Research and development of antibacterial agent
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1 CHEMICAL INDUSTRY AND ENGINEERING PROGRESS TQ 455 A Research and development of antibacterial agent ZHANG Changhui XIE Yu XU Xuan School of Chemistry and Chemical Engineering Shaanxi University of Science & Technology Xi an Shaanxi China Abstract The recent development of antibacterials used in industry is been reviewed. The development prospect of antibacterial agents in a few years is predicted. The research of organic polymer antibacterial nano inorganic antibacterial and compounded antibacterial will be the focus of future resarch. Key words antibacterial agent; organic antibacterial agent; inorganic antibacterial agent; compounded antibacterial agent ph DNA [1] 05xieyu@sust.edu.cn [2] 1962 E mail
2 [3] Mackeen [4] [6] 13X 1.2 AGZ-330 AB 2 O 4 [7] N TiO 2 ZnO SiO 2 TiO 2 TiO 2 TiO 2 + hv e + h + h + + H 2 O OH + H + e + O 2 O 2 OH + + O 2 + CO 2 + H 2 O TiO 2 TiO 2 [9] [10] 1.3 1% 5 min 98.86% 99.93% [5] 2 2 Ag + TiO 2 TiO 2 [8] ACTICOAT 2.1
3 R DNA RNA [11] 1 n LD 50/m n- 400 [12] n- 350 n [13] 1 Lim [14] NMA Kourai [18] 1995 Torres [15] [19] N P P N P N P N 5 [16] ph=2 N 12 ph 9 [20] Kamazawa A [21] E.Coli S.Aureus + R 1 CH N 3 Cl R R 2 CH 1 R 2 [17] Kamazawa R
4 [22] E Coli S Aureus CH CH 2 n CH 2 CH CH 3 3 N CH [23] 33 Cl Evans R [24] R 2002 [R=CH 2 CH 2 CH 3 CH(CH 3,CH(CH 33 ) 2 ) (CH 2,(CH 22 ) 11 CH 3,(C (CH H 2 ) 215 ) 15 CH 3 3 ] O N O N P + X - 12 Ron Nudel [20] Sauvet G [28] O B-350 [29] [25] Kanazawa [23] [26] Adriana [26] Kamazawa [23] 4- [30] [19] Ikeda Tazuke [27] [31]
5 [31] [9] [10] Noriko Chikaraishi Kasuga [32] Biomacromolecules Ni Cu Zn Science [16] [J] [17] ammonium[j]. Bokin. Bobia [19] / [20] Nudel R Janauer G E Schrier E E composition US [P] J. Polymer. Sci. A Polym. Chem [1]. [M] cationic biocides. synergistic effect on antibacterial activity of polymeric phosphonium and ammonium salts[j]. J. Apply. Polym. Sci [2]. [J] [3]. [M] [25]. DTPC TTPC [4] Mackeen P C Person S Warner S C et al. Silver-coated nylon fiber as an antibacterial agent[j]. Antimicrobial Agents and Chemotherapy [5]. [J] [6]. [J] [7] Shiau Y K Wu C H. Antimicrobial composition supported on a honeycomb shaped substrate US [P] [8]. [J] [J]. ZnO [J]. [11]. [J] [12] Entsar l Rabea Mohamed E T Badawy Christian V Stevens et al. Chitosan as antimicrobial agent applications and mode of action[j]. [13] HA-SOO SEONG Hyun Suk Whang Sohk-won Ko. Synthesis of a quanternary ammonium derivative of chitooligosaccharide as antimicrobial agent for cellulosic[j]. Journal of Applied Polymer [14] Lim Sang-Hoon Hudson Samuel M. Synthesis and antimicrobial activity of a water-soluble chitosan derivative with a fiber-reactive group[j]. Carbohydr. Res [15] Torres Y R Berlinck R G S Nascimento G G F et al. Antibacterial activity against resistant bacteria and cytotoxiciy of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis[j]. Toxicon ASQA. [J] [18] Kourai. Synthesis and antibacterial activity of unsaturated quaternary ~50.. [J]. et al. Water insoluble disinfectant [21] Kamazawa A Ikeda T Endo T. Novel polycationic biocides synthesis and antibacterial activity of polymeric phosphonium salts[j]. [22] Kamazawa A Ikeda T Endo T. Polymeric phosphonium salts as an novel class of cationic biocides synthesis antibacterial acrsvity of polymers releasing phoaphonium biocides[j]. J. Polym. A Polym. Chem [23] Kamazawa A Ikeda T Endo T. Phosphonium salts as a novel class of [24]. [J] [J] [26] Adriana Popa Davidescu C M Trif R et al. Study of quaternary onium salts grafted on polymers antibacterial activity of quaternary
6 salts grafted on gel-type styrene 3 / divinylbenzend copolymers[j]. Reactive and Functional Polymers [27] Ikeda T Tazuke S et al. Polycationic biocides with pendant active groups molecular weight dependence of antibacterial activity[j]. Antimicrob Agents Chemother [28] Sauvel G Dupond S Znierski et al. Production of silyl quaternary [J] [30]. [J] [31]. [J] [32] Noriko Chikaraishi Kasuga Kiyoshi Sekino Motoki Ishikawa et al. ammonium compounds[j]. J. Apply. Polym. Sci Synthesis structural characterization and antimicrobial activities of zinc complexes with four thiosem icarbazone and two semicarbazone ligands [29]. [J]. Journal of Inorganic Biochemistry ICIS BPA hgjx@chemach.com http //hgjx.chinajournal.net.cn ISSN CN /O editor@intchem.net advert@intchem.net CN /TQ ISSN hxgcs@yahoo.com.cn
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