Information Retrieval: SciFinder

Transcription

1 Information Retrieval: SciFinder Second Edition DAMON D. RIDLEY School of Chemistry, The University of Sydney WI LEY A John \Viley and Sons, Ltd., Puhliratimt

2 Contents Preface xi 1 SciFinder : Setting the Scene ' I Just Want to Do a Quick and Simple Search an ' Databases Search Terms Narrowing Answers Precision; Broadening Answers Comprehension The SciFinder Way Getting the Initial Answers Beyond the Initial Display: CAPLUS and REGISTRY Beyond the Original Display: MEDLINE Post-processing: Analyze/Analysis Post-processing: Categorize Post-processing: Refine Broadening Answers: Get Substances, Get Reactions, Get Citing, and Get Cited Databases in SciFinder Looking Ahead 19 2 Databases in SciFinder CAS Bibliographic Database (CAPLUS) Content and Coverage Indexing in CAPLUS NLM Bibliographic Database (MEDLINE) CAS Substance Database (REGISTRY) CAS Chemical Reaction Database (CASREACT ) CAS Chemical Catalog Database (CHEMCATS ) CAS Regulatory Information Database (CHEMLIST ) Summar}, of Key Points 38 3 Explore by Research Topic Introduction How SciFinder Converts the Query to a List of Candidates Search Fields 41

3 vi Contents Candidates Notes an Terms Entered How Is a Concept Derived? Automatic Truncation Singulars, Plurals, Tenses (Part, Present, Future) Synonyms Phrases CAS Registry Numbers Choosing Candidates Working from the Reference Screen Keep Me Posted Search History Selecting, Saving, Printing, Exporting, and Sorting Records Link to Full Record and Link to Full Text Analyze References Refine References Analyze or Refine? Categorize Working from the Record Screen Applying Scientific Method to Information Retrieval Step 1. Conceptualize the Initial Search Query Step 2. Perform an Initial Search Step 3. Examine the Initial Answers Step 4. Revise Search Summary of Key Points 73 4 Explore by Chemical Substance Introduction Registration of Substances CAS Registry Numbers Policies for Substance Indexing Searching for Substances: The Alternatives Explore Substances: Chemical Structure Overview Drawing Structures Explore Substances: Exact search Explore Substances: Substance Identifier Explore Substances: Molecular Formula Examples of Applications of Searches by Molecular Formula Explore References: Research Topic Summary of Key Points 90 5 Substructure and Similarity Searching Introduction 91

4 Contents vii 5.2 Searching Substances: Substructure The Screening Issue Structure Is Too General The Resonance Issue The Tautomerism Issue Show Precision Analysis Locking Tools Additional Query Tools Additional Search Refinements Searching Structures: Working from the Initial Substance Answer Set Analysis of Substances Refine Substances Narrowing and Broadening Answers Similarity Search Further Examples of Show Precision Analysis Coordination Compounds and Salts Cyclic Hemiacetals and Hydroxycarbonyls; Pentavalent Phosphorus Additional Structure Query Options Exact Search Substructure Search Getting References Combining Explore Substances and Explore References Summary of Key Points Additional Search and Display Options Introduction Explore: Author Name Explore: Company Name Explore: Document Identifier Explore: Journal and Explore: Patent Getting Information from Bibliographie Records Get Substances Citations Further Issues with Finding Information an Substances Option (a). Starting with Explore References: Research Topic Option (b). Starting with Explore Substances Further Considerations Opportunities for MEDLINE Searchers Complimentarity of MEDLINE and CAPLUS Complimentarity of REGISTRY, MEDLINE, and CAPLUS The SciFinder Interface and Search Opportunities Searching for Substances in the Biological Sciences Nucleic Acids and Related Terms Proteins 140

5 viii Contents 6.10 Searching for Information on Polymers Summary of Key Points Searching for Information on Chemical Reactions Introduction Specific Search Options in CASREACT Reaction Search Strategies Explore Substances and Explore Reactions Using Functional Groups Retrosynthetic Analysis Searching for Reactions through Explore References: Research Topic Combining Structure, Reaction, Functional Group, and Keyword Terms Summary of Key Points 174 Appendix 1 Some SciFinder Resources 177 Appendix 2 CAS Roles in CAPLUS 179 Appendix 3 Some Basic Principles Used by SciFinder in the Interpretation of a Research Topic Query 181 Appendix 4 Registration of Substances 185 A4.1 Single-Component Substances 185 A4.1.1 Single Substances 185 A4.1.2 Elements, Ions, and Particles 186 A4.1.3 Isotopic Substances 187 A4.1.4 Stereoisomers 188 A4.1.5 Donor Bonds 189 A4.1.6 Intermediates 190 A4.2 Multicomponent Substances 192 A4.2.1 Salts 192 A4.2.2 Alloys 194 A4.2.3 Mixtures 196 A4.3 Metal Complexes 196 A4.3.1 cr-complexes 197 A r-Complexes 197 A4.4 Macromolecules 198 A4.4.1 Homopolymers 199 A4.4.2 Copolymers 199 A4.4.3 Structure Repeating Units 199 A4.4.4 Proteins 200 A4.4.5 Nucleic Acids and Related Substances 200

6 Contents ix A4.5 Other Cases 202 A4.5.1 Incompletely Defined Substances 202 A4.5.2 Minerals 204 A4.5.3 Records with `1\To References' 204 Appendix 5 Understanding Structure Searches 207 A5.1 The Resonance Issue 207 A5.2 The Tautomerism Issue 207 A5.3 Chain Lock Tool 208 A5.4 Ring Lock Tool 208 Appendix 6 Original Publication Discussed in Chapter 7, Section Index 211