Dr. VENKATA RAMANA DODDI
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1 Dr. VENKATA RAMANA DODDI Personal Data: Parents: Adibabu (late) & Sanyasamma Date of Birth: Sex: Nationality: Male Indian Address for Correspondence:, Assistant Professor, Department of Chemistry and Chemical Sciences, Central University of Jammu, Jammu Affiliations:
2 Research grants as PI: 1. DST- INSPIRE [IFA12-CH-36] : 35 Lakhs ( 5 years) Project title: "Synthesis and biological evaluation of Nordihydroguaiaretic acid (NDGA) and its analogues". 2. DST-SERB : 37 Lakhs (3 Years) Project title: Understanding the novel reactivity and better utilization of bicyclic amidines. 3. Central University of jammu : 2 Lakhs (2 Years) Project title: Novel synthesis of terminal alkynes and their derivatives. Teaching experience: 1. Teaching assistant : IIT Kanpur for undergraduate lab course (2006) 2. Assistant professor (AcSIR) : at Indian Institute of Chemical Technology, Hyderabad. Current research activities (2012 to Present): Synthesis of new chemical biologically active compounds: Nordihydroguaretic acid and its analogues. We have actively involved in the successful synthesis of Lamellarins J and K and produced 500mg of final compound. Developed an attractive alternative method for the synthesis of terminal alkynes. (Published in Organic Letters Journal and this appeared as most read articles of organic letters of that month)
3 Controlled Reactivity of 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) in the Selective Synthesis of 1-(Bromoethynyl)arenes (Published in Wiley- Advanced Synthesis and Catalysis). Developed an metal free synthesis of 1,3-diynes and this work currently is under progress. Reagent economic synthesis of internal alkynes from insitu prepared internal alkynes.
4 Educational qualifications: B. Sc. Andhra University, Visakhapatnam, India M. Sc. Chemistry. Andhra University Campus, Visakhapatnam, India Ph. D. Chemistry. Indian Institute of Technology (IITK), Kanpur, India Post Doctoral fellow. CCNY, City University of New York, New York, USA. Publications as Independent Faculty*: 1. G. V. M. Sharma, Venkata Ramana Doddi. Macrolactones in Natural Lactones and Lactams Synthesis, Occurrence and Biological Activity. 'Wiley' New York (2013) 2. G. V. M. Sharma, P. R. Krishna, Venkata Ramana Doddi, S. Kashyap, P. S. Reddy. Application oriented catalytic organic synthesis in Industrial Catalysis and Separations: Innovations for Process Intensification. Apple Academic Press (2014). 3. A. K. Morri, Y. Thummala, Venkata Ramana Doddi*. The Dual Role of 1,8- Diazabicyclo[5.4.0]undec-7-ene (DBU) in the Synthesis of Terminal Aryl- and Styryl- Acetylenes via Umpolung Reactivity. Org. Lett., 2015, 17, [Impact factor: 6.579] 4. S. K. Moodapally, G. V. M. Sharma, Venkata Ramana Doddi*. Controlled Reactivity of 1,8- Diazabicyclo[5.4.0]undec-7-ene (DBU) in the Selective Synthesis of 1-(Bromoethynyl)arenes. Adv. Synth. Catal. 2016, 359, 1535.[Impact factor: 5.646]. Ph.D and Post Doctoral research publications: 5. Venkata Ramana Doddi, Y. D. Vankar. Synthesis of Pyrrolidine-Based Imino Sugars as Glycosidase Inhibitors. Eur. J. Org. Chem. 2007, 33, (Full Paper). [Impact factor: 3.065] 6. Amitkumar, Venkata Ramana Doddi, Y. D. Vankar. Mild and efficient method for the selective deprotection of anomeric acetal using triphenylcarbenium tetrafluroborate. J. Org. Chem. 2008, 73, [Impact factor: 4.721] 7. Venkata Ramana Doddi, Amit kumar, Y. D. Vankar. Stereoselective synthesis of mucoquercitol, (+)-gala-quercitol and 5-Amino-5-deoxy-D-vibo-quercitol from D-mannitol. Tetrahedron 2008, 64, [Impact factor: 2.641] 8. Venkata Ramana Doddi, H. P. Kokatla, A. P. J. Pal, Y. D. Vankar, Synthesis of hybrids of D- glucose and D-galactose with pyrrolidine based iminosugars as glycosidase inhibitors. Eur. J. Org. Chem. 2008, (Full Paper). [Impact factor: 3.065] 9. Venkata Ramana Doddi, P. K. Kancharla, Y. D. Vankar. Synthesis of fused pyrancarbahexopyranoses as glycosidase inhibitors. Carbohydr. Res. 2009, 344, 606. [Impact factor: 1.929] 10. K. H. Prasad, R. Lahari, P. K. Kancharla, Venkata Ramana Doddi, Y. D. Vankar Synthesis of ( )- Deoxoprosophylline, (+)-2-epi-Deoxoprosopinine, and (2R,3R)- and (2R,3S)- 3Hydroxypipecolic Acids from D-Glycals. J. Org. Chem. 2010, 75, [Impact factor: 4.721] 11. Pavan K. Kancharla, Venkata Ramana Doddi, Hari prasad kokatla, Y. D. Vankar. A concise route to ( )-shikimic acid and ( )-5-epi-shikimic acid, and their enantiomers via Barbier
5 reaction and ring-closing metathesis. Tetrahedron Lett. 2009, 50, [Impact factor: 2.379] 12. Y. S. Reddy, Venkata Ramana Doddi, Y. D. Vankar. Intramolecular ketonitrone-olefin cycloaddition reaction: Direct and stereocontrolled synthesis of nitrogenated quaternary centered aminocyclopentitols as galactosidase inhibitors. Tetrahedron Lett. 2009, 50, [Impact factor: 2.379] 13. A. P. J. Pal, P. Kadigachalam, A. Mallick, Venkata Ramana Doddi, Y. D. Vankar. Synthesis of sugar derived spiroaminols via lactonization and metathesis reactions. Org. Biomol. Chem., 2011, 9, [Impact factor: 3.562] 14. H. P. Kokatla, P. F. Thomson, S. Bae, Venkata Ramana Doddi, M. K. Lakshman, Reduction of Amine N-Oxides by diboran reagents. J. Org. Chem., 2011, 76, [Impact factor: 4.721] 15. R. Basak, S. Dharuman, Y. S. Reddy, Venkata Ramana Doddi, and Y. D. Vankar. Chem. Lett. 2012, 41, 325. [Impact factor: 1.23] 16. T. V. S. K. Vittal, S. Sudhakar, K. S. Reddy, Venkata Ramana Doddi, Ch. Lakshminarayana, M. Sridhar. Process for preparing Norbornane derivative. Patent No at IPO: No.F25/00078/2011/CHE/ Invited talks / Symposiums / Conferences / Seminars: 1. Invited International conference on Frontiers at Chemistry-Allied Sciences Interface (FCASI-2017), University of Rajasthan, Jaipur during July Invited 12 th JK Science Congress, University of Jammu, Jammu during 2-4 March Invited 11 th National Conference of Indian thermodynamics society, University of Jammu, Jammu during December Member organizing National Conference on Materials for Sustainable Development and new Technology, Central University of Jammu, Jammu during April Member organizing National Science Day 2017, Central University of Jammu, Jammu on 28 th February Member organizing University business Incubation Centre, Central university of Jammu, Jammu during April Transacting Students Engagement For Rural Community Development, Central University of Jammu, Jammu during April Challenges in Catalysis Science and Technology (CCST-2016), CSIR-Indian Institute of Chemical Technology, Hyderabad during June Advances in Cancer Therapeutics (ACT-2016), CSIR-Indian Institute of Chemical Technology, Hyderabad during 4-5 April International symposium on Nature Inspired initiatives in Chemical Trends (NIICT-2014), CSIR-Indian Institute of Chemical Technology, Hyderabad during March th International carbohydrate symposium, Indian Institute of Science, Bangalore during January Second NOST Symposium, International College for girls, Jaipur during October, Sixth National Symposium in Chemistry, IIT Kanpur during February, 2004.
6 Awards received: Awarded the INSPIRE Faculty Award-2012 by DST-INSPIRE, India. Ref No: (IFA12-CH-36) Promoted as Senior Research Fellowship (CSIR-NET) by Council for Scientific and Industrial Research in Awarded the Junior Research Fellowship (CSIR-NET-JRF) by Council for Scientific and Industrial Research (CSIR) in Andhra Pradesh State Government merit Scholarship Professional Training and Research Experience: Indian institute of Technology Kanpur, India. ( ). (Ph. D. under the supervision of Prof. Y. D. Vankar). I have done Ph. D. in organic chemistry having thesis title: Synthesis of novel polyhydroxylated pyrrolidines, cyclohexanes and their sugar hybrids as glycosidase inhibitors. Post doctoral experience: City University of New York, New York, USA. ( ) We have developed a mild and efficient method for the reduction of N-Oxides using transition metal catalysts. This method gave excellent yields comparatively those known methods in the literature. We have developed an efficient, highly diastereoselective synthesis of protected 10Samino-7S,8R,9S-trihydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene, a key component for preparing nucleoside adducts of the carcinogen BaP DE-2 corresponding to a cis ringopening of the oxirane in the metabolite. Pharmaceutical Industrial experience: ( ): SAI Advantium Pharma limited: Hydeabad ( ). Position: Research Scientist Job responsibilities are mainly synthesis of biologically active molecules. Lurasidone. (Process was filed for patent) Testimony: I hereby declare that the information given above is true to the best of my knowledge and belief. Sincerely Yours, ()
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