100 HumaStar 200
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- Louise Sharp
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1 HumaStar 100 HumaStar 200 Key advantages Competition Product features Rev. 08d
2 Scope of supply The slides provided in this section are concerned with availability, scope of supply and registration of the products.
3 Scope of delivery Included: Not included: Instrument UPS Computer & Monitor (necessary for operation) Printer Accessory Kit Wash Solutions (necessary for operation) Wash Add Special Wash Solution (NaOH) Cuvette Clean (turbidimetry) Page 5
4 Page 18 Key advantages at a glance
5 Reliable results and flexibility Reagents and instruments from one supplier Reliable results HUMAN methods pre-installed and validated Reagent cooling Reliable results, less application work, less supports, less cost Flexibility (Open analyzer) Substrates, enzymes, turbidimetry, electrolytes Flexible to use other reagents Page 19
6 Reliable methods More testing than for any other open instrument Validation on 4 analyzers running for almost 1 year More than tests Recovery (8 different controls) Precision (intra-assay and inter-assay 5 days, 3 levels for each) Limit of linearity Limit of detection Calibration stability Onboard stability Method comparison (internal and/or external AU400) Page 20
7 Pre-installed methods The laboratory has reliable results without doing any application work by themselves. Page 21
8 Clinical Chemistry ACID PHOSPHATASE HbA1c liquidirect ALBUMIN liquicolor HDL CHOLESTEROL liquicolor ALKALINE PHOSPHATASE liquicolor HOMOCYSTEINE liquiuv ALKALINE PHOSPHATASE opt. liquicolor IRON liquicolor alpha-amylase liquicolor IRON TPTZ liquicolor auto-bilirubin-d liquicolor LDH SCE mod. liquiuv auto-bilirubin-t liquicolor LDL CHOLESTEROL liquicolor auto-creatinine liquicolor LIPASE liquicolor CALCIUM liquicolor MAGNESIUM liquicolor CHLORIDE liquicolor PANCREAS-AMYLASE liquicolor CHOLESTEROL liquicolor PHOSPHORUS liquirapid CK NAC liquiuv POTASSIUM liquiuv CK-MB liquiuv SODIUM liquicolor CREATININE (enzym) liquicolor TOTAL PROTEIN liquicolor gamma-gt liquicolor TRIGLYCERIDES liquicolor GLUCOSE liquicolor UREA liquiuv GLUCOSE liquiuvmono URIC ACID liquicolor GOT (ASAT) IFCC mod. liquiuv URIC ACID liquicolor plus GPT (ALAT) IFCC mod. liquiuv Last updated: Page 22
9 Immunoturbidimetry anti-steptolysin-o (ASO) CYSTATIN-C liquidirect APOLIPOPROTEIN A1 (APO A1) IMMUNOGLOBULINS direct IgA APOLIPOPROTEIN B (APO B) IMMUNOGLOBULINS direct IgG COMPLEMENT C3 IMMUNOGLOBULINS direct IgM COMPLEMENT C4 MICROALBUMIN CRP-hs TRANSFERRIN Last updated: Page 23
10 Intuitive user software Optimized for touch screen Page 26
11 Reliable results and easy creation of new methods Complete reaction curve for EVERY test Page 27
12 Reliable results Statistics for every sample - not only QC Page 28
13 Sample positions Long walk-away time High number of sample positions assures long walk-away time Throughput max. [t/h] Page 29
14 Efficient workflow Ready for automation of modern laboratories Full random-access, free choice of execution order Bi-directional LIS LIS standardized according ASTM Continuous loading and STAT LIS with standard Ethernet cable Primary tubes Internal barcode reader included Page 30
15 Maximum flexibility Wide choice of sample and reagent vials Reagents 20 ml bottles 1 ml cups 50 ml bottles 5 ml tubes 7 ml tubes 3 ml tubes 1 ml cups Samples Up to 16x100mm, 10 ml 3.5 ml cups Primary tubes 5 ml tubes Page 31
16 Page 32 Unique and recognizable design
17 Page 33
18 Throughput High typical throughput HumaStar 100 has a constant throughput for 1- and 2-shot methods Maximum - Single Shot Double Shot Methods Typical Mix 200 t/h 100 t/h 64 t/h 100 t/h 95 t/h 127 t/h 0 t/h Mindray BS-120 HumaStar 100 Biosystems A15 HumaStar 200 Page 34
19 Economic and efficient operation Cuvette Wash Station tests with 80 cuvettes Low consumable cost Price per test on instruments without wash station can be more than double the price on HumaStar 100/200 Very low carry-over 8-step wash cycle 2 nd cleaning solution Extra washing definable in method Automatic monitoring of cuvettes Low water consumption 2nd cleaning solution Page 35
20 Cost per test calculation Available on HUMAN homepage: SERVICE > FAQ Page 36
21 Reduce expenses New clinical chemistry family (low to medium throughput) HumaStar 100 (March 2013) HumaStar 200 (Mai 2013) HumaStar 300SR (2017) Identical user software Identical hardware components Page 37
22 Reduce expenses Identical user software Reduced staff training Reduced end-user training Reduced support Identical hardware components Reduced spare part stock Reduced training for service engineers Faster repair Page 38
23 Modern and easy connection USB Ethernet cable Windows 7 or XP * (32- or 64-bit) No old RS-232 cable * Windows 8 compatibility in evaluation Page 39
24 No result will be lost Failure proof connection Page 41
25 Easy maintenance Monitoring of lifetime Pumps Lamp Filters Cuvettes Page 42
26 Easy maintenance Access to lamp and pumps Lamp Pumps Page 43
27 Reliable quality High quality components High production depth Made in Europe Extensive testing Page 44
28 Competitive advantages
29 Sample positions Throughput max. [t/h] Page 46
30 A15 A25 Pentra C200 BS-120 Cobas C111 C100 C100plus C200i C200iplus BS-200 Page 47
31 HumaStar 100 Feature comparison 1 Human HumaStar 100 Horiba Pentra C200 Mindray BS-120 Biosystems A15 Roche Cobas C111 Open/closed Open Closed Open Open Closed Throughput max. 100 t/h const. 90 t/h const. 100 t/h 150 t/h 60 t/h Reagent cooling Yes Yes Yes No Yes Wash station Yes No No No No Sample pos Reagent pos x2 * x2 * 1 Barcode Internal Internal External? Smp. & Rgt. Primary tubes 16x100 mm Yes Yes 15x100 mm 16x100 mm LIS ASTM Yes Yes Yes ASTM Weight 51 kg 95 kg 75 kg 45 kg 35 kg Water consumpt. < 1 l/h < 2.1 l/h 2.5 l/h 0.5 l/h < 2 l/day ISE No Optional Optional No Optional Cuvettes 80 washable 192 disposable 40 disposable 120 disposable 60 disposable *1 Nbr. of methods X Reag. per method Page 48
32 HumaStar 100 Feature comparison 2 Human HumaStar 100 Landwind C100 Vital Scientific Pro XS Human HumaStar 80 Open/closed Open Open Open Open Throughput max. 100 t/h const. 150 t/h 75 t/h 80 t/h Reagent cooling Yes Yes Optional No Wash station Yes No No No Sample pos Reagent pos Barcode Internal External External External Primary tubes 16x100 mm Yes Yes No LIS ASTM Yes LIS-2A Yes Weight 51 kg 50 kg 67 kg 42 kg Water consumpt. < 1 l/h 3.5 l/h (C100plus) 0.25 l/h ISE None Optional No No Cuvettes 80 washable 81 disposable 48 disposable 144 disp. Comments C100plus with Wash station Batch, Flow-Cell Page 49
33 HumaStar 100 Feature comparison 3 Human HumaStar 100 ISE Logotech Miura One Open/closed Open Open Throughput max. 100 t/h const. 120 t/h Reagent cooling Yes Yes Wash station Yes Yes Sample pos Reagent pos Barcode Internal Optional Primary tubes 16x100 mm 13x85 mm LIS ASTM Yes Weight 51 kg 42 kg Water consumpt. < 1 l/h < 2 l/h ISE None Optional Cuvettes 80 washable 80 washable Comments Page 50
34 HumaStar 200 Feature comparison 1 HumaStar 200 Mindray BS-200 Biosystems A25 Landwind C200i Open/closed Open Open Open Open Throughput max. 200 t/h 200 t/h 240 t/h 225 t/h Reagent cooling Yes Yes Yes Yes Wash station Yes (2 sol.) No No No Sample pos Reagent pos Barcode Internal Internal? Optional Primary tubes 16x100 mm Yes 15x100 mm Yes LIS ASTM Yes Yes HL7 Weight 51 kg 116 kg 73 kg 120 kg Water consumpt. < 2 l/h 3.5 l/h (BS-200E) 1 l/h < 1,5 l/h ISE No Optional No Optional Cuvettes 80 washable 80 disposable 120 disposable 81 disposable Comments BS-200E with wash station C200iplus with wash station Page 51
35 HumaStar 200 Feature comparison 2 HumaStar 200 Elitech Flexor EL80 Elitech Flexor EL150 Elitech Flexor EL200 Open/closed Open Open Open Open Throughput max. 200 t/h 75 t/h 133 t/h 180 t/h Reagent cooling Yes Optional Yes Yes Wash station Yes (2 sol.) No Yes Yes Sample pos Reagent pos Barcode Internal Optional external Internal Internal Primary tubes 16x100 mm 13x75 mm 13x75 mm 13x75 mm LIS ASTM LIS-2A LIS-2A LIS-2A Weight 51 kg 67 kg 75 kg 95 kg Water consumpt. < 2 l/h 250 ml/h 950 ml/h 500 ml/h ISE No Optional Optional Optional Cuvettes 80 washable 48 disposable 48 washable 48 washable Comments Integraded PC Integrated PC Page 52
36 HumaStar 200 Feature comparison 3 HumaStar 200 Roche Cobas C311 DiaSys Respons 910 DiaSys Respons 920 Open/closed Open Closed Closed Closed Throughput max. 200 t/h 300 t/h 150 t/h 200 t/h Reagent cooling Yes Yes No Yes Wash station Yes (2 sol.) Yes No Yes Sample pos Reagent pos (casseettes) 30 (x2) 30 (x2) Barcode Internal Internal Internal Internal Primary tubes 16x100 mm 16x100 mm 16x100 mm? LIS ASTM Yes (RS 232) Yes Yes Weight 51 kg 270 kg 60 kg 110 kg Water consumpt. < 2 l/h 12 l/h < 1 l/h < 7.5 l/h ISE No Yes No Yes Cuvettes 80 washable Washable 105 disposable 45 washable Comments Page 53
37 HumaStar 200 Feature comparison 4 HumaStar 200 FUJIFILM NX 500 Miura 200 Pictus 200 Open/closed Open Closed Open Open Throughput max. 200 t/h 128 t/h 240 t/h 200 t/h Reagent cooling Yes Not necessary Yes No Wash station Yes (2 sol.) Not necessary Yes (2 sol.) No Sample pos Reagent pos. 30? Barcode Internal Optional (extern) Optional (Smp&Rgt) Optional Primary tubes 16x100 mm 16x100 mm 13x100 mm 13x100 mm LIS ASTM Yes Yes ASTM Weight 51 kg 25 kg? 50 kg Water consumpt. < 2 l/h None < 2 l/h <0.5 l/h ISE No Yes Optional No Cuvettes 80 washable Not necessary 80 washable 80 disposable Comments POCT, dry chem. 1 arm Page 54
38 HumaStar 200 Feature comparison 4 HumaStar 200 Elitech Selectra Pro M Open/closed Open Open Throughput max. 200 t/h 180 t/h Reagent cooling Wash station Yes Yes (2 sol.) Sample pos. 60 Reagent pos. 30 Barcode Primary tubes LIS Weight Water consumpt. ISE Cuvettes Comments Internal 16x100 mm ASTM 51 kg < 2 l/h No 80 washable Page 55
39 HumaStar 100 A15 vs. Page 56
40 HS100 vs. Biosystems A15 Item Advantage Human Advantage Biosystems A15 Features Equivalent Methods/ Reagents Wash Station (vs. disposable cuvettes) Reagent refrigeration UPS included Sample barcode (especially interesting for LIS) Crash detection of needle Nbr. sample positions (60 vs. 48) Nbr. reagent positions (30 vs. 20) Show complete reaction curve 4 flexible racks for reagents and samples No ISE Primary tubes (16mm vs. 15mm) European origin Open instrument 100 t/h constant vs. 150 t/h max (= ~95 t/h typical) Methods validated One supplier for reagent and instrument Pre-filled in A15 reagent bottles (vs. MPR) Page 57
41 HS100 vs. Biosystems A15 Advantage HumaStar Explanation The main advantages of HumaStar 100 are the wash station and reagent refrigeration. The wash station saves money and time. Money: A15 has consumable cost for disposable cuvettes. HumaStar can run tests with only 80 cuvettes. Time: On A15 manual changing of cuvettes is necessary after a test was run. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On A15 the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money. A15 has flexible tray for reagents and samples. However the total number of samples and reagents that the user can place on the instrument is higher on HumaStar. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. Equivalent Throughput: A15 has a maximum throughput which is 150 t/h, whereas HumaStar 100 can only reach a maximum of 100 t/h. But the throughput of HumaStar 100 is constant for 1- and 2-shot methods. In a typical mix A15 will only reach 95 t/h. => The throughput is equivalent on both instruments. Biosystems and Human both offer instruments, reagents, and validated methods out of one hand. Advantage A15 Biosystems sells the reagent in bottles that can be placed directly on the instrument. Page 58
42 HumaStar 100/200 Cobas C111 vs. Page 59
43 HS100/200 vs. Roche Cobas C111 Item Advantage Human Advantage Roche Cobas C111 Features Wash Station (vs. disposable cuvettes) Big screen A4 printing Nbr. sample positions (60 vs. 8) Up to 30 reagents/methods (vs. 14) Equivalent Methods/ Reagents Throughput Open instrument 100 or 200 t/h (vs. 60 t/h) Reagent cooling Primary tubes Sample barcode reader Pre-installed and validated methods Name and reputation of Roche Small integrated PC, screen and printer ISE (optional) Barcoded reagents in pre-filled bottles 1-5 open channels (optional) Page 60
44 HS100/200 vs. Roche Cobas C111 Advantage HumaStar Equivalent Advantage Cobas Explanation The main difference is that Cobas C111 is a closed instrument. HumaStar 100/200 are open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also preinstalled and validated methods, Cobas C111 does not have an advantage in that respect. There are three other massive advantages of HumaStar: -On HumaStar the user can place up to 60 samples, whereas only 8 samples can be placed on Cobas C111. This leads to a much a higher walk-away time on HumaStar. -The HumaStar has a wash station, which is much more cost and time efficient than disposable cuvettes on Cobas C111 (for explanation also see Biosystems A15). -HumaStar 100 and 200 are much faster than Cobas C111. The throughput of Cobas is only 60 t/h and much closer to HumaStar 80 than HumaStar 100 or 200. The possibility of automation of the laboratory workflow is equivalent on both instruments. HumaStar and Cobas C111 both can use primary tubes, they both have a built in sample barcode reader, both instruments have a standardized (ASTM) LIS protocol, and both instrument support continuous loading. Roche reagents are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles is easier. The reputation of Roche is very good. Page 61
45 HumaStar 200 Cobas C311 vs. Page 62
46 HS200 vs. Roche Cobas C311 Item Advantage Human Advantage Roche Cobas C311 Features Price of instrument and reagents Low water consumption (<2 vs. 12 l/h) Low energy consumption (<200 vs VA) Small footprint (width 69 vs. 134cm) Low weight (51 vs. 270 kg) LIS via RJ-45 (vs. RS-323) No fixed water connection needed Equivalent Methods/ Reagents Throughput Open instrument (50 methods programmable: Human or open channels) Reagent cooling Primary tubes Sample barcode reader Cuvette wash station Pre-installed and validated methods Name and reputation of Roche ISE (optional) Loading STAT and reagents without opening instrument Clot detection More sample positions (110 vs. 60) Barcoded reagents in pre-filled bottles Master-Curve calibration on reagents 42 reagent cassette positions (vs. 30 bottles on HumaStar) 300 t/h (vs. 200 t/h) photometric 180 t/h ISE Page 63
47 HS200 vs. Roche Cobas C311 Advantage HumaStar Equivalent Advantage Cobas Explanation The main difference is that Cobas C311 is a closed instrument. HumaStar 100/200 are open instruments. No limitations regarding reagents and methods he wants to use. There are three main advantages of HumaStar: -Price of the instrument itself is much lower than C311. -Price of multi-purpose reagents on HumaStar 100/200 is lower than reagents for C311. -No need of a fixed water connection (deionized water)*. -Lower consumption of water. -Lower consumption of energy and takes up less room in the laboratory. Both instruments offers pre-installed and validated methods, which assure reliable results. Roche reagents are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles and loading of STAT is easier. Throughput of C311 is higher and it can load more reagents (parameters) at the same time. The reputation of Roche is very good. Cobas C311 can benefit most of its advantages an a high throughput laboratory. * Roche also uses water to reconstitute the reagent (high quality necessary) Page 64
48 HumaStar 100 Pentra C200 vs. Page 65
49 HS100 vs. Horiba Pentra C200 Item Advantage Human Advantage Pentra C200 Features Wash Station (vs. disposable cuvettes*) Nbr. reagent positions (30 vs. 15x2* 1 ) Nbr. sample positions (60 vs. 15) Less weight (51 vs. 95 kg) Equivalent Methods/ Reagents Open instrument ISE (optional) Integrated computer and screen Cooled sample tray Fixed cycle (const. throughput) 100 vs. 90 t/h Reagent cooling Intuitive touch screen user software Sample barcode included Shock detection of needle Primary tubes Pre-installed and validated methods Barcoded reagents in pre-filled bottles Pentra C200 has192 cuvettes in stock *1 Reagent cassete with R1 and R2 Page 66
50 HS100 vs. Horiba Pentra C200 Advantage HumaStar Equivalent Advantage Pentra Explanation The main difference is that Pentra is a closed instrument. HumaStar 100/200 are open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also preinstalled and validated methods, Pentra does not have an advantage in that respect. There are two other advantages of HumaStar: -On HumaStar the user can place up to 60 samples, whereas only 15 samples can be placed on Pentra. This leads to a much a higher walk-away time on HumaStar. -The HumaStar has a wash station, which is much more cost and time efficient than disposable cuvettes on Pentra (for explanation also see Biosystems A15). HumaStar 100 and Pentra both have a constant throughput which is approximately equivalent. Reagent cooling, primary tubes, sample barcode reader, and a shock detector are also present on both instruments. Horiba offers reagents that are ready to use in prefilled and barcode labeled bottles. Handling of reagent bottles is easier. PC and monitor are integrated and do not need to be purchased separately. Page 67
51 HS100 vs. Horiba Pentra C200 Customer claims Pentra has an separate mixing unit. It should be faster. Because Pentra has disposable cuvettes, there is no carry over in the cuvettes. HumaStar 100/200 have washable cuvettes, which will lead to carry over. Possible reply! Pentra and HS100 both work with a fixed cycle. Thus having a fixed throughput for 1- and 2- shot reagents. HumaStar 100 has a 36 sec. cycle: 1 hour/36 sec. = 100 t/h Pentra C 200 has a 40 sec. cycle: 1 hour/40 sec. = 90 t/h => HS100 is even slightly faster than Pentra C200 The washing procedure of HumaStar 100/200 is so sophisticated that carry over is comparable to disposable cuvettes. There are several measures to assure this: 8- step washing of every single cuvette Normal Systemic and a Special Wash solution are connected to the instrument (most other instrument only have one type of wash solution). A third wash solution Cuvette Clean can be programmed in the methods settings if necessary (e.g. turbidimetry). The intensity of the washing can be increased from 1 (normal) to 4 (extended) in the method settings if necessary. The needle is washed internally and externally. Incompatibilities can be defined in the method settings. This will prevent the consecutive execution of parameters that could influence each other in one cuvette. => In practice carry over is comparable on HumaStar and Pentra. HumaStar has the advantage of lower consumable cost (cuvettes). Page 68
52 HumaStar 100 BS-120 vs. Page 69
53 HS100 vs. Mindray BS-120 Item Advantage Human Advantage Mindray Features Equivalent Methods/ Reagents Service Comments Wash Station 60 sample positions (vs. 8) Throughput 100 t/h const. (vs. 100 t/h max) Internal sample barcode reader Made in Europe Intuitive touch screen user software Pre-installed and validated method Reagents and instruments from one source Technical service available in most countries Human offers local trainings Optional ISE Reagent cooling Nbr. reagent positions (30 vs. 28) Page 70
54 HS200 vs. Mindray BS-120 Advantage HumaStar Explanation There are 5 massive advantages of HumaStar The wash station saves money and time. Money: BS-120 has consumable cost for disposable cuvettes. HumaStar can run tests with only 80 cuvettes. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. -HumaStar 100 is much faster than BS-120. The max. throughput of BS-120 is 100 t/h, but the typical throughput will only be at approx. 60 t/h, because it is not constant for 1- and 2-shot methods. -On HumaStar the user can place up to 60 samples, whereas only 8 samples can be placed on BS This leads to a much a higher walk-away time on HumaStar. -HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. Users can be sure about the results. On BS- 120 lots of time needs to be spend to reach a precision and performance of parameters as we have on HumaStar 100. Sometimes it will be impossible to reach the performance of HumaStar, because Human has the possibility to adapt the hardware and the software of the instrument to match the reagents. The user in the laboratory does not have this possibility. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. The modern user software of HumaStar is easier to use and offers more features than Mindray. Page 71
55 HS200 vs. Mindray BS-120 Equivalent Advantage BS-120 Explanation Reagent cooling. Number of reagent position is approximately equivalent. Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient. Page 72
56 HumaStar 100 Miura One vs. Page 73
57 HS100 vs. Miura One Item Advantage Human Advantage Miura One Features 60 sample positions (vs. 15) 30 reagent positions (vs. 19) Throughput 100 t/h constant (vs. 150 t/h max., 76 typical) Intuitive touch screen user software UPS included Primary tubes 16x100mm (vs. 13x85mm) Equivalent Methods/ Reagents Service Comments Wash Station Reagent cooling Made in Europe Open instrument Needle crash detection Internal sample barcode included Optional ISE Optional internal reagent barcode reader Barcoded reagents Page 74
58 HumaStar 200 Kroma vs. Page 75
59 HS200 vs. Linear Kroma Item Advantage Human Advantage Miura One Features 60 sample positions (vs. 15) 30 reagent positions (vs. 20) Throughput 200 t/h (vs. 150) Intuitive touch screen user software UPS included Primary tubes 16x100mm (vs. 13x100mm) Equivalent Methods/ Reagents Service Comments Optional ISE Internal reagent barcode reader Wash Station Reagent cooling Made in Europe Open instrument Needle crash detection Internal sample barcode included Barcoded reagents Page 76
60 HumaStar 200 respons 910 vs. Page 77
61 HS200 vs. DiaSys respons 910 Item Advantage Human Advantage respons 910 Features Equivalent Methods/ Reagents Throughput Wash Station (vs. disposable cuvettes) UPS included (end user value 720) Reagent refrigeration Open instrument Nbr. sample positions (60 vs. 30) Slightly higher (200 vs. 150 t/h) No ISE module Barcoded primary tubes (16x100mm) European origin Methods validated One supplier for reagent and instrument Nbr. reagent positions (30 vs. 30x2) STAT can be loaded without opening the cover Pre-filled in respons reagent bottles (vs. MPR) Internal reagent barcode reader Page 78
62 HS200 vs. DiaSys respons 910 Advantage HumaStar Explanation The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: respons 910 has consumable cost for disposable cuvettes. HumaStar can run tests with only 80 cuvettes. Depending on your price per disposable cuvette of respons 910, the price per test can be twice as high as on HumaStar 200. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. UPS is included in the standard offer of HumaStar at no extra cost. HumaStar 200 is an open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Because Human has also preinstalled and validated methods, respons does not have an advantage in that respect. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On respons the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money. Throughput of HumaStar 200 is 50 t/h higher than respons 910. This is difference can make a difference in laboratories with a higher number of samples per day. User can also place 60 samples on HumaStar at the same time. On respons 910 user can only place half of that (30 samples), making HumaStar 200 faster and more suitable if the laboratory has a higher number of samples per day. Page 79
63 HS200 vs. DiaSys respons 910 Equivalent Advantage respons 910 Explanation DiaSys and Human both offer instruments, reagents, and validated methods out of one hand. DiaSys sells the reagent in bottles that can be placed directly on the instrument and are recognized by an internal barcode reader. On respons 910 user can place up to 30 different parameters, each of them can use up to two reagents. On HumaStar the user can place 30 different bottles. If a parameter uses two reagents it will occupy two positions, thus limiting the number of parameters loaded on the instrument. STAT samples can be loaded on respons 910 without opening the cover. On HumaStar 200 the user needs to press pause and wait for approx. 20 seconds before he can open the cover and place the STAT sample. Page 80
64 HumaStar 200 respons 920 vs. Page 81
65 HS200 vs. DiaSys respons 920 Item Advantage Human Advantage respons 920 Features Water consumption (2 vs. 7.5 l/h) UPS included (end user value 720) Open instrument Nbr. sample positions (60 vs. 30) Weight (51 vs. 110 kg) Nbr. reagent positions (30 vs. 30x2) Optional ISE module Constant throughput of 200 t/h Equivalent Methods/ Reagents Cuvette wash station Reagent refrigeration European origin Methods validated One supplier for reagent and instrument Pre-filled in respons reagent bottles (vs. MPR) Internal reagent barcode reader Page 82
66 HS200 vs. DiaSys respons 920 Advantage HumaStar Explanation HumaStar 200 is an open instruments. The user of HumaStar is not limited in the reagents and methods he wants to use on the instrument. Users might be limited using respons 920, if they want to measure parameters that are not available from Diasys or reagents cannot be supplied on time. Because Human has also pre-installed and validated methods for its Multi Purpose Reagents, respons does not have an advantage in that respect. User can place 60 samples on HumaStar at the same time. On respons 920 user can only place half of that (30 samples), making HumaStar 200 more suitable if the laboratory has a high number of samples per day. HumaStar 200 is slightly smaller and its weight is only half the weight of respons 920. The water consumption of HumaStar 200 is much lower (< 2 l/h) than the water consumption of respons 920 (< 7.5 l/h) Page 83
67 HS200 vs. DiaSys respons 920 Equivalent Advantage respons 920 Explanation HumaStar 200 and respons 920 are very similar instruments. Human and DiaSys both supply instrument and validated reagents out of one hand. Thus the user can be sure, to get reliable results. Both instruments have a cuvette wash station and reagent cooling. Both instruments are of European origin, thus having a good reputation in the market. DiaSys sells the reagent in bottles that can be placed directly on the instrument and are recognized by an internal barcode reader. On respons 910 user can place up to 30 different parameters, each of them can use up to two reagents. On HumaStar the user can place 30 different bottles. If a parameter uses two reagents it will occupy two positions, thus limiting the number of parameters loaded on the instrument. Respons 920 has an optional ISE module for Na, K, Cl, Li. Page 84
68 HumaStar 200 A25 vs. Page 85
69 HS200 vs. Biosystems A25 Item Advantage Human Advantage Biosystems A25 Features Wash Station (vs. disposable cuvettes) UPS included (end user value 720) Sample barcode included (value > 500) (especially interesting for LIS) Shock detection of needle Show complete reaction curve Intuitive touch screen user software 3 independent sample racks Equivalent Nbr. sample positions (60 vs. 72), nbr. reagent positions (30 vs. 30) No ISE Primary tubes (16mm vs. 15mm) European origin Reagent refrigeration Open instrument Methods/ Reagents Throughput Methods validated One supplier for reagent and instrument Pre-filled in A25 reagent bottles (vs. MPR) Slightly higher (200 vs. 240 t/h) Page 86
70 HS200 vs. Biosystems A25 Advantage HumaStar Equivalent Advantage A25 Explanation The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: A25 has consumable cost for disposable cuvettes. HumaStar can run tests with only 80 cuvettes. Time: manual changing of cuvettes is necessary after a test has been run in a cuvette. UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. The modern user software of HumaStar is easier to use and more intuitive (see screen shots on next slide). Biosystems and Human both offer instruments, reagents, and validated methods out of one hand. Number of samples and reagents are approximately equivalent. On HumaStar you can place primary tubes up to 16 mm, on A25 you can place primary tubes up to 15 mm. Biosystems sells the reagent in bottles that can be placed directly on the instrument. Throughput of A25 is 20% higher than HumaStar 200. However, in routine use this difference will not be noticed by the user. Page 87
71 Page 88 HS200 vs. Biosystems A25
72 HumaStar 200 BS-200 vs. Page 89
73 HS200 vs. Mindray BS-200 Item Advantage Human Advantage Mindray Features Equivalent Service Methods/ Reagents Comments Cuvette Wash Station 60 sample positions (vs. 40) UPS included Made in Europe Easy to use software Less weight (51 vs. 116 kg) Less water consumption (< 2 l/h vs. 3.5 l/h) Optional ISE 40 reagent positions (vs. 30) Throughput 200 t/h (even though Mindray has extra mixer) Reagent cooling Technical service available in most countries Human offers local trainings Methods validated One supplier for reagent and instrument BS-200E with Wash Station Page 90
74 HS200 vs. Mindray BS-200 Advantage HumaStar Equivalent Advantage BS-200 Explanation -If competing against BS-200 (not BS-200E): The wash station saves money and time. (see also A15 for explanation). If competing against BS-200E: The water consumption on HumaStar is lower. -On HumaStar the user can place up to 60 samples, whereas only 40 samples can be placed on BS HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. (see also BS-120 for explanation) -UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. -The modern user software of HumaStar is easier to use and offers more features than Mindray. -The weight of HumaStar is only half the weight of BS-200. Throughput: The throughput on both instruments is approximately the same. Reagent cooling. Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient. Number of reagent position is slightly higher. However multiple reagent trays can be handled (saved) by HumaStar. Page 91
75 HumaStar 200 LW C200i vs. Page 92
76 HS200 vs. Landwind C200i Item Advantage Human Advantage Landwind C200i Features Equivalent Service Methods/ Reagents Comments Cuvette wash station Barcode scanner included UPS included Easy to use software Made in Europe Less weight (51 vs. 116 kg) Human can offer technical service in most countries Human offers local trainings Pre-installed and validated method Reagents and instruments from one source Reagent cooling 60 sample positions Optional ISE 60 reagent positions (vs. 30) Slightly higher throughput (225 vs. 200 t/h) C200iplus with wash station (6 l/h) Page 93
77 HS200 vs. Landwind C200i Advantage HumaStar Equivalent Advantage BS-200 Explanation -If competing against C200i (not C200iplus): The wash station saves money and time. (see also A15 for explanation). If competing against C200iplus: The water consumption on HumaStar is lower. -HumaStar is made in Europe. -HumaStar has pre-installed and validated methods. (see also BS-120 for explanation) -UPS and barcode scanner are included in the standard offer of HumaStar at no extra cost. -The modern user software of HumaStar is easier to use and offers more features than Landwind. Landwind software is very difficult to use. -The weight of HumaStar is only half the weight of C200i. Reagent cooling. Number of sample positions. The throughput is slightly higher on C200i. Optional ISE. However HumaStar can measure all electrolytes using chemical reagents. ISE modules often require high maintenance if the number of samples that are measured per day is not sufficient. Number of reagent position is higher. However multiple reagent trays can be handled (saved) by HumaStar. Page 94
78 HumaStar 200 NX 500 vs. Page 95
79 HS200 vs. FUJIFILM NX 500 Item Advantage Human Advantage NX 500 Features Equivalent Service Methods/ Reagents Open instrument A4 printout 60 sample positions (vs. 1) Lower price per test More than 40 Human parameters preinstalled Can be used with other reagents that are available on the market No calibration necessary No water consumption Compact and light weight Optional plasma filter (whole blood) parameters FUJIFILM dri-chem reagent slides ONLY Comments Suited for central or hospital laboratories Dry chemistry POCT suited for physician's offices Page 96
80 HS200 vs. FUJIFILM NX 500 Advantage HumaStar Equivalent Advantage NX 500 Explanation -The HumaStar is an instrument suited for a central or hospital laboratory. It can load and run up to 60 samples at once. NX 500 can only run one sample at a time. NX 500 is a designated POCT instrument for physician s offices or similar operation areas which run only very few samples. HumaStar also has an internal sample barcode reader, NX 500 only has an optional handheld scanner. -Price per test is much lower on HumaStar than on NX 500. NX 500 is optimized for easy operation, not for low cost or higher throughput. On NX 500 disposable consumables are used for plasma separation and pipetting (-> waste and cost). -HumaStar comes with more pre-installed parameters than NX 500. Some parameters, such as HbA1c are not available on NX 500. HumaStar is also an open system, you can use most clinical chemistry reagents that are available on the market. On NX500 you can only run the dry reagent slides which are provided by Fujifilm. -Easy operation: No on-site calibration necessary, no centrifugation of sample necessary. -Small footprint and low weight: Integrated computer and thermal printer. Page 97
81 HumaStar 200 Pictus 200 vs. Page 98
82 HS200 vs. Pictus 200 Item Advantage Human Advantage Pictus Features Equivalent Methods/ Reagents Throughput Wash Station (vs. disposable cuvettes) UPS included (end user value 720) Reagent refrigeration Primary tubes up to 16x100 mm (optional) Sample barcode included (value > 500) (especially interesting for LIS) No ISE module European origin Nbr. reagent positions (30 vs. 48) Methods validated One supplier for reagent and instrument Up to 200 t/h Pre-filled reagent bottles (vs. MPR) Page 99
83 HS200 vs. Diatron Pictus 200 Advantage HumaStar Equivalent Advantage Pictus 200 Explanation The main advantages of HumaStar 200 is the wash station. The wash station saves money and time. Money: Pictus 200 has consumable cost for disposable cuvettes. HumaStar can run tests with only 80 cuvettes. Depending on your price per disposable cuvette of Pictus 200, the price per test can be twice as high as on HumaStar 200. Time: manual changing of cuvettes is necessary on Pictus 200 after a test has been run in a cuvette. UPS is included in the standard offer of HumaStar at no extra cost. Reagent refrigeration leads to reliable results, longer on-board and calibration stability. On Pictus 200 the user either has to place the reagent in the refrigerator after every run, but he will loose time doing this. If he leaves the reagent on the instrument he will waste reagent when it gets warm and he has to throw it away - he is loosing money. The throughput of both instruments is identical. Both instruments are of European origin. Both instruments offer validated applications for their reagents. -Users can load more reagents on board. (However these reagents must not stay on Pictus 200 for a long time, because it is not cooling the reagents.) Page 100
84 HumaStar 200 Miura 200 (one arm) vs. Page 101
85 HS200 vs. Miura 200 Item Advantage Human Advantage Miura 200 Features Nbr. of sample positions (60 vs. 49) More compact, less width on the desk (69 vs. 93cm) Extractable reagent and samples trays 4 types of reagent bottles (vs. 2) 2 types of sample trays (4 types of tubes and cups) Primary tubes up to 16x100 mm (optional) Vitro-ceramic internally + externally coated probe (vs. no coating) Internal + external needle wash Continuous run, never stop, with rapid execution of urgent tests Repetition of the calibration with recalculation of the results with the new valid calibration Multiple dyamic worklists (WL sheets) LIS operating on dedicated WL sheets Autodilution of the calibration including concentration of the sample (dilution rate < 1) Electronics easy accessible and separated from the hydraulics Water consumption (mono-reagent 200 t/h) 1.5 l/h (vs. 3-4 l/h) UPS included (end user value 720) Sample barcode included (value> 500; especially interesting for LIS) Optional ISE module Nbr. reagent positions (30 vs. 30/43) Host query LIS Optional internal reagent barcode reader Page 102
86 HS200 vs. Miura 200 Item Advantage Human Advantage Miura 200 Equivalent Methods/ Reagents Throughput Reagent cooling Made in Europe Open instrument Needle crash detection Cuvette wash station Bi-directional LIS Methods validated One supplier for reagent and instrument Pre-filled reagent bottles (vs. MPR) Up to 200 t/h (photometric) Page 103
87 HS200 vs. Logotech ISE Miura 200 Advantage HumaStar Explanation UPS is included in the standard offer of HumaStar at no extra cost. Sample barcode reader is included in the standard offer of HumaStar at no extra cost. HumaStar 200 is more flexible in the type of reagent bottles you can use. You can use up to 4 different reagent containers (low dead volume = less reagent is wasted). HumaStar 200 is more flexible in the type of sample tubes/cups you can use. On HumaStar 200 you have the choice between two different and extractable sample trays. You can also use 4 different sample tubes or cups and tubes up to 16mm diameter. On HumaStar 200 you have internal AND external needle wash, minimizing shifted results due to needle carry-over. HumaStar consumes less water than the Miura 200. Imagine you have calibrated your instrument and you have finished running your patient tests. Then you find out that the calibration was not valid. On most instruments (including Miura 200) you would have to run all tests again. On HumaStar 200 you can just repeat the calibration and the recalculate all patient tests using the valid calibration. Thus your are saving a lot of reagent and time. On HumaStar 200 electronic and hydraulic components are strictly separated. If there is a leakage in the hydraulics, the electronic components are protected from being destroyed by the water. Page 104
88 HS200 vs. Logotech ISE Miura 200 Equivalent Advantage Miura 200 Explanation HumaStar 200 and Miura 200 are two very similar instruments. Some components are even shared by both instruments. Both instruments are of European origin. Both instruments offer validated applications for their reagents. Both instruments have a cuvette wash station and reagent refrigeration. Photometric (without ISE) test throughput is 200 tests per hour on both instruments. Users can load more reagents on board. (However on HumaStar 200 it is possible to work with multiple extractable reagent trays.) There is an optional ISE module for Na, K, Cl, Li available. (However Na, K, Cl are available for HS200 as liquid reagents.) There are an optional internal reagent barcode reader and barcoded reagents available. Higher test throughput if ISE is included. Page 105
89 Product features
90 HumaStar 100 & 200 Product features 1. Design 2. Technology Main Features Hardware and Software Service and Maintenance Page 109
91 HumaStar 100 & 200 Our Pioneers for a new Line of Instruments Page 110
92 HumaStar 100 & 200 Product features 1. Design 2. Technology Main Features Hardware and Software Service and Maintenance Page 111
93 HumaStar 100 & 200 Maximum - Single Shot Throughput 80 t/h 100 t/h 180 t/h 200 t/h 200 t/h Throughput Maximum 100 t/h 0 t/h HumaStar 80 HumaStar 100 HumaStar 180 HumaStar 200 Page 112
94 100 t/h HumaStar 100 & 200 Throughput Maximum - Single Shot Double Shot Reagents Throughput Double Shot 100 t/h 200 t/h 100 t/h 0 t/h HumaStar 80 HumaStar 100 HumaStar 180 HumaStar 200 Page 113
95 Throughput Typical HumaStar 100 & 200 Throughput 200 t/h Maximum - Single Shot Double Shot Reagents Typical Mix 100 t/h 100 t/h 115 t/h 127 t/h 0 t/h 40 t/h HumaStar 80 HumaStar 100 HumaStar 180 HumaStar 200 * independent of single- or double shot methods Page 114
96 HumaStar 100 & 200 Features Open random-access Multi-step wash station Primary tubes (16x100 mm) Sample cups Reagent cooling 30 reagent and 60 sample positions Internal sample barcode reader Needle shock detector Bi-directional LIS (ASTM) Continuous loading Page 115
97 HumaStar 100 & 200 Product features 1. Design 2. Technology Main Features Hardware and Software Service and Maintenance Page 116
98 HumaStar 100 & 200 Wash Station 8-step wash cycle 2 nd cleaning solution Level sensors for all containers Difference HumaStar 100 vs vs. 8 cleaning needles Water consumption only 8 ml per test Page 117
99 HumaStar 100 & 200 Samples Removable sample tray Primary tubes and cups 60 positions up to 12.5x100 mm Optional tray: positions up to 16x100 mm Internal barcode reader included Page 118
100 HumaStar 100 & 200 Reagents HUMAN methods pre-installed and validated Substrates, enzymes, turbidimetry, electrolytes Open analyzer Removable reagent tray Reagent cooling 30 positions (one used for diluent) 4 different reagent vials Page 119
101 HumaStar 100 & 200 Product features 1. Design 2. Technology Main Features Hardware and Software Service and Maintenance Page 121
102 HumaStar 100 & 200 User Interface and Features Page 122
103 HumaStar 100 & 200 User Interface and Features Easy to use Touch screen Page 123
104 HumaStar 100 & 200 User Interface and Features Easy to use Touch screen 5 main tabs One software - Complete analyzer line Page 124
105 HumaStar 100 & 200 Extensive Information Reaction charts Page 125
106 HumaStar 100 & 200 Extensive Information Reaction charts Quality control charts Page 126
107 HumaStar 100 & 200 Extensive Information Reaction charts Quality control charts Method statistics Page 127
108 HumaStar 100 & 200 Ext. Computer and LIS LIS HumaStar PC via USB ASTM standard Bi-Directional Page 128
109 HumaStar 100 & 200 Product features 1. Design 2. Technology Main Features Hardware and Software Usability and Safety Service and Maintenance Page 129
110 HumaStar 100 & 200 Minimum Maintenance Monitoring of life time Pumps Page 130
111 HumaStar 100 & 200 Minimum Maintenance Monitoring of life time Pumps Filters Lamp Page 131
112 HumaStar 100 & 200 Minimum Maintenance Monitoring of life time Pumps Filters Lamp Cuvettes Page 132
113 HumaStar 100 & 200 Minimum Service Quality High quality components High production depth Made in Europe Extensive testing Easy access Page 133
114 HumaStar 100 & 200 Minimum Service Quality Easy access Lamp Page 134
115 HumaStar 100 & 200 Minimum Service Quality Easy access Lamp Peristaltic pumps Page 135
116 HumaStar 100 & 200 Minimum Service Quality Easy access Lamp Peristaltic pumps Remove top cover Page 136
117 HumaStar 100 & 200 Minimum Service Quality Easy access Lamp Peristaltic pumps Remove top cover Remove complete cover Page 137
118 52 cm HumaStar 100 & 200 Size and Weight 169 cm 76 cm 69 cm 51 kg Page 138
119 The end
120 Page 141 Get in the race and ask for more information about HumaStar 100 and 200.
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