SciFinder introduction and a view behind the scene how this tool is made

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1 SciFinder introduction and a view behind the scene how this tool is made

2 SciFinder is the most comprehensive, highestquality chemistry research tool, which saves you time and money Industry leader in comprehensiveness, timeliness and quality Content expertly curated by the best trained scientists Can be used for a wide variety of scientific research needs Powerful and easy to use

3 The disclosure of worldwide research continues to accelerate and SciFinder keeps up with the pace

4 In the last 12 months alone, CAS has actively curated millions of content types Content References Citations Organic/Inorganic Substances Reactions Commercially available products Regulated chemicals March M 391M 85M 71M 65M 309K Markush structures 1,027K March M 436M 94M 78M 100M 343K 1,074K

5 We just registered the 100 millionth small compound

6 Overall content growth is impressive but does not tell the whole story More than 1M experimental reaction procedures were added bringing the total to over 6M Procedures now included from Springer and Thieme Verlag journals > 22,000 heteroatom NMR added bringing the total to 1.3M experimental spectra >4.5M experimental properties Over 85,000 reactions from evaluated reference works were added from Thieme s Science of Synthesis and Wiley s Encyclopedia of Reagents for Organic Synthesis and Organic Reactions (EROS) Over 1,800 protein names and common synonyms were added to enhance SciFinder s search indices Coverage of dissertations was enhanced with Ph.D. dissertations from China

7 Peeling back a layer provides insight into where research is disclosed; languages highlight breadth of global research Discipline areas 61% not in traditional chemistry Disclosure types 35% not published in journals Dissertation Conferences Technical reports Book announcements Macromolecular Organic Patent Journal Applied Phys., Inorg.& Anal. Biochemistry Original publication languages 35% not published in English German Japanese Russian French Spanish Chinese English

8 Indexing of your paper in SciFinder Copyright 2013 American Chemical Society. All rights reserved. 8

9 Indexing of your paper in SciFinder Copyright 2013 American Chemical Society. All rights reserved. 9

10 More than 1000 editorial analysts at CAS identify and extract the disclosed chemistry

11 July 30, 2015 From published patent to completed indexing in SciFinder: 15 days Dr. Mark Willi from CAS completes substance indexing 15 days after WIPO publishes the patent CAS chemist analysis of single PCT application 917 indexed compounds from Examples and Claims 576 new compounds added to CAS REGISTRY 613 single-step reactions 5,394 reactions with multiple steps 1,029 reaction participants MARPAT Markush structure with 2,119 substituent definitions 11 Copyright 2010 American Chemical Society. All rights reserved.

12 CAS scientists find details, like the structure data below, that others miss CAS RN

13 More details on the technology of SciFinder? See these two YouTube videos Copyright 2013 American Chemical Society. All rights reserved. 13

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