Dr. Heekyung BAE WED.
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1 Dr. Heekyung BAE WED.
2 1. Background 2. Objectives and Contents 3. Consortium 4. Progress with Overseas Institutions
3 1. Background : Needs of Domestic Nano-companies Recently, in the "Nanotechnology Industrialization Strategy (2015)" report, - Nano companies (570 companies surveyed, '14) believe that they are hoping to support technological innovation infrastructure for the development of new products and sharing for risk on Investment gap with the government(* Investment gap: the government is at the basic stage, and the private sector focuses on commercialization investment, and there is investment gap between TRL4 ~ 7), - In particular, obstacles to commercialization include: 1 technical difficulties (long time span, high process costs, etc.), 2 difficulty in verifying safety performance, and 3 lack of information (lack of exchange between technology and capital). 투자공백구간의위험부담분담 4 대인프라기능정비및확충 Source : Nanotechnology Industrial Strategy (MIST/MoTIE/MoE, ) For Better Chemically Yours Chemical Management Expert Group 3
4 1. Background : Extending EU REACH Regulation Obstacles to overcome for the expansion of the nano-industry market: EU-REACH REACH : Registration, Evaluation, Authorization and restriction of Chemicals It is a chemical substance management regulation that permits the registration evaluation approval and restriction according to the manufacturing imports and risks for all substances manufactured and imported in the EU within 1 ton per year since June Consulting needs for nano materials and product registration to be exported to the EU are expected to increase sharply For Better Chemically Yours Chemical Management Expert Group 4
5 1. Background : Overcoming EU REACH Regulation After with Toolbox : EU CHN KOR JPN Can USA Mex There is a pressing and urgent need for a tool to overcome the anticipated EU-REACH regulatory barriers and the bottleneck effects resulting from the nanomaterials and products industry. For Better Chemically Yours Chemical Management Expert Group 5
6 1. Background : Need for International Cooperation Need for International Cooperation - The EU plays a leading role in regulating the safety of chemicals and nanomaterials. Therefore, by establishing a network through joint research with EU research groups such as the consortium, we will be able to proactively respond to international standardization and new regulatory trends in ISO TC 229, OECD WPMN, and ECHA led by EU researchers. It is absolutely necessary to hold it. - In order for domestic companies to participate in the project as a partner and to secure the right to use final products and to commercialize them later, they actively contribute to the development of original technologies such as WP1 & WP2 at a research institute with original technology development capability (Hanyang Univ.) And an international cooperation strategy that enables domestic participating companies to commercialize the final products (expert system, education / training / consulting service contents) derived from WP3 & WP4. For Better Chemically Yours Chemical Management Expert Group 6
7 2. Objectives and Contents Measurable key parameters Online SOPs Video protocols Access to key relevant data Market? Material? Tonnage? EU Graphene Oxide 1 ton/year Toolbox Training service for nanomaterial characterization Consulting service for Fit for purpose characterization Expert system that optimizes various nanosafety related contents related to measurement analysis, test guideline, related data, registration of nanomaterials and products, permission, and markings to user needs Consulting service for nanomaterial /nanoproduct registrations Access to state-of-art analytical techniques For Better Chemically Yours Chemical Management Expert Group 7
8 3. Consortium H2020 Proposal Call NMBP Participated in 28 organizations in 10 countries including England, Austria, Switzerland, Germany and Korea final Selection Total 13,120,061 / year Focus on SMI participation and international cooperation For Better Chemically Yours Chemical Management Expert Group 8
9 3. Consortium : Network Major research groups for nanosafety in EU International standardization and regulatory bodies related to nanosafety For Better Chemically Yours Chemical Management Expert Group 9
10 3. Consortium : Concept NanoMILE NanoLYSE & NanoDefine NanoFASE NANoREG I&II enanomapper OECD & ECHA Toolbox Building Method Innovation Optimisation & benchmarking Streamlining of workflow Guidance & Decision trees Online SOPs & Reliable key descriptors video protocols Efficient fit for purpose characterisation Training cascade concept Training core cohort experts Community training 3 EU locations Roll-out online on-demand training and proficiency tools Data warehouse building Data gathering from other projects Data management system & ontology Phase 1 Phase 2 Phase 3 Data Warehouse & provisioning toolbox Skilled/proficient Easy access to key endusers relevant data Increased product confidence including on market processes For Better Chemically Yours Chemical Management Expert Group 10
11 WP7: Management & Coordination WP6: Dissemination & Collaborations 3. Consortium : Working Packages Delivering Anayltical Excelence WP1 WP1: Analytical innovation WP2: Analytical optimisation WP2 WP5 WP3 WP4 WP6 WP3: Method benchmarking & training WP4: Linking ontology & methodology WP5: Quality assurance risk assessment WP4 For Better Chemically Yours Chemical Management Expert Group 11
12 3. Consortium : Participation WPs WP4 : Linking ontology & methodology WP3 : Benchmarking & Training WP2 : Analytical Optimization WP1 : Analytical Innovations For Better Chemically Yours Chemical Management Expert Group 12
13 3. Consortium : Participating Domestic Institutions Phase 1 Phase 2 Phase 3 Toolbox Building Method Innovation Optimisation & benchmarking Streamlining of workflow Guidance & Decision trees HYU Contribution - Application of Synchrotron-based Soft X-ray Spectro-microscopy analytical technology development - Participated in Round Robin Test, an international collaboration of optimized analytical technology - Participate in making decision tree for nanomaterial analysis For Better Chemically Yours Chemical Management Expert Group 13
14 3. Consortium : Participation WPs - Institutions Microfluidic sample preparation On-line size separation/ surface characterization ToF-SIMS for bionano interactions CE for corona characterization QCM-D for corona monitoring Etc. WP3 : Benchmarking & Training WP2 : Analytical Optimization Wide-Area illumination Raman Spectroscopy Microfluidic sample prep. & delivery system (LA)-SP-TOF-ICP-MS Reactivity assay ona-chip Integration of AFM/Raman/Confoc al FFF Sample prep./intro. system Integration of NTA- FFF Etc. WP1 : Analytical Innovations Application of Soft X-ray Spectromicroscopic techniques for the chemical imaging of nanomaterials in biological, environmental & product matrix For Better Chemically Yours Chemical Management Expert Group 14
15 3. Consortium : Participating Domestic Institutions Data Warehouse Building TO21 Contribution Phase 1 Phase 2 Phase 3 Data gathering Data management system & ontology Data Warehouse & provisioning toolbox - Nanosafety DB development - Development of standardized data template - Extended development on Ontology - Nanosafety DB management system development - Consist of data warehouse - Development nanosafety decision making expert system For Better Chemically Yours Chemical Management Expert Group 15
16 3. Consortium : Participating Domestic Institutions WP4 : Linking ontology & methodology WP3 : Benchmarking & Training WP2 : Analytical Optimization WP1 : Analytical Innovations For Better Chemically Yours Chemical Management Expert Group 16
17 3. Consortium : Participating Domestic Institutions Phase 1 Phase 2 Training Cascade Concept Training Core Cohort Expert Community Training 3 EU location TO21 Contribution - Participated in Core Cohort Expert - Education for practitioners in Asia Phase 3 Roll-out online on-demand Training and Proficiency Tools - Korean online training and Proficiency Tool For Better Chemically Yours Chemical Management Expert Group 17
18 3. Consortium : Participating Domestic Institutions WP6 WP4 : Dissemination : Linking & Collaborations ontology & methodology WP3 : Benchmarking & Training WP2 : Analytical Optimization WP1 : Analytical Innovations For Better Chemically Yours Chemical Management Expert Group 18
19 4. Progress with Overseas Institutions Development - Commercialization technology promotion and external cooperation activities - Promotion of One Stop Solution for dissemination and diffusion of technology development - Designing networking system with and international organizations - Industrial support activities and program development - Public relations technology promotion in Asia Remarks - Promote project to domestic experts and advisors through S2nano Workshop - OpenTox - S2nano Workshop and Coordinator Prof. Eva and WP4 Coordinator Dr. Hardy invited to Korea - Kick-off meeting, General Assembly Meeting and Networking For Better Chemically Yours Chemical Management Expert Group 19
20 4. Progress with Overseas Institutions S 2 NANO Workshop2017Nov November 2~3 th, 2017 Venus room, SOL BEACH Samcheok S2NANO Workshop (2017.Jan. & 2017.Nov.) were held to invite domestic and overseas consultants such as KIST-Europe, douglas- Connect to promote technical cooperation on nanosafety For Better Chemically Yours Chemical Management Expert Group 20
21 4. Progress with Overseas Institutions -OpenTox-S2Nano Workshop ( ) The entire Consortium Coordinator, Prof. Eva Valsami-Jones and WP4 Coordinator, Barry Hardy visits South Korea and discusses specific research plans in the future For Better Chemically Yours Chemical Management Expert Group 21
22 4. Progress with Overseas Institutions Kick-Off Meeting, General Assembly meeting attendance and networking - Kick-off Meeting : Jan. Birmingham Univ., U.K. - General Assembly Meeting : Sept. Birmingham Univ., U.K. - Hanyang Univ. and TO21 researchers attended - To establish a close cooperation network with consortium participating organizations Kick-off Meeting, General Assembly Meeting, For Better Chemically Yours Chemical Management Expert Group 22
23 4. Progress with Overseas Institutions Progress with Overseas Institutions - The General Assembly Meeting, held every 6 months, was attended by domestic researchers and conducted regular exchanges with overseas researchers - WP2 : Participation in the regular WP2 Teleconference and participation in the International Round Robin Test - WP4 : The TO21 development team will collaborate with Douglas-Connect through a Teleconference and a visit to Basel, Switzerland to jointly develop the Toolbox - WP6 : The NanoSafety Training Session will be held with researchers at the OpenTox Asia Conference, Scheduled to be held in Tokyo in May 2018, to provide a forum for exchange between EU and Asian researchers For Better Chemically Yours Chemical Management Expert Group 23
24 Thank you!
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