Modeling endothelial glycocalyx and its interaction with blood flow
|
|
- Ariel Holly Stevens
- 5 years ago
- Views:
Transcription
1 Modeling endothelial glycocalyx and its interaction with blood flow Sofia Biagi PhD under the joint supervision of DdR Chaouqi Misbah LIPhy, Grenoble Prof. Francesco Sciortino Università Sapienza, Roma
2 Introduction BLOOD CIRCULATION MODEL one-kind particles in a simple newtonian liquid 1/11
3 Introduction BLOOD CIRCULATION MODEL one-kind particles in a simple newtonian liquid & geometry, elasticity of vessels, morphology of the endothelial surface layer 1/11
4 Introduction BLOOD CIRCULATION MODEL one-kind particles in a simple newtonian liquid & geometry, elasticity of vessels, morphology of the endothelial surface layer 1/11
5 Introduction in vivo in vitro For example: A. R. Pries, T. W. Secomb, Circ. Res. (1990) 2/11
6 Introduction Van den Berg, Vink, Spaan, Circ. Res. 92, 592 (2003) in vivo in vitro For example: A. R. Pries, T. W. Secomb, Circ. Res. (1990) GLYCOCALYX sweet shield Polymer brush, constituted by macromolecules (proteoglycans, hyaluronan, glycoproteins, ) attached to the endothelium 2/11
7 Introduction RELEVANCE: 3/11
8 Introduction RELEVANCE: glycocalyx lack or reduction!!! diseases e.g.: plaque formation in atherosclerosis M. Nieuwdorp et al., Curr. Opin. Lipid. 16, 507 (2005) 3/11
9 Introduction RELEVANCE: glycocalyx lack or reduction!!! diseases e.g.: plaque formation in atherosclerosis M. Nieuwdorp et al., Curr. Opin. Lipid. 16, 507 (2005) understanding polymer brush dynamics under flow e.g.: recent experiments on artificial polymer brushes in Grenoble L. Lanotte et al., Langmuir (2012)??? 3/11
10 OUTLINE 1. Choice of the numerical method 2. Polymer brush at equilibrium 3. Polymer brush under flow 4/11
11 OUTLINE 1. Choice of the numerical method 2. Polymer brush at equilibrium 3. Polymer brush under flow 4/11
12 Choice of the numerical method SIMPLE LIQUID AND LINEAR GRAFTED CHAINS 5/11
13 Choice of the numerical method SIMPLE LIQUID AND LINEAR GRAFTED CHAINS courtesy of L. Rovigatti DISSIPATIVE PARTICLE DYNAMICS (DPD) (coarse-graining of Molecular Dynamics) 5/11
14 Choice of the numerical method SIMPLE LIQUID AND LINEAR GRAFTED CHAINS courtesy of L. Rovigatti DISSIPATIVE PARTICLE DYNAMICS (DPD) (coarse-graining of Molecular Dynamics) hydrodynamic interactions explicit solvent 5/11
15 OUTLINE 1. Choice of the numerical method 2. Polymer brush at equilibrium 3. Polymer brush under flow 4/11
16 ρ Polymer brush at equilibrium At equilibrium conformational entropy excluded volume Milner et al., Macromolecules (1988) Deng et al., J. Fluid Mech. (2012) brush density profiles ρ(z) z varying the chain length n at same grafting density σ graft varying the grafting density σ graft at same chain length n (σ graft = 1.5) (n = 16) 6/11
17 ρ Polymer brush at equilibrium At equilibrium conformational entropy excluded volume Milner et al., Macromolecules (1988) Deng et al., J. Fluid Mech. (2012) brush density profiles ρ(z) z varying the chain length n at same grafting density σ graft varying the grafting density σ graft at same chain length n (σ graft = 1.5) (n = 16) the higher the volume fraction, the more step-like the density profile 6/11
18 OUTLINE 1. Choice of the numerical method 2. Polymer brush at equilibrium 3. Polymer brush under flow 4/11
19 Polymer brush under flow Under flow ( σ graft = 1.5 ) tilting compression (h b h eq )/h eq Wi < R ee x > ~Wi 0.76 (h b h eq )/h eq ~Wi 1.5 7/11
20 Polymer brush under flow Under flow ( σ graft = 1.5 ) tilting compression (h b h eq )/h eq Wi < R ee x > ~Wi 0.76 (h b h eq )/h eq ~Wi 1.5 no consensus on theories -even on the fact that the brush should swell or compress 7/11
21 Polymer brush under flow flow inversions 8/11
22 Polymer brush under flow flow inversions /11
23 Polymer brush under flow 45 9/11
24 Polymer brush under flow /11
25 Polymer brush under flow /11
26 Polymer brush under flow /11
27 Polymer brush under flow /11
28 Polymer brush under flow /11
29 Polymer brush under flow /11
30 Polymer brush under flow /11
31 Considerations which is the actual dynamics of those chains? 10/11
32 Considerations which is the actual dynamics of those chains? stretching - elongation - recoiling M. Müller and C. Pastorino, EPL (2008) Léonforte et al., Cond. Matt. (2011) 10/11
33 Considerations which is the actual dynamics of those chains? stretching - elongation - recoiling M. Müller and C. Pastorino, EPL (2008) Léonforte et al., Cond. Matt. (2011) different concavities well-separated Wi ranges /11
34 Considerations which is the actual dynamics of those chains? stretching - elongation - recoiling M. Müller and C. Pastorino, EPL (2008) Léonforte et al., Cond. Matt. (2011) different concavities well-separated Wi ranges but more than one explication 10/11
35 Considerations NOISE ENTROPY HYDRODYNAMIC SHEAR FENE no periodicity in the cyclic motion collective effects? Wi correlation between velocity and position of monomers periodicity resonance? collective effects? 11/11
36 Next steps: Explanation for the scaling behaviors Polydisperse brush Interaction with solid particles Interaction with RBCs 11/11
37 Next steps: Explanation for the scaling behaviors Polydisperse brush Interaction with solid particles Interaction with RBCs Thank you 11/11
Chapter 1 Introduction
Chapter 1 Introduction This thesis is concerned with the behaviour of polymers in flow. Both polymers in solutions and polymer melts will be discussed. The field of research that studies the flow behaviour
More informationSmoothed Dissipative Particle Dynamics: theory and applications to complex fluids
2015 DPD Workshop September 21-23, 2015, Shanghai University Smoothed Dissipative Particle Dynamics: Dynamics theory and applications to complex fluids Marco Ellero Zienkiewicz Centre for Computational
More informationProteins polymer molecules, folded in complex structures. Konstantin Popov Department of Biochemistry and Biophysics
Proteins polymer molecules, folded in complex structures Konstantin Popov Department of Biochemistry and Biophysics Outline General aspects of polymer theory Size and persistent length of ideal linear
More informationFlow-induced deformation of droplets, vesicles and red blood cells
COST MP1305 - Flowing matter 2014 Instituto para a Investigação Interdisciplinar, Universidade de Lisboa 15-17 December 2014 Flow-induced deformation of droplets, vesicles and red blood cells Stefano Guido
More informationDissipative Particle Dynamics: Foundation, Evolution and Applications
Dissipative Particle Dynamics: Foundation, Evolution and Applications Lecture 4: DPD in soft matter and polymeric applications George Em Karniadakis Division of Applied Mathematics, Brown University &
More informationDroplet transport in a nanochannel coated by. hydrophobic semiflexible polymer brushes: the. effect of chain stiffness
Droplet transport in a nanochannel coated by arxiv:1710.02414v2 [cond-mat.soft] 17 Oct 2017 hydrophobic semiflexible polymer brushes: the effect of chain stiffness K. Speyer and C. Pastorino, Departamento
More informationExplaining and modelling the rheology of polymeric fluids with the kinetic theory
Explaining and modelling the rheology of polymeric fluids with the kinetic theory Dmitry Shogin University of Stavanger The National IOR Centre of Norway IOR Norway 2016 Workshop April 25, 2016 Overview
More informationColloidal Suspension Rheology Chapter 1 Study Questions
Colloidal Suspension Rheology Chapter 1 Study Questions 1. What forces act on a single colloidal particle suspended in a flowing fluid? Discuss the dependence of these forces on particle radius. 2. What
More informationViscoelastic Flows in Abrupt Contraction-Expansions
Viscoelastic Flows in Abrupt Contraction-Expansions I. Fluid Rheology extension. In this note (I of IV) we summarize the rheological properties of the test fluid in shear and The viscoelastic fluid consists
More informationAPMA 2811T. By Zhen Li. Today s topic: Lecture 3: New Methods beyond traditional DPD. Sep. 22, Division of Applied Mathematics, Brown University
Today s topic: APMA 2811T Dissipative Particle Dynamics Instructor: Professor George Karniadakis Location: 170 Hope Street, Room 118 Time: Thursday 12:00pm 2:00pm Dissipative Particle Dynamics: Foundation,
More informationPerfect mixing of immiscible macromolecules at fluid interfaces
Perfect mixing of immiscible macromolecules at fluid interfaces Sergei S. Sheiko, 1* Jing Zhou, 1 Jamie Boyce, 1 Dorota Neugebauer, 2+ Krzysztof Matyjaszewski, 2 Constantinos Tsitsilianis, 4 Vladimir V.
More informationarxiv: v2 [cond-mat.soft] 31 Jul 2007
Comparison of Dissipative Particle Dynamics and Langevin thermostats for out-of-equilibrium simulations of polymeric systems C. Pastorino, T. Kreer, M. Müller, and K. Binder Departamento de Física, Centro
More informationAnnual Report for Research Work in the fiscal year 2006
JST Basic Research Programs C R E S T (Core Research for Evolutional Science and Technology) Annual Report for Research Work in the fiscal year 2006 Research Area : High Performance Computing for Multi-scale
More informationIntroduction to Computer Simulations of Soft Matter Methodologies and Applications Boulder July, 19-20, 2012
Introduction to Computer Simulations of Soft Matter Methodologies and Applications Boulder July, 19-20, 2012 K. Kremer Max Planck Institute for Polymer Research, Mainz Overview Simulations, general considerations
More informationLessons learned from the exquisite design of the endothelial surface glycocalyx and their amazing applications
Lessons learned from the exquisite design of the endothelial surface glycocalyx and their amazing applications Q. Wu, Y. Andreopoulos & S. Weinbaum Departments of Biomedical and Mechanical Engineering
More informationPHASE TRANSITIONS IN SOFT MATTER SYSTEMS
OUTLINE: Topic D. PHASE TRANSITIONS IN SOFT MATTER SYSTEMS Definition of a phase Classification of phase transitions Thermodynamics of mixing (gases, polymers, etc.) Mean-field approaches in the spirit
More informationChristel Hohenegger A simple model for ketchup-like liquid, its numerical challenges and limitations April 7, 2011
Notes by: Andy Thaler Christel Hohenegger A simple model for ketchup-like liquid, its numerical challenges and limitations April 7, 2011 Many complex fluids are shear-thinning. Such a fluid has a shear
More informationShear rheology of polymer melts
Shear rheology of polymer melts Dino Ferri dino.ferri@versalis.eni.com Politecnico Alessandria di Milano, 14/06/2002 22 nd October 2014 Outline - Review of some basic rheological concepts (simple shear,
More informationExperimental Soft Matter (M. Durand, G. Foffi)
Master 2 PCS/PTSC 2016-2017 10/01/2017 Experimental Soft Matter (M. Durand, G. Foffi) Nota Bene Exam duration : 3H ecture notes are not allowed. Electronic devices (including cell phones) are prohibited,
More informationOrigins of Mechanical and Rheological Properties of Polymer Nanocomposites. Venkat Ganesan
Department of Chemical Engineering University of Texas@Austin Origins of Mechanical and Rheological Properties of Polymer Nanocomposites Venkat Ganesan $$$: NSF DMR, Welch Foundation Megha Surve, Victor
More information좋은아침입니다 (Cho Eun Achim Yip Ni Da) (Jeo Reul Cho Dae Hae Joo
좋은아침입니다 (Cho Eun Achim Yip Ni Da) 저를초대해주셔서감사합니다 (Jeo Reul Cho Dae Hae Joo Seuh Seo, Kam Sa Hap Ni Da) PLEASE JOIN US 13 TH INTERNATIONAL CONGRESS OF BIORHEOLOGY and 6 TH INTERNATIONAL CONFERENCE ON CLINICAL
More informationSwelling and Collapse of Single Polymer Molecules and Gels.
Swelling and Collapse of Single Polymer Molecules and Gels. Coil-Globule Transition in Single Polymer Molecules. the coil-globule transition If polymer chains are not ideal, interactions of non-neighboring
More informationMechanical modeling of a developing tissue as both continuous and cellular
Mechanical modeling of a developing tissue as both continuous and cellular Modélisation mécanique d'un tissu en développement : en quoi un matériau cellulaire diffère d'un matériau continu Cyprien Gay
More informationInterfacial forces and friction on the nanometer scale: A tutorial
Interfacial forces and friction on the nanometer scale: A tutorial M. Ruths Department of Chemistry University of Massachusetts Lowell Presented at the Nanotribology Tutorial/Panel Session, STLE/ASME International
More informationNumerical simulation of rheology of red blood cell rouleaux in microchannels
PHYSICAL REVIEW E 79, 41916 9 Numerical simulation of rheology of red blood cell rouleaux in microchannels T. Wang, 1 T.-W. Pan, 1 Z. W. Xing, 2 and R. Glowinski 1 1 Department of Mathematics, University
More informationSimulation of Coarse-Grained Equilibrium Polymers
Simulation of Coarse-Grained Equilibrium Polymers J. P. Wittmer, Institut Charles Sadron, CNRS, Strasbourg, France Collaboration with: M.E. Cates (Edinburgh), P. van der Schoot (Eindhoven) A. Milchev (Sofia),
More informationSOME DYNAMICAL FEATURES OF THE TURBULENT FLOW OF A VISCOELASTIC FLUID FOR REDUCED DRAG
SOME DYNAMICAL FEATURES OF THE TURBULENT FLOW OF A VISCOELASTIC FLUID FOR REDUCED DRAG L. Thais Université de Lille Nord de France, USTL F9 Lille, France Laboratoire de Mécanique de Lille CNRS, UMR 817
More informationMacromolecular Crowding
Macromolecular Crowding Keng-Hwee Chiam Mathematical and Theoretical Biology Group Goodsell (1994) Macromolecular Crowding, Oct. 15, 2003 p.1/33 Outline What: introduction, definition Why: implications
More informationPart III. Polymer Dynamics molecular models
Part III. Polymer Dynamics molecular models I. Unentangled polymer dynamics I.1 Diffusion of a small colloidal particle I.2 Diffusion of an unentangled polymer chain II. Entangled polymer dynamics II.1.
More informationPharmaceutical compounding I Colloidal and Surface-Chemical Aspects of Dosage Forms Dr. rer. nat. Rebaz H. Ali
University of Sulaimani School of Pharmacy Dept. of Pharmaceutics Pharmaceutical Compounding Pharmaceutical compounding I Colloidal and Surface-Chemical Aspects of Dosage Forms Dr. rer. nat. Rebaz H. Ali
More informationVesicle micro-hydrodynamics
Vesicle micro-hydrodynamics Petia M. Vlahovska Max-Planck Institute of Colloids and Interfaces, Theory Division CM06 workshop I Membrane Protein Science and Engineering IPAM, UCLA, 27 march 2006 future
More informationSimulations of Self-Assembly of Polypeptide-Based Copolymers
East China University of Science and Technology Theory, Algorithms and Applications of Dissipative Particle Dynamics Simulations of Self-Assembly of Polypeptide-Based Copolymers Jiaping LIN ( 林嘉平 ) East
More informationChemistry C : Polymers Section. Dr. Edie Sevick, Research School of Chemistry, ANU. 4.0 Polymers at interfaces
Chemistry C302-2006: Polymers Section Dr. Edie Sevick, Research School of Chemistry, ANU 4.0 Polymers at interfaces In this section, we begin to investigate the conformation at interfaces, including multiplechains
More informationMonte Carlo Simulations of the Hyaluronan-Aggrecan Complex in the Pericellular Matrix
Monte Carlo Simulations of the Hyaluronan-Aggrecan Complex in the Pericellular Matrix Marcel Hellmann BIOMS Group Cellular Biophysics, Deutsches Krebsforschungszentrum (DKFZ) Theoretical Biophysics Group,
More informationModulation of Electroosmotic Flow by Neutral Polymers
Modulation of Electroosmotic Flow by Neutral Polymers Rui Qiao* and Ping He Department of Mechanical Engineering, Clemson UniVersity, Clemson, South Carolina 29634 ReceiVed October 16, 2006. In Final Form:
More informationLecture 5: Macromolecules, polymers and DNA
1, polymers and DNA Introduction In this lecture, we focus on a subfield of soft matter: macromolecules and more particularly on polymers. As for the previous chapter about surfactants and electro kinetics,
More informationMargination of a leukocyte in a model microvessel
Margination of a leukocyte in a model microvessel Jonathan B. Freund Mechanical Science & Engineering University of Illinois at Urbana-Champaign J. B. Freund p.1/40 Inflammation Response Leukocyte (white
More informationRheological properties of polymer melt between rapidly oscillating plates: - an application of multiscale modeling -
http://multiscale.jp Rheological properties of polymer melt between rapidly oscillating plates: - an application of multiscale modeling - Ryoichi Yamamoto and Shugo Yasuda Dept. Chemical Engineering, Kyoto
More informationRandomly Triangulated Surfaces as Models for Fluid and Crystalline Membranes. G. Gompper Institut für Festkörperforschung, Forschungszentrum Jülich
Randomly Triangulated Surfaces as Models for Fluid and Crystalline Membranes G. Gompper Institut für Festkörperforschung, Forschungszentrum Jülich Motivation: Endo- and Exocytosis Membrane transport of
More informationQuiz 1 Introduction to Polymers
090109 Quiz 1 Introduction to Polymers In class we discussed the definition of a polymer first by comparing polymers with metals and ceramics and then by noting certain properties of polymers that distinguish
More informationSupplementary Information for: Controlling Cellular Uptake of Nanoparticles with ph-sensitive Polymers
Supplementary Information for: Controlling Cellular Uptake of Nanoparticles with ph-sensitive Polymers Hong-ming Ding 1 & Yu-qiang Ma 1,2, 1 National Laboratory of Solid State Microstructures and Department
More informationStatistical Mechanics and Thermodynamics of Small Systems
Statistical Mechanics and Thermodynamics of Small Systems Luca Cerino Advisors: A. Puglisi and A. Vulpiani Final Seminar of PhD course in Physics Cycle XXIX Rome, October, 26 2016 Outline of the talk 1.
More informationModeling Strong Extensional Flows of Polymer Solutions and Melts
Modeling Strong Extensional Flows of Polymer Solutions and Melts Antony N. Beris CSCAMM Workshop Multiscale Modeling and Simulation of Complex Fluids April 19, 27 Acknowledgements: Dr. Joydeep Mukherjee,
More informationMesoscopic simulation of DNA using Smoothed Dissipative Particle Dynamics
Technische Universität München Lehrstuhl für Aerodynamik und Strömungsmechanik Mesoscopic simulation of DNA using Smoothed Dissipative Particle Dynamics Sergey Litvinov Vollständiger Abdruck der von der
More informationPolymer Dynamics and Rheology
Polymer Dynamics and Rheology 1 Polymer Dynamics and Rheology Brownian motion Harmonic Oscillator Damped harmonic oscillator Elastic dumbbell model Boltzmann superposition principle Rubber elasticity and
More informationSolid-fluid mixtures and hydrogels
Chapter 6 Solid-fluid mixtures and hydrogels Ahydrogelisapolymernetworkfilledwithasolvent(fluid). Thismeansthatitcanchange volume by means of absorbing (or expelling) solvent. A dry gel can change its
More informationStructuring of hydrophobic and hydrophilic polymers at interfaces Stephen Donaldson ChE 210D Final Project Abstract
Structuring of hydrophobic and hydrophilic polymers at interfaces Stephen Donaldson ChE 210D Final Project Abstract In this work, a simplified Lennard-Jones (LJ) sphere model is used to simulate the aggregation,
More informationConformational behaviors of a charged-neutral star micelle in salt-free solution
PAPER www.rsc.org/pccp Physical Chemistry Chemical Physics Conformational behaviors of a charged-neutral star micelle in salt-free solution Mingge Deng, ab Ying Jiang, ab Xuejin Li,* ab Lei Wang ab and
More informationRheology of polymer brush under oscillatory shear flow studied by nonequilibrium Monte Carlo simulation
THE JOURNAL OF CHEMICAL PHYSICS 123, 144904 2005 Rheology of polymer brush under oscillatory shear flow studied by nonequilibrium Monte Carlo simulation Shichen Ji and Jiandong Ding a Key Laboratory of
More informationContact lubrication in human articular joints: The role of mucinous glycoproteins
Contact lubrication in human articular joints: The role of mucinous glycoproteins Bruno Zappone Italian National Research Council - CNR Institute for Physical- Chemical Processes - IPCF Liquid Crystal
More informationImproved model of nonaffine strain measure
Improved model of nonaffine strain measure S. T. Milner a) ExxonMobil Research & Engineering, Route 22 East, Annandale, New Jersey 08801 (Received 27 December 2000; final revision received 3 April 2001)
More informationEffect of Glycocalyx on Red Blood Cell Motion in Capillary Surrounded by Tissue
Available at http://pvamu.edu/aam Appl. Appl. Math. ISSN: 9-9466 Vol. 4, Issue (June 009) pp. 4 48 (Previously, Vol. 4, No. ) Applications and Applied Mathematics: An International Journal (AAM) Effect
More informationMicro and Macro in the Dynamics of Dilute Polymer Solutions
Micro and Macro in the Dynamics of Dilute Polymer Solutions Ravi Prakash Jagadeeshan Complex Fluid Mechanics Closed form equations Constitutive Equations Stress Calculator Simulations (BDS etc) Homogeneous
More informationNonlinear stability of steady flow of Giesekus viscoelastic fluid
Nonlinear stability of steady flow of Giesekus viscoelastic fluid Mark Dostalík, V. Průša, K. Tůma August 9, 2018 Faculty of Mathematics and Physics, Charles University Table of contents 1. Introduction
More informationEffects of interaction between nanopore and polymer on translocation time
Effects of interaction between nanopore and polymer on translocation time Mohammadreza Niknam Hamidabad and Rouhollah Haji Abdolvahab Physics Department, Iran University of Science and Technology (IUST),
More information(Crystal) Nucleation: The language
Why crystallization requires supercooling (Crystal) Nucleation: The language 2r 1. Transferring N particles from liquid to crystal yields energy. Crystal nucleus Δµ: thermodynamic driving force N is proportional
More informationMesoscopic simulation of the dynamics of confined complex fluids
Mesoscopic simulation of the dynamics of confined complex fluids M. D. Graham Dept. of Chemical and Biological Engineering Univ. of Wisconsin-Madison Group/Collaborators/support Microfluidics and DNA Richard
More informationA mesoscale investigation of the endothelial glycocalyx and its interaction with blood flow
A mesoscale investigation of the endothelial glycocalyx and its interaction with blood flow Sofia Biagi To cite this version: Sofia Biagi. A mesoscale investigation of the endothelial glycocalyx and its
More informationSurface Forces & Liquid Films (Answers to Exercise Problems)
//5 Surface Forces & Liquid Films (nswers to Exercise Problems) Wuge H. Briscoe wuge.briscoe@bris.ac.uk URL: wugebrisco7.wix.com/briscoegroup Exercise : van der Waals forces & liquid films When octane
More informationQUIZ 2 OPEN QUIZ WHEN TOLD THERE ARE TWO PROBLEMS OF EQUAL WEIGHT. Please answer each question in a SEPARATE book
2.341J MACROMOLECULAR HYDRODYNAMICS Spring 2012 QUIZ 2 OPEN QUIZ WHEN TOLD THERE ARE TWO PROBLEMS OF EQUAL WEIGHT Please answer each question in a SEPARATE book You may use the course textbook (DPL) and
More informationCHARACTERIZATION OF BRANCHED POLYMERS IN SOLUTION (I)
CHARACTERIZATION OF BRANCHED POLYMERS IN SOLUTION (I) Overview: General Properties of Macromolecules in Solution Molar Mass Dependencies Molar Mass Distributions Generalized Ratios Albena Lederer Leibniz-Institute
More informationCleaning Surfaces from Nanoparticles with Polymer Film: Impact of the Polymer Stripping
Cleaning Surfaces from Nanoparticles with Polymer Film: Impact of the Polymer Stripping A. LALLART 1,2,3,4, P. GARNIER 1, E. LORENCEAU 2, A. CARTELLIER 3, E. CHARLAIX 2 1 STMICROELECTRONICS, CROLLES, FRANCE
More information2.1 Traditional and modern applications of polymers. Soft and light materials good heat and electrical insulators
. Polymers.1. Traditional and modern applications.. From chemistry to statistical description.3. Polymer solutions and polymer blends.4. Amorphous polymers.5. The glass transition.6. Crystalline polymers.7.
More informationVISCOELASTIC PROPERTIES OF POLYMERS
VISCOELASTIC PROPERTIES OF POLYMERS John D. Ferry Professor of Chemistry University of Wisconsin THIRD EDITION JOHN WILEY & SONS New York Chichester Brisbane Toronto Singapore Contents 1. The Nature of
More informationComputer Modeling in Bioengineering
Computer Modeling in Bioengineering Theoretical Background, Examples and Software Milos Kojic Harvard School of Public Health, USA University of Kragujevac, Serbia University of Texas Health Science Center
More informationMesoscale simulations of stimuli-sensitive polymer networks
Mesoscale simulations of stimuli-sensitive polymer networks Alexander Alexeev Complex Fluids Modeling and Simulation Group The George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology
More informationInterfacial hoop stress and viscoelastic free surface flow instability. Michael D. Graham University of Wisconsin-Madison
Interfacial hoop stress and viscoelastic free surface flow instability Michael D. Graham University of Wisconsin-Madison Free surface instabilities of viscoelastic flows Eccentric cylinders (Varela-Lopez
More informationAtomic Force Microscopy imaging and beyond
Atomic Force Microscopy imaging and beyond Arif Mumtaz Magnetism and Magnetic Materials Group Department of Physics, QAU Coworkers: Prof. Dr. S.K.Hasanain M. Tariq Khan Alam Imaging and beyond Scanning
More informationAmneh Auben. Abdulrahman Jabr. Diala Abu-Hassan
21 Amneh Auben Abdulrahman Jabr Diala Abu-Hassan Matrix polysaccharides Extracellular matrix (ECM): It s a collection of components that fills the spaces outside the cell or between the cells. ---------
More informationChap. 2. Polymers Introduction. - Polymers: synthetic materials <--> natural materials
Chap. 2. Polymers 2.1. Introduction - Polymers: synthetic materials natural materials no gas phase, not simple liquid (much more viscous), not perfectly crystalline, etc 2.3. Polymer Chain Conformation
More informationLecture 8 Polymers and Gels
Lecture 8 Polymers and Gels Variety of polymeric materials Polymer molecule made by repeating of covalently joint units. Living polymers (not considered in this lecture) long-chain objects connected by
More informationPROPERTIES OF POLYMERS
PROPERTIES OF POLYMERS THEIR CORRELATION WITH CHEMICAL STRUCTURE; THEIR NUMERICAL ESTIMATION AND PREDICTION FROM ADDITIVE GROUP CONTRIBUTIONS Third, completely revised edition By D.W. VÄN KREVELEN Professor-Emeritus,
More informationPolymer Rheology. P Sunthar. Department of Chemical Engineering Indian Institute of Technology, Bombay Mumbai , India
Polymer Rheology P Sunthar Department of Chemical Engineering Indian Institute of Technology, Bombay Mumbai 400076, India P.Sunthar@iitb.ac.in 05 Jan 2010 Introduction Phenomenology Modelling Outline of
More informationDynamics of a tagged monomer: Effects of elastic pinning and harmonic absorption. Shamik Gupta
: Effects of elastic pinning and harmonic absorption Laboratoire de Physique Théorique et Modèles Statistiques, Université Paris-Sud, France Joint work with Alberto Rosso Christophe Texier Ref.: Phys.
More informationSlide of the Seminar
Slide of the Seminar! Dynamics of the Vortex Lines Density in Superfluid Turbulence!! Prof. Anna Pomyalov ERC Advanced Grant (N. 339032) NewTURB (P.I. Prof. Luca Biferale)! Università degli Studi di Roma
More informationThermodynamic Third class Dr. Arkan J. Hadi
5.5 ENTROPY CHANGES OF AN IDEAL GAS For one mole or a unit mass of fluid undergoing a mechanically reversible process in a closed system, the first law, Eq. (2.8), becomes: Differentiation of the defining
More informationElastic Properties of Polymer Networks
J. Mol. Model. 1996, 2, 293 299 Springer-Verlag 1996 Elastic Properties of Polymer Networks Ralf Everaers* and Kurt Kremer Institut für Festkörperforschung, Forschungszentrum Jülich, Postfach 1913, D-52425
More informationSUMMARY A STUDY OF VISCO-ELASTIC NON-NEWTONIAN FLUID FLOWS. where most of body fluids like blood and mucus are non-newtonian ones.
SUMMARY A STUDY OF VISCO-ELASTIC NON-NEWTONIAN FLUID FLOWS Non-Newtonian fluids abound in many aspects of life. They appear in nature, where most of body fluids like blood and mucus are non-newtonian ones.
More informationCOMPLEX FLOW OF NANOCONFINED POLYMERS
COMPLEX FLOW OF NANOCONFINED POLYMERS Connie B. Roth, Chris A. Murray and John R. Dutcher Department of Physics University of Guelph Guelph, Ontario, Canada N1G 2W1 OUTLINE instabilities in freely-standing
More informationAtherosclerosis Initiation Modeled as an Inflammatory Process
Math. Model. Nat. Phenom. Vol. 2, No. 2, 2007, pp. 126-141 Atherosclerosis Initiation Modeled as an Inflammatory Process N. El Khatib 1, S. Génieys and V. Volpert Université Lyon 1, Institut Camille Jordan,
More informationThe Polymers Tug Back
Tugging at Polymers in Turbulent Flow The Polymers Tug Back Jean-Luc Thiffeault http://plasma.ap.columbia.edu/ jeanluc Department of Applied Physics and Applied Mathematics Columbia University Tugging
More informationStructure of a tethered polymer under flow using molecular dynamics and hybrid molecular-continuum simulations
Physica A 362 (2006) 30 35 www.elsevier.com/locate/physa Structure of a tethered polymer under flow using molecular dynamics and hybrid molecular-continuum simulations Rafael Delgado-Buscalioni a, Peter
More informationParash Moni Thakur. Gopal Ch. Hazarika
International Journal of Scientific and Innovative Mathematical Research (IJSIMR) Volume 2, Issue 6, June 2014, PP 554-566 ISSN 2347-307X (Print) & ISSN 2347-3142 (Online) www.arcjournals.org Effects of
More informationUntangling the Mechanics of Entangled Biopolymers
Untangling the Mechanics of Entangled Biopolymers Rae M. Robertson-Anderson Physics Department University of San Diego students/postdocs: Cole Chapman, PhD Tobias Falzone, PhD Stephanie Gorczyca, USD 16
More informationPolymer Dynamics. Tom McLeish. (see Adv. Phys., 51, , (2002)) Durham University, UK
Polymer Dynamics Tom McLeish Durham University, UK (see Adv. Phys., 51, 1379-1527, (2002)) Boulder Summer School 2012: Polymers in Soft and Biological Matter Schedule Coarse-grained polymer physics Experimental
More informationDeficiencies of FENE dumbbell models in describing the rapid stretching of dilute polymer solutions
Deficiencies of FENE dumbbell models in describing the rapid stretching of dilute polymer solutions Indranil Ghosh, Gareth H. McKinley, a) Robert A. Brown, and Robert C. Armstrong b) Department of Chemical
More informationFiber spinning and draw resonance: theoretical background
Fiber spinning and draw resonance: theoretical background dr. ir. Martien Hulsen March 17, 2005 1 Introduction The fiber spinning process is nicely described in the book by Dantig & Tucker ([1], Chapter
More informationLecture 8. Polymers and Gels
Lecture 8 Polymers and Gels Variety of polymeric materials Polymer molecule made by repeating of covalently joint units. Many of physical properties of polymers have universal characteristic related to
More informationpolymers Article Manjesh K. Singh 1, Patrick Ilg 2, Rosa M. Espinosa-Marzal 3, Nicholas D. Spencer 1, * and Martin Kröger 4, *
polymers Article Influence of Chain Stiffness, Grafting Density and Normal Load on the Tribological and Structural Behavior of Polymer Brushes: A Nonequilibrium-Molecular-Dynamics Study Manjesh K. Singh
More informationDifferential relations for fluid flow
Differential relations for fluid flow In this approach, we apply basic conservation laws to an infinitesimally small control volume. The differential approach provides point by point details of a flow
More informationvery elongated in streamwise direction
Linear analyses: Input-output vs. Stability Has much of the phenomenology of boundary la ut analysis of Linearized Navier-Stokes (Cont.) AMPLIFICATION: 1 y. z x 1 STABILITY: Transitional v = (bypass) T
More informationInvestigating platelet motion towards vessel walls in the presence of red blood cells
Investigating platelet motion towards vessel walls in the presence of red blood cells (Complex Fluids in Biological Systems) Lindsay Crowl and Aaron Fogelson Department of Mathematics University of Utah
More informationRole of polymers in the mixing of Rayleigh-Taylor turbulence
Physics Department University of Genova Italy Role of polymers in the mixing of Rayleigh-Taylor turbulence Andrea Mazzino andrea.mazzino@unige.it Guido Boffetta: University of Torino (Italy) Stefano Musacchio:
More informationElasticity of biological gels
Seminar II Elasticity of biological gels Author: Gašper Gregorič Mentor: assoc. prof. Primož Ziherl Ljubljana, February 2014 Abstract In the seminar we discuss the elastic behavior of biological gels,
More informationA new interpretation for the dynamic behavior of complex fluids at the sol-gel transition using the fractional calculus
A new interpretation for the dynamic behavior of complex fluids at the sol-gel transition using the fractional calculus By Stephane Warlus and Alain Ponton Rheol. Acta (009) 48:51-58 Chris Dimitriou NNF
More informationObtaining the Bending Modulus from a Buckled Lipid Membrane
Obtaining the Bending Modulus from a Buckled Lipid Membrane Patrick Diggins, Mingyang Hu, Markus Deserno Department of Physics, Carnegie Mellon University, Pittsburgh PA, USA October 11, 2013 Outline Lipid
More informationModified models of polymer phase separation
Modified models of polymer phase separation Douglas Zhou, Pingwen Zhang,, * and Weinan E,2, LMAM, Peking University, Beijing 0087, People s Republic of China and School of Mathematical Science, Peking
More informationarxiv: v1 [cond-mat.soft] 16 Nov 2014
Polyelectrolytes polarization in non-uniform electric fields Farnoush Farahpour 1, Fathollah Varnik 2, and Mohammad Reza Ejtehadi 1 1 Sharif University of Technology, Department of Physics, P.O. Box 11155-9161,
More informationChemical Engineering 160/260 Polymer Science and Engineering. Lecture 14: Amorphous State February 14, 2001
Chemical Engineering 160/260 Polymer Science and Engineering Lecture 14: Amorphous State February 14, 2001 Objectives! To provide guidance toward understanding why an amorphous polymer glass may be considered
More informationLecture 3. Phenomena at Liquid-gas and Liquid-Liquid interfaces. I
Lecture 3 Phenomena at Liquid-gas and Liquid-Liquid interfaces. I Adsorption at Gas-Liquid interface Measurements of equilibrium adsorption surface tension measurements (Wilhelmy plate) surface analysis
More information