SciFinder The choice for chemistry research
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1 SciFinder The choice for chemistry research October 25 th 28 th, 2016 Bucharest, Romania Veli-Pekka Hyttinen ACS International Ltd Tetiana Khristova ACS International Ltd CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 1
2 Chemical Abstracts Service The leading global source of chemical information for scientific and patent research CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 2
3 Renowned scientists trust SciFinder for research in scientific disciplines beyond traditional chemistry SciFinder, in the past, had the reputation of being primarily chemistry-focused, but this is no longer the case. Dr. Nick Terrett Chief Scientific Officer of Ensemble Therapeutics In fact, SciFinder covers a multitude of different scientific fields. It covers chemistry; it covers biology and pharmacology. And from my perspective in drug discovery, importantly, it covers many other branches of the life sciences. I use it as much for biology as I do for chemistry. CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 3
4 CAS informs your research by providing comprehensive coverage of science disclosed in a variety of scientific disciplines, Conferences Technical publications and languages Discipline areas 61% not in traditional chemistry Macromolecular Organic Disclosure types 35% not published in journals Dissertation Patent Journal reports Book announcements German Russian French Spanish Applied Biochemistry Japanese Phys., Inorg.& Anal. Chinese English Original publication languages 35% not published in English CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 4
5 CAS analyzes the world s disclosed research to keep SciFinder the most valuable tool supporting your organization s research enterprise 44 million+ Literature References Plus integrated access to 25 million records in the MEDLINE database from the U.S. National Library of Medicine gives you access to the world s most authoritative disclosed chemistry and related sciences content. 66 million+ protein and nucleic acid sequences 63 Patent Authorities 25% more than any other scientific information provider 121million+ uniquely identified organic and inorganic substances Ranging from the largest proteins to the smallest molecules Data as of March 2016 CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 5
6 SciFinder saves you time by delivering valuable information to advance your research PatentPak TM Efficient access to the most requested patents in SciFinder 6.8 million+ experimental reaction procedures with 0.9 million added in the last year alone! 1.4 million experimental spectra >100,000 protons and carbon-13 NMR additions Addition of >73,000 single-step reactions and their experimental procedures from 1,450 dissertations in SORD > 4.5 million experimental properties New layout and format greatly improves readability and user-friendliness of substance detail pages MethodsNow TM Immediate access to detailed experimental methods CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 6
7 The rapid acceleration of disclosed research drives content growth in the CAS databases Information added to the CAS databases annually since ,000,000 2,000, ,000,000 1,800,000 90,000,000 1,600,000 80,000,000 70,000,000 60,000,000 50,000,000 40,000,000 30,000,000 1,400,000 1,200,000 1,000, , ,000 20,000, ,000 10,000, , Substances Reactions References Indexed Patents CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 7
8 CAS scientists curate scientific information using standardized terminology to help researchers quickly find the most relevant search results in SciFinder Indexing in other search tools can be unpredictable less-detailed non-existent CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 8
9 Categorize and analyze options make it easy to find relevant information CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 9
10 CAS scientists analyze, summarize and make scientific information accessible to colleagues worldwide Source Selection Document Indexing Reaction Indexing Markush Indexing Authority Processing Proprietary, standardized indexing in CAS databases ensures consistent, comprehensive search results. CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 10
11 CAS scientists find the chemistry, and save you time! CAS RN CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 11
12 SciFinder allows you to explore and analyze the breadth of CAS content so you can be more effective in your work Stay current in your field and keep track of competition Quickly find and analyze information (research topic, structure, reaction) Share ideas with colleagues and collaborators CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 12
13 Unlike its competitors, CAS covers patents in many languages, with enhanced translations CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 13
14 Increasingly, new compounds in the literature are first disclosed in patents 100% Percentage of New Compounds from Patents Percentage of Total 80% 60% 40% 20% 00% 77% 14% Year CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 14
15 Instant access to searchable full-text patents from major patent offices around the world Patent family coverage in multiple languages Substance location mapping Interactive viewer with built-in SciFinder search functionality Secure and confidential patent research Daily updates 8 mill patents from 31 countries ACS / Proprietary and Confidential / Do Not Distribute 15
16 SciFinder PatentPak Patent Family information CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 16
17 CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 17
18 CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 18
19 MethodsNow TM is a complete CAS solution Largest single collection of methods information Addresses core chemistry markets CAS-quality indexing and new, value-add templating of key methods from important full-text sources Covers both synthetic and analytical researcher needs ACS / Proprietary and Confidential / Do Not Distribute 19
20 So what exactly is MethodsNow? Largest single collection of methods information Addresses core chemistry markets CAS-quality indexing and new, value-add templating of key methods from important full-text sources Covers 2+ million synthetic step-by-step protocols from 2000 onwards, and 200,000+ analytical methods focusing in Pharma, Ag, and chemicals Details for analytical researchers such as matrix, analyte, instrumentation and comparison capabilities ACS / Proprietary and Confidential / Do Not Distribute 20
21 One product, two interfaces Research showed that users interested in synthetic methods were often already in SciFinder, but analytical scientists often weren t (though they might be familiar with it) Synthetic chemist looking for great methods? They are in SciFinder. Analytical scientist just looking for great methods? A new, easy to use interface just for you. ACS / Proprietary and Confidential / Do Not Distribute 21
22 MethodsNow Analysis: A Workflow Solution Powered By Excellent Content MethodsNow journal content Content from years present Number of methods >220,000 Content coverage Based on exis;ng CAplus content in the biochemical, applied, analy;cal CAS sec;ons Focus Example journal ;tles Language Small molecule-centric Food Chemistry, Journal of Chromatography A and B, Journal of Agricultural and Food Chemistry, Talanta, Analy;ca Chimica Acta English only CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 22
23 MethodsNow Analysis: Main Categories Method categories Primary content in these categories ac;ve-pharmaceu;cal-ingredient bioassay biomolecule-isola;on-assay bioorganism-isola;on-assay element-detec;on environmental-analysis food-analysis forensic-analysis natural-product-isola;on-analysis organic-compound-analysis pes;cide-residue-analysis trace-element-analysis water-wastewater-sludge-analysis Pharmacology, toxicology, SAR, analysis of drugs Pharmacology, toxicology, biochemical methods Biochemical methods, mammalian hormones Biochemical gene;cs Inorganic analy;cal chemistry Essen;al oils/cosme;cs Addi;ves, food processing, contaminants, GMO Toxicology Analysis of drugs Organic analy;cal chem. Food, feed, toxicology, agrochemical bioregulators Inorganic analy;cal chemistry, benzene Chemical water analysis (i.e. contaminants in water) CAS is a division of the American Chemical Society. Copyright 2015 American Chemical Society. All rights reserved. 23
24 MethodsNow Analytical Scientist Interface ACS / Proprietary and Confidential / Do Not Distribute 24
25 Specify one or many advanced search fields ACS / Proprietary and Confidential / Do Not Distribute 25
26 ACS / Proprietary and Confidential / Do Not Distribute 26
27 ACS / Proprietary and Confidential / Do Not Distribute 27
28 ACS / Proprietary and Confidential / Do Not Distribute 28
29 ACS / Proprietary and Confidential / Do Not Distribute 29
30 ACS / Proprietary and Confidential / Do Not Distribute 30
31 ACS / Proprietary and Confidential / Do Not Distribute 31
32 ACS / Proprietary and Confidential / Do Not Distribute 32
33 MethodsNow synthetic chemistry content sources Content from years Number of protocols Content Coverage Source Focus Example journal ;tles Language present 2.1 million; 3 million later this year Small molecule synthesis 180+ journals ;tles including new coverage from Wiley, RSC and Elsevier in addi;on to ACS, Springer, Taylor&Francis, WO patents (2010-present) Organic Le[ers, Catalysis Le[ers, Journal of Coordina;on Chemistry, Journal of Medicinal Chemistry, Journal of the American Chemical Society, Angewandte Chemie, Tetrahedron, Chemical Science English only ACS / Proprietary and Confidential / Do Not Distribute 33
34 MethodsNow Synthetic Chemist Interface ACS / Proprietary and Confidential / Do Not Distribute 34
35 SciFinder has the largest collection of experimental procedures for reactions It is our most popular feature, but you ve told us we can do more ACS / Proprietary and Confidential / Do Not Distribute 35
36 ACS / Proprietary and Confidential / Do Not Distribute 36
37 ACS / Proprietary and Confidential / Do Not Distribute 37
38 Chemisches Zentralblatt predates the introduction of Chemical Abstracts by almost 80 years Founded in 1830 to abstract chemistryrelated literature The only abstract journal until 1907 Published from Chronicles the birth of chemistry as a science Before 1800, chemistry was more alchemy (i.e. how to turn lead into gold) than actual science First Issue: Note, the name changed several times before 1856 CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 38
39 Why is Chemisches Zentralblatt so important? It covers the literature from an historically important era for chemistry Many authors covered by this publication formulated the theories and hypotheses that shaped the foundation of today s chemistry Mortiz Traube alcohol fermentation by enzymes Louis Pasteur microbial fermentation Niels Bohr Bohr model Albert Einstein theory of relativity Eilhard Mitscherling selenic acid Heinrich Rose Rediscovered, named Niobium Ernest Rutherford alpha and beta radioactivity CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 39
40 ChemZent TM in SciFinder makes this literature newly discoverable Covers chemical literature from 1830 to 1969 The first and oldest abstracts journal in chemistry (>3 million abstracts) The only comprehensive abstract journal available until 1907 German is translated to and searchable in English Substances and concepts are indexed from the German abstracts Structures and keywords are searchable Markers at the start of German abstracts can be displayed and printed Now integrated into SciFinder and available for purchase Completes and extends the comprehensive content in SciFinder Provides easy access to a valuable chemistry collection via a familiar CAS solution CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 40
41 ChemZent is available via subscription in SciFinder CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 41
42 CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 42
43 Veli-Pekka Hyttinen Regional Marketing Manager Central and Eastern Europe Tetiana Khristova Regional Marketing Manager Ukraine Connect with SciFinder Thank you!!! CAS is a division of the American Chemical Society. Copyright 2016 American Chemical Society. All rights reserved. 43
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